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  1. Retrobulbar irradiation for thyroid eye disease (HTG94)

    Evidence-based recommendations on retrobulbar irradiation for thyroid eye disease. This involves using radiation to target the tissue behind the eyeball and reduce inflammation.

    HealthTech guidance
    Published
    14 December 2005
    View recommendations

    Sections for HTG94

  2. Intermittent urinary catheters: catheter selection:- For patients performing intermittent self-catheterisation over the long term, what is the clinical and cost effectiveness of single-use non-coated versus single-use hydrophilic versus single-use gel reservoir versus reusable non-coated catheters with regard to the following outcomes: symptomatic urinary tract infections, urinary tract infection-associated bacteraemia, mortality, patient comfort and preference, quality of life, and clinical symptoms of urethral damage?

    selection:- For patients performing intermittent self-catheterisation over the long term, what is the clinical and cost effectiveness of...

    Research recommendation
    Published
    9 June 2015

  3. Intravenous fluid therapy in adults in hospital (QS66)

    This quality standard covers managing intravenous (IV) fluid therapy safely and effectively for adults in hospital. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    14 August 2014
    View quality statements

    Sections for QS66

  4. Is primary radical cystectomy more effective than primary intravesical BCG (Bacille Calmette-Guérin) in high risk non-muscle-invasive bladder cancer, in terms of quality of life and cancer-specific outcomes?

    (Bacille Calmette-Guérin) in high risk non-muscle-invasive bladder cancer, in terms of quality of life and cancer-specific outcomes? Any...

    Research recommendation
    Published
    9 June 2015

  5. Physical activity in the workplace (PH13)

    This guideline covers how to encourage employees to be physically active. The aim is to increase the working population’s physical activity levels.

    Public health guideline
    Published
    28 May 2008
    View recommendations

    Sections for PH13

  6. Osteoporosis: assessing the risk of fragility fracture (CG146)

    This guideline covers assessing the risk of fragility fracture in people aged 18 and over with osteoporosis. It aims to provide guidance on the selection and use of risk assessment tools in the care of adults at risk of fragility fractures in all NHS settings.

    Clinical guideline
    Last updated
    7 February 2017
    View recommendations

    Sections for CG146

  7. Digital technologies for applying algorithms to spirometry to support asthma and COPD diagnosis in primary care and community diagnostic centres: early-use assessment (HTG776)

    Evidence-based recommendations on the early use of digital technologies for applying algorithms to spirometry to support asthma and chronic obstructive pulmonary disease (COPD) diagnosis in primary care and community diagnostic centres.

    HealthTech guidance
    Published
    2 April 2026
    View recommendations

    Sections for HTG776

  8. Stapled haemorrhoidopexy for the treatment of haemorrhoids (TA128)

    Evidence-based recommendations on stapled haemorrhoidopexy for treating haemorrhoids in adults.

    Technology appraisal guidance
    Published
    26 September 2007
    View recommendations

    Sections for TA128

  9. Epiretinal brachytherapy for wet age-related macular degeneration (AMD) should only be used in the context of research. Research studies should address whether epiretinal brachytherapy reduces the progression of wet AMD and whether it can reduce the number of injections of antivascular endothelial growth factor agents (anti-VEGF) required. Long-term outcomes should be reported.

    antivascular endothelial growth factor agents (anti-VEGF) required. Long-term outcomes should be reported. Any explanatory notes(if...

    Research recommendation
    Published
    9 June 2015

  10. Care and support of people growing older with learning disabilities (NG96)

    This guideline covers care and support for adults with learning disabilities as they grow older. It covers identifying changing needs, planning for the future, and delivering services including health, social care and housing. It aims to support people to access the services they need as they get older.

    NICE guideline
    Published
    11 April 2018
    View recommendations

    Sections for NG96

  11. Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia (TA394)

    Evidence-based recommendations on evolocumab (Repatha) for treating primary hypercholesterolaemia or mixed dyslipidaemia in adults.

    Technology appraisal guidance
    Published
    22 June 2016
    View recommendations

    Sections for TA394

  12. Ciclosporin for treating dry eye disease that has not improved despite treatment with artificial tears (TA369)

    Evidence-based recommendations on ciclosporin (Ikervis) for dry eye disease in adults that has not improved despite treatment with artificial tears.

