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NICE is unable to make a recommendation on semaglutide (Wegovy) for managing overweight and obesity in young people aged 12 to 17 years because Novo Nordisk did not provide an evidence submission. We will review this decision if the company decides to make a submission.
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Sections for TA910
Study NICE and LSE's Executive MSc Healthcare Decision-Making
Study NICE and LSE's Executive MSc Healthcare Decision-Making
Apply to the bursary scheme to find out more about how NICE is focusing on what matters most to the health and care system and delivering useful and usable advice, when and where it is most needed.
Lorlatinib for untreated ALK-positive advanced non-small-cell lung cancer (TA909)
Evidence-based recommendations on lorlatinib (Lorviqua) for untreated ALK-positive advanced non-small-cell lung cancer in adults.
This guidance evaluates new, innovative diagnostic technologies. It includes all types of measurements and tests that are used to evaluate a patient's
Recommendation ID DG53/1 Question Further research is recommended to determine the impact of MRI fusion biopsy systems compared with cognitive
Recommendation ID DG53/2 Question Further data collection or research is recommended on the impact of implementing MRI fusion biopsy systems
Recommendation ID DG52/3 Question The committee recommends collecting further data on clinical outcomes such as time to healing, and incorrect
Recommendation ID DG52/2 Question The committee recommends collecting further data on the impact of the automated devices on time to treatment
Recommendation ID DG52/1 Question The committee recommends more research on diagnostic accuracy in people with leg ulcers. The following
Help for care home managers and staff to prevent infection
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This quality standard covers identifying and supporting adults and young people (aged 10 and over) who may have an alcohol-use disorder and caring for people with alcohol-related health problems, as well as support for their families and carers. It describes high-quality care in priority areas for improvement.
View quality statements for QS11Show all sections
Sections for QS11
- Quality statements
- Quality statement 1: Use of validated alcohol questionnaires
- Quality statement 2: Community support networks and self-help groups
- Quality statement 3: Triage assessment in specialist alcohol services
- Quality statement 4: Acute alcohol withdrawal
- Quality statement 5: Interventions to prevent relapse after unplanned withdrawal from alcohol in hospital
- Update information
- About this quality standard
Evidence-based recommendations on AI-derived computer-aided detection (CAD) software for detecting and measuring lung nodules in CT scan images
Doctors have been advised to offer people with signs or symptoms of colorectal cancer a home test to reduce the waiting times for a colonoscopy, NICE has said in draft guidance.
Irreversible electroporation for treating prostate cancer (IPG768)
Evidence-based recommendations on irreversible electroporation for treating prostate cancer. This involves using electrical pulses to destroy the cancer cells.
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Evidence-based recommendations on rimegepant (Vydura) for preventing migraine in adults.
Evidence-based recommendations on olaparib (Lynparza) for maintenance treatment of relapsed, platinum-sensitive ovarian, fallopian tube or peritoneal cancer after 2 or more courses of platinum-based chemotherapy in adults.
Dr Sam Roberts, chief executive of NICE, celebrates the NHS on its 75th anniversary. She discusses how NICE has supported the NHS with its recent achievements. She also highlights how NICE is evolving; through driving value-based healthcare to support the NHS as it adapts to meet current challenges.
Learn from NICE International, part of the UK’s National Institute for Health and Care Excellence, about how to improve your nation’s health and wellbeing
Ask an expert from NICE International, part of the UK’s National Institute for Health and Care Excellence, to speak at a healthcare event in your country
Oesophago-gastric cancer: assessment and management in adults (NG83)
This guideline covers assessing and managing oesophago-gastric cancer in adults, including radical and palliative treatment and nutritional support. It aims to reduce variation in practice through better organisation of care and support, and improve quality of life and survival by giving advice on the most suitable treatments depending on cancer type, stage and location.
This agreement relates to treating cystic fibrosis patients with: Ivacaftor, tezacaftor and elexacaftor (Kaftrio®) in combination with ivacaftor for
Position statement on use of the EQ-5D-5L value set for England (updated October 2019)
Our position on use of the EQ-5D-5L valuation set for England
It takes 38 weeks to develop a piece of medical technologies guidance. Timings are approximate and may change for some topics. The Medical...
