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Showing 2501 to 2550 of 4138 results for patient

  1. AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas (MIB294)

    NICE has developed a medtech innovation briefing (MIB) on AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas .

    Medtech innovation briefing
    Published
    5 May 2022

  2. Anaesthesia: What is the clinical and cost effectiveness of regional versus general anaesthesia on postoperative morbidity in people with hip fracture?

    does not reflect current practice. In addition, in most of the studies the patients are sedated before regional anaesthesia is...

    Research recommendation
    Published
    3 February 2023

  3. Aortic valve reconstruction with glutaraldehyde-treated autologous pericardium for aortic valve disease (IPG769)

    Evidence-based recommendations on aortic valve reconstruction with glutaraldehyde-treated autologous pericardium for aortic valve disease in adults. This involves replacing the diseased part of the valve with some of the person’s own pericardium.

    Interventional procedures guidance
    Published
    9 August 2023
    View recommendations

    Sections for IPG769

  4. Transurethral water-jet ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia (IPG770)

    Evidence-based recommendations on transurethral water-jet ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia. This involves injecting a high-speed jet of water into the prostate to destroy some of the prostate tissue and widen the urethra.

    Interventional procedures guidance
    Published
    14 September 2023
    View recommendations

    Sections for IPG770

  5. Risk of systemic anticancer treatment in people with cancer and COVID-19: Are patients with cancer and COVID-19 who are receiving/have recently received systemic anticancer treatment (SACT) (that is, within the 4 weeks preceding a diagnosis of COVID-19) at increased risk of severe COVID-19 illness or death?

    of systemic anticancer treatment in people with cancer and COVID-19: Are patients with cancer and COVID-19 who are receiving/have...

    Research recommendation
    Published
    21 October 2021

  6. Photochemical corneal collagen cross‑linkage using riboflavin and ultraviolet A for keratoconus and keratectasia (IPG466)

    Evidence-based recommendations on photochemical corneal cross linkage using riboflavin and ultraviolet A for keratoconus. This involves using special eye drops and exposing the eye ultraviolet light, with the aim to strengthen the cornea.

    Interventional procedures guidance
    Published
    25 September 2013
    View recommendations

    Sections for IPG466

  7. Clostridioides difficile infection: antimicrobial prescribing (NG199)

    This guideline sets out an antimicrobial prescribing strategy for managing Clostridioides difficile infection in adults, young people and children aged 72 hours and over in community and hospital settings. It aims to optimise antibiotic use and reduce antibiotic resistance. The recommendations do not cover diagnosis.

    Antimicrobial prescribing guideline
    Published
    23 July 2021
    View recommendations

    Sections for NG199

  8. Pharmacological treatments for headache prophylaxis to aid withdrawal treatment in medication overuse headache:- Does a course of steroid treatment or pharmacological treatments used for headache prophylaxis help people with medication overuse headaches withdraw from medication?

    acute medication use, proportion of patients who no longer have suspected medication overuse headache, change in...

    Research recommendation
    Published
    9 June 2015

  9. Acne vulgaris: management (NG198)

    This guideline covers management of acne vulgaris in primary and specialist care. It includes advice on topical and oral treatments (including antibiotics and retinoids), treatment using physical modalities, and the impact of acne vulgaris on mental health and wellbeing.

    NICE guideline
    Last updated
    7 December 2023
    View recommendations

    Sections for NG198

  10. NICE also considered the role of FeNO measurement in asthma management. It accepted that currently available evidence on the use of FeNO measurement in asthma management is unclear on whether benefits of treatment are maintained long-term. NICE concluded that long-term studies following patients for several years could address this gap.

    are maintained long-term. NICE concluded that long-term studies following patients for several years could address this gap. Any...

    Research recommendation
    Published
    9 June 2015

  11. Developing NICE guidelines: the manual (PMG20)

    This manual explains the processes and methods used to develop and update NICE guidelines, the guidance that NICE develops covering topics across clinical care (in primary, secondary and community care settings), social care and public health. For more information on the other types of NICE guidance and advice (including technology appraisal guidance), see about NICE

  12. Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe emphysema is inadequate in quantity and quality. Therefore the procedure should only be used in the context of  research .

    evaluate safety and efficacy in the short and long term and include details of patient selection. NICE may update the guidance on...

    Research recommendation
    Published
    15 November 2019

  13. Percutaneous transluminal renal sympathetic denervation for resistant hypertension should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    controlled trials or analysis of registry data. It should report details of patient selection, technique used and long-term outcomes....

    Research recommendation
    Published
    27 April 2023

  14. Antimicrobial prescribing: delafloxacin for community-acquired pneumonia (ES37)

    Summary of the evidence on delafloxacin for community-acquired pneumonia in adults

    Evidence summary
    Published
    10 August 2021

  15. For people with favourable aneurysm morphology needing an EVAR as a primary procedure, evidence on the safety of using endoanchoring systems is adequate. However, evidence on efficacy is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should report details of patient selection and include longerterm outcomes. Source...