    Technology appraisal guidance
    Published
    16 December 2015
    View recommendations

    Sections for TA369

  13. Further research into percutaneous atherectomy of femoropopliteal arterial lesions with plaque excision devices should take the form of well-conducted trials, which should define patient selection, treatment protocols and location and types of arterial lesions treated, and report long-term patency outcomes. NICE may review this procedure on publication of further evidence.

    protocols and location and types of arterial lesions treated, and report long-term patency outcomes. NICE may review this procedure on...

    Research recommendation
    Published
    9 June 2015

  14. Cardiovascular disease prevention: cardiovascular risk assessment for people with bipolar, schizophrenia or other psychoses (IND150)

    This indicator covers the percentage of patients aged between 25 and 84 years with schizophrenia, bipolar affective disorder and other psychoses (excluding those with pre-existing cardiovascular disease, chronic kidney disease, familial hypercholesterolaemia or type 1 diabetes) who have had a full formal cardiovascular disease risk assessment performed in the preceding 12 months. It measures outcomes that reflect the quality of care or processes linked by evidence to improved outcomes. This indicator was previously published as NM120

    General practice indicators suitable for use in QOF
    Published
    3 August 2015

  15. Image-guided percutaneous laser ablation for primary and secondary liver tumours (HTG722)

    Evidence-based recommendations on image-guided percutaneous laser ablation for primary and secondary liver tumours. This involves heating up liver tissue to destroy tumours.

    HealthTech guidance
    Published
    16 May 2024
    View recommendations

    Sections for HTG722

  16. Temperature control to improve neurological outcomes after cardiac arrest (HTG710)

    Evidence-based recommendations on temperature control to improve neurological outcomes after cardiac arrest. This involves controlling a person’s body temperature while they are still unconscious after their heart has been restarted. Either their body is kept at a normal temperature of between 36.5°C and 37.5°C to prevent fever, or it is cooled to between 32.0°C and 36.0°C (therapeutic hypothermia).

    HealthTech guidance
    Published
    23 January 2024
    View recommendations

    Sections for HTG710

  17. Physical activity for children and young people (PH17)

    This guideline covers promoting physical activity for children and young people aged under 18 at home, preschool, school and in the community. It includes raising awareness of the benefits of physical activity, listening to what children and young people want, planning and providing spaces and facilities, and helping families build physical activity into their daily lives.

    Public health guideline
    Published
    28 January 2009
    View recommendations

    Sections for PH17

  18. What are the long-term outcomes, both psychotic and nonpsychotic, for children and young people with attenuated or transient psychotic symptoms suggestive of a developing psychosis, and can the criteria for 'at risk states' be refined to better predict those who will and those who will not go on to develop psychosis?

    Recommendation ID CG155/1 Question What are the long-term outcomes, both psychotic and nonpsychotic, for children and young people with

    Research recommendation
    Published
    9 June 2015

  19. Further research on the efficacy and safety of intranasal phototherapy for allergic rhinitis should include: details of patient selection including medication use; underlying medical conditions; the intensity, duration and wavelength of light used; patient-reported outcomes; comparison with existing treatments; and the effects of repeated long-term use. NICE may update the guidance if further evidence is published.

    outcomes; comparison with existing treatments; and the effects of repeated long-term use. NICE may update the guidance if further...

    Research recommendation
    Published
    10 December 2018

  20. NICE encourages further research and data collection on endoscopic full thickness removal of non-lifting colonic polyps and may update the guidance on publication of further evidence. This should include safety and efficacy outcomes such as perforation, bleeding, the need for immediate re-intervention, inadequate resection and longer-term follow-up of patients found to have malignant disease.

    the need for immediate re-intervention, inadequate resection and longer-term follow-up of patients found to have malignant disease. Any...

    Research recommendation
    Published
    12 October 2018

  21. Fetal alcohol spectrum disorder (QS204)

    This quality standard covers assessing and diagnosing fetal alcohol spectrum disorder (FASD) in children and young people. It also covers support during pregnancy to prevent FASD. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    16 March 2022
    View quality statements

    Sections for QS204

  22. Falls: assessment and prevention in older people and in people 50 and over at higher risk (NG249)

    This guideline covers assessing risk of falling and interventions to prevent falls in all people aged 65 and over, and people aged 50 to 64 who are at higher risk of falls. It aims to reduce the risk and incidence of falls, and the associated distress, pain, injury, loss of confidence, loss of independence and mortality.

    NICE guideline
    Published
    29 April 2025
    View recommendations

    Sections for NG249

  23. Implantation of a sphenopalatine ganglion stimulation device for chronic cluster headache (HTG378)

    Evidence-based recommendations on implantation of a sphenopalatine ganglion stimulation device for chronic cluster headache. This involves implanting a device into the cheek to stimulate a group of nerves called the sphenopalatine ganglion.

