Find out more about the members of TAC C by reading their biographies.

Professor Stephen G O'Brien BSc (Hons) PhD MBChB FRCP MRCPath


Professor of haematology at Newcastle University and honorary consultant haematologist at Newcastle Hospitals NHS Foundation Trust

More about Stephen

Stephen is an academic clinician with an interest in leukaemia research. Following graduation and general medicine experience in Manchester he trained in haematology, completing a PhD in the molecular biology of leukaemia, at the Hammersmith Hospital in London.

He treated the first UK patients to receive imatinib and continues to be closely involved with ongoing trials of tyrosine kinase inhibitors in chronic myeloid leukaemia. As well as looking after NHS patients with haematological malignancies, Professor O’Brien is the chief investigator for the National Cancer Research Network’s SPIRIT trials in CML, involving over 1,000 patients in 150 UK hospitals and is a member of the NCRN Haem Onc Clinical Studies Group.

Richard Nicholas

Vice chair

Iftab Akram

Specialist optometrist and lead optometrist for Mid Yorkshire NHS Trust

More about Iftab

Iftab is a specialist optometrist and currently the lead optometrist for Mid Yorkshire NHS Trust. His experience in Ophthalmology includes the specialties: macula, medical retina and glaucoma. He is also the optometry clinical lead for a primary care network in Chesterfield. He continues to work on an ad-hoc basis in community optometry practice and has recently commenced work with the NHS England Special School Eye Care service.

He has previously held a clinical supervisor role with the University of Bradford supporting the Optometry programme. He has also worked for the national diabetic eye screening programme.

He has completed a number of College of Optometrist’s approved higher qualifications and aiming to complete his MSc soon.

Dr Alex Cale

Mike Chambers

Director, MC Healthcare Evaluation

More about Mike

With degrees in mathematical philosophy (University of Cambridge), demography (LSE) and health economics (University of York), Mike Chambers is currently founder and director of MC Healthcare Evaluation. From 2006 to 2015 he worked for GlaxoSmithKline as director of health economics and latterly as head of reimbursement and value demonstration.

Previously he worked in the UK NHS (district information officer), at London Hospital Medical College (lecturer in department of epidemiology and medical statistics), MEDTAP International (contract research in economic evaluation) and as head of health economics at Amersham Health/GE Healthcare.

His main research interests have been in the development and application of principles of evidence-based medicine and in the methods and processes of health technology assessment, in particular the use of economic modelling and real world evidence to inform decision-making.

Dr Prithwiraj Das

Senior health economist, Boehringer Ingelheim Ltd

More about Prithwiraj

Prithwiraj is a medical doctor (MBBS, Gold Medallist) with a programming background. He has a Masters degree in International Health Policy from the London School Economics (LSE).

Across 15+ years of experience spanning clinical, academic, medical devices, consulting, and pharmaceuticals, his aim has consistently been to solve complex problems in getting patients access to health technologies.

Prithwiraj currently manages a team of health economists and works as the market access lead for speciality medicines at Boehringer Ingelheim Ltd, in the UK and Ireland, covering multiple therapy areas (oncology, inflammation, thrombolysis).

Chamkhor Dhillon

Registered pharmacist

More about Chamkhor

Chamkhor is a registered Pharmacist and a Senior Project Manager at the North East London Cancer Alliance, primarily supporting the early diagnosis programme.

He began his pharmacy training in community before moving to Nottingham as a clinical pharmacist based in the surgical division. He continues to practice in community pharmacy and is a member of the Royal Pharmaceutical Society. Chamkhor completed the Policy and Strategy Graduate Management Scheme and undertook various roles across NHS England & Improvement, secondary care and health consultancy. He also completed a secondment at the Department of Health and Social Care, where he supported the national team in assessing risks and providing solutions to medicine supply issues and shortages during Covid-19.