    Research recommendation
    Published
    1 June 2022

  16. For people with mild or moderate tricuspid regurgitation, evidence on the safety and efficacy of transcatheter tricuspid valve annuloplasty is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    4 August 2022

  17. For people with mild or moderate tricuspid regurgitation, evidence on the safety and efficacy of transcatheter tricuspid valve leaflet repair is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    5 August 2022

  18. Further research is needed to understand the effect of having the additional information provided by the adjunctive colposcopy technologies on anxiety for people having a colposcopy, when this information is shown to a person during the examination.

    that the adjunctive colposcopy technologies had the potential to improve patient experience and reduce anxiety (see section 5.8). Source...

    Research recommendation
    Published
    21 November 2018

  19. Drug-eluting stents for treating coronary artery disease: late-stage assessment (HTG747)

    Late-stage assessment (LSA) guidance on drug-eluting stents for treating coronary artery disease.

    HealthTech guidance
    Published
    6 May 2025
    View recommendations

    Sections for HTG747

  20. Evidence on the safety and efficacy of radiofrequency ablation for palliation of painful spinal metastases is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    encourages further research into the procedure. This should report details of patient selection, type of tumour and interventional...

    Research recommendation
    Published
    5 May 2023

  21. Middle meningeal artery embolisation for chronic subdural haematomas should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    trials or other suitably designed studies. It should report details of patient selection, technique used, rebleeding, functional...

    Research recommendation
    Published
    3 May 2024

  22. Information for family members or carers: What information and support are needed by family members or carers of people having treatment with an opioid, benzodiazepine, Z‑drug, antidepressant or gabapentinoid?

    of the evidence and the committee's discussion are in evidence review A: patient information and support. Source guidance details Comes...

    Research recommendation
    Published
    11 May 2022

  23. Donor milk banks: service operation (CG93)

    This guideline covers how donor milk banks should recruit, screen and support women who donate breast milk. It also covers how milk banks should handle and process the breast milk they receive from donors. It aims to improve the safety of donor milk and operation of donor milk services.

    Clinical guideline
    Published
    24 February 2010
    View recommendations

    Sections for CG93

  24. Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising primary care compared with usual care for people with multimorbidity?

    primary care for people with multimorbidity would be of value in defined patient groups (for example, people with multimorbidity who...

    Research recommendation
    Published
    18 October 2016

  25. Does a multidisciplinary team agreed approach to weaning from continuous positive airway pressure improve weaning times and result in stopping continuous positive airway pressure for people with COVID-19 and acute respiratory failure?

    weaning C: • standard care• different multidisciplinary team approaches O:• patient experience• symptom improvement• length of time to...

    Research recommendation
    Published
    12 November 2021

  26. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve annuloplasty is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    4 August 2022

  27. Information needs for children and young people:- during their care pathway to diagnosis of food allergy:- What do children and young people with IgE-mediated food allergy and their parents or carers want to know during the process of diagnosis and how is this demand best met?

    Any explanatory notes(if applicable) Why this is important:- The patient journey to diagnosis, through testing, can last for several...

    Research recommendation
    Published
    9 June 2015

  28. DOAC Dipstick for detecting direct oral anticoagulants (MIB248)

    NICE has developed a medtech innovation briefing (MIB) on DOAC Dipstick for detecting direct oral anticoagulants .

    Medtech innovation briefing
    Published
    2 February 2021

  29. Causes of unwitnessed falls among older inpatients:- What are the causes of unwitnessed falls among older inpatients?

    unwitnessed. Although staff may deduce reasons for the fall and/or the patient (if able and if asked) may describe their own perception...

    Research recommendation
    Published
    9 June 2015

  30. Evidence on the safety of repetitive short-pulse transscleral cyclophotocoagulation for glaucoma shows no major safety concerns. Evidence on efficacy is inadequate in quality. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE website.

    comparing the procedure with standard care. It should report details of patient selection, particularly whether the glaucoma is...

    Research recommendation
    Published
    16 August 2021

  31. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve leaflet repair is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    5 August 2022

  32. For people with unfavourable aneurysm morphology needing an endovascular aortic aneurysm repair (EVAR) as a primary procedure, or for people with an existing EVAR who need a secondary procedure, evidence on the safety of using endoanchoring systems is adequate. Evidence on efficacy is limited in quantity and quality. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should report details of patient selection and include longerterm outcomes. Source...

    Research recommendation
    Published
    1 June 2022

  33. Evidence on the safety and efficacy of supercapsular percutaneously assisted total hip arthroplasty for osteoarthritis is limited in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    standard approaches to total hip arthroplasty. It should report details of patient selection, short-term outcomes and long-term...

    Research recommendation
    Published
    1 June 2022

  34. Evidence on the safety of ab interno canaloplasty for open-angle glaucoma shows no major safety concerns. Evidence on the efficacy is limited in quality and quantity, particularly in the long term. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    notes(if applicable) Further research should report: - details of patient selection, including concurrent procedures, severity of...

    Research recommendation
    Published
    12 December 2022

  35. Evidence on the safety and efficacy of percutaneous thoracic duct embolisation for persistent chyle leak is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    embolisation for persistent chyle leak. Research should include details of patient selection, size and position of the leak, approaches...

