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Showing 2951 to 3000 of 3765 results for treatment

  1. Further research in superior rectal artery embolisation for haemorrhoids should report details of patient selection, and follow-up efficacy (including symptom relief), need for subsequent treatments, quality of life and safety outcomes for at least 1 year.

    and follow-up efficacy (including symptom relief), need for subsequent treatments, quality of life and safety outcomes for at least 1...

    Research recommendation
    Published
    12 December 2018

  2. Gefitinib for the second-line treatment of locally advanced or metastatic non-small-cell lung cancer (terminated appraisal) (TA175)

    This guidance has been updated and replaced by NICE technology appraisal guidance 374.

    Technology appraisal guidance
    Published
    22 July 2009

  3. Ixazomib citrate for maintenance treatment of untreated multiple myeloma in people who cannot have autologous stem cell transplant [ID2706]

    In development Reference number: GID-TA10589 Expected publication date: TBC

    Technology appraisal guidance
    In development

  4. Palbociclib with trastuzumab and endocrine therapy for maintenance treatment of hormone-receptor positive, HER2-positive metastatic breast cancer [ID6251]

    In development Reference number: GID-TA11273 Expected publication date: TBC

    Technology appraisal guidance
    In development

  5. Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection (TA761)

    This guidance has been updated and replaced by NICE technology appraisal guidance 1043.

    Technology appraisal guidance
    Published
    19 January 2022

  6. Flu vaccination: increasing uptake (NG103)

    This guideline covers how to increase uptake of the free flu vaccination among people who are eligible. It describes ways to increase awareness and how to use all opportunities in primary and secondary care to identify people who should be encouraged to have the vaccination.

    NICE guideline
    Published
    22 August 2018
    View recommendations

    Sections for NG103

  7. Surveillance strategies: How frequently should surveillance imaging be conducted, and which imaging modality should be used for people with stage IIB to IIIC melanoma?

    recommendation for research, see the rationale and section on follow-up after treatment for melanoma. Full details of the evidence and...

    Research recommendation
    Published
    4 August 2022

  8. Oesophagectomy: What is the effectiveness of endoscopic resection with or without adjuvant chemoradiotherapy and oesophagectomy for adults with T1b oesophageal adenocarcinoma?

    committee's discussion are in evidence review K: oesophagectomy versus endoscopy treatment. Source guidance details Comes from guidance...

    Research recommendation
    Published
    9 March 2023

  9. Impact of neonatal infection on the baby's family: What is the impact of neonatal infection on the health-related quality of life of the baby's family?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  10. Survivorship: What are the experiences of people who are living with, through and beyond a melanoma diagnosis in terms of survivorship and their disease journey?

    recommendation for research, see the rationale and section on follow-up after treatment for melanoma. Full details of the evidence and...

    Research recommendation
    Published
    4 August 2022

  11. Drug allergy (QS97)

    This quality standard covers diagnosing and managing drug allergy in adults, young people and children. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    30 July 2015
    View quality statements

    Sections for QS97

  12. Blood pressure targets for people aged over 80: What is the optimum blood pressure target for people aged over 80 with treated primary hypertension (with or without cardiovascular disease)?

    the committee's discussion are in the evidence review K: pharmacological treatment in cardiovascular disease . Source guidance details...

    Research recommendation
    Published
    11 April 2022

  13. What is the clinical and cost effectiveness of cognitive behavioural therapy (CBT) for adults with tinnitus delivered by appropriately trained healthcare professionals other than psychologists (for example, audiologists)?

    intervention. This intervention would allow people with tinnitus to receive their treatment faster and help to reduce waiting lists. It...

    Research recommendation
    Published
    17 March 2020

  14. What is the clinical and cost effectiveness of psychological therapies for children and young people who have tinnitus-related distress?

    intervention. This intervention would allow people with tinnitus to receive their treatment faster and help to reduce waiting lists. It...

    Research recommendation
    Published
    17 March 2020

  15. Risk factors for and clinical indicators of early-onset infection: What is the risk of early-onset neonatal infection with maternal obesity and how does this change with increasing body mass index?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  16. Emotional freedom techniques:- What is the clinical and cost effectiveness of emotional freedom techniques (EFT) for the treatment of PTSD in adults?

    clinical and cost effectiveness of emotional freedom techniques (EFT) for the treatment of PTSD in adults? Any explanatory notes(if...

    Research recommendation
    Published
    13 February 2019

  17. Endovascular stent insertion for intracranial atherosclerotic disease should only be used in the context of research. Research should clearly define patient selection and be designed to provide outcome data based on follow-up of at least 2 years.

    no substantial differences in clinical outcomes compared with medical treatment after 1–2 years. Evidence on its safety shows that there...

    Research recommendation
    Published
    9 June 2015

  18. Impact of drug-related adverse effects on cost effectiveness and quality of life:- What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic pain?

    about how this affects cost of the quality of life of patients receiving treatment. Further research should be conducted as described...

