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Guidance programme

Advice programme

Showing 5251 to 5300 of 8238 results

  1. What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non‑small‑cell lung cancer following multimodality treatment including surgery?

    Recommendation ID NG122/01 Question What is the effectiveness and cost effectiveness of immunotherapy in people with stage IIIA-N2 non‑small‑cell

  2. What are the emission profiles of indoor air pollutants released from building materials in a lived-in home environment?

    Recommendation ID NG149/4 Question What are the emission profiles of indoor air pollutants released from building materials in a lived-in

  3. What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic pain?

    Recommendation ID CG173/5 Question What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic

  4. Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of  research .

    Recommendation ID IPG660/1 Question Current evidence on the safety and efficacy of implant insertion for prominent ears is inadequate in

  5. Impact of drug-related adverse effects on cost effectiveness and quality of life:- What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic pain?

    Recommendation ID CG173/5 Question Impact of drug-related adverse effects on cost effectiveness and quality of life:- What is the impact

  6. Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies to improve medicines adherence in adults, young people and children with asthma who are non-adherent to prescribed medicines?

    Recommendation ID NG80/10 Question Improving adherence to asthma medication:- What are the most clinically and cost-effective strategies

  7. Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does enhanced developmental support and surveillance improve outcomes for the parents and carers of children born preterm?

    Recommendation ID NG72/5 Question Impact of enhanced developmental support and surveillance for children born preterm on parents and carers:- Does

  8. Improving consent rates:- What are the key components of an intervention to improve consent rates?

    Recommendation ID CG135/4 Question Improving consent rates:- What are the key components of an intervention to improve consent rates?

  9. What effects does isolation have on the quality of life of people being treated for TB?

    Recommendation ID NG33/4 Question What effects does isolation have on the quality of life of people being treated for TB? Any explanatory

  10. Improving rates of identification and referral of potential donors:- What are the key components of an intervention to improve identification and referral rates?

    Recommendation ID CG135/3 Question Improving rates of identification and referral of potential donors:- What are the key components of

  11. Impact of risk-reducing surgery:- Further research is recommended to compare psychosocial and clinical outcomes in women who choose and women who do not choose to have risk-reducing surgery. [new 2013]

    Recommendation ID CG164/5 Question Impact of risk-reducing surgery:- Further research is recommended to compare psychosocial and clinical

  12. Thresholds for interventions in adults aged under 40: In adults aged under 40 with hypertension (with or without type 2 diabetes), what are the appropriate risk and blood pressure thresholds for starting treatment?

    Recommendation ID NG136/02 Question Thresholds for interventions in adults aged under 40: In adults aged under 40 with hypertension (with

  13. For which people with impetigo are antiseptics as effective as antibiotics?

    Recommendation ID NG153/1 Question For which people with impetigo are antiseptics as effective as antibiotics? Any explanatory notes(if

  14. Creatinine-based estimate of eGFR – existing calculations: In adults, children and young people from black, Asian and other minority ethnic groups with chronic kidney disease (CKD) living in the UK, which existing eGFR calculations are the most accurate?

    Recommendation ID NG203/1 Question Creatinine-based estimate of eGFR – existing calculations: In adults, children and young people from

  15. Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears should address patient selection, type of graft and technique used,long-term outcomes including shoulder function, and patient-reported outcome measures.

    Recommendation ID IPG619/1 Question Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears

  16. Research should be carried out to compare the clinical effectiveness of bendamustine with chlorambucil at the higher dose used in the Chronic Lymphocytic Leukaemia Trial 4 (CLL4).

    Recommendation ID TA216/1 Question Research should be carried out to compare the clinical effectiveness of bendamustine with chlorambucil

  17. How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis or gangrene) be reviewed?

    Recommendation ID NG19/8 Question How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis

  18. What clinical features and laboratory investigations can be used to better stratify risk for women in labour with signs of sepsis (including fever and tachycardia)?

    Recommendation ID NG121/4 Question What clinical features and laboratory investigations can be used to better stratify risk for women in

  19. Risk assessment in neonates, infants, children and young people:- Which pressure ulcer tools are most effective for predicting pressure ulcer risk in children?

    Recommendation ID CG179/3 Question Risk assessment in neonates, infants, children and young people:- Which pressure ulcer tools are most

  20. What are the risk factors for diverticulosis progressing to diverticular disease?

    Recommendation ID NG147/6 Question What are the risk factors for diverticulosis progressing to diverticular disease? Any explanatory

  21. Refractory [Irritable bowel syndrome] (IBS):- What factors contribute to refractory IBS?

    Recommendation ID CG61/3 Question Refractory [Irritable bowel syndrome] (IBS):- What factors contribute to refractory IBS? Any explanatory

  22. Rehabilitation: - What are the barriers to people with major trauma receiving early rehabilitation after rehabilitation assessment? What changes to services are needed to overcome these barriers?

    Recommendation ID NG40/2 Question Rehabilitation: - What are the barriers to people with major trauma receiving early rehabilitation after

  23. Is response to pharmacological treatment predicted more reliably by underlying aetiology or by symptom characteristics?

    Recommendation ID CG173/2 Question Is response to pharmacological treatment predicted more reliably by underlying aetiology or by symptom

  24. Relationship between symptoms, cause of neuropathic pain and its treatment:- Is response to pharmacological treatment predicted more reliably by underlying aetiology or by symptom characteristics?

