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Showing 1276 to 1290 of 2208 results for guidelines

  1. HTG EdgeSeq ALKPlus Assay EU for ALK status testing in non-small-cell lung cancer (MIB128)

    NICE has developed a medtech innovation briefing (MIB) on HTG EdgeSeq ALKPlus Assay EU for ALK status testing in non-small-cell lung cancer .

    Medtech innovation briefing
    Published
    7 November 2017

  2. Clean air zones:- How do different elements of a clean air zone interact to improve air quality and what is the overall effect on people's health?

    notes(if applicable) Why this is important:- At publication of this guideline, clean air zones were being introduced. These zones are...

    Research recommendation
    Published
    12 October 2018

  3. Effective prevention of child abuse and neglect in the UK:- What interventions are effective and cost effective in the UK to prevent abuse and neglect of children and young people in families at risk of, or showing early signs of, abuse and neglect?

    applicable) Why this is important:- The evidence reviewed for this guideline on the effectiveness of interventions to prevent abuse and...

    Research recommendation
    Published
    18 October 2018

  4. What is the improvement in the cost-effectiveness metrics for statin therapy in reducing CVD that can be obtained when using a complete individual patient-based outcomes meta-analysis data set compared with using published outcomes data?

    Any explanatory notes(if applicable) Why this is important: This guideline development process uses published summary data from trials...

    Research recommendation
    Published
    9 June 2015

  5. Orthostatic hypotension treatment:- For people with Parkinson's disease, what is the most effective pharmacological treatment for orthostatic hypotension?Particular interventions and comparisons of interest are:- midodrine compared with fludrocortisone (primary comparison)- pyridostigmine- ephedrine - pseudoephedrine.

    Any explanatory notes(if applicable) Why this is important:- The guideline committee felt that orthostatic hypotension was an important...

    Research recommendation
    Published
    15 October 2018

  6. Mid-life interventions:- In the UK, which mid-life groups are currently at most risk of losing their independence or experiencing poor mental wellbeing in later life? And which interventions are most effective and cost effective in preparing these people for later life?

    help commissioners and providers to evaluate their services, and inform guideline updates. Source guidance details Comes from guidance

    Research recommendation
    Published
    25 January 2016

  7. What risk factors in people who are critically ill and have, or have had, COVID-19 as part of their acute illness are associated with developing COVID-19-associated pulmonary aspergillosis (CAPA)?

    Source guidance details Comes from guidance COVID-19 rapid guideline: managing COVID-19 Number NG191 Date issued March

    Research recommendation
    Published
    17 December 2021

  8. What is the effectiveness and safety of extended pharmacological venous thromboembolism (VTE) prophylaxis for people who have been discharged after treatment for COVID-19?

    Source guidance details Comes from guidance COVID-19 rapid guideline: managing COVID-19 Number NG191 Date issued March

    Research recommendation
    Published
    10 August 2021

  9. Expectant management before IVF:- What is the optimum period of expectant management for women of different age groups before invasive treatment such as IVF is considered?

    with advancing age because of a woman's decreasing ovarian reserve. The guideline currently recommends a shorter period of expectant...

    Research recommendation
    Published
    9 June 2015

  10. Apart from culture, what other diagnostic tests or combinations of tests are effective inestablishing an accurate diagnosis of active respiratory TB in children and young people withsuspected active TB?

    Any explanatory notes(if applicable) Why this is important The guideline committee noted the lack of evidence on the diagnosis of active...

    Research recommendation
    Published
    8 November 2019

  11. Effectiveness of web-based parenting programmes:- Are web-based parenting programmes effective and cost effective for improving parenting and preventing recurrence of child abuse and neglect in families where child abuse or neglect has occurred?

    families where child abuse or neglect has occurred. Our review for this guideline identified 1 small-scale US study of a web-based...

    Research recommendation
    Published
    18 October 2018

  12. Newly diagnosed seizures (focal and generalised) – monotherapy: How do the newer AEDs compare in efficacy to the standard AEDs in the treatment of newly diagnosed epilepsy? Focal seizures: carbamazepine, eslicarbazepine acetate, lacosamide, lamotrigine, levetiracetam, pregabalin  and zonisamide. Generalised seizures: lamotrigine, levetiracetam, sodium valproate and zonisamide.

    focal and generalised seizures since publication of the original NICE guideline on epilepsy in 2004 have not been evaluated as...

    Research recommendation
    Published
    13 August 2021

  13. What is the effectiveness and safety of neutralising monoclonal antibodies against different SARS-CoV-2 variants?

    Source guidance details Comes from guidance COVID-19 rapid guideline: managing COVID-19 Number NG191 Date issued March

    Research recommendation
    Published
    9 March 2022

  14. Adding a newer anti-anginal drug to a calcium channel blocker:- What is the clinical and cost effectiveness of adding a newer anti-anginal drug (nicorandil, ivabradine or ranolazine) to a calcium channel blocker for treating stable angina?

    clinical practice and inform future updates of key recommendations in this guideline. Source guidance details Comes from guidance Stable...

    Research recommendation
    Published
    9 June 2015

  15. Carrier probability calculation models:- Further research is recommended into developing and validating models for calculating carrier probability, which incorporate additional data, such as the molecular pathology of tumours and the prevalence of mutations in different ethnic groups. [new 2013]

    Any explanatory notes(if applicable) Why this is important:- This guideline recommends offering genetic testing to people with a 10%...

    Research recommendation
    Published
    9 June 2015