    Research recommendation
    Published
    5 May 2023

  36. Complicated urinary tract infections: ceftolozane/tazobactam (ESNM74)

    Summary of the evidence on ceftolozane/tazobactam for treating complicated urinary tract infections to inform local NHS planning and decision-making

    Evidence summary
    Published
    9 June 2016

  37. Evidence on the safety of focal therapy using high-intensity focused ultrasound for localised prostate cancer is adequate, but evidence on its efficacy is limited. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    include registry data or randomised trials. It should include details of patient selection, including size and classification of tumour,...

    Research recommendation
    Published
    5 May 2023

  38. Evidence on the safety and efficacy of YAG laser vitreolysis for symptomatic vitreous floaters is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    powered randomised controlled trials. Research should report details of patient selection (including type, size and location of...

    Research recommendation
    Published
    7 November 2022

  39. Evidence on the safety and efficacy of permanent His-bundle pacemaker implantation for treating heart failure is inadequate in quality and quantity.Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    randomised controlled trials or registry data. It should report details of patient selection. Outcomes should include quality of life...

    Research recommendation
    Published
    10 August 2021

  40. Evidence on the safety of pressurised intraperitoneal aerosol chemotherapy for peritoneal carcinomatosis shows that this procedure can cause serious but well-recognised side effects. Evidence on its efficacy is inadequate in quality. Therefore, this procedure should only be used in the context of research. Find out what  only in research means on the NICE website .

    aerosol chemotherapy with standard care. Studies should report details of patient selection including type of tumour, the chemotherapy...

    Research recommendation
    Published
    22 January 2021

  41. Naldemedine for treating opioid-induced constipation (TA651)

    Evidence-based recommendations on naldemedine (Rizmoic) for treating opioid-induced constipation in adults who have had laxative treatment.

    Technology appraisal guidance
    Published
    30 September 2020
    View recommendations

    Sections for TA651

  42. BladderScan BVI 9400 3D portable ultrasound scanner for measuring bladder volume (MIB50)

    NICE has developed a medtech innovation briefing (MIB) on the BladderScan BVI 9400 3D portable ultrasound scanner for measuring bladder volume

    Medtech innovation briefing
    Published
    22 January 2016

  43. Multiple sclerosis in adults: management (NG220)

    This guideline covers diagnosing and managing multiple sclerosis in people aged 18 and over. It aims to improve the quality of life for people with multiple sclerosis by promoting prompt and effective symptom management and relapse treatment, and comprehensive reviews.

    NICE guideline
    Published
    22 June 2022
    View recommendations

    Sections for NG220

  44. Holistic assessment in the community:- What is the clinical and cost effectiveness of a community holistic assessment and intervention for people living with high levels of multimorbidity?

    intervention in people with multimorbidity would be of value in defined patient groups in the community (for example, people in nursing...

    Research recommendation
    Published
    18 October 2016

  45. Current evidence on the safety and efficacy of endovascular insertion of an intrasaccular wire-mesh blood-flow disruption device for intracranial aneurysms is adequate to support the use of this procedure provided that  standard arrangements   are in place for clinical governance, consent and audit.

    governance, consent and audit. Any explanatory notes(if applicable) Patient selection should be done by a multidisciplinary team, except...

    Research recommendation
    Published
    15 November 2019

  46. High-sensitivity troponin tests for the early rule out of NSTEMI (HTG552)

    Evidence-based recommendations on high-sensitivity troponin tests for the early rule out of NSTEMI (non-ST-segment elevation myocardial infarction).

    HealthTech guidance
    Published
    26 August 2020
    View recommendations

    Sections for HTG552

  47. Antenatal and postnatal mental health: clinical management and service guidance (CG192)

    This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year. It covers depression, anxiety disorders, eating disorders, drug- and alcohol-use disorders and severe mental illness (such as psychosis, bipolar disorder and schizophrenia). It promotes early detection and good management of mental health problems to improve women’s quality of life during pregnancy and in the year after giving birth.

    Clinical guideline
    Last updated
    11 February 2020
    View recommendations

    Sections for CG192

  48. Ectopic pregnancy and miscarriage: diagnosis and initial management (NG126)

    This guideline covers diagnosing and managing ectopic pregnancy and miscarriage in women with complications, such as pain and bleeding, in early pregnancy (that is, up to 13 completed weeks of pregnancy). It aims to improve how early pregnancy loss is diagnosed, and the support women are given, to limit the psychological impact of their loss.

    NICE guideline
    Last updated
    23 August 2023
    View recommendations

    Sections for NG126

  49. Research is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic or open surgery alongside general measures to reduce the risk of perioperative hypothermia (described in section 2.5). Research should report on the comparative rate of surgical site infections and other complications associated with hypothermia and normothermia, as well as related resource use.

    is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic or open surgery alongside general...

    Research recommendation
    Published
    26 April 2017

  50. Evidence on the safety and efficacy of daytime intraoral neuromuscular electrical tongue stimulation using a removable device for obstructive sleep apnoea is inadequate in quality and quantity. So, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    assess efficacy, safety and adherence. Research should report details of patient selection, duration of treatment and effect, effect on...

    Research recommendation
    Published
    5 May 2023