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Showing 701 to 750 of 4091 results for patient

  1. Cetuximab and panitumumab for previously untreated metastatic colorectal cancer (TA439)

    Evidence-based recommendations on cetuximab (Erbitux) and panitumumab (Vectibix) for previously untreated RAS wild-type metastatic colorectal cancer in adults.

    Technology appraisal guidance
    Last updated
    25 September 2017
    View recommendations

    Sections for TA439

  2. Further research on the safety of unilateral MRI-guided focused ultrasound thalamotomy for treatment-resistant essential tremor, which could include randomised controlled trials, should address patient selection, report on functional improvement and quality of life, and provide long-term follow-up data.

    tremor, which could include randomised controlled trials, should address patient selection, report on functional improvement and quality...

    Research recommendation
    Published
    10 December 2018

  3. Baricitinib for treating moderate to severe atopic dermatitis (TA681)

    Evidence-based recommendations on baricitinib for treating moderate to severe atopic dermatitis in adults.

    Technology appraisal guidance
    Published
    3 March 2021
    View recommendations

    Sections for TA681

  4. Virtual compared with face-to-face clinics:- What is the clinical and cost effectiveness of virtual new patient fracture clinics compared with next-day consultant-led face-to-face clinics in people presenting with non-complex fractures in the emergency department and thought to need an orthopaedic opinion?

    face-to-face clinics:- What is the clinical and cost effectiveness of virtual new patient fracture clinics compared with next-day...

    Research recommendation
    Published
    21 March 2016

  5. Filgotinib for treating moderate to severe rheumatoid arthritis (TA676)

    Evidence-based recommendations on filgotinib (Jyseleca) for moderate to severe rheumatoid arthritis in adults.

    Technology appraisal guidance
    Published
    24 February 2021
    View recommendations

    Sections for TA676

  6. HumiGard for preventing inadvertent perioperative hypothermia (HTG428)

    Evidence-based recommendations on HumiGard for preventing inadvertent perioperative hypothermia.

    HealthTech guidance
    Published
    8 February 2017
    View recommendations

    Sections for HTG428

  7. Transoral carbon dioxide laser surgery for primary treatment of oropharyngeal malignancy (HTG337)

    Evidence-based recommendations on transoral carbon dioxide laser surgery for primary treatment of oropharyngeal malignancy. This involves using a laser to cut out the tumour and a small amount of the healthy flesh around it.

    HealthTech guidance
    Published
    27 March 2014
    View recommendations

    Sections for HTG337

  8. Irreversible electroporation for primary liver cancer (HTG532)

    Evidence-based recommendations on irreversible electroporation for primary liver cancer in adults. This involves passing short electrical pulses of high-voltage current into the cancer cells.

    HealthTech guidance
    Published
    27 November 2019
    View recommendations

    Sections for HTG532

  9. Reducing antimicrobial resistance:- What interventions, systems and processes are effective and cost effective in reducing antimicrobial resistance without causing harm to patients?

    effective in reducing antimicrobial resistance without causing harm to patients? Any explanatory notes(if applicable) Recommendation:-...

    Research recommendation
    Published
    12 October 2015

  10. Tacrolimus and pimecrolimus for atopic eczema (TA82)

    Evidence-based recommendations on tacrolimus (Protopic) and pimecrolimus (Elidel) for people with atopic eczema.

    Technology appraisal guidance
    Published
    25 August 2004
    View recommendations

    Sections for TA82

  11. Focal therapy using cryoablation for localised prostate cancer (HTG284)

    Evidence-based recommendations on focal therapy using cryoablation for localised stage prostate cancer. This involves using freezing (cryotherapy) needles to find and destroy only the cancerous part of the prostate.

    HealthTech guidance
    Published
    26 April 2012
    View recommendations

    Sections for HTG284

  12. Further research into endoscopic radiofrequency therapy of the anal sphincter for faecal incontinence should clearly define the patient groups being treated. It should also report the clinical impact in terms of quality of life and long-term outcomes. NICE may review the procedure on publication of further evidence.

    of the anal sphincter for faecal incontinence should clearly define the patient groups being treated. It should also report the clinical...