    Research recommendation
    Published
    9 June 2015

  19. Intravascular catheters for reducing the risk of late-onset neonatal infection: What is the effectiveness of catheters impregnated with silver zeolite for preventing late-onset catheter-related bloodstream infections in newborn babies?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  20. Bladder management strategies:- What are the long-term risks and effects on quality of life of different bladder management strategies for lower urinary tract dysfunction in people with neurological disease?

    other neurological diseases. Bladder management strategies are a long-term treatment with implications for maintaining health and...

    Research recommendation
    Published
    9 June 2015

  21. Living-donor lung transplantation for end-stage lung disease (IPG170)

    Evidence-based recommendations on living-donor lung transplantation for end-stage lung disease. This involves removing a lung from each of the two donors and replacing the recipient's lungs with the donor lungs.

    Interventional procedures guidance
    Published
    24 May 2006
    View recommendations

    Sections for IPG170

  22. Tests to help assess risk of acute kidney injury for people being considered for critical care admission (ARCHITECT and Alinity i Urine NGAL assays, BioPorto NGAL test and NephroCheck test) (HTG544)

    Evidence-based recommendations on tests to help assess risk of acute kidney injury for people being considered for critical care admission. The tests are the ARCHITECT and ALINITY i Urine NGAL assays, BioPorto NGAL test and NephroCheck test.

    HealthTech guidance
    Published
    17 June 2020
    View recommendations

    Sections for HTG544

  23. Medication choice in people with no previous medication for ADHD:- What is the clinical and cost effectiveness of ADHD medications in people with ADHD with noprevious medication for the condition?

    diagnosed ADHD.There may be differing levels of efficacy of the various treatment options in people who have received no previous...

    Research recommendation
    Published
    14 November 2018

  24. Specialist investigation:- What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H2 receptor antagonists (H2RAs) despite optimum primary care?

    correct diagnosis or to correct misdiagnosis, so that the most appropriate treatment can be offered. Source guidance details Comes from...

    Research recommendation
    Published
    9 June 2015

  25. Intravascular catheters for reducing the risk of late-onset neonatal infection: What is the effectiveness of antimicrobial-impregnated catheters other than those impregnated with rifampicin and miconazole for preventing late-onset catheter-related bloodstream infections in newborn babies?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  26. Risk factors for and clinical indicators of early-onset infection: What is the accuracy of clinical prediction models for early-onset neonatal infection in the UK and what is their effectiveness in guiding management in the baby?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  27. Fluocinolone acetonide intravitreal implant for the treatment of chronic diabetic macular oedema after an inadequate response to prior therapy (TA271)

    This guidance has been updated and replaced by NICE technology appraisal guidance 301.

    Technology appraisal guidance
    Published
    23 January 2013

  28. For people with generalised anxiety disorder (GAD) who are ready to start a low-intensity intervention, what is the clinical effectiveness of physical activity compared with waiting-list control?

    of this study will have important implications in widening the range of treatment options available in the NHS. Source guidance details...

    Research recommendation
    Published
    9 June 2015

  29. Interventions to improve CPAP adherence: Which interventions, including behavioural interventions, are most clinically and cost effective to improve adherence to CPAP in people with OSAHS, obesity hypoventilation syndrome (OHS) and COPD–OSAHS (chronic obstructive pulmonary disease–OSAHS) overlap syndrome who have difficulty using CPAP?

    recommendation for research, see the rationale section on supporting adherence to treatment for OSAHS. Full details of the evidence and...

    Research recommendation
    Published
    30 September 2021

  30. Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared with atypical antipsychotic drugs for treating psychotic symptoms (particularly hallucinations and delusions) associated with Parkinson's disease?

    to undertake primary research in this area to determine the most effective treatment options formanaging Parkinson's disease psychosis....

    Research recommendation
    Published
    15 October 2018

  31. Risk factors for and clinical indicators of late-onset infection: What is the accuracy of new or existing clinical prediction models for late-onset neonatal infection in the UK and what is their effectiveness in guiding management: - for babies already on a neonatal unit? - for babies admitted from home?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  32. What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H 2   receptor antagonists (H 2 RAs) despite optimum primary care?

    correct diagnosis or to correct misdiagnosis, so that the most appropriate treatment can be offered. Source guidance details Comes from...

    Research recommendation
    Published
    15 November 2019

  33. Pemetrexed maintenance treatment following induction therapy with pemetrexed and cisplatin for non-squamous non-small-cell lung cancer (TA309)

    This guidance has been updated and replaced by NICE technology appraisal guidance 402.

