Search results

Skip to results

Area of interest

Area of interest

Type

Type

Status

Status

Last updated

Last updated

Guidance programme

Advice programme

Your search for TFRC returned no results
Showing 301 to 350 of 2490 results for term

  1. What is the clinical and cost effectiveness of treatment (antithyroid drugs or radioactive iodine) for improving long-term health outcomes for people with subclinical hyperthyroidism?

    of treatment (antithyroid drugs or radioactive iodine) for improving long-term health outcomes for people with subclinical...

    Research recommendation
    Published
    10 February 2020

  2. Managing delirium superimposed on dementia:- What are the most clinically and cost-effective non-pharmacological interventions for helping the long-term recovery of people with delirium superimposed on dementia?

    and cost-effective non-pharmacological interventions for helping the long-term recovery of people with delirium superimposed on...

    Research recommendation
    Published
    10 December 2018

  3. Long-term effect of very-low-calorie diets on people with a BMI of 40 kg/m2 or more: What are the long-term effects of using very-low-calorie diets (VLCDs) versus low-calorie diets (LCDs) on weight and quality of life in patients with a body mass index (BMI) of 40 kg/m2 or more, including the impact on weight cycling?

    Question Long-term effect of very-low-calorie diets on people with a BMI of 40 kg/m2 or more: What are the long-term...

    Research recommendation
    Published
    30 September 2022

  4. Self-management:- What is the impact of different early intervention-focused approaches to self-management on outcomes for older people with social care needs and multiple long-term conditions?

    self-management on outcomes for older people with social care needs and multiple long-term conditions? Any explanatory notes(if...

    Research recommendation
    Published
    11 December 2015

  5. Elranatamab for treating relapsed and refractory multiple myeloma after 3 or more treatments (TA1023)

    Evidence-based recommendations on elranatamab (Elrexfio) for treating relapsed and refractory multiple myeloma after 3 or more treatments in adults.

    Technology appraisal guidance
    Published
    11 December 2024
    View recommendations

    Sections for TA1023

  6. Nivolumab plus ipilimumab for untreated unresectable or metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency (TA1065)

    Evidence-based recommendations on nivolumab (Opdivo) plus ipilimumab (Yervoy) for untreated unresectable or metastatic colorectal cancer with high microsatellite instability in adults.

    Technology appraisal guidance
    Published
    28 May 2025

    Sections for TA1065

  7. Pembrolizumab with carboplatin and paclitaxel for untreated primary advanced or recurrent endometrial cancer (TA1092)

    Evidence-based recommendations on pembrolizumab (Keytruda) with carboplatin and paclitaxel for untreated primary advanced or recurrent endometrial cancer.

    Technology appraisal guidance
    Published
    27 August 2025
    View recommendations

    Sections for TA1092

  8. Ravulizumab for treating atypical haemolytic uraemic syndrome (TA710)

    Evidence-based recommendations on ravulizumab (Ultomiris) for treating atypical haemolytic uraemic syndrome in people weighing 10 kg or more.

    Technology appraisal guidance
    Published
    23 June 2021
    View recommendations

    Sections for TA710

  9. Bariatric surgery in children and young people: What are the long-term outcomes of bariatric surgery in children and young people living with obesity?

    Question Bariatric surgery in children and young people: What are the long-term outcomes of bariatric surgery in children and young...

    Research recommendation
    Published
    30 September 2022

  10. Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2 (HST12)

    Evidence-based recommendations on cerliponase alfa (Brineura) for treating neuronal ceroid lipofuscinosis type 2 in children.

    Highly specialised technologies guidance
    Published
    27 November 2019
    View recommendations

    Sections for HST12

  11. Avelumab with axitinib for untreated advanced renal cell carcinoma (TA645)

    Evidence-based recommendations on avelumab (Bavencio) with axitinib (Inlyta) for untreated advanced renal cell carcinoma in adults.

    Technology appraisal guidance
    Published
    2 September 2020
    View recommendations

    Sections for TA645

  12. Vitamin B12 deficiency in over 16s: diagnosis and management (NG239)

    This guideline covers recognising, diagnosing and managing vitamin B12 deficiency in people aged 16 and over, including deficiency caused by autoimmune gastritis. It also covers monitoring for gastric cancer in people with autoimmune gastritis.