Chamkhor obtained a Master of Pharmacy (MPharm) degree from Aston University, where he completed an evaluation on the use of psychotropic medication in people with intellectual disabilities. He also has a postgraduate diploma in Health Policy from Imperial Collage London, and a postgraduate certificate in Healthcare leadership from University of Birmingham.

David Foreman


More about David

David is a consultant child and adolescent psychiatrist who has combined a clinical and academic career. Current interests include the impact of information within a public policy and public mental health framework. This includes their use within policy instruments and developing scalable approaches to psychopathology. These have derived from a long-standing interest in perinatal mental health and infant psychiatry, as well as measurement and detection of common psychiatric disorders especially ADHD. He also has a long-standing interest in biomedical ethics.

He is now demitting from the committees of the Perinatal and Child and Adolescent Faculties of the Royal College of Psychiatrists after 6 years. His roles there included data, early years and liaison between the two committees. He continues his academic connection to IoPPN, King's College. He has retired from full-time NHS work, but continues to see patients in private practice.

Rob Forsyth

Senior lecturer at Newcastle University and honorary consultant in paediatric neurology for Newcastle Hospitals NHS Foundation Trust

More about Rob

After qualifying from Cambridge and Oxford, Rob trained in Nottingham and Newcastle with subspecialty training in Vancouver. His research interests centre on translational research in paediatric acquired brain injury and rehabilitation and epilepsy.

Rob is an active acute paediatric neurologist. His clinical responsibilities include co-ordination of the inpatient acquired brain injury service. He was UK national training advisor in paediatric neurology 2003-9. He is editor of the Oxford Specialist Handbook in Paediatric Neurology (third edition 2017). He was on the editorial boards of Developmental Medicine and Child Neurology 2005-11 and European Journal of Paediatric Neurology 2013 to present. He is currently secretary of the European Paediatric Neurology Society.

Dr Pedro Saramago Goncalves

Senior health economist at the Centre for Health Economics, University of York

More about Pedro

Pedro is Senior health economist at the Centre for Health Economics, University of York. He has a first degree in Applied Mathematics and a postgraduation in Biostatistics from the University of Lisbon. Also, Pedro holds a MSc and a PhD in Health Economics, both from the University of York.

Pedro has over 15 years of experience in health technology assessment, health economics and health services research. He has an extensive research portfolio, including both applied and methodological research, with expertise in statistical analysis of primary data, evidence synthesis, Bayesian methods, decision modelling, survival analysis and value of information analyses.

Dr Natalie Hallas

Senior health economics and commissioning manager, Medtronic UK and Ireland

More about Natalie

Natalie is a senior health economics and commissioning manager with over 10 years' experience in the medical device industry. Natalie completed her PhD in cardiovascular physiology at Brunel University alongside providing exercise physiology support to athletes, before joining Medtronic in 2006 as a clinical research specialist. In this role she managed multi-centre clinical trials in various geographies including Australia and New Zealand.

Natalie holds a Postgraduate Diploma in Health Economics from the University of York, which she is now applying to her current role in relation to a range of medical technologies.

Mr John Hampson

Public health specialist, Cheshire West and Chester Council and lead for medicines management for the Cheshire and Merseyside Public Health Collaborative (Champs)

More about John

John has worked as a public health specialist since 2004 in Primary Care Trusts (PCTs) and subsequently in a local authority. He is currently a consultant in public health working for the individual funding request and clinical policy development teams of the Chester-based NHS clinical support unit. He initially trained as a pharmacist and has over 20 years’ experience working in various hospitals in a variety of roles including formulary work, clinical pharmacy, education and in academia.

The main focus of his public health role is evidence-based practice and involves critical appraisal of the literature for policy and strategy development at county and regional levels. During his time with the local authority, he provided medicines management advice to the public health departments in the local authorities of Cheshire and Merseyside.

Research interests have included antimicrobial therapy, diabetes and pharmacoepidemiology.

