Find out more about the members of TAC C by reading their biographies.

Prof Stephen G O'Brien BSc (Hons) PhD MBChB FRCP MRCPath

Chair

Professor of Haematology at Newcastle University, Honorary Consultant Haematologist at Newcastle Hospitals NHS Foundation Trust

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Stephen is an academic clinician with an interest in leukaemia research. Following graduation and general medicine experience in Manchester he trained in haematology, completing a PhD in the molecular biology of leukaemia, at the Hammersmith Hospital in London.

He treated the first UK patients to receive imatinib and continues to be closely involved with ongoing trials of tyrosine kinase inhibitors in chronic myeloid leukaemia. As well as looking after NHS patients with haematological malignancies, Professor O’Brien is the Chief Investigator for the National Cancer Research Network’s SPIRIT trials in CML, involving over 1,000 patients in 150 UK hospitals and is a member of the NCRN Haem Onc Clinical Studies Group.


Dr Peter Selby

Vice Chair

Consultant Physician, Central Manchester University Hospitals NHS Foundation Trust

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Peter Selby is a consultant physician at the Manchester Royal Infirmary and Honorary Senior Lecturer in Medicine at the University of Manchester. After qualifying from Cambridge and Birmingham he undertook postgraduate training in endocrinology, diabetes and general medicine at Leeds and Newcastle before moving to Manchester in 1990. His main clinical and research field is endocrinology, especially disorders of calcium and bone metabolism.

He is currently chair of the Speciality Advisory Committee for training in Endocrinology and Diabetes and has previously been a trustee of the National Osteoporosis Society and the Paget's Association. In addition to his specialist work he remains active in general medicine and is clinical director for acute and rehabilitation medicine in the Manchester Royal Infirmary.


Kamal Balakrishnan

Orthopaedic Practitioner, Croydon Healthcare NHS Trust

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Kamal Balakrishnan qualified as a Physiotherapist in 1996. After qualifying, he undertook a PG Diploma in Musculoskeletal (MSK) Physiotherapy. He has specialised in MSK Physiotherapy over the last 22 years and has 9 years’ experience working as an Extended Scope Physiotherapist in MCATS (MSK Clinical Assessment and Triage Service) which is an interface service between the community and acute care. He has also completed an MSc in Health Management in Strategic Management and Leadership from City University, London.

Kamal is currently the Operations Clinical Lead – Adult Musculoskeletal Services, Croydon Health Services Health Services NHS Trust.


Dr Alex Cale


Mike Chambers

Director, MC Healthcare Evaluation

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With degrees in mathematical philosophy (University of Cambridge), demography (LSE) and health economics (University of York), Mike Chambers is currently founder and director of MC Healthcare Evaluation. From 2006 to 2015 he worked for GlaxoSmithKline as Director of Health Economics and latterly as Head of Reimbursement and Value Demonstration.

Previously he worked in the UK NHS (district information officer), at London Hospital Medical College (lecturer in department of epidemiology and medical statistics), MEDTAP International (contract research in economic evaluation) and as head of health economics at Amersham Health/GE Healthcare.

His main research interests have been in the development and application of principles of evidence-based medicine and in the methods and processes of health technology assessment, in particular the use of economic modelling and real world evidence to inform decision-making.


David Chandler

Lay member, PAPAA

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David Chandler has diverse experience, being involved in the voluntary sector since 1993. He has held the posts of coordinator of the Skin Care Campaign at the National Eczema Society, general manager at Teaching Aids at Low Cost, an international healthcare training and education NGO, Chief Executive of the Psoriasis Support Trust and also co-founded and jointly managed the Psoriatic Arthropathy Alliance with his wife Julie. During this time David has been a patient advocate, and given presentations on the patient perspective in Europe and the US, written and published articles, developed awareness campaigns and been involved in the development of both quantitative and qualitative research.

David is currently Chief Executive of PAPAA - The Psoriasis and Psoriatic Arthritis Alliance a UK patient charity. Prior to moving into healthcare advocacy he worked in commercial business. David is also involved in other committees as patient representative combining his own personal experience of having both psoriasis and psoriatic arthritis with that of those his charity represents. David also has a keen interest in social inclusion and equality issues.


Gail Coster

Advanced Practitioner Sonographer, Mid Yorkshire Hospitals NHS Trust

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Mrs Gail Coster works for Mid Yorkshire Hospitals NHS Trust. In 1978 she qualified as a diagnostic Radiographer and worked as both a clinical radiographer and as an ultrasonographer for 22 years. Throughout her professional career she has been a member of the College of Radiographers and the British Medical Ultrasound Society.

