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symptoms relevant to axial spondyloarthritis, X-ray, MRI and HLA-B27 test). All participants would be given a reference-standard...

Result type

Research recommendation

Published

4 May 2017

return to work and work retention are included in all the research they fund. This will ensure that all intervention...

Result type

Research recommendation

Published

5 October 2015

Evidence-based recommendations on photodynamic therapy for early-stage oesophageal cancer. This involves injecting a photosensitising agent into the tumour which is then activated by a light to destroy the tumour cells.

Result type

HealthTech guidance

Published

13 December 2006

Evidence-based recommendations on laparoscopic prostatectomy for benign prostatic obstruction. This involves removing the prostate through small cuts in the abdomen, using a fine telescope to see inside the body (keyhole surgery).

Result type

HealthTech guidance

Published

26 November 2008

NICE has developed a medtech innovation briefing (MIB) on Boston Keratoprosthesis Type I for corneal blindness .

Result type

Medtech innovation briefing

Published

18 January 2017

Evidence-based recommendations on percutaneous insertion of a closure device to repair a paravalvular leak around a replaced mitral or aortic valve. This involves passing a closure device through a catheter to block the area that is leaking.

Result type

HealthTech guidance

Published

23 June 2021

NICE has a developed medtech innovation briefing on Mollii suit for spasticity .

Result type

Medtech innovation briefing

Published

28 March 2017

NICE has developed a medtech innovation briefing (MIB) on Dexcom G6 for real-time continuous glucose monitoring .

Result type

Medtech innovation briefing

Published

3 November 2020

Evidence-based recommendations on breast reconstruction using lipomodelling after breast cancer treatment. This involves taking fat from the abdomen or thighs and injecting it into the breast in the area of the deformity caused by surgery.

Result type

HealthTech guidance

Published

23 January 2012

Evidence-based recommendations on cryotherapy for the treatment of liver metastases. This involves using cold temperatures applied through a special needle to destroy the cancer cells.

Result type

HealthTech guidance

Published

15 December 2010

Evidence-based recommendations on electrocautery cutting balloon treatment for pelviureteric junction obstruction. This involves widening the renal pelvis by inserting a catheter with a balloon and wire into the urinary tract.

Result type

HealthTech guidance

Published

16 December 2009

Evidence-based recommendations on placement of pectus bar for pectus excavatum (Nuss procedure). This involves placing one or two steel (pectus) bars under the breastbone with the aim of raising it and correcting the abnormal shape.

Result type

HealthTech guidance

Published

26 August 2009

Evidence-based recommendations on autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy. This involves removing parts of the pancreas (islet cells) after the pancreas has been removed and inserting them into the liver to restart insulin production.

Result type

HealthTech guidance

Published

24 September 2008

Evidence-based recommendations on brachytherapy as the sole method of adjuvant radiotherapy for breast cancer after local excision. This involves inserting radioactive sources into the space in the breast where tissue has been removed to minimise the chances of the cancer coming back.

Result type

HealthTech guidance

Published

23 July 2008

Evidence-based recommendations on therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injury. This involves cooling either the baby's head or whole body to prevent brain damage.

Result type

HealthTech guidance

Published

26 May 2010

Evidence-based recommendations on limited macular translocation for wet age related macular degeneration. This involves cutting and moving the macula on an a nearby healthier area of the retina.

Result type

HealthTech guidance

Published

19 May 2010

Evidence-based recommendations on percutaneous intradiscal laser ablation in the lumbar spine. This involves using a laser to destroy part of the disc, with the aim of shrinking it.

Result type

HealthTech guidance

Published

22 September 2010

NICE makes 4 types of recommendation that allow us to produce clear, directive, actionable guidance that is easy to understand and put into practice.

Guide for lay members who we've invited to sit on one of NICE's committees, panels, or groups.

Guide for lay members who we've invited to sit on one of NICE's committees, panels, or groups.

Evidence-based recommendations on obinutuzumab (Gazyvaro) for untreated advanced follicular lymphoma in adults.

Result type

Technology appraisal guidance

Published

21 March 2018

Evidence-based recommendations on teclistamab (Tecvayli) for relapsed and refractory multiple myeloma after 3 or more treatments in adults.

Result type

Technology appraisal guidance

Published

13 November 2024

Evidence-based recommendations on glofitamab (Columvi) plus gemcitabine and oxaliplatin for treating relapsed or refractory diffuse large B-cell lymphoma not otherwise specified in adults.

Result type

Technology appraisal guidance

Published

3 December 2025

Evidence-based recommendations on everolimus (Certican) for preventing organ rejection in adults having a liver transplant.

Result type

Technology appraisal guidance

Published

22 July 2015

Evidence-based recommendations on polatuzumab vedotin (Polivy) with rituximab and bendamustine for treating relapsed or refractory diffuse large B-cell lymphoma in adults who cannot have a haematopoietic stem cell transplant.