    Research recommendation
    Published
    9 June 2015

  13. Sparsentan for treating primary IgA nephropathy (TA1074)

    Evidence-based recommendations on sparsentan (Filspari) for treating primary immunoglobulin A (IgA) nephropathy in adults.

    Technology appraisal guidance
    Last updated
    9 October 2025
    View recommendations

    Sections for TA1074

  14. Continuous subcutaneous insulin infusion for the treatment of diabetes mellitus (TA151)

    Evidence-based recommendations on continuous subcutaneous insulin infusion (insulin pump therapy) for treating type 1 diabetes in adults and children.

    Technology appraisal guidance
    Published
    23 July 2008
    View recommendations

    Sections for TA151

  15. Current evidence on the safety and efficacy of irreversible electroporation for treating liver metastases is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research. In particular, studies should report the effect of the procedure on local tumour control and patient survival.

    studies should report the effect of the procedure on local tumour control and patient survival. Any explanatory notes(if applicable)...

    Research recommendation
    Published
    9 June 2015

  16. Current evidence on the safety and efficacy of irreversible electroporation for treating renal cancer is inadequate in quantity and quality. Therefore, this procedure should only be used in the context of research. In particular, studies should report the effect of the procedure on local tumour control and patient survival.

    studies should report the effect of the procedure on local tumour control and patient survival. Any explanatory notes(if applicable)...

    Research recommendation
    Published
    9 June 2015

  17. The Debrisoft monofilament debridement pad for use in acute or chronic wounds (HTG334)

    Evidence-based recommendations on the Debrisoft monofilament debridement pad for use in acute or chronic wounds.

    HealthTech guidance
    Last updated
    25 March 2019
    View recommendations

    Sections for HTG334

  18. Eating disorders (QS175)

    This quality standard covers assessment, treatment, monitoring and care for children, young people and adults with an eating disorder. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    21 September 2018
    View quality statements

    Sections for QS175

  19. Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolism (TA341)

    Evidence-based recommendations on apixaban (Eliquis) for treating and preventing recurrent deep vein thrombosis or pulmonary embolism in adults.

    Technology appraisal guidance
    Published
    4 June 2015
    View recommendations

    Sections for TA341

  20. Transapical transcatheter mitral valve-in-ring implantation after failed annuloplasty for mitral valve repair (HTG593)

    Evidence-based recommendations on transapical transcatheter mitral valve-in-ring implantation after failed annuloplasty for mitral valve repair in adults. This involves inserting a bioprosthetic mitral valve into an existing mitral valve ring to treat a leaking mitral valve, without needing repeat open heart surgery.

    HealthTech guidance
    Published
    22 September 2021
    View recommendations

    Sections for HTG593

  21. Dapagliflozin for treating chronic heart failure with reduced ejection fraction (TA679)

    Evidence-based recommendations on dapagliflozin (Forxiga) for symptomatic chronic heart failure with reduced ejection fraction in adults.

    Technology appraisal guidance
    Published
    24 February 2021
    View recommendations

    Sections for TA679

  22. Prostate cancer: diagnosis and management (NG131)

    This guideline covers the diagnosis and management of prostate cancer in secondary care, including information on the best way to diagnose and identify different stages of the disease, and how to manage adverse effects of treatment. It also includes recommendations on follow-up in primary care for people diagnosed with prostate cancer.

    NICE guideline
    Last updated
    15 December 2021
    View recommendations

    Sections for NG131

  23. Guidance on the use of trastuzumab for the treatment of advanced breast cancer (TA34)

    Evidence-based recommendations on trastuzumab for treating advanced breast cancer in adults.

    Technology appraisal guidance
    Published
    15 March 2002
    View recommendations

    Sections for TA34

  24. NICE noted that the cost effectiveness of lenalidomide compared with standard care for people with low- or intermediate-1-risk MDS associated with an isolated deletion 5q cytogenetic abnormality when other therapeutic options are insufficient or inadequate, was sensitive to whether the patient access scheme would be realised in clinical practice. The Committee agreed that it would be critical to generate evidence to support the following: - The proportion of people who become eligible for the patient access scheme, that is, that they remain on treatment beyond 26 cycles. - The benefit of lenalidomide after 26 cycles, that is the associated overall survival and health related quality of life for those who remain on treatment beyond 26 cycles.

    therapeutic options are insufficient or inadequate, was sensitive to whether the patient access scheme would be realised in clinical...