    Recommendation ID CG173/2 Question Relationship between symptoms, cause of neuropathic pain and its treatment:- Is response to pharmacological

  25. Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness and cost effectiveness of the KEEP intervention for foster carersof abused or neglected children compared to other interventions?

    Recommendation ID NG76/15 Question Relative effectiveness of interventions to support foster carers:- What is the relative effectiveness

  26. Relaxation and biofeedback:- What is the effect of relaxation and biofeedback therapies on [Irritable bowel syndrome] (IBS) symptoms and patient-related outcomes?

    Recommendation ID CG61/4 Question Relaxation and biofeedback:- What is the effect of relaxation and biofeedback therapies on [Irritable

  27. Remote decision-support technologies:- Are paramedic remote decision-support technologies clinically and cost effective? [See the evidence review on paramedic remote support.]

    Recommendation ID NG94/7 Question Remote decision-support technologies:- Are paramedic remote decision-support technologies clinically

  28. Repositioning:- When repositioning a person who is at risk of developing a pressure ulcer, what is the most effective position – and optimum frequency of repositioning – to prevent a pressure ulcer developing?

    Recommendation ID CG179/5 Question Repositioning:- When repositioning a person who is at risk of developing a pressure ulcer, what is the

  29. Research into the long-term treatment effects of rivaroxaban is needed.

    Recommendation ID TA287/2 Question Research into the long-term treatment effects of rivaroxaban is needed. Any explanatory notes(if

  30. Research is needed on the impact of treating Alzheimer's disease on mortality and institutionalisation, and to assess the relationship between disease progression and carer utility (quality of life).

    Recommendation ID TA217/2 Question Research is needed on the impact of treating Alzheimer's disease on mortality and institutionalisation

  31. Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's disease on both short-term and long-term outcomes, disease progression through relevant health states, and quality of life.

    Recommendation ID TA217/1 Question Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's

  32. Service delivery models:- Which models of service delivery are effective and cost-effective for older people with social care needs and multiple long-term conditions?

    Recommendation ID NG22/2 Question Service delivery models:- Which models of service delivery are effective and cost-effective for older

  33. Service provision for neutropenic sepsis in patients with cancer:- A prospective national cohort study should be carried out to assess the incidence of suspected and proven neutropenic sepsis in patients having anticancer treatment.

    Recommendation ID CG151/1 Question Service provision for neutropenic sepsis in patients with cancer:- A prospective national cohort study

  34. Aspirin treatment in acute ischaemic stroke: Should a person who has a stroke or a TIA and is already taking aspirin be prescribed the same or an increased dose of aspirin after the stroke?

    Recommendation ID NG128/06 Question Aspirin treatment in acute ischaemic stroke: Should a person who has a stroke or a TIA and is already

  35. What staff training interventions are effective at facilitating personal recovery for people with complex psychosis?

    Recommendation ID NG181/7 Question What staff training interventions are effective at facilitating personal recovery for people with complex

  36. Signs and symptoms that predict neutropenic sepsis in the community:- A prospective study should be carried out to determine which signs and symptoms experienced by patients in the community predict neutropenic sepsis and the outcomes of these episodes.

    Recommendation ID CG151/3 Question Signs and symptoms that predict neutropenic sepsis in the community:- A prospective study should be

  37. What is the effectiveness of age alone and other routinely available risk factors compared with the formal structured multifactorial risk assessment to identify people at high risk of developing CVD?

    Recommendation ID NG238/1 Question What is the effectiveness of age alone and other routinely available risk factors compared with the

  38. What is the most clinically and cost-effective timing and dose of a single administration of gabapentin to relieve pain in people undergoing surgery whose pain is expected to be moderate to severe?

    Recommendation ID NG180/7 Question What is the most clinically and cost-effective timing and dose of a single administration of gabapentin

  39. Standard principles of infection prevention and control:- What are the barriers to compliance with the standard principles of infection prevention and control that patients and carers experience in their own homes?

    Recommendation ID CG139/1 Question Standard principles of infection prevention and control:- What are the barriers to compliance with the

  40. What skin care advice is appropriate for people with acne?

    Recommendation ID NG198/4 Question What skin care advice is appropriate for people with acne? Any explanatory notes(if applicable)

  41. Reducing use of emergency dental care:- What interventions are effective and cost effective at encouraging people who usually only go to emergency dental services to use general dental services regularly, in a bid to improve their oral health?

    Recommendation ID NG30/2 Question Reducing use of emergency dental care:- What interventions are effective and cost effective at encouraging

  42. When and with what criteria should people with diabetes be referred to the foot protection service or the multidisciplinary foot care service?

    Recommendation ID NG19/2 Question When and with what criteria should people with diabetes be referred to the foot protection service or

  43. Referral criteria for the foot protection service and the multidisciplinary foot care service:- When and with what criteria should people with diabetes be referred to the foot protection service or the multidisciplinary foot care service?

    Recommendation ID NG19/2 Question Referral criteria for the foot protection service and the multidisciplinary foot care service:- When

  44. Referral filtering:- What is the effectiveness and cost effectiveness of the different models for glaucoma filtering (pathways from case-finding to assessment in secondary ophthalmic care) for detecting glaucoma and glaucoma-related conditions (ocular hypertension and suspected glaucoma)?

    Recommendation ID NG81/5 Question Referral filtering:- What is the effectiveness and cost effectiveness of the different models for glaucoma