This quality standard covers the clinical assessment and management of depression in adults aged 18 and over. It describes high-quality care in priority areas for improvement.
View quality statements for QS8Show all sections
Sections for QS8
- Quality statements
- Quality statement 1: Assessment
- Quality statement 2: Discussing treatment options
- Quality statement 3: Preventing relapse
- Quality statement 4: Stopping antidepressants
- Quality statement 5: Access to services for adults from minority ethnic backgrounds
- Update information
- About this quality standard
A step-by-step timeline of the process we used to develop single technology appraisals (STA)
Evidence-based recommendations on botulinum toxin type A injections into the urethral sphincter for idiopathic chronic non-obstructive urinary retention. This involves injecting botulinum toxin type A into the urethral sphincter.
View recommendations for IPG766Show all sections
Radiofrequency denervation for osteoarthritic knee pain (IPG767)
Evidence-based recommendations on radiofrequency denervation for osteoarthritic knee pain. This involves applying heat (radiofrequency) energy to damage the nerves (denervation) that are causing pain in the knee.
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Find out more about the progress made in implementing NICE guidance on diagnostic pathology
Deucravacitinib for treating moderate to severe plaque psoriasis (TA907)
Evidence-based recommendations on deucravacitinib for treating moderate to severe plaque psoriasis in adults.
More evidence needed to recommend Type 2 diabetes treatment tirzepatide
More evidence is needed on the clinical and cost-effectiveness of a new treatment option for people with type 2 diabetes before it could be recommended for NHS use, a NICE committee has said.
NICE launches public consultation on updates to health technology evaluations manual
A public consultation on updates to NICE's health technology evaluations manual is now open.
Dr Sam Roberts has been outlining the changes underway at NICE to meet the challenges of a rapidly evolving health technology sector and patient expectations
Evidence-based recommendations on endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis when surgery is not an option. This involves inserting a stent through an endoscope into the gallbladder.
View recommendations for IPG764Show all sections
Evidence-based recommendations on minimally invasive fusionless posterior-approach surgery to correct idiopathic scoliosis in children and young people. This involves inserting a rod along the spine through a small cut in the back.
View recommendations for IPG765Show all sections
Recommendation ID IPG653/1 Question Current evidence on the safety and efficacy of valve-in-valve transcatheter aortic valve implantation
With your help, we're improving outcomes for people who use the NHS and other public health and social care services. Find out how you can get...
Evidence-based recommendations on dapagliflozin (Forxiga) for treating chronic heart failure with preserved or mildly reduced ejection fraction in adults.
Evidence-based recommendations on darolutamide (Nubeqa) with androgen deprivation therapy and docetaxel for hormone-sensitive metastatic prostate cancer in adults.
Evidence-based recommendations on pembrolizumab (Keytruda) with lenvatinib (Lenvima) for treating advanced or recurrent endometrial cancer in adults.
Upadacitinib for previously treated moderately to severely active Crohn's disease (TA905)
Evidence-based recommendations on upadacitinib (Rinvoq) for previously treated moderately to severely active Crohn’s disease in adults.
Your experiences are vital to the development of our guidance, standards and advice. We're committed to involving people who use services, carers and
Cemiplimab for treating recurrent or metastatic cervical cancer (terminated appraisal) (TA901)
NICE is unable to make a recommendation on cemiplimab (Libtayo) for treating recurrent or metastatic cervical cancer in adults because Sanofi did not provide an evidence submission. We will review this decision if the company decides to make a submission.
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Sections for TA901
Find out more about the types of organisations that can register to be a stakeholder at NICE.
NICE has developed a medtech innovation briefing (MIB) on MiraQ cardiac TTFM with high-frequency probe for assessing graft flow during coronary artery bypass graft surgery .
We've updated our health inequalities web resource so that it maps NICE guidance to frameworks for children and young people. Dr Clare Morgan, director of implementation and partnerships explains how you can use the resource to ensure you're delivering effective care.
Patient decision aid on medicines associated with dependence or withdrawal symptoms published
All forms of inflammatory arthritis have similar management strategies coordinated through a multidisciplinary team. Pharmacological treatments are...