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Guidance programme

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Showing 4246 to 4260 of 8314 results

  1. Agitation and delirium:- What is the best way to control delirium, with or without agitation, in the dying person, without causing undue sedation and without shortening life?

    Recommendation ID NG31/2 Question Agitation and delirium:- What is the best way to control delirium, with or without agitation, in the

    Research recommendation
    Published
    27 January 2016

  2. A high-quality test accuracy study is needed for the BRAHMS sFlt‑1 Kryptor/BRAHMS PLGF plus Kryptor PE ratio test, using thresholds defined by the company, done in a population independent from that used to establish the test's thresholds, and with the test used as intended in the NHS. Further research is recommended on repeat PLGF (placental growth factor)‑based testing, with standard clinical assessment, in women presenting with suspected preterm pre-eclampsia, who have had a previous PLGF‑based test result (see section 3.7 ). This should include: - exploring the different scenarios in which repeat testing may be indicated - the appropriate intervals between PLGF‑based tests - the diagnostic accuracy of repeat PLGF‑based testing in women with suspected preterm pre-eclampsia. Further research is recommended into how well the tests work when women are pregnant with more than 1 baby to find out if different cut-offs are needed (see section 3.15 ).

    Recommendation ID DG49/01 Question A high-quality test accuracy study is needed for the BRAHMS sFlt‑1 Kryptor/BRAHMS PLGF plus Kryptor

    Research recommendation
    Published
    4 August 2022

  3. What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the home?

    Recommendation ID NG149/3 Question What is the minimum air exchange rate to minimise the health effects of poor indoor air quality in the

    Research recommendation
    Published
    10 February 2020

  4. Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung function in infants and children with cystic fibrosis?

    Recommendation ID NG78/2 Question Airway clearance techniques:- How effective are daily airway clearance techniques in maintaining lung

    Research recommendation
    Published
    6 November 2018

  5. Allogeneic stem cell transplantation:- What is the effectiveness of combined autologous–allogeneic stem cell transplantation compared with autologous stem cell transplantation, plus consolidation and maintenance treatment in chemosensitive patients at first response or first relapse?

    Recommendation ID NG35/4 Question Allogeneic stem cell transplantation:- What is the effectiveness of combined autologous–allogeneic stem

    Research recommendation
    Published
    5 April 2016

  6. Additional research could help address uncertainties in the evidence, although the case for cost savings remains unlikely. Although the committee acknowledged that the Game et al. (2018) RCT was well conducted, it felt that additional research could help resolve some uncertainties around the cost and clinical case for 3C Patch. Specifically, research identifying the most appropriate stopping rule, and the associated clinical outcomes of implementing the rule, would help address key uncertainties within the cost case. Additional collection of resource use data on unhealed hard-to-heal ulcers could also reduce uncertainty in the cost case. Further to this, evidence could be collected on an UrgoStart-experienced population, as this would be reflective of current NHS care. Clinical experts thought a trial on this population would be feasible. The committee concluded that although further research could be done, on balance it was unlikely to result in a cost-saving case for 3C Patch based on the decision problem evaluated in this guidance

    Recommendation ID MTG66/01 Question Additional research could help address uncertainties in the evidence, although the case for cost savings

    Research recommendation
    Published
    8 April 2022

  7. Amitriptyline to prevent recurrent migraine:- Is amitriptyline a clinically and cost effective prophylactic treatment for recurrent migraine?

    Recommendation ID CG150/1 Question Amitriptyline to prevent recurrent migraine:- Is amitriptyline a clinically and cost effective prophylactic

    Research recommendation
    Published
    9 August 2021

  8. ALT values for children and young people:- Further research should be undertaken to examine whether the upper limit of normal ALT values for adults (below 30 IU/ml for males and below 19 IU/ml for females) are appropriate for use in children and young people with chronic hepatitis B when making decisions on when to initiate treatment.

    Recommendation ID CG165/2 Question ALT values for children and young people:- Further research should be undertaken to examine whether

    Research recommendation
    Published
    9 June 2015

  9. What local anaesthetic techniques are most effective for women having surgical abortion?

    Recommendation ID NG140/5 Question What local anaesthetic techniques are most effective for women having surgical abortion? Any

    Research recommendation
    Published
    8 November 2019

  10. What is the optimal regimen for general anaesthesia for women having surgical abortion?

    Recommendation ID NG140/7 Question What is the optimal regimen for general anaesthesia for women having surgical abortion? Any explanatory

    Research recommendation
    Published
    8 November 2019

  11. Ambulatory oxygen to improve outcomes in idiopathic pulmonary fibrosis:- Does ambulatory oxygen improve outcomes in idiopathic pulmonary fibrosis?

    Recommendation ID CG163/4 Question Ambulatory oxygen to improve outcomes in idiopathic pulmonary fibrosis:- Does ambulatory oxygen improve

    Research recommendation
    Published
    9 June 2015

  12. Early pregnancy assessment units: A national evaluation of early pregnancy assessment unit service provision should be carried out to identify factors affecting outcomes. Factors should include whether care is provided in a dedicated unit, staffing configuration and opening hours of dedicated services. Outcomes should include both process (service) outcomes and pregnancy-related outcomes. Data collected should be used to analyse the cost effectiveness of early pregnancy assessment units compared with other models of care.

    Recommendation ID NG126/01 Question Early pregnancy assessment units: A national evaluation of early pregnancy assessment unit service

    Research recommendation
    Published
    17 December 2021

  13. Angioplasty versus bypass surgery for treating people with critical limb ischaemia caused by disease of the infra-geniculate arteries:- What is the clinical and cost effectiveness of a 'bypass surgery first' strategy compared with an 'angioplasty first' strategy for treating people with critical limb ischaemia caused by disease of the infra-geniculate (below the knee) arteries?

    Recommendation ID CG147/1 Question Angioplasty versus bypass surgery for treating people with critical limb ischaemia caused by disease

    Research recommendation
    Published
    9 June 2015

  14. An instrument to measure quality of life in people with glaucoma:- What instrument should be used to measure health related quality of life in people with glaucoma?

    Recommendation ID NG81/3 Question An instrument to measure quality of life in people with glaucoma:- What instrument should be used to

    Research recommendation
    Published
    18 October 2018

  15. What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

    Recommendation ID NG140/1 Question What is the optimal antibiotic prophylaxis regimen for women who are having a surgical abortion?

    Research recommendation
    Published
    8 November 2019