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Showing 3001 to 3050 of 3761 results for treatment

  1. Impact of neonatal infection on the baby's family: What is the impact of neonatal infection on the health-related quality of life of the baby's family?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  2. Survivorship: What are the experiences of people who are living with, through and beyond a melanoma diagnosis in terms of survivorship and their disease journey?

    recommendation for research, see the rationale and section on follow-up after treatment for melanoma. Full details of the evidence and...

    Research recommendation
    Published
    4 August 2022

  3. Favezelimab–pembrolizumab for treating relapsed or refractory classical Hodgkin lymphoma after anti-PD-L1 treatment [ID6393]

    In development Reference number: GID-TA11486 Expected publication date: TBC

    Technology appraisal guidance
    In development

  4. Olaparib plus bevacizumab for maintenance treatment of advanced ovarian, fallopian tube or primary peritoneal cancer (TA693)

    This guidance has been updated and replaced by NICE technology appraisal guidance 946.

    Withdrawn guidance

  5. Blood pressure targets for people aged over 80: What is the optimum blood pressure target for people aged over 80 with treated primary hypertension (with or without cardiovascular disease)?

    the committee's discussion are in the evidence review K: pharmacological treatment in cardiovascular disease . Source guidance details...

    Research recommendation
    Published
    11 April 2022

  6. Risk factors for and clinical indicators of early-onset infection: What is the risk of early-onset neonatal infection with maternal obesity and how does this change with increasing body mass index?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  7. Endoscopic augmentation of the lower oesophageal sphincter using hydrogel implants for the treatment of gastro-oesophageal reflux disease (IPG222)

    We have moved interventional procedures guidance 222 to become HealthTech guidance 142. This is to better reflect the NICE HealthTech programme which combines the former NICE Diagnostics Assessment programme, Interventional Procedures programme and Medical Technologies Evaluation programme and to help you find relevant content more quickly. The guidance itself has not changed.

    Withdrawn guidance

  8. Endovascular stent insertion for intracranial atherosclerotic disease should only be used in the context of research. Research should clearly define patient selection and be designed to provide outcome data based on follow-up of at least 2 years.

    no substantial differences in clinical outcomes compared with medical treatment after 1–2 years. Evidence on its safety shows that there...

    Research recommendation
    Published
    9 June 2015

  9. Impact of drug-related adverse effects on cost effectiveness and quality of life:- What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic pain?

    about how this affects cost of the quality of life of patients receiving treatment. Further research should be conducted as described...

    Research recommendation
    Published
    9 June 2015

  10. Intravascular catheters for reducing the risk of late-onset neonatal infection: What is the effectiveness of catheters impregnated with silver zeolite for preventing late-onset catheter-related bloodstream infections in newborn babies?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  11. Medication choice in people with no previous medication for ADHD:- What is the clinical and cost effectiveness of ADHD medications in people with ADHD with noprevious medication for the condition?

    diagnosed ADHD.There may be differing levels of efficacy of the various treatment options in people who have received no previous...

    Research recommendation
    Published
    14 November 2018

  12. Specialist investigation:- What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H2 receptor antagonists (H2RAs) despite optimum primary care?

    correct diagnosis or to correct misdiagnosis, so that the most appropriate treatment can be offered. Source guidance details Comes from...

    Research recommendation
    Published
    9 June 2015

  13. Intravascular catheters for reducing the risk of late-onset neonatal infection: What is the effectiveness of antimicrobial-impregnated catheters other than those impregnated with rifampicin and miconazole for preventing late-onset catheter-related bloodstream infections in newborn babies?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  14. Risk factors for and clinical indicators of early-onset infection: What is the accuracy of clinical prediction models for early-onset neonatal infection in the UK and what is their effectiveness in guiding management in the baby?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  15. For people with generalised anxiety disorder (GAD) who are ready to start a low-intensity intervention, what is the clinical effectiveness of physical activity compared with waiting-list control?

    of this study will have important implications in widening the range of treatment options available in the NHS. Source guidance details...

    Research recommendation
    Published
    9 June 2015

  16. Interventions to improve CPAP adherence: Which interventions, including behavioural interventions, are most clinically and cost effective to improve adherence to CPAP in people with OSAHS, obesity hypoventilation syndrome (OHS) and COPD–OSAHS (chronic obstructive pulmonary disease–OSAHS) overlap syndrome who have difficulty using CPAP?

    recommendation for research, see the rationale section on supporting adherence to treatment for OSAHS. Full details of the evidence and...

    Research recommendation
    Published
    30 September 2021

  17. Psychotic symptoms (hallucinations and delusions):- What is the effectiveness of rivastigmine compared with atypical antipsychotic drugs for treating psychotic symptoms (particularly hallucinations and delusions) associated with Parkinson's disease?

    to undertake primary research in this area to determine the most effective treatment options formanaging Parkinson's disease psychosis....

