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Evidence-based recommendations on deep brain stimulation for refractory chronic pain syndromes (excluding headache). This involves stimulating a precise area of the brain using an electrode to treat the chronic pain.

Result type

HealthTech guidance

Published

23 March 2011

Evidence-based recommendations on percutaneous radiofrequency ablation for primary or secondary lung cancers. This involves inserting 1 or more electrodes (needle-like probes) through the chest into the lung and using an electrical current to produce heat to destroy the cancer cells.

Result type

HealthTech guidance

Published

15 December 2010

Evidence-based recommendations on coil embolisation of unruptured intracranial aneurysms. This involves placing coils inside the aneurysm using a thin tube to make the blood clot so it is less likely to burst.

Result type

HealthTech guidance

Published

26 January 2005

In development Reference number: GID-HTE10067 Expected publication date:  20 May 2026

Result type

Health technology evaluations

Status

In development

Evidence-based recommendations on irreversible electroporation (IRE) for treating renal cancer. This involves using electrical pulses to kill cancer cells, applied directly to the tumour through special needles.

Result type

HealthTech guidance

Published

23 February 2013

Evidence-based recommendations on thrombin injections for pseudoaneurysms. This involves injecting thrombin into the pseudoaneurysm. The aim is to form a small clot to plug the ‘hole’ in the artery.

Result type

HealthTech guidance

Published

27 May 2004

Evidence-based recommendations on percutaneous thrombectomy for intermediate-risk or high-risk pulmonary embolism. This involves removing the clot through a catheter inserted into a vein.

Result type

HealthTech guidance

Published

29 November 2023

ID NG41/1 Question Neuropathic pain relief:- Does early treatment with a centrally acting analgesic (for example pregabalin) reduce the...

Result type

Research recommendation

Published

4 April 2016

Evidence-based recommendations on ultrasound-guided percutaneous radiofrequency ablation for treating benign thyroid nodules in adults. This involves using heat energy to destroy tissue in the nodules.

Result type

HealthTech guidance

Published

22 June 2016

Evidence-based recommendations on trabeculotomy ab interno for open angle glaucoma. This involves using a specifically designed surgical instrument to remove a portion of tissue, with the aim of improving the eye’s drainage pathway.

Result type

HealthTech guidance

Published

25 May 2011

This indicator covers the contractor establishing and maintaining a register of patients aged 18 or over receiving drug treatment for epilepsy. It measures outcomes that reflect the quality of care or processes linked by evidence to improved outcomes. This indicator was previously published as NM237

Result type

General practice indicators suitable for use in QOF

Published

19 August 2023

Evidence-based recommendations on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia in adults. This involves electrically stimulating nerves in the throat or neck, while the person swallows. The aim is to strengthen the muscles involved in swallowing.

Result type

HealthTech guidance

Published

19 December 2018

Evidence-based recommendations on preoperative high dose rate brachytherapy for rectal cancers. This involves inserting an applicator into the rectum and using it to deliver radiation to the tumour.

Result type

HealthTech guidance

Published

26 August 2015

Evidence-based recommendations on percutaneous transluminal renal sympathetic denervation for resistant hypertension. This involves inserting a device through the skin (percutaneous) into an artery in the thigh and then into the renal arteries (transluminal). It sends radio or sound waves to destroy the nerves in the renal arteries (sympathetic denervation). The aim is to lower blood pressure.

Result type

HealthTech guidance

Published

1 March 2023

Evidence-based recommendations on selective internal radiation therapy for neuroendocrine tumours that have metastasised to the liver. This involves injecting tiny radioactive spheres into the blood vessels that supply the liver metastases.

Result type

HealthTech guidance

Published

16 May 2024

Evidence-based recommendations on high-intensity focused ultrasound for symptomatic breast fibroadenoma in adults. This involves using high-frequency sound waves to heat up the tissues in the lump.

Result type

HealthTech guidance

Published

13 September 2017

first-line therapies in primary care, or in the treatment of people with IBS that is refractory to other treatments? Any...

Result type

Research recommendation

Published

9 June 2015

Evidence-based recommendations on SeHCAT (tauroselcholic [75 selenium] acid) for diagnosing bile acid diarrhoea.

Result type

HealthTech guidance

Published

17 November 2021

This guideline covers diagnosing and managing drug allergy in all age groups. It aims to make it easier for professionals to tell when someone is having an allergic reaction, by specifying the key signs and patterns to look out for. It also makes recommendations on improving people’s understanding of their drug allergies, and ensuring these are recorded properly in their medical records.

Result type

Clinical guideline

Published

3 September 2014

Evidence-based recommendations on cryotherapy for chronic rhinitis. This involves destroying a nerve in the nose to reduce chronic rhinitis symptoms.

Result type

HealthTech guidance

Published

14 September 2023

This indicator covers rates of hysterectomy. It measures outcomes that reflect the quality of care or processes linked by evidence to improved outcomes. This indicator was previously published as CCG77

Result type

Network / system level indicators

Last updated

22 March 2024

In development Reference number: GID-HTE10065 Expected publication date:  02 April 2026

Result type

Health technology evaluations

Status

In development

syndrome and the number who have eculizumab, and the dose and duration of treatment - a national protocol for starting and stopping...