    HealthTech guidance
    Published
    26 June 2015
    View recommendations

    Sections for HTG378

  24. SeHCAT (tauroselcholic [75 selenium] acid) for diagnosing bile acid diarrhoea (HTG598)

    Evidence-based recommendations on SeHCAT (tauroselcholic [75 selenium] acid) for diagnosing bile acid diarrhoea.

    HealthTech guidance
    Published
    17 November 2021
    View recommendations

    Sections for HTG598

  25. Minimally invasive percutaneous surgical techniques with internal fixation for correcting hallux valgus (HTG723)

    Evidence-based recommendations on minimally invasive percutaneous surgical techniques with internal fixation for correcting hallux valgus. This involves cutting into the big toe to remove the bunion and securing the bones at the front of the foot.

    HealthTech guidance
    Published
    20 June 2024
    View recommendations

    Sections for HTG723

  26. Insertion of hydrogel keratoprosthesis (HTG42)

    Evidence-based recommendations on insertion of hydrogel keratoprosthesis. This involves putting an artificial cornea into place in a pocket made in the front part of the eye.

    HealthTech guidance
    Published
    23 June 2004
    View recommendations

    Sections for HTG42

  27. Valve-in-valve TAVI for aortic bioprosthetic valve dysfunction (HTG518)

    Evidence-based recommendations on valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) for aortic bioprosthetic valve dysfunction in adults. This involves placing a new bioprosthetic valve inside a failing bioprosthetic valve.

    HealthTech guidance
    Published
    26 June 2019
    View recommendations

    Sections for HTG518

  28. Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure from high spinal cord injuries (HTG679)

    Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure from high spinal cord injuries. This involves keyhole abdominal surgery. The aim is to stimulate and possibly strengthen the diaphragm to help people breathe without a ventilator.

    HealthTech guidance
    Published
    24 May 2023
    View recommendations

    Sections for HTG679

  29. Biodegradable subacromial spacer insertion for rotator cuff tears (HTG702)

    Evidence-based recommendations on biodegradable subacromial spacer insertion for rotator cuff tears. This involves inserting a balloon-shaped device between the top of the shoulder blade and the upper arm bone to reduce pain and improve shoulder function.

    HealthTech guidance
    Published
    15 November 2023
    View recommendations

    Sections for HTG702

  30. Percutaneous (non-thoracoscopic) epicardial catheter radiofrequency ablation for atrial fibrillation (HTG186)

    Evidence-based recommendations on percutaneous (non-thoracoscopic) epicardial catheter radiofrequency ablation for atrial fibrillation. This involves using heat to destroy selected areas of the heart to prevent the abnormal electrical impulses responsible for atrial fibrillation.

    HealthTech guidance
    Published
    27 March 2009
    View recommendations

    Sections for HTG186

  31. Neurostimulation of lumbar muscles for refractory non-specific chronic low back pain (HTG641)

    Evidence-based recommendations on neurostimulation of lumbar muscles for refractory non-specific chronic low back pain in adults. This involves implanting a pulse generator under the skin of the upper buttock or lower back, which the person can use to manage their pain.

    HealthTech guidance
    Published
    22 September 2022
    View recommendations

    Sections for HTG641

  32. iTind for lower urinary tract symptoms caused by benign prostatic hyperplasia (MIB306)

    NICE has developed a medtech innovation briefing (MIB) on iTind for lower urinary tract symptoms caused by benign prostatic hyperplasia .

    Medtech innovation briefing
    Published
    21 September 2022

  33. Contraception (QS129)

    This quality standard covers contraception for women, including emergency contraception. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    8 September 2016
    View quality statements

    Sections for QS129

  34. Reslizumab for treating severe eosinophilic asthma (TA479)

    Evidence-based recommendations on reslizumab (Cinqaero) for treating severe eosinophilic asthma in adults.

    Technology appraisal guidance
    Published
    4 October 2017
    View recommendations

    Sections for TA479

  35. Evinacumab for treating homozygous familial hypercholesterolaemia in people 12 years and over (TA1002)

    Evidence-based recommendations on evinacumab (Evkeeza) for treating homozygous familial hypercholesterolaemia in people 12 years and over.

    Technology appraisal guidance
    Published
    11 September 2024
    View recommendations

    Sections for TA1002

  36. Pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma (TA540)

    Evidence-based recommendations on pembrolizumab (Keytruda) for treating relapsed or refractory classical Hodgkin lymphoma in adults.

