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bone mineral density (BMD). Input of BMD into the questionnaire in such patients will therefore generate the same fracture risk whether...
there is little empirical evidence to guide healthcare professionals or patients in choosing which disorder should be treated first....
or more years. Neither FRAX nor QFracture has been examined in treated patients, and it is not known whether the ability of clinical...
Eteplirsen for treating Duchenne muscular dystrophy [ID1003]
Discontinued Reference number: GID-HST10007
fracture risk possible at the time of consultation. However, refinement of a patient's 10-year fracture risk using BMD requires...
NICE has developed a medtech innovation briefing (MIB) on Coban 2 for venous leg ulcers .
can progress to fibrosis, cirrhosis and hepatocellular cancer. In most patients NAFLD is asymptomatic and is only detected incidentally...
Methods for the development of NICE public health guidance (third edition) (PMG4)
This manual describes the methods used by the Centre for Public Health Excellence (CPHE) in NICE to develop and update public health guidance
medical patients in the UK have prophylaxis when the national tool has been used, with some trusts offering prophylaxis to over 90% of...
Fetal cystoscopy for the diagnosis and treatment of lower urinary outflow tract obstruction (HTG131)
Evidence-based recommendations on fetal cystoscopy for the diagnosis and treatment of lower urinary outflow tract obstruction. This involves inserting a tube with a flexible camera through small cuts in the mother's abdomen to identify and open any blockage.
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Sections for HTG131
Emapalumab for treating primary haemophagocytic lymphohistiocytosis (ID1438)
Discontinued Reference number: GID-TA10527
there is very sparse evidence about which strategies are most acceptable to patients and/or their family members and carers. The current...
generally remains for life. Current clinical experience suggests that most patients in a community setting who are believed to be...
Discontinued Reference number: GID-TA10072
Why this is important:- Multidisciplinary care improves survival in patients with MND. The evidence is drawn from models of...
Discontinued Reference number: GID-TA10310
Urinary tract infection (catheter-associated): antimicrobial prescribing (NG113)
This guideline sets out an antimicrobial prescribing strategy for catheter-associated urinary tract infection in children, young people and adults. It aims to optimise antibiotic use and reduce antibiotic resistance.
Vitamin D: supplement use in specific population groups (PH56)
This guideline covers vitamin D supplement use. It aims to prevent vitamin D deficiency among specific population groups including infants and children aged under 4, pregnant and breastfeeding women, particularly teenagers and young women, people over 65, people who have low or no exposure to the sun and people with dark skin.
of cirrhosis. Approximately half of patients with cirrhosis have oesophageal varices, and one-third of all patients with...
needs or incontinence and visual impairment are common in older hospital patients. Several multifactorial studies have included...
conditions are limited to small numbers of patients within case series studies that include heterogeneous groups of...
Framingham or Bonn veins studies, should be undertaken. The study should recruit patients with C2 and C3 disease and follow the progress...
treatment-related morbidity and mortality. In a very small percentage of patients with squamous carcinoma involving a cervical lymph...
that ambulatory oxygen therapy is effective in achieving these aims in patients with idiopathic pulmonary fibrosis. A randomised...
early intervention with systemic treatments alters prognosis. Consequently, patients with more severe disease sequence through all...
Transition between inpatient mental health settings and community or care home settings (NG53)
This guideline covers the period before, during and after a person is admitted to, and discharged from, a mental health hospital. It aims to help people who use mental health services, and their families and carers, to have a better experience of transition by improving the way it’s planned and carried out.
Evidence-based recommendations on septostomy with or without amnioreduction for treating twin-to-twin transfusion syndrome. This involves creating a small hole in the membrane between the babies to allow the amniotic fluid to move from one baby to the other, so both babies have a more equal amount of amniotic fluid.
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Sections for HTG127
dietary advice to address the common questions asked by newly diagnosed patients on preventing disease progression. However, although...
Perioperative Quality Improvement Programme (PQIP) 2017/2018 annual report, 61% of patients enrolled in the PQIP were following an ERP....
NICE has developed a medtech innovation briefing (MIB) on Accuro for guiding epidural or spinal anaesthesia .
Deferred tributary treatment may reduce morbidity, and also mean that some patients do not need tributary treatment (or need fewer...
Onasemnogene abeparvovec for treating presymptomatic spinal muscular atrophy (HST24)
Evidence-based recommendations on onasemnogene abeparvovec (Zolgensma) for treating presymptomatic spinal muscular atrophy in babies aged 12 months and under.
Evidence-based recommendations on cabotegravir (Vocabria) with rilpivirine (Rekambys) for treating HIV-1 in adults. This includes adults with virological suppression (HIV-1 RNA fewer than 50 copies/ml) on a stable antiretroviral regimen, and without any evidence of viral resistance to, and no previous virological failure with, any non-nucleoside reverse transcriptase inhibitors or integrase inhibitors.
This guideline covers road-traffic-related air pollution and its links to ill health. It aims to improve air quality and so prevent a range of health conditions and deaths.
Antimicrobial prescribing: oritavancin for acute bacterial skin and skin structure infections (ES39)
Summary of the evidence on oritavancin for acute bacterial skin and skin structure infections (ABSSSI) in adults
Faster, fairer access to HealthTech under new national programme
People across England and Wales are set to receive faster, fairer access to innovative HealthTech under the new National HealthTech Access Programme (NHAP).
is little evidence about how this affects cost of the quality of life of patients receiving treatment. Source guidance details Comes...
range of materials and approaches are available to help dental teams advise patients on their oral health. But there is no evidence on...
There is some evidence of efficacy, but it is based on limited numbers of patients. Therefore this procedure should only be used with...
Integrated health and social care for people experiencing homelessness (NG214)
This guideline covers providing integrated health and social care services for people experiencing homelessness. It aims to improve access to and engagement with health and social care, and ensure care is coordinated across different services.
Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and management (CG84)
This guideline covers diagnosing, managing and referring infants and young children younger than 5 years who present with acute diarrhoea (lasting up to 14 days) with or without vomiting. It aims to improve the diagnosis and management of infective gastroenteritis and appropriate escalation of care.
Constipation in children and young people: diagnosis and management (CG99)
This guideline covers diagnosing and managing constipation in children and young people up to 18. It provides strategies to support the early identification and timely, effective treatment of constipation which will help improve outcomes for patients. It does not cover constipation caused by a specific condition.
is little evidence about how this affects cost of the quality of life of patients receiving treatment. Further research should be...
practice and evidence suggest that giving a combination of antibiotics to patients with moderate- to high-severity community-acquired...
poorly described in the evidence, which includes a very small number of patients. The evidence on efficacy and safety is inadequate both...
costs. Evidence suggests that doctors often fail to identify high-risk patients before surgery and do not provide perioperative...
macular degeneration (AMD) is inadequate and limited to small numbers of patients. With regard to safety, vitrectomy has well-recognised...
Attention deficit hyperactivity disorder: diagnosis and management (NG87)
This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder (ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well as the quality of care and support for people with ADHD.
This guideline covers diagnosing and managing hypertension (high blood pressure), including pre-eclampsia, during pregnancy, labour and birth. It also includes advice for women with hypertension who wish to conceive and women who have had a pregnancy complicated by hypertension. It aims to improve care during pregnancy, labour and birth for women and their babies.
certainly under-reported in the ward setting with significant implications for patients, predominantly morbidity through to mortality....