    Technology appraisal guidance
    Published
    23 April 2014

  34. Dostarlimab with docetaxel for treating advanced non-small-cell lung cancer after anti-PD-L1 treatment and chemotherapy [ID6530]

    Discontinued Reference number: GID-TA11655

    Technology appraisal guidance
    Discontinued

  35. Social work with adults experiencing complex needs (NG216)

    This guideline covers the planning, delivery and review of social work interventions for adults who have complex needs. It promotes ways for social work professionals, other care staff and people with complex needs to work together to make decisions about care and support.

    NICE guideline
    Published
    26 May 2022
    View recommendations

    Sections for NG216

  36. Changes to NICE's cost-effectiveness thresholds confirmed

    The government has today (1 December 2025) announced that it will increase the thresholds NICE uses in evaluations of new medicines to decide which are cost-effective for use in the NHS.

    News
    Last updated
    4 December 2025

  37. Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management for cystoid macular oedema?

    lead to the formulation offuture recommendations for the postoperative treatment cystoid macular oedema. Source guidance details Comes...

    Research recommendation
    Published
    18 October 2018

  38. Core outcome set for studies of management of Lyme disease:- Can a core outcome set be developed for clinical trials of management of Lyme disease?

    explanatory notes(if applicable) Why this is important:- Antibiotic treatment is the mainstay of management for Lyme disease. The...

    Research recommendation
    Published
    21 November 2018

  39. Dietitian contribution to patient management:- How can the role of the dietitian contribute most effectively within a coeliac disease team?

    applicable) Why this is important:- As a gluten-free diet is the primary treatment option for people with coeliac disease, it is...

    Research recommendation
    Published
    13 October 2015

  40. SecurAcath for securing percutaneous catheters (HTG440)

    Evidence-based recommendations on SecurAcath for securing percutaneous catheters.

    HealthTech guidance
    Last updated
    10 August 2022
    View recommendations

    Sections for HTG440

  41. Is the use of chlorhexidine body wash associated with increased antimicrobial resistance?

    An economic model based on UK data demonstrated that, compared with no treatment, using mupirocin with a chlorhexidine body wash before...

    Research recommendation
    Published
    16 August 2019

  42. Embryo selection for single embryo transfer:- Further research is needed to improve embryo selection to facilitate single embryo transfers.

    details Comes from guidance Fertility problems: assessment and treatment Number CG156 Date issued February 2013 Other

    Research recommendation
    Published
    9 June 2015

  43. Dedicated transfer service:- Is it clinically and cost effective to provide a dedicated service to transfer patients with major trauma from the emergency department for ongoing care?

    transfer them without delay but may not be able to provide specialist treatment during the transfer. A specialist team sent by the...

    Research recommendation
    Published
    4 April 2016

  44. Evidence on the safety and efficacy of daytime intraoral neuromuscular electrical tongue stimulation using a removable device for obstructive sleep apnoea is inadequate in quality and quantity. So, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    adherence. Research should report details of patient selection, duration of treatment and effect, effect on snoring and sleep apnoea,...

    Research recommendation
    Published
    5 May 2023

  45. In patients hospitalised with moderate- to high-severity community-acquired pneumonia, does using C-reactive protein monitoring in addition to clinical observation to guide antibiotic duration safely reduce the total duration of antibiotic therapy compared with a fixed empirical antibiotic course?

    by NICE. The burden of community-acquired pneumonia is large, and its treatment accounts for a high proportion of antibiotic use in...

    Research recommendation
    Published
    9 June 2015

  46. Is intravenous methylprednisolone more clinically and cost effective than oral methylprednisolone in people with relapsing–remitting Multiple Sclerosis (MS) and people with secondary progressive MS with continued relapses?

    which place a burden on individual patients and the NHS. The primary treatment of acute relapses is with corticosteroids, using a...

    Research recommendation
    Published
    9 June 2015

  47. The evidence on transvaginal laser therapy for urogenital atrophy does not show any short-term safety concerns. Evidence on long-term safety and efficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    randomised controlled trials and report details of patient selection, treatment protocols, and long-term safety and efficacy including...

    Research recommendation
    Published
    10 August 2021

  48. Further research is recommended on resource use and clinical effects associated with using the xTAG Gastrointestinal Pathogen Panel, the FilmArray GI Panel and the Faecal Pathogens B assay.

    to:- length of stay in hospital- length of time in isolation- change of treatment plan as a result of testing. Source guidance details...

    Research recommendation
    Published
    17 February 2017

  49. Pharmacological therapies:- What is the clinical and cost effectiveness of codeine with and without paracetamol for the acute management of low back pain?

    using paracetamol and codeine together has a synergistic effect in the treatment of back pain. Source guidance details Comes from...

    Research recommendation
    Published
    13 February 2017

  50. Monitoring for cystic-fibrosis-related diabetes:- What is the most effective strategy to detect diabetes in people with cystic fibrosis?

    identification of cystic-fibrosis-related diabetes would help teams start prompt treatment and prevent the clinical decline associated...

    Research recommendation
    Published
    18 October 2018