    Research recommendation
    Published
    15 October 2018

  18. Risk factors for and clinical indicators of late-onset infection: What is the accuracy of new or existing clinical prediction models for late-onset neonatal infection in the UK and what is their effectiveness in guiding management: - for babies already on a neonatal unit? - for babies admitted from home?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  19. What specialist investigations should be conducted to exclude a diagnosis of functional dyspepsia in people with uninvestigated dyspepsia that does not respond to PPIs or H 2   receptor antagonists (H 2 RAs) despite optimum primary care?

    correct diagnosis or to correct misdiagnosis, so that the most appropriate treatment can be offered. Source guidance details Comes from...

    Research recommendation
    Published
    15 November 2019

  20. Care and support of people growing older with learning disabilities (NG96)

    This guideline covers care and support for adults with learning disabilities as they grow older. It covers identifying changing needs, planning for the future, and delivering services including health, social care and housing. It aims to support people to access the services they need as they get older.

    NICE guideline
    Published
    11 April 2018
    View recommendations

    Sections for NG96

  21. Bladder management strategies:- What are the long-term risks and effects on quality of life of different bladder management strategies for lower urinary tract dysfunction in people with neurological disease?

    other neurological diseases. Bladder management strategies are a long-term treatment with implications for maintaining health and...

    Research recommendation
    Published
    9 June 2015

  22. Interventions to manage cystoid macular oedema:- What is the most effective postoperative medical management for cystoid macular oedema?

    lead to the formulation offuture recommendations for the postoperative treatment cystoid macular oedema. Source guidance details Comes...

    Research recommendation
    Published
    18 October 2018

  23. Core outcome set for studies of management of Lyme disease:- Can a core outcome set be developed for clinical trials of management of Lyme disease?

    explanatory notes(if applicable) Why this is important:- Antibiotic treatment is the mainstay of management for Lyme disease. The...

    Research recommendation
    Published
    21 November 2018

  24. Dietitian contribution to patient management:- How can the role of the dietitian contribute most effectively within a coeliac disease team?

    applicable) Why this is important:- As a gluten-free diet is the primary treatment option for people with coeliac disease, it is...

    Research recommendation
    Published
    13 October 2015

  25. Ipilimumab for the adjuvant treatment of completely resected stage IV or high risk stage III melanoma [ID721]

    Discontinued Reference number: GID-TAG479

    Technology appraisal guidance
    Discontinued

  26. Denosumab for the treatment of therapy-induced bone loss in non-metastatic prostate cancer (terminated appraisal) (TA194)

    This guidance has been updated and replaced by NICE guideline CG175.

    Withdrawn guidance

  27. Inhaler devices for routine treatment of chronic asthma in older children (aged 5 to 15 years) (TA38)

    This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).

    Withdrawn guidance

  28. What is the clinical and cost effectiveness of cognitive behavioural therapy (CBT) for adults with tinnitus delivered by appropriately trained healthcare professionals other than psychologists (for example, audiologists)?

    intervention. This intervention would allow people with tinnitus to receive their treatment faster and help to reduce waiting lists. It...

    Research recommendation
    Published
    17 March 2020

  29. What is the clinical and cost effectiveness of psychological therapies for children and young people who have tinnitus-related distress?

    intervention. This intervention would allow people with tinnitus to receive their treatment faster and help to reduce waiting lists. It...

    Research recommendation
    Published
    17 March 2020

  30. Embryo selection for single embryo transfer:- Further research is needed to improve embryo selection to facilitate single embryo transfers.

    details Comes from guidance Fertility problems: assessment and treatment Number CG156 Date issued February 2013 Other

    Research recommendation
    Published
    9 June 2015

  31. Dedicated transfer service:- Is it clinically and cost effective to provide a dedicated service to transfer patients with major trauma from the emergency department for ongoing care?

    transfer them without delay but may not be able to provide specialist treatment during the transfer. A specialist team sent by the...

    Research recommendation
    Published
    4 April 2016

  32. Evidence on the safety and efficacy of daytime intraoral neuromuscular electrical tongue stimulation using a removable device for obstructive sleep apnoea is inadequate in quality and quantity. So, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    adherence. Research should report details of patient selection, duration of treatment and effect, effect on snoring and sleep apnoea,...

    Research recommendation
    Published
    5 May 2023

  33. In patients hospitalised with moderate- to high-severity community-acquired pneumonia, does using C-reactive protein monitoring in addition to clinical observation to guide antibiotic duration safely reduce the total duration of antibiotic therapy compared with a fixed empirical antibiotic course?

    by NICE. The burden of community-acquired pneumonia is large, and its treatment accounts for a high proportion of antibiotic use in...

    Research recommendation
    Published
    9 June 2015

  34. Is intravenous methylprednisolone more clinically and cost effective than oral methylprednisolone in people with relapsing–remitting Multiple Sclerosis (MS) and people with secondary progressive MS with continued relapses?

    which place a burden on individual patients and the NHS. The primary treatment of acute relapses is with corticosteroids, using a...

