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Evidence-based recommendations on adalimumab, etanercept, infliximab and abatacept for adults with moderate rheumatoid arthritis who have tried conventional DMARDs but they have not worked.

Result type

Technology appraisal guidance

Published

14 July 2021

Evidence-based recommendations on carotid artery stent placement for symptomatic extracranial carotid stenosis. This involves using a metal mesh called a stent to widen the narrowed carotid artery.

Result type

HealthTech guidance

Published

27 April 2011

Evidence-based recommendations on KardiaMobile for detecting atrial fibrillation.

Result type

HealthTech guidance

Last updated

25 July 2023

Evidence-based recommendations on micropressure therapy for refractory Ménière's disease. This involves inserting a grommet (small tube) through the eardrum into the middle ear and blowing air at low pressure into the inner ear.

Result type

HealthTech guidance

Published

26 April 2012

including digital tools, diagnostics and medical devices, is transforming patient care. But with thousands of products on the market,...

Evidence-based recommendations on selective internal radiation therapy (SIRT) for primary hepatocellular carcinoma. This involves infusion of microspheres loaded with yttrium-90, which aims to deliver radiation directly into the tumour, minimising the risk of radiation damage to healthy surrounding tissues.

Result type

HealthTech guidance

Published

23 July 2013

Evidence-based recommendations on processed nerve allografts to repair peripheral nerve discontinuities. This involves using a specially treated nerve (an allograft) taken from a human donor after death to bridge the gap in the nerve.

Result type

HealthTech guidance

Published

22 November 2017

This guideline covers identifying children, young people and adults with symptoms that could be caused by cancer. It outlines appropriate investigations in primary care, and selection of people to refer for a specialist opinion. It aims to help people understand what to expect if they have symptoms that may suggest cancer.

Result type

NICE guideline

Last updated

15 April 2026

Evidence-based recommendations on radiation therapy for early Dupuytren’s contractures in adults. This involves directing low energy X-rays at the affected tissue.

Result type

HealthTech guidance

Published

21 December 2016

Evidence-based recommendations on ruxolitinib (Jakavi) for treating acute graft versus host disease that has an inadequate response to corticosteroids in people 12 years and over.

Result type

Technology appraisal guidance

Published

15 April 2025

In development Reference number: GID-TA11559 Expected publication date:  10 June 2026

Result type

Technology appraisal guidance

Status

In development

Evidence-based recommendations on darolutamide (Nubeqa) for treating hormone-relapsed prostate cancer in adults at high risk of developing metastatic disease.

Result type

Technology appraisal guidance

Published

25 November 2020

Evidence-based recommendations on endoscopic injection of bulking agents for gastro-oesophageal reflux disease. This involves injecting a filler into the junction using a catheter to make the entry to the stomach narrower, so that the contents of the stomach cannot pass back.

Result type

HealthTech guidance

Published

28 April 2004

Evidence-based recommendations on selective dorsal rhizotomy for spasticity in cerebral palsy. This involves cutting nerves in the lower spine that are responsible for muscle rigidity.

Result type

HealthTech guidance

Published

15 December 2010

Evidence-based recommendations on autologous blood injection for plantar fasciitis. This involves supplying the connective tissue with growth factors that promote the healing process.

Result type

HealthTech guidance

Published

23 January 2013

Evidence-based recommendations on deep brain stimulation for tremor and dystonia (excluding Parkinson's disease). This involves planting electrodes in the brain and generating electrical currents to help control the tremor or dystonia.

Result type

HealthTech guidance

Published

23 August 2006

Evidence-based recommendations on cabozantinib (Cabometyx) for previously treated advance renal cell carcinoma in adults.

Result type

Technology appraisal guidance

Published

9 August 2017

Evidence-based recommendations on intravascular lithotripsy for calcified arteries in peripheral arterial disease. This involves using pressure waves to soften arterial plaque and widen the artery to improve blood flow.

Result type

HealthTech guidance

Published

3 January 2024

Evidence-based recommendations on percutaneous endoscopic laser thoracic discectomy. This involves using a laser to heat and destroy some of the inside of the disc and shrink the part that is sticking out.

Result type

HealthTech guidance

Published

27 May 2004

Evidence-based recommendations on extracorporeal shockwave therapy for Peyronie's disease. This involves using vibrations caused by sound waves to treat the affected tissue.

Result type

HealthTech guidance

Published

17 December 2003

Evidence-based recommendations on intraoperative electron beam radiotherapy for locally advanced and locally recurrent colorectal cancer. This involves delivering electron beam radiation directly to the tumour during surgery. The aim is to stop the cancer from coming back and spreading further.

Result type

HealthTech guidance

Published

6 June 2023

Evidence-based recommendations on radiofrequency treatment for haemorrhoids in adults. This involves using radiofrequency energy to shrink the haemorrhoids.

Result type

HealthTech guidance

Published

23 August 2017

Evidence-based recommendations on bortezomib (Velcade) for untreated mantle cell lymphoma in adults.

Result type

Technology appraisal guidance

Published

16 December 2015

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for native aortic valve regurgitation. This involves implanting a replacement valve inside the faulty native valve.

Result type

HealthTech guidance

Published

24 June 2025

Evidence-based recommendations on minimally invasive video-assisted thyroidectomy. This involves inserting instruments through a small cut (keyhole surgery) to remove part or all of the gland.

