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This guidance has been replaced by NICE technology appraisal guidance 71.
The clinical effectiveness and cost effectiveness of infliximab for Crohn's disease (TA40)
This guidance has been updated and replaced by NICE technology appraisal guidance 187.
Guidance on the use of metal on metal hip resurfacing arthroplasty (TA44)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Daclizumab for treating relapsing–remitting multiple sclerosis (TA441)
This guidance has been withdrawn because Biogen is withdrawing its marketing authorisations for daclizumab. See the European Medicines Agency’s advice on daclizumab.
Brentuximab vedotin for treating CD30-positive Hodgkin lymphoma (TA446)
This guidance has been updated and replaced by NICE technology appraisal guidance 524.
Pembrolizumab for untreated PD-L1-positive metastatic non-small-cell lung cancer (TA447)
This guidance has been updated and replaced by NICE technology appraisal guidance 531.
This guidance has been updated and replaced by NICE technology appraisal guidance 91.
This advice has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Eluxadoline for treating irritable bowel syndrome with diarrhoea (TA471)
We have withdrawn this guidance. Allergan has stopped marketing eluxadoline (Truberzi) for commercial reasons and its marketing authorisation has been withdrawn.
Obinutuzumab with bendamustine for treating follicular lymphoma refractory to rituximab (TA472)
This guidance has been updated and replaced by NICE technology appraisal guidance 629.
This guidance has been updated and replaced by NICE guideline NG107
Nivolumab for previously treated squamous non-small-cell lung cancer (TA483)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 655.
Nivolumab for previously treated non-squamous non-small-cell lung cancer (TA484)
This guidance has been updated and replaced by NICE technology appraisal guidance 713.
Venetoclax for treating chronic lymphocytic leukaemia (TA487)
This guidance has been updated and replaced by NICE technology appraisal guidance 796.
This guidance has been updated and replaced by NICE guideline CG82.
Mepolizumab for treating severe refractory eosinophilic asthma (TA431)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 671.
This guidance has been updated and replaced by NICE guideline PH10.
This guidance has been updated and replaced by NICE technology appraisal guidance 402.
The clinical effectiveness and cost effectiveness of sibutramine for obesity (TA31)
This guidance has been replaced by NICE guideline CG43.
Bivalirudin for the treatment of ST-segment-elevation myocardial infarction (TA230)
This guideline has been updated and replaced by NICE guideline NG185.
Retigabine for the adjunctive treatment of partial onset seizures in epilepsy (TA232)
The guidance has been withdrawn because GlaxoSmithKline has discontinued retigabine (Trobalt) due to limited usage.
Golimumab for the treatment of ankylosing spondylitis (TA233)
This guidance has been updated and replaced by NICE technology appraisal guidance 383.
This guidance has been updated and replaced by NICE technology appraisal guidance 280.
Ranibizumab for the treatment of diabetic macular oedema (TA237)
This guidance has been updated and replaced by NICE technology appraisal guidance 274.
This guidance has been replaced by NICE guideline CG74.
This guidance has been replaced by NICE technology appraisal guidance 75.
Infliximab for subacute manifestations of ulcerative colitis (TA140)
This guidance has been updated and replaced by NICE technology appraisal guidance 329.
This appraisal has been updated and replaced by NICE technology appraisal guidance 195.
Epoetin alfa, epoetin beta and darbepoetin alfa for cancer treatment-induced anaemia (TA142)
This guidance has been replaced by NICE technology appraisal guidance 323.
Adalimumab, etanercept and infliximab for ankylosing spondylitis (TA143)
This guidance has been updated and replaced by NICE technology appraisal guidance 383.
Rimonabant for the treatment of overweight and obese adults (TA144)
This appraisal has been withdrawn. This is because the marketing authorisation for rimonabant was withdrawn on 16 January 2009.
Bevacizumab for the first-line treatment of metastatic breast cancer (TA147)
This appraisal has been updated and replaced by NICE technology appraisal 214.
This guidance has been replaced by NICE technology appraisal guidance 98 [Replaced by NICE guideline NG87].
Adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis (TA130)
This guidance has been updated and replaced by NICE technology appraisal guidance 375.
This guidance has been updated and replaced by the NICE guideline on asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN).
This guidance has been updated and replaced by NICE technology appraisal guidance 385.
This guidance has been replaced by NICE technology appraisal guidance 278.
This guidance has been withdrawn because Novartis has discontinued ofatumumab (Arzerra). Ofatumumab will continue to be available for people who need it. Contact Clinigen at managedacess@clinigengroup.com or 01932 842100 for details.
Liraglutide for the treatment of type 2 diabetes mellitus (TA203)
This guidance has been updated and replaced by NICE guideline NG28.
Eltrombopag for the treatment of chronic immune (idiopathic) thrombocytopenic purpura (TA205)
This guidance has been updated and replaced by NICE technology appraisal guidance 293.
This guidance has been replaced by NICE technology appraisal guidance 63 [Replaced by NICE guideline CG66].
Imatinib for the adjuvant treatment of gastrointestinal stromal tumours (TA196)
This guidance has been replaced by NICE technology appraisal guidance 326.
Tocilizumab for the treatment of rheumatoid arthritis (TA198)
This guidance has been updated and replaced by NICE technology appraisal guidance 247.
Guidance on the Selection of Prostheses for Primary Total Hip Replacement (TA2)
This guidance has been updated and replaced by NICE technology appraisal guidance 304.
Omalizumab for the treatment of severe persistent allergic asthma in children aged 6–11 (TA201)
This guidance has been updated and replaced by NICE technology appraisal guidance 278.
Autologous cartilage transplantation for full thickness cartilage defects in knee joints (TA16)
This guidance has been replaced by NICE technology appraisal guidance 89 [Replaced by NICE technology appraisal guidance 477].
Erlotinib for the treatment of non-small-cell lung cancer (TA162)
This guidance has been updated and replaced by NICE technology appraisal guidance 374.
Febuxostat for the management of hyperuricaemia in people with gout (TA164)
This guidance has been updated and replaced by NICE guideline NG219.
Cochlear implants for children and adults with severe to profound deafness (TA166)
This guidance has been updated and replaced by NICE technology appraisal guidance 566.