Dr Nigel Langford

Consultant acute physician and clinical pharmacologist

More about Nigel

Nigel Langford is a consultant acute physician and clinical pharmacologist at Leicester Royal Infirmary, graduating from the Leicester Medical School in 1995. Prior to qualifying he had also worked as a pharmacist and retains membership of the Royal Pharmaceutical Society. He was awarded an MD in clinical pharmacology in 2005 from the University of Birmingham.

He has a long-standing interest in medical education, medical error and adverse drug reactions. He was a member of the NICE guideline development group for two guidelines looking at the prevention, identification and management of venous thromboembolic diseases. He is an honorary senior lecturer to the Leicester Medical School. In addition to his specialist work he remains active in acute and general medicine.

Professor Andrea Manca

Professor of health economics, University of York

More about Andrea

Andrea is Professor of Health Economics in the Centre for Health Economics at the University of York. His research focuses on developing methodological solutions to address the issues faced by researchers and decision makers when analysing and interpreting health economics and outcomes research data. This involves using statistical and decision modelling techniques for the analysis of cost effectiveness data, including quantitative evidence synthesis and health econometrics methods.

He has more than 20 years' experience in his field. He has evaluated a wide range of health technologies (therapeutic medical devices, drugs, diagnostics and non pharmaceutical interventions) in several clinical areas including oncology, cardiology and respiratory diseases, diabetes, chronic pain, surgical interventions, obstetrics and gynaecology.

Andrea received the 2008 ISPOR Award for Excellence in Methodology in Pharmacoeconomics and Health Outcomes Research for his contributions to the literature on the analysis of multinational individual patient level cost effectiveness data where the objective is to inform reimbursement decisions in different jurisdictions. He currently leads a research programme on the economics of stratified, precision and personalised medicine.

Iain McGowan

Lecturer in education (mental health), Queens University, Belfast

More about Iain

Iain qualified as a mental health nurse in 1998 and has worked in nurse education since 2001. He is a former board member of the Northern Ireland Practice and Education Council for Nursing and Midwifery.

His research interests include health economics, post-traumatic stress disorder and heroin use. He is currently a member of the editorial board of the International Journal of Psychiatry and Mental Health, and former editor in chief of the editorial board of the International Journal of Clinical Psychiatry.

Iain was awarded a post-graduated diploma in Applied Health Economics from the University of Wales in 2018. From September 2019 he's studying for his PhD in Health Economics and Policy at the University of Lancaster.

Kirandip Moyo

Pharmacy advisor, Specialised Commissioning, NHS England

More about Kirandip

Kirandip graduated in 2011 from the University of Kent with a Masters degree in pharmacy. Since graduation she has worked as a pharmacist in a wide range of clinical roles, within a variety of London teaching hospitals and community pharmacies. During this time she also obtained a Clinical Diploma in pharmacy practice from University College London.

Her most recent roles have centered on commissioning of medications and ensuring that appropriate local clinical guidelines are in place for medications being used across the healthcare systems.

Currently Kirandip is a pharmacy advisor for NHS England in Specialised Commissioning for the London Region. She is interested in health economics and is passionate about ensuring patients have access to appropriate evidence-based treatments, and that such treatments are being used safely and effectively.

Dr Mudasar Mushtaq

General practitioner

More about Mudasar

Mudasar graduated with honours in medicine and surgery (MBChB) from the University of Liverpool. He went on to train as a general practitioner in the North West. Currently he works in Greater Manchester providing primary care in a variety of settings.

Mudasar is also working in the clinical trials team at The Christie Hospital in Medical Oncology, with the latest technologies in clinical trials in patients with head and neck cancer.

Mudasar is passionate about delivering gold standard healthcare and has a strong interest in evidence-based medicine and health economics. He is currently undertaking a master’s in health economics, policy and management at the London School of Economics.

Ugochi Nwulu

Applied health researcher

About Ugochi

Ugochi is an applied health researcher with experience of evaluating health services and interventions in a number of healthcare settings, but mainly secondary care. Her areas of interest are in patient safety, quality improvement and variations in healthcare. She is currently completing a PhD at Hull York Medical School, which is part of an evaluation of an integrated care clinic providing proactive anticipatory care for patients with moderate to severe frailty.