Result type

HealthTech guidance

Published

23 August 2014

Evidence-based recommendations on percutaneous closure of patent foramen ovale for recurrent migraine. This involves passing a device through a large vessel in the groin up into the heart and closing/blocking the hole in the wall of the heart.

Result type

HealthTech guidance

Published

15 December 2010

Evidence-based recommendations on filgotinib (Jyseleca) for moderately to severely active ulcerative colitis in adults when conventional or biological treatment cannot be tolerated, or the disease has responded inadequately or lost response to treatment.

Result type

Technology appraisal guidance

Published

1 June 2022

Evidence-based recommendations on arthroscopic radiofrequency chondroplasty for discrete chondral defects of the knee. This involves using a radiofrequency probe to heat and smooth any defects and rough edges in the cartilage.

Result type

HealthTech guidance

Published

27 May 2014

Evidence-based recommendations on the E-vita open plus for treating complex aneurysms and dissections of the thoracic aorta.

Result type

HealthTech guidance

Last updated

1 October 2018

Evidence-based recommendations on photorefractive (laser) surgery for the correction of refractive errors. This involves using a special laser to permanently change the shape of the cornea.

Result type

HealthTech guidance

Published

22 March 2006

Evidence-based recommendations on endoscopic transluminal pancreatic necrosectomy in adults. This involves removing dead tissue from the pancreas.

Result type

HealthTech guidance

Published

23 November 2016

Evidence-based recommendations on retrograde uretral sphincterometry. This involves passing fluid through a small, cone-shaped device placed into the urethra to display the pressure needed to open the urethra sphincter.

Result type

HealthTech guidance

Published

26 April 2006

Evidence-based recommendations on insertion of metal rib reinforcements to stabilise a flail chest wall. This involves using metal (usually titanium) to stabilise the ‘flail’ segment of chest wall.

Result type

HealthTech guidance

Published

27 October 2010

Evidence-based recommendations on intramural urethral bulking procedures for stress urinary incontinence in women. Intramural urethral bulking aims to augment the urethral wall and increase the urethral closure force.

Result type

HealthTech guidance

Published

23 November 2005

Evidence-based recommendations on sinus tarsi implant insertion for mobile flatfoot. This involves surgery to insert an implant just above the heel bone, with the aim of correcting the condition and improving symptoms.

Result type

HealthTech guidance

Published

22 July 2009

Evidence-based recommendations on radiofrequency valvotomy for pulmonary atresia. This involves making a hole in the blocked valve, and inserting and inflating a small balloon to widen it.

Result type

HealthTech guidance

Published

27 October 2004

Evidence-based recommendations on prasugrel (Efient) with percutaneous coronary intervention for treating acute coronary syndromes in adults.

Result type

Technology appraisal guidance

Published

23 July 2014

Read biographies of the members of our quality standards advisory committee.

Read biographies of the members of our quality standards advisory committee.

Evidence-based recommendations on Synergo for non-muscle-invasive bladder cancer.

Result type

HealthTech guidance

Published

30 November 2021

Early value assessment (EVA) guidance on digital technologies for managing non-specific low back pain in people 16 years and over.

Result type

HealthTech guidance

Last updated

30 April 2026

In development Reference number: GID-TA11669 Expected publication date:  03 September 2026

Result type

Technology appraisal guidance

Status

In development

Evidence-based recommendations on implantation of a duodenal-jejunal bypass sleeve for managing obesity. This involves attaching a sleeve to the upper part of the bowel to slow digestion.

Result type

HealthTech guidance

Published

27 November 2013

Evidence-based recommendations on bilateral cervicosacropexy (CESA) or vaginosacropexy (VASA) using mesh for pelvic organ prolapse in adults. This involves replacing weakened or stretched ligaments that support the uterus and hold the pelvic organs in place with mesh tape.

Result type

HealthTech guidance

Published

4 March 2020

Evidence-based recommendations on pressurised intraperitoneal aerosol chemotherapy for peritoneal carcinomatosis in adults. This involves spraying the inside of the peritoneal cavity with chemotherapy.

Result type

HealthTech guidance

Published

28 October 2020

NICE has developed a medtech innovation briefing (MIB) on the Juxta CURES adjustable compression system for treating venous leg ulcers

Result type

Medtech innovation briefing

Published

25 March 2015

Evidence-based recommendations on photodynamic therapy (PDT) for localised inoperable endobronchial cancer (non-small-cell lung cancer). This involves injecting a photosensitising agent into the body that is activated by laser light to destroy the cancerous tissue.

Result type

HealthTech guidance

Published

23 November 2005

interventional procedures guidance page. Further research should report details of patient selection, technique used and long-term...

Result type

Research recommendation

Published

5 November 2021

Evidence-based recommendations on dabrafenib (Tafinlar) with trametinib (Mekinist) for resected stage III, BRAF V600 mutation-positive melanoma in adults.

Result type

Technology appraisal guidance

Published

17 October 2018

Evidence-based recommendations on endoscopic radiofrequency therapy of the anal sphincter for faecal incontinence. This involves applying radiofrequency energy to the anal wall, with the aim of inducing muscle changes to improve muscle tone and help control bowel movement.

Result type

HealthTech guidance

Published

25 May 2011