    Research recommendation
    Published
    9 June 2015

  25. Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated (TA377)

    Evidence-based recommendations on enzalutamide (Xtandi) for treating metastatic, hormone-relapsed prostate cancer for people in whom chemotherapy is not yet clinically indicated.

    Technology appraisal guidance
    Published
    27 January 2016
    View recommendations

    Sections for TA377

  26. Commercial access agreements

    The NICE commercial liaison team aim to reduce the workload for the NHS and frontline staff by making commercial agreements more straightforward.

  27. Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by motor neurone disease (HTG450)

    Evidence-based recommendations on intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure in people with motor neurone disease. This involves implanting electrodes into the diaphragm to make it contract. This gradually strengthens the diaphragm and may eventually help the person to breathe without a ventilator.

    HealthTech guidance
    Published
    27 September 2017
    View recommendations

    Sections for HTG450

  28. Warming in patients with major trauma:- Is warming clinically and cost effective in patients with major trauma? If so, which groups of patients will benefit from warming and what is the best method of warming?

    Warming in patients with major trauma:- Is warming clinically and cost effective in patients with major trauma? If so,...

    Research recommendation
    Published
    21 March 2016

  29. Non-rigid stabilisation techniques for the treatment of low back pain (HTG239)

    Evidence-based recommendations on non-rigid stabilisation techniques for the treatment of low back pain. This involves joining the problem bones together using a non-rigid implant between 2 or more vertebrae.

    HealthTech guidance
    Published
    24 November 2010
    View recommendations

    Sections for HTG239

  30. Barnett Continent Intestinal Reservoir (modified continent ileostomy) to restore continence after colon and rectum removal (HTG503)

    Evidence-based recommendations on Barnett Continent Intestinal Reservoir (modified continent ileostomy) to restore continence after colon and rectum removal in adults. This involves using the ileum to create a pouch on the inside of the abdominal wall to collect waste.

    HealthTech guidance
    Published
    20 February 2019
    View recommendations

    Sections for HTG503

  31. Irreversible electroporation for treating primary lung cancer and metastases in the lung (HTG302)

    Evidence-based recommendations on irreversible electroporation for treating primary lung cancer and metastases in the lung. This involves using electrical pulses to kill cancer cells.

    HealthTech guidance
    Published
    23 February 2013
    View recommendations

    Sections for HTG302

  32. Chlormethine gel for treating mycosis fungoides-type cutaneous T-cell lymphoma (TA720)

    Evidence-based recommendations on chlormethine gel (Ledaga) for treating early-stage mycosis fungoides-type cutaneous T-cell lymphoma in adults.

    Technology appraisal guidance
    Published
    18 August 2021
    View recommendations

    Sections for TA720

  33. Atrial fibrillation: diagnosis and management (NG196)

    This guideline covers diagnosing and managing atrial fibrillation in adults. It includes guidance on providing the best care and treatment for people with atrial fibrillation, including assessing and managing risks of stroke and bleeding.

    NICE guideline
    Last updated
    30 June 2021
    View recommendations

    Sections for NG196

  34. Artificial iris insertion for acquired aniridia (HTG546)

    Evidence-based recommendations on artificial iris insertion for acquired aniridia. This involves inserting an artificial iris into the eye.

    HealthTech guidance
    Published
    22 July 2020
    View recommendations

    Sections for HTG546

  35. Evidence on the safety of endoluminal gastroplication for gastro-oesophageal reflux disease is adequate. However, evidence on its efficacy is inadequate in quality, particularly in terms of patient selection and long-term outcomes. Therefore, this procedure should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    evidence on its efficacy is inadequate in quality, particularly in terms of patient selection and long-term outcomes. Therefore, this...

    Research recommendation
    Published
    27 April 2023

  36. Transapical transcatheter mitral valve-in-valve implantation for a failed surgically implanted mitral valve bioprosthesis (HTG592)

    Evidence-based recommendations on transapical transcatheter mitral valve-in-valve implantation for a failed surgically implanted mitral valve bioprosthesis in adults. This involves inserting a new valve inside a failed bioprosthetic valve to replace the faulty one without needing repeat open heart surgery.

