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opioids and compound analgesics) are sometimes used with disease-modifying treatments to relieve pain and stiffness when symptom control...
cost-effectiveness and enable patients to gain access to high cost drugs and treatments. What NICE does Our guidance Standards and...
NICE has developed a medtech innovation briefing (MIB) on artificial intelligence in mammography .
NICE has developed a medtech innovation briefing (MIB) on AI technologies for detecting diabetic retinopathy .
comorbidities, COVID-19 vaccination status,)• association of CAPA with COVID-19 treatments (for example, respiratory support for...
to women at high risk of developing breast cancer and considering such treatments as chemoprevention for women at moderate risk. One...
of oral health interventions to ensure equitable access to oral health treatments and services.This data is needed for evaluation...
NICE announces Professor Jonathan Benger as new Chief Executive
NICE Chairman, Sharmila Nebhrajani, today announced Professor Jonathan Benger CBE as incoming chief executive, with effect from Friday 19 December 2025 taking over from Dr Samantha Roberts.
Evidence-based recommendations on short-term circulatory support with left ventricular assist devices (LVAD) as a bridge to heart transplantation or recovery. This involves inserting a mechanical device into the chest to help the heart pump blood around the body.
View recommendations for IPG177Show all sections
Sections for IPG177
Lumbar infusion test for the investigation of normal pressure hydrocephalus (IPG263)
Evidence-based recommendations on the lumbar infusion test for the investigation of normal pressure hydrocephalus. This involves inserting a lumbar needle into the spinal sac, recording the pressure of the CSF as fluid is infused into the sac.
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Sections for IPG263
Evidence-based recommendations on percutaneous closure of patent foramen ovale for the secondary prevention of recurrent paradoxical embolism in divers. This involves passing a device through a large vessel in the groin up into the heart and closing/blocking the hole in the wall.
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Sections for IPG371
Thoracoscopic repair of congenital diaphragmatic hernia in neonates (IPG379)
Evidence-based recommendations on thoracoscopic repair of congenital diaphragmatic hernia in neonates. This involves inserting surgical instruments through small cuts in the chest, and then moving the abdominal organs out of the chest and repairing the diaphragm.
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Sections for IPG379
Evidence-based recommendations on insertion of customised exposed titanium implants, without soft tissue cover, for complex orofacial reconstruction. This involves making the titanium implants specially to fit the person using a model of their face.
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Sections for IPG457
Evidence-based recommendations on translaryngeal tracheostomy (TLT). This involves passing a tube from inside the windpipe to outside the neck to aid breathing.
However, subgroups of these people may benefit particularly from this treatment.Identifying and targeting prophylactic antibiotics for...
stratified into those with and without refractory IBS and then randomised to treatments. The primary outcome should be global...
widespread pain syndrome, which is not inflammatory. These need very different treatments, so it is important to define them accurately....
be used at an early stage as a means of preventing progression to drug treatments, which are associated with a number of undesirable...
children and young people in whom the use of appropriate non-invasive treatments did not relieve difficulties associated with spasticity...
Placement of pectus bar for pectus excavatum (also known as MIRPE or the Nuss procedure) (IPG310)
Evidence-based recommendations on placement of pectus bar for pectus excavatum (Nuss procedure). This involves placing one or two steel (pectus) bars under the breastbone with the aim of raising it and correcting the abnormal shape.
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Sections for IPG310
Endoscopic full thickness removal of non-lifting colonic polyps (IPG580)
Evidence-based recommendations on endoscopic full thickness removal of non-lifting colonic polyps. This involves using a special device to remove the polyp and seal the bowel wall closed afterwards.