For the last 12 years she has worked in a managerial role which has involved elements of both operational management and the quality and governance agendas within health care. More recently she has undertaken a return into clinical practice at an advanced practice level where she is utilising both her management and clinical experience. Gail has worked with NICE as a member of the medical Technologies Advisory Committee and has worked with the Diagnostic Committee as a non-standing member for development of some guidance related to ultrasound. Being concerned about standards within Radiology Gail has worked on the review committee for the National Standards for Imagine Accreditation and also acts as an assessor for the scheme.


Dr Prithwiraj Das

Senior Health Economist, Boehringer Ingelheim Ltd

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Dr Prithwiraj Das trained as a medical doctor (MBBS, Gold Medallist, 2005) in India and worked as a House Surgeon at a centre of excellence in Paediatric Surgery in Delhi. He moved to the UK to pursue his Masters degree in International Health Policy from the London School Economics and Political Science (LSE).

Prithwiraj worked as a researcher at the LSE following his Masters, co-authoring a monograph for the World Health Organisation (WHO). He has also worked in niche commercial consulting for pharmaceutical market access in the UK and internationally. He has previously served as a standing member of our safe staffing committee.

Prithwiraj currently works as a Senior Health Economist and leads on UK market access for specialty medicines at Boehringer Ingelheim Limited.


Dr Natalie Hallas

Senior Health Economics and Commissioning Manager, Medtronic UK and Ireland

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Natalie is a Senior Health Economics and Commissioning Manager with over 10 years' experience in the medical device industry. Natalie completed her PhD in Cardiovascular Physiology at Brunel University alongside providing exercise physiology support to athletes, before joining Medtronic in 2006 as a Clinical Research Specialist. In this role she managed multi-centre clinical trials in various geographies including Australia and New Zealand.

Natalie holds a Postgraduate Diploma in Health Economics from the University of York, which she is now applying to her current role in relation to a range of medical technologies.


Mr John Hampson

Public Health Specialist, Cheshire West and Chester Council and lead for medicines management for the Cheshire and Merseyside Public Health Collaborative (Champs)

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John has been a Public Health Specialist since 2004 working in a Primary Care Trust (PCT) and latterly for the public health department of the local authority. He initially trained as a pharmacist and has over 20 years’ experience working in various hospitals in a variety of roles including formulary work, clinical pharmacy and in academia.

The main focus of his public health role is in evidence-based practice and involves critical appraisal of the literature for policy and strategy development at county and regional levels. As a registered pharmacist, he also provides medicines management advice to the public health departments in the local authorities of Cheshire and Merseyside.

Previous research interests have included antimicrobial therapy, diabetes and pharmacoepidemiology.


Dr Nigel Langford

Consultant Acute Physician and Clinical Pharmacologist

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Nigel Langford is a Consultant Acute Physician and Clinical Pharmacologist at Leicester Royal Infirmary, graduating from the Leicester Medical School in 1995. Prior to qualifying he had also worked as a pharmacist and retains membership of the Royal Pharmaceutical Society. He was awarded an MD in clinical pharmacology in 2005 from the University of Birmingham.

He has a long-standing interest in medical education, medical error and adverse drug reactions. He was a member of the NICE Guidelines Development Group for two guidelines looking at the prevention, identification and management of venous thromboembolic diseases. He is an honorary senior lecturer to the Leicester Medical School.


Dr Andrea Manca

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Andrea is a Senior Health Economist in the Centre for Health Economics at The University of York. His research interests focus on the application of statistical methods for the analysis of cost effectiveness and health outcomes data, and the use of quantitative evidence synthesis techniques to support healthcare decision making.

Andrea holds an MSc in Health Economics (1998) and a PhD in Economics (2005), both awarded by the University of York. He completed a post-doctoral fellowship in Health Services Research in 2007, awarded by The Wellcome Trust, and he is currently holding a Career Development Fellowship titled “Developing economic evaluation methods for decision making: the value of access to individual patient data” funded by the National Institute for Health Research (NIHR).

Andrea has evaluated health technologies in several clinical areas including breast and advanced colorectal cancer, endovascular aneurysm repair, coronary revascularisation, diabetes, neck and chronic low back pain, surgical interventions for urinary stress incontinence, and hysterectomy. He is co-editor of the journal Value in Health and senior associate editor of Pharmacoeconomics Italian Research Articles.


Dr Rubin Minhas

General Practitioner

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Rubin is a General Practitioner in Kent with an interest in cardiovascular disease, evidence-based decision making and its translation into clinical policy. He has served as both chair and member of the NICE guidelines for the primary and secondary prevention of cardiovascular disease committee. He was also an independent member of the NICE technology appraisals committee for 10 years.