    NICE guideline
    Published
    6 March 2024
    View recommendations

    Sections for NG239

  13. Further research into endoscopic radiofrequency therapy of the anal sphincter for faecal incontinence should clearly define the patient groups being treated. It should also report the clinical impact in terms of quality of life and long-term outcomes. NICE may review the procedure on publication of further evidence.

    being treated. It should also report the clinical impact in terms of quality of life and long-term outcomes. NICE may...

    Research recommendation
    Published
    9 June 2015

  14. Frequency of monitoring:- What is the long-term cost effectiveness, in terms of patient-relevant outcomes including bestcorrected visual acuity and quality of life, of different review frequencies/strategies for people at risk of progression to late AMD (wet active)?

    Question Frequency of monitoring:- What is the long-term cost effectiveness, in terms of patient-relevant outcomes...

    Research recommendation
    Published
    13 November 2018

  15. Epcoritamab for treating relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic treatments (TA954)

    Evidence-based recommendations on epcoritamab (Tepkinly) for treating relapsed or refractory diffuse large B-cell lymphoma in adults after 2 or more systemic treatments.

    Technology appraisal guidance
    Published
    6 March 2024
    View recommendations

    Sections for TA954

  16. Pembrolizumab plus chemotherapy with or without bevacizumab for persistent, recurrent or metastatic cervical cancer (TA939)

    Evidence-based recommendations on pembrolizumab (Keytruda) plus chemotherapy with or without bevacizumab for persistent, recurrent or metastatic cervical cancer in adults.

    Technology appraisal guidance
    Published
    13 December 2023
    View recommendations

    Sections for TA939

  17. Nintedanib for treating progressive fibrosing interstitial lung diseases (TA747)

    Evidence-based recommendations on nintedanib for treating progressive fibrosing interstitial lung diseases in adults.

    Technology appraisal guidance
    Published
    17 November 2021
    View recommendations

    Sections for TA747

  18. Fremanezumab for preventing migraine (TA764)

    Evidence-based recommendations on fremanezumab (Ajovy) for preventing migraine in adults.

    Technology appraisal guidance
    Published
    2 February 2022
    View recommendations

    Sections for TA764

  19. Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken to determine the long-term safety of tenofovir disoproxil, including the risk of clinically significant hypophosphataemia and related bone toxicity, in people with chronic hepatitis B. The cost effectiveness of routine monitoring for phosphate loss and bone disease in people with chronic hepatitis B who are receiving tenofovir disoproxil treatment needs further evaluation.

    Question Long-term safety of tenofovir disoproxil in chronic hepatitis B:- Further research should be undertaken to determine the...

    Research recommendation
    Published
    9 June 2015

  20. Infliximab for acute exacerbations of ulcerative colitis (TA163)

    Evidence-based recommendations on infliximab (Remicade) for treating acute exacerbations of severely active ulcerative colitis in adults.

    Technology appraisal guidance
    Published
    17 December 2008
    View recommendations

    Sections for TA163

  21. Diabetes in pregnancy: management from preconception to the postnatal period (NG3)

    This guideline covers managing diabetes and its complications in women who are planning pregnancy or are already pregnant. It aims to improve the diagnosis of gestational diabetes and help women with diabetes to self-manage their blood glucose levels before and during pregnancy.

    NICE guideline
    Last updated
    16 December 2020
    View recommendations

    Sections for NG3

  22. Organisational-level approaches for all organisations: What is the long-term impact and cost effectiveness of employee assistance programme provision on mental wellbeing?

    Organisational-level approaches for all organisations: What is the long-term impact and cost effectiveness of employee assistance...

    Research recommendation
    Published
    8 April 2022

  23. Evidence is adequate on the short-term safety and efficacy of personalised external aortic root support (PEARS) using mesh to prevent aortic root expansion and aortic dissection in people with Marfan syndrome. Evidence on long-term outcomes is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page. Further research should report details of patient selection, including aortic diameter, and long-term outcomes, including evidence of disease progression, such as dilation and dissection of the aortic root.

    Recommendation ID IPG724/01 Question Evidence is adequate on the short-term safety and efficacy of personalised external aortic root...