    Research recommendation
    Published
    9 June 2015

  35. Gilteritinib for maintenance treatment of FLT3-mutation-positive acute myeloid leukaemia after stem cell transplant [ID6243]

    Discontinued Reference number: GID-TA11255

    Technology appraisal guidance
    Discontinued

  36. PeritX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites (MTG9)

    We have moved medical technologies guidance 9 to become HealthTech guidance 282. This is to better reflect the NICE HealthTech programme which combines the former NICE Diagnostics Assessment programme, Interventional Procedures programme and Medical Technologies Evaluation programme and to help you find relevant content more quickly. The guidance itself has not changed.

    Withdrawn guidance

  37. The evidence on transvaginal laser therapy for urogenital atrophy does not show any short-term safety concerns. Evidence on long-term safety and efficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    randomised controlled trials and report details of patient selection, treatment protocols, and long-term safety and efficacy including...

    Research recommendation
    Published
    10 August 2021

  38. Donor milk banks: service operation (CG93)

    This guideline covers how donor milk banks should recruit, screen and support women who donate breast milk. It also covers how milk banks should handle and process the breast milk they receive from donors. It aims to improve the safety of donor milk and operation of donor milk services.

    Clinical guideline
    Published
    24 February 2010
    View recommendations

    Sections for CG93

  39. Pharmacological therapies:- What is the clinical and cost effectiveness of codeine with and without paracetamol for the acute management of low back pain?

    using paracetamol and codeine together has a synergistic effect in the treatment of back pain. Source guidance details Comes from...

    Research recommendation
    Published
    13 February 2017

  40. Monitoring for cystic-fibrosis-related diabetes:- What is the most effective strategy to detect diabetes in people with cystic fibrosis?

    identification of cystic-fibrosis-related diabetes would help teams start prompt treatment and prevent the clinical decline associated...

    Research recommendation
    Published
    18 October 2018

  41. The evidence on transvaginal laser therapy for stress urinary incontinence does not show any short-term safety concerns. Evidence on long-term safety andefficacy is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means onthe NICE interventional procedures guidance page.

    long-term safety and efficacy outcomes, the type of laser and energy used, treatment protocols, and patient selection including age,...

    Research recommendation
    Published
    10 August 2021

  42. Autologous blood injection for plantar fasciitis (HTG298)

    Evidence-based recommendations on autologous blood injection for plantar fasciitis. This involves supplying the connective tissue with growth factors that promote the healing process.

    HealthTech guidance
    Published
    23 January 2013
    View recommendations

    Sections for HTG298

  43. Inhaled corticosteroids for the treatment of chronic asthma in adults and in children aged 12 years and over (TA138)

    This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).

    Withdrawn guidance

  44. Bisphosphonates for the prevention of bone disease:- What is the effectiveness of monthly zoledronic acid given indefinitely compared with zoledronic acid given for a fixed duration in patients with myeloma?

    in people with myeloma. However, the optimal frequency and duration of treatment is not clearly defined and needs further research,...

    Research recommendation
    Published
    5 April 2016

  45. What is the clinical effectiveness of double-dose PPIs in people with severe erosive reflux disease (Los Angeles classification grade C/D or Savary–Miller grade 3/4): to reduce severe oesophagitis to control symptoms as maintenance therapy?

    It would substantially improve people's quality of life if an optimal treatment regimen could be identified. Currently, there is a lack...

    Research recommendation
    Published
    15 November 2019

  46. What are the risks that predict the development of blood-borne virus infections in people with complex psychosis in the UK?

    in the UK? Any explanatory notes(if applicable) Care and treatment for physical health conditions (recommendations 1.10.18 and 1.10.19)...

    Research recommendation
    Published
    26 October 2020

  47. Clinical epidemiology of Lyme disease in the UK:- What are the incidence, presenting features, management and outcome of Lyme disease in the UK?

    stics. These statistics would enable interventions such as antibiotic treatment and service improvements to be assessed properly and for...

    Research recommendation
    Published
    21 November 2018

  48. What specialist management is effective for people whose symptoms do not respond to PPIs despite optimum primary care, or for people whose symptoms return after surgery?

    tricyclic antidepressants versus standard or full-dose PPI. The purpose of any treatment should focus on improving quality of life....

    Research recommendation
    Published
    15 November 2019

  49. HPV testing:- What is the comparative effectiveness of single-step laboratory diagnostic tests to identify human papillomavirus (HPV) against current diagnostic test algorithms and reference standards in people with cancer of the oropharynx?

    Current methods use a 2-step procedure that is not widely available in all treatment centres. A single-step test is likely to be more...

    Research recommendation
    Published
    6 April 2016

  50. Transvaginal mesh repair of anterior or posterior vaginal wall prolapse (HTG456)

    Evidence-based recommendations on transvaginal mesh repair of anterior or posterior vaginal wall prolapse. This involves inserting a mesh to replace tissue that has weakened and caused the pelvic organs to drop down (prolapse) into the vagina.

    HealthTech guidance
    Published
    15 December 2017
    View recommendations

    Sections for HTG456