He has been Editor-in-Chief of Clinical Evidence, Clinical Director of BMJ Evidence and served as Medical Director for Nuffield Health. He has supported several organisations, including chairing of the Cardiovascular Working Group of the South Asian Health Foundation, and was technical advisor to the National Prescribing Centre.

Rubin has co-authored textbooks and submissions to the House of Commons Health Select Committee, in addition to publications in medical journals. He holds a medical degree from the University of Leeds, an MBA from the University of Cambridge and was awarded a Harkness Fellowship which he undertook at the RAND Corporation in Los Angeles, USA.


Professor Andrew Renehan

Professor of Cancer Studies and Surgery


Dr Peter Selby

Consultant Physician, Central Manchester University Hospitals NHS Foundation Trust

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Peter Selby is a consultant physician at the Manchester Royal Infirmary and Honorary Senior Lecturer in Medicine at the University of Manchester. After qualifying from Cambridge and Birmingham he undertook postgraduate training in endocrinology, diabetes and general medicine at Leeds and Newcastle before moving to Manchester in 1990. His main clinical and research field is endocrinology, especially disorders of calcium and bone metabolism.

He is currently chair of the Speciality Advisory Committee for training in Endocrinology and Diabetes and has previously been a trustee of the National Osteoporosis Society and the Paget's Association. In addition to his specialist work he remains active in general medicine and is clinical director for acute and rehabilitation medicine in the Manchester Royal Infirmary.


Professor Matt Stevenson BSc, PhD

Professor of Health Technology Assessment, School of Health and Related Research, University of Sheffield

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Matt studied Operational Research at Lancaster University where he received his doctorate. Matt has worked for the University of Sheffield for over 20 years where he has conducted cost-effectiveness analyses primarily for the National Institute for Health Research.

He is Director of the School of Health and Related Research Technology Assessment Group, an academic group undertaking modelling work to provide data for NICE technology and diagnostic appraisals, and is additionally a member of NICE's technology appraisal committee and also the NICE Decision Support Unit.


Dr Paul Tappenden

Reader in Health Economic Modelling, ScHARR

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Paul Tappenden is a Reader in Health Economic Modelling at the School of Health and Related Research (ScHARR) within the University of Sheffield. Paul is the Deputy Technical Director of the ScHARR Technology Assessment Group. Paul is also a member of the NICE Decision Support Unit (DSU).

Paul has an MSc in Health Services Research and Technology Assessment and a PhD on the role and value of “Whole Disease Models”, both awarded by the University of Sheffield. He has over 10 years' experience in designing, developing and appraising models. His primary research interest relates to the development and use of health economic models to inform decision-making.


Professor Robert Walton BSc MD FRCP FRCGP DCH

Professor of Primary Care

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Robert Walton is a professor of primary care at Bart's and The London School of Medicine and Dentistry. His research interests include studying genetic differences that predispose to common illnesses and predict response to treatment. He holds an NIHR Programme grant to optimise therapy for smoking cessation and sits on the NIHR Research for Patient Benefit and Programme grant awarding committees.

Previously he was a senior lecturer in clinical pharmacology in Oxford and Head of Genetics at the Medical Research Council Laboratories in The Gambia, West Africa. Robert has been a general practitioner for 25 years in Oxford where he continues to practice.


Dr Derek Ward

Clinical Senior Lecturer in Public Health at the University of Birmingham

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Dr Derek Ward is a Clinical Senior Lecturer in Public Health at the University of Birmingham and an Honorary Consultant in Public Health with Public Health England.

Derek originally qualified in medicine and was appointed Consultant in Communicable Disease Control for the Health Protection Agency West Midlands in 2005. Subsequently, he worked as Co-Director of the NIHR Horizon Scanning Research & Intelligence Centre, where he developed a particular interest in new and emerging pharmaceuticals. At the University of Birmingham, Derek is the academic lead for assessment on the MBChB course, he leads a popular MPH programme and teaches across a broad range of programmes relevant to public health.


Dr Judith Wardle

Lay member

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Judith Wardle has had a varied career: 15 years as a university lecturer in English during which time she also studied music; 20 years as a singer/music teacher; and 16 years in the voluntary sector (the last 2 overlapped). Her move into the voluntary sector came after her son became disabled as a result of a road accident. The growing carers' movement in Oxfordshire drew on her talents for speaking, and clear writing and provided training in lobbying, and participation in multi-agency committees.

She chaired Oxfordshire Community Health Council at the same time as the Board of Trustees of the Children's Head Injury Trust. Her first paid post in the sector was as CEO of this charity and she later moved to the Continence Foundation. There she took a particular interest in integrated services: lecturing and publishing on the topic. She has served on various national committees, including contributing to the NSF for Long-Term Conditions and chairing the Patients Involved in NICE (PIN) Group from 2005-8. She is now retired.


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