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Showing 5596 to 5610 of 8314 results

  1. Phosphate binders: In adults with stage 4 or 5 CKD, including those on dialysis, what is the clinical and cost effectiveness and safety of long-term calcium acetate combined with magnesium carbonate for controlling serum phosphate?

    Recommendation ID NG203/17 Question Phosphate binders: In adults with stage 4 or 5 CKD, including those on dialysis, what is the clinical

    Research recommendation
    Published
    30 September 2021

  2. Indications for interventions – CT or MRI: In adults with asymptomatic severe tricuspid regurgitation what is the prognostic value and cost effectiveness of cardiac MRI for assessment of the right ventricle to assess the need for intervention?

    Recommendation ID NG208/11 Question Indications for interventions – CT or MRI: In adults with asymptomatic severe tricuspid regurgitation

    Research recommendation
    Published
    16 December 2021

  3. Anticoagulation and antiplatelet therapy: In adults with biological valve replacement, what effect does anticoagulation or antiplatelet therapy have on long-term valve function and outcomes?

    Recommendation ID NG208/23 Question Anticoagulation and antiplatelet therapy: In adults with biological valve replacement, what effect

    Research recommendation
    Published
    16 December 2021

  4. The effects of stopping and/or switching drug treatments to control blood glucose levels: In adults with type 2 diabetes, what are the effects of stopping and/or switching drug treatments to control blood glucose levels, and what criteria should inform the decision?

    Recommendation ID NG28/01 Question The effects of stopping and/or switching drug treatments to control blood glucose levels: In adults

    Research recommendation
    Published
    16 December 2021

  5. Long-term outcomes associated with blood glucose lowering agents: In adults with type 2 diabetes, what are the long‑term effects of blood glucose lowering therapies such as dipeptidyl peptidase‑4 (DPP‑4) inhibitors, sodium–glucose cotransporter‑2 (SGLT2) inhibitors and meglitinides?

    Recommendation ID NG28/04 Question Long-term outcomes associated with blood glucose lowering agents: In adults with type 2 diabetes, what

    Research recommendation
    Published
    16 December 2021

  6. Pilon fractures: In adults with closed pilon fractures, what method of fixation provides the best clinical and cost effectiveness outcomes as assessed by function and incidence of major complications at 2 years (stratified for timing of definitive surgery early [under 36 hours] versus later [over 36 hours])?

    Recommendation ID NG37/03 Question Pilon fractures: In adults with closed pilon fractures, what method of fixation provides the best clinical

    Research recommendation
    Published
    12 December 2022

  7. In adults with common bile duct stones, should laparoscopic cholecystectomy be performed early (within 2 weeks of bile duct clearance), or should it be delayed (until 6 weeks after bile duct clearance)?

    Recommendation ID CG188/4 Question In adults with common bile duct stones, should laparoscopic cholecystectomy be performed early (within

    Research recommendation
    Published
    9 June 2015

  8. Non-metformin-based drug treatment combinations to control blood glucose levels: In adults with type 2 diabetes, what treatment combinations (for example, glucagon‑like peptide‑1 [GLP‑1] mimetics and insulin combination therapy with meglitinides) are most effective when initial drug treatment with non‑metformin monotherapy fails to adequately control blood glucose levels?

    Recommendation ID NG28/02 Question Non-metformin-based drug treatment combinations to control blood glucose levels: In adults with type

    Research recommendation
    Published
    16 December 2021

  9. Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative vision- and health-related quality of life, and postoperative vision-related quality of life, health-related quality of life, and self-reported postoperative improvement?

    Recommendation ID NG77/3 Question Indicators and thresholds for referral for cataract surgery:- What is the association between preoperative

    Research recommendation
    Published
    6 November 2018

  10. Individual versus group CBT for children and young people with social anxiety disorder:- What is the clinical and cost effectiveness of individual and group CBT for children and young people with social anxiety disorder?

    Recommendation ID CG159/4 Question Individual versus group CBT for children and young people with social anxiety disorder:- What is the

    Research recommendation
    Published
    9 June 2015

  11. What is the clinical and cost effectiveness of prednisolone compared with aminosalicylates for the induction of remission for people with moderate ulcerative colitis?

    Recommendation ID NG130/4 Question What is the clinical and cost effectiveness of prednisolone compared with aminosalicylates for the induction

    Research recommendation
    Published
    25 October 2019

  12. What is the clinical and cost effectiveness of prednisolone plus an aminosalicylate compared with beclometasone plus an aminosalicylate for induction of remission for people with moderate ulcerative colitis?

    Recommendation ID NG130/5 Question What is the clinical and cost effectiveness of prednisolone plus an aminosalicylate compared with beclometasone

    Research recommendation
    Published
    25 October 2019

  13. What are the benefits, risks and cost effectiveness of methotrexate, ciclosporin, tacrolimus, adalimumab and infliximab compared with each other and with placebo for induction of remission for people with subacute ulcerative colitis that is refractory to systemic corticosteroids?

    Recommendation ID NG130/6 Question What are the benefits, risks and cost effectiveness of methotrexate, ciclosporin, tacrolimus, adalimumab

    Research recommendation
    Published
    25 October 2019

  14. Further research is recommended on alternative postpartum testing strategies that do not include cord blood typing of all babies born to rhesus-D (D) negative women.

    Recommendation ID DG25/1 Question Further research is recommended on alternative postpartum testing strategies that do not include cord

    Research recommendation
    Published
    10 February 2017

  15. Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER, IDKmonitor and Promonitor) in people whose Crohn's disease is losing response to a TNF-alpha inhibitor. This could be through a prospective study, for local audit, or for submission to a registry. (The IBD Registry is being adapted to receive data on TNF-alpha inhibitor levels and antibodies against TNF-alpha inhibitors).

    Recommendation ID DG22/2 Question Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER

    Research recommendation
    Published
    21 March 2016