    Research recommendation
    Published
    31 May 2022

  24. Bladder management strategies:- What are the long-term risks and effects on quality of life of different bladder management strategies for lower urinary tract dysfunction in people with neurological disease?

    CG148/4 Question Bladder management strategies:- What are the long-term risks and effects on quality of life of different bladder...

    Research recommendation
    Published
    9 June 2015

  25. Rheumatoid arthritis in over 16s (QS33)

    This quality standard covers assessing, diagnosing and managing rheumatoid arthritis in over 16s. It describes high-quality care in priority areas for improvement.

    Quality standard
    Last updated
    9 January 2020
    View quality statements

    Sections for QS33

  26. What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary incontinence and pelvic organ prolapse in women?

    Recommendation ID NG123/5 Question What are the long-term risks of mesh surgery compared with non-mesh surgery for stress urinary...

    Research recommendation
    Published
    21 June 2019

  27. Imlifidase for desensitisation treatment before kidney transplant in people with chronic kidney disease (TA809)

    Evidence-based recommendations on imlifidase (Idefirix) for desensitisation treatment before kidney transplant in people with chronic kidney disease.

    Technology appraisal guidance
    Published
    20 July 2022
    View recommendations

    Sections for TA809

  28. Ponesimod for treating relapsing–remitting multiple sclerosis (TA767)

    Evidence-based recommendations on ponesimod (Ponvory) for treating relapsing–remitting multiple sclerosis in adults.

    Technology appraisal guidance
    Published
    2 February 2022
    View recommendations

    Sections for TA767

  29. Entecavir for the treatment of chronic hepatitis B (TA153)

    Evidence-based recommendations on entecavir for treating chronic hepatitis B in adults.

    Technology appraisal guidance
    Published
    27 August 2008
    View recommendations

    Sections for TA153

  30. Tocilizumab for the treatment of rheumatoid arthritis (TA247)

    Evidence-based recommendations on tocilizumab (RoActemra) for treating rheumatoid arthritis in adults.

    Technology appraisal guidance
    Published
    22 February 2012
    View recommendations

    Sections for TA247

  31. Evidence on the safety of endoluminal gastroplication for gastro-oesophageal reflux disease is adequate. However, evidence on its efficacy is inadequate in quality, particularly in terms of patient selection and long-term outcomes. Therefore, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    its efficacy is inadequate in quality, particularly in terms of patient selection and long-term outcomes. Therefore, this...

    Research recommendation
    Published
    27 April 2023

  32. Tuberculosis (QS141)

    This quality standard covers preventing, identifying and managing latent and active tuberculosis (TB) in children, young people and adults. It describes high-quality care in priority areas for improvement. It does not cover areas of national policy, such as the UK Bacillus Calmette-Guérin (BCG) immunisation programme.

    Quality standard
    Published
    10 January 2017
    View quality statements

    Sections for QS141

  33. Urinary incontinence in neurological disease: assessment and management (CG148)

    This guideline covers assessing and managing urinary incontinence in children, young people and adults with neurological disease. It aims to improve care by recommending specific treatments based on what symptoms and neurological conditions people have.

    Clinical guideline
    Last updated
    2 October 2023
    View recommendations

    Sections for CG148

  34. Idebenone for treating visual impairment in Leber's hereditary optic neuropathy in people 12 years and over (TA1093)

    Evidence-based recommendations on idebenone (Raxone) for treating visual impairment in Leber’s hereditary optic neuropathy in people 12 years and over.

    Technology appraisal guidance
    Published
    28 August 2025

    Sections for TA1093

  35. Approaches for micro, small and medium-sized enterprises: What is the long-term effectiveness of universal individual-level interventions in different kinds of SMEs?

    Approaches for micro, small and medium-sized enterprises: What is the long-term effectiveness of universal individual-level...

    Research recommendation
    Published
    8 April 2022

  36. Evidence on the efficacy of focal resurfacing implants to treat articular cartilage damage in the knee is limited in quality and quantity. Short-term evidence shows no major safety concerns, but long-term evidence on safety is limited in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    knee is limited in quality and quantity. Short-term evidence shows no major safety concerns, but long-term evidence on...

    Research recommendation
    Published
    7 September 2022

  37. Spesolimab for treating generalised pustular psoriasis flares (TA1070)

    Evidence-based recommendations on spesolimab (Spevigo) for treating generalised pustular psoriasis flares in adults.