    Technology appraisal guidance
    Last updated
    1 May 2024
    View recommendations

    Sections for TA540

  37. Blinatumomab for previously treated Philadelphia-chromosome-negative acute lymphoblastic leukaemia (TA450)

    Evidence-based recommendations on blinatumomab (Blincyto) for treating Philadelphia-chromosome-negative precursor B-cell acute lymphoblastic leukaemia in adults.

    Technology appraisal guidance
    Published
    28 June 2017
    View recommendations

    Sections for TA450

  38. Patiromer for treating hyperkalaemia (TA623)

    Evidence based recommendations on patiromer (Veltassa) for treating hyperkalaemia in adults.

    Technology appraisal guidance
    Published
    13 February 2020
    View recommendations

    Sections for TA623

  39. Pembrolizumab for neoadjuvant and adjuvant treatment of triple-negative early or locally advanced breast cancer (TA851)

    Evidence-based recommendations on pembrolizumab (Keytruda) for neoadjuvant and adjuvant treatment of triple-negative early or locally advanced breast cancer in adults.

    Technology appraisal guidance
    Published
    14 December 2022
    View recommendations

    Sections for TA851

  40. CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack (HTG724)

    Evidence-based recommendations on CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack.

    HealthTech guidance
    Published
    31 July 2024
    View recommendations

    Sections for HTG724

  41. AposHealth for knee osteoarthritis (HTG671)

    Evidence-based recommendations on AposHealth for knee osteoarthritis.

    HealthTech guidance
    Published
    11 April 2023
    View recommendations

    Sections for HTG671

  42. Acute coronary syndromes in adults (QS68)

    This quality standard covers diagnosing and managing acute coronary syndromes in adults (aged 18 and over). Acute coronary syndromes are medical emergencies that include myocardial infarction (heart attack) and unstable angina (unexpected, severe chest pain). It describes high-quality care in priority areas for improvement.

    Quality standard
    Last updated
    18 November 2020
    View quality statements

    Sections for QS68

  43. Diagnostics advisory committee

    Membership details, terms of reference, future meeting dates and past meeting minutes for our diagnostics advisory committee.

  44. Diagnostics advisory committee

    Membership details, terms of reference, future meeting dates and past meeting minutes for our diagnostics advisory committee.

  45. Durvalumab for maintenance treatment of unresectable non-small-cell lung cancer after platinum-based chemoradiation (TA798)

    Evidence-based recommendations on durvalumab (Imfinzi) for locally advanced unresectable non-small-cell lung cancer after platinum-based chemoradiation in adults.

    Technology appraisal guidance
    Published
    22 June 2022
    View recommendations

    Sections for TA798

  46. Arthroscopic knee washout, with or without debridement, for the treatment of osteoarthritis (HTG148)

    Evidence-based recommendations on arthroscopic knee washout, with or without debridement, for the treatment of osteoarthritis. This involves flushing the joint with fluid, which is introduced through small incisions in the knee.

    HealthTech guidance
    Published
    22 August 2007
    View recommendations

    Sections for HTG148

  47. Cataracts in adults: management (NG77)

    This guideline covers managing cataracts in adults aged 18 and over. It aims to improve care before, during and after cataract surgery by optimising service organisation, referral and surgical management, and reducing complications. It further aims to improve the availability of information for people with cataracts before, during and after cataract surgery.

    NICE guideline
    Published
    26 October 2017
    View recommendations

    Sections for NG77

  48. Evidence on the safety and efficacy of laparoscopic renal denervation for loin pain haematuria syndrome is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page. Further research should report details of patient selection, technique used and long-term follow-up outcomes

    research should report details of patient selection, technique used and long-term follow-up outcomes Any explanatory notes(if...

    Research recommendation
    Published
    5 November 2021

  49. Endoscopic saphenous vein harvest for coronary artery bypass grafting (HTG342)

    Evidence-based recommendations on endoscopic saphenous vein harvest for coronary artery bypass grafting. This involves removing the vein under endoscopic guidance through a small cut near the knee (keyhole surgery).

    HealthTech guidance
    Published
    25 June 2014
    View recommendations

    Sections for HTG342

  50. Microwave ablation of hepatocellular carcinoma (HTG138)

    Evidence-based recommendations on microwave ablation of hepatocellular carcinoma. This involves using heat from microwave energy to destroy the cancer cells.

    HealthTech guidance
    Published
    28 March 2007
    View recommendations

    Sections for HTG138