Result type

Research recommendation

Published

9 June 2015

Evidence-based recommendations on moorLDI2-BI: a laser doppler blood flow imager for burn wound assessment.

Result type

HealthTech guidance

Last updated

7 August 2017

duration of endoscopic follow-up for patients who have received endoscopic treatment for Barrett's oesophagus with dysplasia? Any...

Result type

Research recommendation

Published

9 March 2023

Evidence-based recommendations on endoscopic ablation for an anal fistula in adults. This involves applying heat to the fistula.

Result type

HealthTech guidance

Published

17 April 2019

Recommendation ID CG165/4 Question Prophylactic treatment in people receiving immunosuppressive therapy:- Further research should be...

Result type

Research recommendation

Published

9 June 2015

Recommendation ID NG83/1 Question Radical treatment of squamous cell carcinoma of the oesophagus:- Does the addition of surgery to...

Result type

Research recommendation

Published

13 November 2018

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for native aortic valve regurgitation. This involves implanting a replacement valve inside the faulty native valve.

Result type

HealthTech guidance

Published

24 June 2025

Question What is the clinical and cost effectiveness, post treatment and at longer-term follow‑up, of behavioural activation compared...

Result type

Research recommendation

Published

25 October 2019

Evidence-based recommendations on liposuction for chronic lymphoedema in adults. This involves using suction to remove fluid and fat through punctures in the skin.

Result type

HealthTech guidance

Published

27 April 2022

Evidence-based recommendations on electrochemotherapy for metastases in the skin from tumours of non-skin origin and melanoma. This involves applying short, powerful pulses of electricity to the tumour, allowing an anticancer drug to pass through into the cells.

Result type

HealthTech guidance

Published

27 March 2013

Evidence-based recommendations on selective internal radiation therapy for unresectable colorectal metastases in the liver in adults. This involves injecting beads that emit radiation directly into the tumour.

Result type

HealthTech guidance

Published

4 March 2020

Evidence-based recommendations on injectable bulking agents for faecal incontinence. This involves injecting a material into the muscles around the anus to bulk the sides of the sphincter.

Result type

HealthTech guidance

Published

28 February 2007

Evidence-based recommendations on liposuction for chronic lipoedema in adults. This involves using suction to remove abnormal fat.

Result type

HealthTech guidance

Published

29 March 2022

Evidence-based recommendations on CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack.

Result type

HealthTech guidance

Published

31 July 2024

or inflammatory exacerbation of proctitis that is resistant to standard treatment, what is the effectiveness of topical...

Result type

Research recommendation

Published

25 October 2019

Evidence-based recommendations on extracorporeal shockwave therapy for refractory plantar fasciitis. This involves using a machine to deliver sound waves to the painful area, with the aim to stimulate healing of the fascia.

Result type

HealthTech guidance

Published

26 August 2009

This document describes a real-world evidence framework that aims to improve the quality of real-world evidence informing our guidance. The framework does not set minimum standards for the acceptability of evidence. The framework is mainly targeted at those developing evidence to inform NICE guidance. It is also relevant to patients, those collecting data, and reviewers of evidence

How voluntary and community sector (VCS) organisations can help NICE develop guidance

How voluntary and community sector (VCS) organisations can help NICE develop guidance

Evidence-based recommendations on palliative photodynamic therapy for treating advanced oesophageal cancer. This involves injecting a photosensitising agent into the tumour and using light to activate it and destroy the tumour cells.

Result type

HealthTech guidance

Published

24 January 2007

In development Reference number: GID-TA11203 Expected publication date:  08 April 2026

Result type

Technology appraisal guidance

Status

In development

Evidence-based recommendations on photodynamic therapy for early-stage oesophageal cancer. This involves injecting a photosensitising agent into the tumour which is then activated by a light to destroy the tumour cells.

Result type

HealthTech guidance

Published

13 December 2006

Evidence-based recommendations on transvaginal laser therapy for urogenital atrophy. This involves using a laser in the vagina to increase its strength and elasticity, to improve symptoms of urogenital atrophy.

Result type

HealthTech guidance

Published

26 May 2021

Evidence-based recommendations on endoscopic radiofrequency therapy of the anal sphincter for faecal incontinence. This involves applying radiofrequency energy to the anal wall, with the aim of inducing muscle changes to improve muscle tone and help control bowel movement.

Result type

HealthTech guidance

Published

25 May 2011

duration of endoscopic follow-up for patients who have received endoscopic treatment for stage 1 oesophageal adenocarcinoma? Any...

Result type

Research recommendation

Published

9 March 2023

Evidence-based recommendations on percutaneous deep venous arterialisation for chronic limb-threatening ischaemia. This involves making a hole between a blocked artery and a vein, allowing the blood to flow into the leg beyond the blockage.

Result type

HealthTech guidance

Published

18 October 2023

Evidence-based recommendations on epiduroscopic lumbar discectomy through the sacral hiatus for sciatica in adults. This involves removing the part of the spinal disc pressing against the spinal nerve, to relieve pain.

Result type

HealthTech guidance

Published

14 December 2016

Evidence-based recommendations on percutaneous ultrasound-guided microwave ablation for symptomatic benign thyroid nodules. This involves using microwaves from a wire inserted into the nodule to heat and destroy it (ablation).

Result type

HealthTech guidance

Published

16 November 2022