    Technology appraisal guidance
    Published
    18 June 2025
    View recommendations

    Sections for TA1070

  38. Attention deficit hyperactivity disorder: diagnosis and management (NG87)

    This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder (ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well as the quality of care and support for people with ADHD.

    NICE guideline
    Last updated
    13 September 2019
    View recommendations

    Sections for NG87

  39. Are there effective long-term pharmacological interventions to prevent the onset of type 2 diabetes that can be recommended postnatally for women who have been diagnosed with gestational diabetes?

    Recommendation ID NG3/5 Question Are there effective long-term pharmacological interventions to prevent the onset of type 2 diabetes that

    Research recommendation
    Published
    9 June 2015

  40. Fetal monitoring in labour (NG229)

    This guideline covers methods for monitoring the wellbeing of the baby during labour. It includes risk assessment to determine the appropriate level of fetal monitoring, using clinical assessment in addition to fetal monitoring, and interpreting and acting on monitoring findings.

    NICE guideline
    Last updated
    12 November 2025
    View recommendations

    Sections for NG229

  41. Acute respiratory infection in over 16s: initial assessment and management including virtual wards (hospital at home) (QS210)

    This quality standard covers the initial assessment and management of suspected acute respiratory infection in over 16s, including acute respiratory infection virtual wards.

    Quality standard
    Published
    31 October 2023
    View quality statements

    Sections for QS210

  42. Which interventions are effective and cost effective in supporting people working in organisations where employees are not centrally located to return to work after long-term sickness absence in the UK?

    organisations where employees are not centrally located to return to work after long-term sickness absence in the UK? Any explanatory...

    Research recommendation
    Published
    10 February 2020

  43. What is the natural history of people with a Likert score on MRI of less than 3 without biopsy at long-term follow‑up?

    of people with a Likert score on MRI of less than 3 without biopsy at long-term follow‑up? Any explanatory notes(if applicable) Why the...

    Research recommendation
    Published
    25 October 2019

  44. Gastroparesis in adults: oral erythromycin (ESUOM13)

    Summary of the evidence on oral erythromycin for gastroparesis (delayed stomach emptying) in adults to inform local NHS planning and decision-making

    Evidence summary
    Published
    18 June 2013

  45. Infliximab and adalimumab for the treatment of Crohn's disease (TA187)

    Evidence-based recommendations on infliximab (Remicade) and adalimumab (Humira) for treating severe active Crohn's disease in adults.

    Technology appraisal guidance
    Published
    19 May 2010
    View recommendations

    Sections for TA187

  46. Promoting health and preventing premature mortality in black, Asian and other minority ethnic groups (QS167)

    This quality standard covers promoting health and preventing premature mortality among black, Asian and other minority ethnic groups. It is relevant to all age groups and all settings.

    Quality standard
    Published
    11 May 2018
    View quality statements

    Sections for QS167

  47. Nivolumab for previously treated unresectable advanced or recurrent oesophageal cancer (TA707)

    Evidence-based recommendations on Nivolumab (Opdivo) for previously treated unresectable advanced, recurrent or metastatic oesophageal squamous cell carcinoma in adults.

    Technology appraisal guidance
    Published
    15 June 2021
    View recommendations

    Sections for TA707

  48. Setmelanotide for treating obesity caused by LEPR or POMC deficiency (HST21)

    Evidence-based recommendations on setmelanotide (Imcivree) for treating obesity caused by LEPR or POMC deficiency in people 6 years and over.

    Highly specialised technologies guidance
    Published
    6 July 2022
    View recommendations

    Sections for HST21

  49. Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolism (TA287)

    Evidence-based recommendations on rivaroxaban (Xarelto) for treating pulmonary embolism and for preventing a further deep vein thrombosis or pulmonary embolism in adults.

    Technology appraisal guidance
    Published
    26 June 2013
    View recommendations

    Sections for TA287

  50. NICE encourages further research into radiofrequency ablation of the soft palate for snoring. This could take the form of data collection, with the specific aim of documenting long-term outcomes and the need for further treatment.

    take the form of data collection, with the specific aim of documenting long-term outcomes and the need for further treatment. Any...

    Research recommendation
    Published
    9 June 2015