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Guidance programme

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Showing 3451 to 3500 of 3761 results for treatment

  1. Ivosidenib for treating relapsed or refractory IDH1-positive acute myeloid leukaemia [ID1548]

    Discontinued Reference number: GID-TA10416

  2. Datopotamab deruxtecan for treating advanced non-small-cell lung cancer after platinum-based chemotherapy [ID6241]

    In development Reference number: GID-TA11277 Expected publication date: TBC

  3. The social care guidance manual (PMG10)

    This manual explains how NICE develops and updates social care guidance. It provides advice on the technical aspects of guidance development and the methods used

  4. Transperineal biopsy for diagnosing prostate cancer (HTG680)

    Evidence-based recommendations on transperineal biopsy for diagnosing prostate cancer.

  5. Atezolizumab in combination with platinum-based chemotherapy for untreated locally advanced or metastatic urothelial cancer [ID1206]

    Discontinued Reference number: GID-TA10202

  6. YOURmeds for medication support in long-term conditions (MIB289)

    NICE has developed a medtech innovation briefing (MIB) on YOURmeds for medication support in long-term conditions .

  7. E-cigarette flavours: Do the flavours used in nicotine-containing e‑cigarettes have an impact on their effectiveness as an aid to stopping smoking, and are there any adverse effects associated with them?

    committee's discussion are in evidence review K: cessation and harm-reduction treatments. Source guidance details Comes from guidance...

  8. Use of e-cigarettes (amount and frequency): Does the effectiveness of nicotine-containing e‑cigarettes as an aid to stopping smoking vary according to the amount of nicotine they contain or the frequency of use?

    committee's discussion are in evidence review K: cessation and harm-reduction treatments. Source guidance details Comes from guidance...

  9. Active surveillance compared with surgery: For people with stage 1 differentiated thyroid cancer, what is the clinical and cost effectiveness of active surveillance compared with surgery?

    evidence and the committee's discussion are in evidence review H: initial treatments for differentiated thyroid cancer. Source guidance...

  10. What is the clinical and cost effectiveness of auto- and fixed-level continuous positive airway pressure (CPAP) for managing moderate and severe OSAHS?

    committee made the recommendation for research, see the rationale section on treatments for moderate and severe OSAHS . Full details of...

  11. Mandibular advancement splints for severe OSAHS: What is the clinical and cost effectiveness of mandibular advancement splints for managing severe OSAHS?

    committee made the recommendation for research, see the rationale section on treatments for moderate and severe OSAHS. Full details of...

  12. i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department (MIB38)

    NICE has developed a medtech innovation briefing (MIB) on i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department

  13. Use of hearing aids and incidence of dementia:- In adults with hearing loss, does the use of hearing aids reduce the incidence of dementia?

    people with dementia, their families and the NHS, and there is no effective treatment to prevent its progression.Hearing loss is...

  14. E-cigarettes for harm reduction: Are nicotine-containing e‑cigarettes effective and safe for harm reduction when used alongside tobacco products to cut down on smoking (dual-use approach)?

    committee's discussion are in evidence review K: cessation and harm-reduction treatments. Source guidance details Comes from guidance...

  15. Auto- versus fixed-level CPAP for OSAHS: What is the clinical and cost effectiveness of auto- and fixed-level continuous positive airway pressure (CPAP) for managing mild obstructive sleep apnoea/hypopnoea syndrome (OSAHS)?

    committee made the recommendation for research, see the rationale section on treatments for mild OSAHS . Full details of the evidence...

  16. Stop-smoking interventions for under-served groups: How can effective and cost-effective interventions to support people to stop smoking be modified to improve engagement with and accessibility for under-served groups? How acceptable are these interventions to these groups?

    committee's discussion are in evidence review K: cessation and harm-reduction treatments. Source guidance details Comes from guidance...

  17. Health effects of e-cigarettes: What are the short- and long-term health effects of e-cigarette use? Are there any specific health effects relating to use in pregnancy, or use by children and young people?

    discussion are in: - evidence review K: cessation and harm-reduction treatments - evidence review M: long-term health effects of...

  18. Behaviour change: individual approaches (PH49)

    This guideline covers changing health-damaging behaviours among people aged 16 and over using interventions such as goals and planning, feedback and monitoring, and social support. It aims to help tackle a range of behaviours including alcohol misuse, poor eating patterns, lack of physical activity, unsafe sexual behaviour and smoking.

  19. Analgesics:- What is the clinical and cost effectiveness of analgesic drugs other than non-steroidal antiinflammatory drugs (NSAIDs) in adults with rheumatoid arthritis (RA) whose pain or stiffness control is not adequate?

    opioids and compound analgesics) are sometimes used with disease-modifying treatments to relieve pain and stiffness when symptom control...

  20. What risk factors in people who are critically ill and have, or have had, COVID-19 as part of their acute illness are associated with developing COVID-19-associated pulmonary aspergillosis (CAPA)?

    comorbidities, COVID-19 vaccination status,)• association of CAPA with COVID-19 treatments (for example, respiratory support for...

  21. Past research and projects

    NICE's past research and projects

  22. The OSCAR 3 ultrasonic arthroplasty revision instrument for removing bone cement during prosthetic joint revision (MIB13)

    NICE has developed a Medtech Innovation Briefing (MIB) on the OSCAR 3 ultrasonic arthroplasty revision instrument for removing bone cement during prosthetic

  23. Effectiveness and costs of oral health interventions for care home residents:- How effective and cost effective are oral health interventions in care homes including suitableperson-centred outcome measures?

    of oral health interventions to ensure equitable access to oral health treatments and services.This data is needed for evaluation...