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PLGF-based testing to help diagnose suspected preterm pre-eclampsia (HTG630)
Evidence-based recommendations on placental growth factor (PLGF)-based testing to help diagnose suspected preterm pre-eclampsia. The tests are: DELFIA Xpress PLGF 1-2-3, DELFIA Xpress sFlt-1/PLGF 1-2-3 ratio, Elecsys immunoassay sFlt-1/PLGF ratio, Triage PLGF Test.
recommendationsDiverticulosis is asymptomatic and there are no specific treatments for it. The committee therefore considered making a...
areavailable in oral preparations (perhaps more suitable for outpatient treatments) with establishedtreatments such as LMWH or...
non-psychotic outcomes. Why this is important:- A major problem with trials of treatments for populations of children and young people...
include details of patient selection such as body mass index and other treatments such as diet and lifestyle changes. They should also...
How we collect and use your personal information, and your rights under data protection legislation.
People living with metastatic prostate cancer in England will gain access to a new treatment combination from today (Friday, 24 October), following a recommendation by NICE.
research, the timing of selective dorsal rhizotomy in relation to other treatments such as orthopaedic surgery, and information that...
This guideline covers parenteral nutrition (intravenous feeding) for babies born preterm, up to 28 days after their due birth date and babies born at term, up to 28 days after their birth. Parenteral nutrition is often needed by preterm babies, critically ill babies, and babies who need surgery.
In development Reference number: GID-TA11546 Expected publication date: TBC
NICE has developed a medtech innovation briefing (MIB) on Airglove air warming system for venous access .
NICE has developed a medtech innovation briefing (MIB) on the S-Cath System for suprapubic catheterisations
Membership details, terms of reference, future meeting dates and past meeting minutes for our interventional procedures advisory committee.
other options for maintaining remission. Toavoid unnecessarily changing treatments for people who started taking biologics before...
What is the clinical and cost effectiveness of opioids for the management of acute sciatica?
clinical benefit. It might lead to an increased use of other recommended treatments. Full details of the evidence and the committee's...
What is the clinical and cost effectiveness of antidepressants for the management of sciatica?
clinical benefit. It might lead to an increased use of other recommended treatments. Full details of the evidence and the committee's...
In development Reference number: GID-TA11745 Expected publication date: TBC
Tralokinumab for treating moderate to severe atopic dermatitis in people aged 12 and over [ID3823]
Discontinued Reference number: GID-TA10702
Discontinued Reference number: GID-TA11339
Our centralised approach to prioritising guidance topics ensures that we produce guidance that is relevant, timely, accessible, and has demonstrable impact.
This interim process statement has been produced to guide the development of good practice guidance. It provides an overview of the key process principles and describes all stages of the development of good practice guidance
Good practice guidance – Integrated process statement (PMG12)
This process statement has been produced to explain how good practice guidance is developed. It provides an overview of the key process principles and describes all stages of the development of good practice guidance
Evidence-based recommendations on insertion of a double balloon catheter for induction of labour in pregnant women without previous caesarean section. The catheter aims to help induction by causing dilation of the cervix when the cervix is unfavourable for induction. The double balloon squeezes the cervix and stimulates local prostaglandin release, which leads to cervical ripening.
Highly specialised technologies evaluation committee members
Biographies for each member of the highly specialised technologies evaluation committee.
Biographies for all current members of the diagnostics advisory committee.
Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact M (HTG292)
Evidence-based recommendations on 3 electroencephalography (EEG)-based depth of anaesthesia monitors for assessing a patient’s response to anaesthetic drugs during surgery. The monitors are Bispectral Index (BIS), E-Entrophy and Narcotrend-Compact M.
Suture fixation of acute disruption of the distal tibiofibular syndesmosis (IPG521)
Evidence-based recommendations on suture fixation of acute disruption of the distal tibiofibular syndesmosis. This involves threading a suture through a tunnel made in the bones (tibia and fibula) and tying the ends together to fix the joint.
In development Reference number: GID-TA11251 Expected publication date: TBC
This guideline covers road-traffic-related air pollution and its links to ill health. It aims to improve air quality and so prevent a range of health conditions and deaths.