    HealthTech guidance
    Published
    22 September 2021
    View recommendations

    Sections for HTG592

  37. Hybrid closed loop systems for managing blood glucose levels in type 1 diabetes (TA943)

    Evidence-based recommendations on hybrid closed loop systems for managing blood glucose levels in type 1 diabetes.

    Technology appraisal guidance
    Published
    19 December 2023
    View recommendations

    Sections for TA943

  38. Endovascular stent-grafting of popliteal aneurysms (HTG259)

    Evidence-based recommendations on endovascular stent-grafting of popliteal aneurysms. This involves inserting a ‘stent-graft’ device through the femoral artery (in the groin) lining the inside of the aneurysm.

    HealthTech guidance
    Published
    27 April 2011
    View recommendations

    Sections for HTG259

  39. Exagamglogene autotemcel for treating severe sickle cell disease in people 12 years and over (TA1044)

    Evidence-based recommendations on exagamglogene autotemcel (Casgevy) for treating severe sickle cell disease in people 12 years and over.

    Technology appraisal guidance
    Published
    26 February 2025
    View recommendations

    Sections for TA1044

  40. Frequency of application of topical corticosteroids for atopic eczema (TA81)

    Evidence-based recommendations on using topical corticosteroids for people with atopic eczema.

    Technology appraisal guidance
    Published
    25 August 2004
    View recommendations

    Sections for TA81

  41. Robot-assisted kidney transplant (HTG468)

    Evidence-based recommendations on robot-assisted kidney transplant in adults. This involves the surgeon using a robot to help with a kidney transplant.

    HealthTech guidance
    Published
    25 April 2018
    View recommendations

    Sections for HTG468

  42. Bladder cancer (QS106)

    This quality standard covers diagnosing and managing bladder cancer in adults (aged 18 and over) referred from primary care. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    17 December 2015
    View quality statements

    Sections for QS106

  43. Head injury (QS74)

    This quality standard covers assessment, early management and rehabilitation following head injury in adults, young people and children. It describes high-quality care in priority areas for improvement.

    Quality standard
    Last updated
    15 October 2025
    View quality statements

    Sections for QS74

  44. Lenalidomide with rituximab for previously treated follicular lymphoma (TA627)

    Evidence-based recommendations on lenalidomide (Revlimid) with rituximab for previously treated follicular lymphoma (grade 1 to 3A) in adults.

    Technology appraisal guidance
    Published
    7 April 2020
    View recommendations

    Sections for TA627

  45. Percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events (HTG325)

    Evidence-based recommendations on percutaneous closure of the patent foramen ovale for the prevention of cerebral embolic stroke. This involves placing a small device into the heart to close the hole.

    HealthTech guidance
    Published
    18 December 2013
    View recommendations

    Sections for HTG325

  46. Interventional procedures programme manual (PMG28)

    This guide describes the methods that NICE follows when evaluating interventional procedures. Processes for interventional procedures are in section 1 of the NICE HealthTech programme manual

  47. Laparoscopic gastric plication for the treatment of severe obesity (HTG293)

    Evidence-based recommendations on laparoscopic gastric plication for the treatment of morbid obesity. This involves folding the stomach in on itself and stitching it together to reduce its volume.

    HealthTech guidance
    Published
    27 November 2012
    View recommendations

    Sections for HTG293

  48. Everolimus for preventing organ rejection in liver transplantation (TA348)

    Evidence-based recommendations on everolimus (Certican) for preventing organ rejection in adults having a liver transplant.

    Technology appraisal guidance
    Published
    22 July 2015
    View recommendations

    Sections for TA348

  49. Carfilzomib with dexamethasone and lenalidomide for previously treated multiple myeloma (TA695)

    Evidence-based recommendations on carfilzomib (Kyprolis) with dexamethasone and lenalidomide (Revlimid) for previously treated multiple myeloma in adults.

    Technology appraisal guidance
    Published
    28 April 2021
    View recommendations

    Sections for TA695

  50. Prosthetic intervertebral disc replacement in the lumbar spine (HTG197)

    Evidence-based recommendations on prosthetic intervertebral disc replacement in the lumbar spine. This involves removing the damaged disc and inserting an artificial disc in its place.

    HealthTech guidance
    Published
    22 July 2009
    View recommendations

    Sections for HTG197