  24. Prophylactic antibiotics for preventing exacerbations:- Which subgroups of people with stable COPD who are at high risk of exacerbations are most likely to benefit from prophylactic antibiotics?

    However, subgroups of these people may benefit particularly from this treatment.Identifying and targeting prophylactic antibiotics for...

  25. Relaxation and biofeedback:- What is the effect of relaxation and biofeedback therapies on [Irritable bowel syndrome] (IBS) symptoms and patient-related outcomes?

    stratified into those with and without refractory IBS and then randomised to treatments. The primary outcome should be global...

  26. Ultrasound in monitoring:- What is the clinical and cost effectiveness of using ultrasound to monitor disease in adults with RA when clinical examination is inconclusive or inconsistent with other signs of disease activity?

    widespread pain syndrome, which is not inflammatory. These need very different treatments, so it is important to define them accurately....

  27. Is chamomile/ginkgo biloba more effective than placebo in increasing response and remission rates and decreasing anxiety ratings for people with generalised anxiety disorder (GAD)?

    be used at an early stage as a means of preventing progression to drug treatments, which are associated with a number of undesirable...

  28. Intrathecal baclofen:- What is the clinical and cost effectiveness of continuous pump-administered intrathecal baclofen compared with usual care in children and young people who are at Gross Motor Function Classification System (GMFCS) level IV or V?

    children and young people in whom the use of appropriate non-invasive treatments did not relieve difficulties associated with spasticity...

  29. The hTEE system for transoesophageal echocardiographic monitoring of haemodynamic instability (MIB7)

    NICE has developed a Medtech Innovation Briefing (MIB) on the hTEE system for transoesophageal echocardiographic monitoring of haemodynamic instability

  30. What is the most clinically and cost-effective conservative management for preventing diverticular disease in people with diverticulosis?

    recommendationsDiverticulosis is asymptomatic and there are no specific treatments for it. The committee therefore considered making a...

  31. Direct oral anticoagulants for people with lower limb immobilisation:- What is the clinical and cost effectiveness of direct oral anticoagulants for preventing VTE in people with lower limb immobilisation?

    areavailable in oral preparations (perhaps more suitable for outpatient treatments) with establishedtreatments such as LMWH or...

  32. Insertion of a double balloon catheter for induction of labour in pregnant women without previous caesarean section (HTG380)

    Evidence-based recommendations on insertion of a double balloon catheter for induction of labour in pregnant women without previous caesarean section. The catheter aims to help induction by causing dilation of the cervix when the cervix is unfavourable for induction. The double balloon squeezes the cervix and stimulates local prostaglandin release, which leads to cervical ripening.

  33. Charging procedure

    Charging procedure for NICE technology appraisal and highly specialised technologies evaluations

  34. Indoor air quality at home (NG149)

    This guideline covers indoor air quality in residential buildings. It aims to raise awareness of the importance of good air quality in people's homes and how to achieve this.

  35. Mental wellbeing at work (NG212)

    This guideline covers how to create the right conditions for mental wellbeing at work. It aims to promote a supportive and inclusive work environment, including training and support for managers and helping people who have or are at risk of poor mental health.

  36. Robot-assisted surgery for orthopaedic procedures: early value assessment (HTG743)

    Early value assessment (EVA) guidance on robot-assisted surgery for orthopaedic procedures.

  37. Artificial intelligence in mammography (MIB242)

    NICE has developed a medtech innovation briefing (MIB) on artificial intelligence in mammography .

  38. AI technologies for detecting diabetic retinopathy (MIB265)

    NICE has developed a medtech innovation briefing (MIB) on AI technologies for detecting diabetic retinopathy .

  39. NICE announces Professor Jonathan Benger as new Chief Executive

    NICE Chairman, Sharmila Nebhrajani, today announced Professor Jonathan Benger CBE as incoming chief executive, with effect from Friday 19 December 2025 taking over from Dr Samantha Roberts.

  40. Trastuzumab deruxtecan for treating HER2-positive unresectable or metastatic breast cancer after 1 or more anti-HER2 treatments [ID6309]

    In development Reference number: GID-TA11546 Expected publication date: TBC

  41. Selective dorsal rhizotomy:- Does selective dorsal rhizotomy followed by intensive rehabilitation performed between the ages of 3 and 9 years in children who are at Gross Motor Function Classification System (GMFCS) level II or III result in good community mobility as a young adult?

    research, the timing of selective dorsal rhizotomy in relation to other treatments such as orthopaedic surgery, and information that...

  42. Suture fixation of acute disruption of the distal tibiofibular syndesmosis (HTG374)

    Evidence-based recommendations on suture fixation of acute disruption of the distal tibiofibular syndesmosis. This involves threading a suture through a tunnel made in the bones (tibia and fibula) and tying the ends together to fix the joint.

  43. PLGF-based testing to help diagnose suspected preterm pre-eclampsia (HTG630)

    Evidence-based recommendations on placental growth factor (PLGF)-based testing to help diagnose suspected preterm pre-eclampsia. The tests are: DELFIA Xpress PLGF 1-2-3, DELFIA Xpress sFlt-1/PLGF 1-2-3 ratio, Elecsys immunoassay sFlt-1/PLGF ratio, Triage PLGF Test.

  44. Airglove air warming system for venous access (MIB151)

    NICE has developed a medtech innovation briefing (MIB) on Airglove air warming system for venous access .

  45. What are the benefits, risk and cost effectiveness of enteral nutrition in maintaining remission in the post-surgical period of Crohn's disease?

    other options for maintaining remission. Toavoid unnecessarily changing treatments for people who started taking biologics before...

  46. Axatilimab for treating active chronic graft-versus-host disease after 2 or more systemic treatments in people 2 years and over [ID6570]

    In development Reference number: GID-TA11745 Expected publication date: TBC

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