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This manual explains the processes and methods used to develop and update NICE guidelines, the guidance that NICE develops covering topics across clinical care (in primary, secondary and community care settings), social care and public health. For more information on the other types of NICE guidance and advice (including technology appraisal guidance), see about NICE
Disease-specific reference case extension: management of overweight and obesity in adults (PMG50)
This NICE disease-specific reference case extension describes standardised methods for health economic evaluations of interventions for managing overweight and obesity in adults. For further details on developing and implementing disease-specific reference case extensions, see NICE’s position statement on use of disease-specific reference models in economic evaluations
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This manual sets out the process for how new guidance topics and updates to existing NICE guidance are identified, prioritised and routed at NICE, and the decision-making framework used by the NICE prioritisation board
Home Implementing NICE guidance Social care Using NICE guidance in social work: scenarios for principle social workers Principle social workers -...
Agenda and papers of the NICE public board meeting on 20 May 2025
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NICE is committed to supporting the national agenda for achieving a sustainable health and care system.
Read NICE's statement on modern slavery and human trafficking.
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Evidence-based recommendations on living-donor liver transplantation. This involves replacing a diseased or damaged liver with a healthy one from a living human donor.
Evidence-based recommendations on artificial anal sphincter implantation. This involves placing a circular cuff under the skin around the anus.
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Sections for HTG39