Ugochi uses her experiences as a gynaecology patient to advocate for women in similar positions. She has been a lay member on a NICE guideline update committee (NG88, 2018) and a specialist lay member of a quality standards advisory committee for the same guideline. She is currently a member of the Royal College of Obstetricians and Gynaecologists (RCOG) Women’s Network and scientific advisory committees, as well as a lay examiner for the RCOG part 3 membership exams.

Stella O'Brien

Professor Subhash Pokhrel

Professor of health economics and head of the Clinical Sciences Department, Brunel University

More about Subhash

Subhash is a professor of health economics and head of the Clinical Sciences Department at Brunel University London. He also leads the Health Economics Research Group (HERG) at Brunel. His main work is around evidence synthesis in healthcare and evaluation of cost-effectiveness of (public) health interventions. He has previously contributed to NICE guidelines development as a member of an external assessment centre. He is the lead author of the recent book, 'ROI in Public Health Policy: Supporting Decision Making' (Palgrave Macmillan).

Professor Andrew Renehan

Professor of cancer studies and surgery, University of Manchester and honorary consultant in colorectal and peritoneal surgery, Christie NHS Foundation Trust

More about Andrew

Andrew holds honorary degrees in dentistry from Trinity College, Dublin and medicine from University of Manchester. He did his PhD in cancer sciences at the Paterson Cancer Research Institute, Manchester. His main clinical and research field is specialist colorectal surgery, especially cancers of the anus, rectum, and peritoneum.

He is currently chair of the European Association of the Study of Diabetes Cancer Study Group and previous member of the International Agency for Research in Cancer Weight Control and Cancer handbook group. He is a deputy theme lead within the Manchester NIHR Biomedical Research Centre and a member of various NIHR Research Collaboratives. He was previously a member of the Cochrane Collaborative Colorectal Cancer Group and a member of our colorectal cancer diagnosis and management guideline development group.

Professor Matt Stevenson BSc, PhD

Professor of health technology assessment, School of Health and Related Research, University of Sheffield

More about Matt

Matt studied operational research at Lancaster University where he received his doctorate. Matt has worked for the University of Sheffield for over 20 years where he has conducted cost-effectiveness analyses primarily for the National Institute for Health Research.

He is director of the School of Health and Related Research Technology Assessment Group, an academic group undertaking modelling work to provide data for our technology and diagnostic appraisals, and is additionally a member of our diagnostic advisory committee and also the NICE Decision Support Unit.

Professor Paul Tappenden

Reader in health economic modelling, ScHARR

More about Paul

Paul is a professor of health economic modelling at the School of Health and Related Research (ScHARR) within the University of Sheffield. Paul is the director of modelling for the ScHARR Technology Assessment Group.

Paul has an MSc in Health Services Research and Technology Assessment and a PhD on the role and value of “Whole Disease Models”, both awarded by the University of Sheffield. He has over 19 years' experience in designing, developing and appraising models. His primary research interest relates to the development and use of health economic models to inform decision-making.

Dr Derek Ward

Clinical senior lecturer in public health at the University of Birmingham

More about Derek

Dr Derek Ward is a clinical senior lecturer in public health at the University of Birmingham and an honorary consultant in public health with Public Health England.

Derek originally qualified in medicine and was appointed consultant in communicable disease control for the Health Protection Agency West Midlands in 2005. Subsequently, he worked as co-director of the NIHR Horizon Scanning Research and Intelligence Centre, where he developed a particular interest in new and emerging pharmaceuticals. At the University of Birmingham, Derek is the academic lead for assessment on the MBChB course, he leads a popular MPH programme and teaches across a broad range of programmes relevant to public health.

More information

Find out more about the committee and read papers from previous meetings.

About the technology appraisal committee


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