Result type

Technology appraisal guidance

Published

23 September 2020

Evidence-based recommendations on erythropoiesis-stimulating agents (epoetin alfa [Eprex], epoetin beta [NeoRecormon], epoetin theta, epoeitin zeta [Retacrit] and darbepoetin alfa [Aranesp]) for treating anaemia in adults with cancer having chemotherapy.

Result type

Technology appraisal guidance

Published

26 November 2014

Evidence-based recommendations on ruxolitinib (Jakavi). This drug is for adults with disease-related splenomegaly or symptoms caused by primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis, only if they have intermediate-2 or high-risk disease.

Result type

Technology appraisal guidance

Published

23 March 2016

agreed that there was not enough evidence to recommend sutures over staples in all surgery, and decided to focus the recommendation on...

Result type

Research recommendation

Published

16 August 2019

Any explanatory notes(if applicable) Why this is important:- Half of all traumatic spinal cord injuries involve the cervical spinal...

Result type

Research recommendation

Published

4 April 2016

Evidence-based recommendations on bendamustine for treating chronic lymphocytic leukaemia in adults.

Result type

Technology appraisal guidance

Published

23 February 2011

This quality standard covers the clinical assessment and management of depression in adults aged 18 and over. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Last updated

29 June 2023

This guideline covers diagnosing and managing pancreatic cancer in adults aged 18 and over. It aims to improve care by ensuring quicker and more accurate diagnosis, and by specifying the most effective treatments for people depending on how advanced their cancer is.

Result type

NICE guideline

Published

7 February 2018

Evidence-based recommendations on moorLDI2-BI: a laser doppler blood flow imager for burn wound assessment.

Result type

HealthTech guidance

Last updated

7 August 2017

Evidence-based recommendations on fetal vesico–amniotic shunt for lower urinary tract outflow obstruction. This involves inserting a cannula through the mother's abdominal and uterine walls into the amniotic cavity and subsequently into the bladder of the fetus.

Result type

HealthTech guidance

Published

13 December 2006

Evidence-based recommendations on combined endoscopic and laparoscopic removal of colonic polyps. This involves using an endoscope in the bowel plus keyhole surgery through the skin of the abdomen to remove colonic polyps.

Result type

HealthTech guidance

Published

26 September 2014

Embed NICE content in your digital products and services with our syndication API.

Evidence-based recommendations on hand transplant surgery (allotransplantation). This involves transplanting a hand from a recently deceased donor onto the amputated stump.

Result type

HealthTech guidance

Published

23 March 2011

Evidence-based recommendations on percutaneous closure of patent foramen ovale for the secondary prevention of recurrent paradoxical embolism in divers. This involves passing a device through a large vessel in the groin up into the heart and closing/blocking the hole in the wall.

Result type

HealthTech guidance

Published

15 December 2010

Evidence-based recommendations on laser-assisted cerebral vascular anastomosis without temporary arterial occlusion. This involves using a special laser device to create a bypass without the need to temporarily interrupt the blood flow to the brain.

Result type

HealthTech guidance

Published

27 February 2008

Evidence-based recommendations on Axonics sacral neuromodulation system for treating refractory overactive bladder.

Result type

HealthTech guidance

Published

3 September 2020

Clarification on demonstrating patient access to medicines and treatments recommended by NICE Technology Appraisal (TA) or Highly Specialised Technologies (HST) guidance.

Evidence-based recommendations on 12 standard quality house dust mite sublingual lyophilisate (SQ-HDM SLIT; Acarizax) for treating allergic rhinitis and allergic asthma caused by house dust mites.

Result type

Technology appraisal guidance

Published

5 March 2025

C: standard care placebo O: effectiveness outcomes: all-cause hospitalisation all-cause mortality need for mechanical...

Result type

Research recommendation

Published

14 July 2022

NICE has developed a medtech innovation briefing (MIB) on superDimension Navigation System to help diagnostic sampling of peripheral lung lesions .

Result type

Medtech innovation briefing

Published

11 October 2019

evidence suggests it is not cost effective to increase uptake of vaccination in all carers. Better understanding is needed about the...

Result type

Research recommendation

Published

12 December 2018

prevent hypoglycaemia. A blanket prescription of 5 or 10% glucose solution for all may result in hyperglycaemia in some children and...

Result type

Research recommendation

Published

28 January 2016

Evidence-based recommendations on docetaxel for treating hormone-refractory metastatic prostate cancer in adults.

Result type

Technology appraisal guidance

Published

28 June 2006

However, not all neonatal units have the facilities to carry out minimally invasive surfactant administration techniques, and not...

Result type

Research recommendation

Published

16 August 2019

consent and audit. Any explanatory notes(if applicable) Details of all patients should be entered into the UK TAVI registry....

Result type

Research recommendation

Published

22 June 2023

Early value assessment (EVA) guidance on digital technologies for delivering multidisciplinary weight-management services.

Result type

HealthTech guidance

Last updated

6 March 2024