Search results

This guideline covers care during labour and birth for women who need extra support because they have a medical condition or complications in their current or previous pregnancy. The guideline also covers women who have had no antenatal care. It aims to improve experiences and outcomes for women and their babies.

Result type

NICE guideline

Last updated

25 April 2019

Evidence-based recommendations on tebentafusp (Kimmtrak) for treating uveal melanoma in adults.

Result type

Technology appraisal guidance

Published

9 January 2025

Early value assessment (EVA) guidance on digital technologies to support self-management of COPD.

Result type

HealthTech guidance

Last updated

3 February 2026

Evidence-based recommendations on brentuximab vedotin (Adcetris) for treating CD30-positive cutaneous T-cell lymphoma in adults.

Result type

Technology appraisal guidance

Published

24 April 2019

Evidence-based recommendations on dapagliflozin (Forxiga) given with other drugs for treating type 2 diabetes in adults.

Result type

Technology appraisal guidance

Last updated

23 November 2016

Evidence-based recommendations on transcatheter aortic valve implantation (TAVI) for aortic stenosis. This involves inserting a new valve through a catheter, usually by way of a large blood vessel at the top of the leg, into the heart and inside the existing faulty valve.

Result type

HealthTech guidance

Published

26 July 2017

Evidence-based recommendations on nivolumab (Opdivo) as a possible treatment for completely resected oesophageal or gastro-oesophageal junction cancer in adults.

Result type

Technology appraisal guidance

Published

17 November 2021

Evidence-based recommendations on pemetrexed for treating non-small-cell lung cancer in adults.

Result type

Technology appraisal guidance

Published

22 August 2007

This resource is intended to demonstrate how our guidance can be used in the Care Quality Commission (CQC) assessment process.

Evidence-based recommendations on radiofrequency ablation for the treatment of colorectal liver metastases. This involves using heat to destroy cancer cells in the liver.

Result type

HealthTech guidance

Published

16 December 2009

Evidence-based recommendations on talazoparib (Talzenna) for HER2-negative, locally advanced or metastatic breast cancer with germline BRCA1 or BRCA2 mutations in adults.

Result type

Technology appraisal guidance

Published

21 February 2024

Evidence-based recommendations on laparoscopic liver resection. This involves making small incisions (keyhole surgery) to remove the parts of the liver that are benign or cancerous.

Result type

HealthTech guidance

Published

27 July 2005

This quality standard covers the prevention or delay of harmful use of drugs by children, young people and adults most likely to start using drugs, or already experimenting or using drugs occasionally. This includes illegal psychoactive substances, solvents, volatile substances, image- and performance-enhancing drugs, prescription-only medicines and over-the-counter medicines. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

29 March 2018

Evidence-based recommendations on arthroscopic trochleoplasty for patellar instability. This involves reshaping the bony anatomy of the trochlea by deepening the groove or elevating the lateral wall.

Result type

HealthTech guidance

Published

23 January 2014

Evidence-based recommendations on interspinous distraction procedures for lumbar spinal stenosis causing neurogenic claudication. This involves implanting a device into the space between two back bones to relieve pressure on the nerves and, therefore, pain in the legs.

Result type

HealthTech guidance

Published

24 November 2010

Evidence-based recommendations on MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy in adults and children. This involves inserting a laser into the area of the brain causing seizures.

Result type

HealthTech guidance

Published

4 March 2020

Evidence-based recommendations on EarlyCDT Lung for assessing the risk of lung cancer in solid lung nodules.

Result type

HealthTech guidance

Published

23 February 2022

Evidence-based recommendations on trastuzumab deruxtecan (Enhertu) for treating HER2-positive unresectable or metastatic breast cancer in adults after 2 or more anti-HER2 therapies.

Result type

Technology appraisal guidance

Published

26 May 2021

This quality standard covers care for women of any age (including girls and young women under 18) who request an abortion. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

26 January 2021

Summary of the evidence on botulinum toxin type A injection for treating chronic anal fissure to inform local NHS planning and decision-making

Result type

Evidence summary

Published

25 June 2013

Evidence-based recommendations on sofosbuvir (Sovaldi) for treating some types of chronic hepatitis C (HCV)

Result type

Technology appraisal guidance

Published

25 February 2015

Evidence-based recommendations on endoscopic radical inguinal lymphadenectomy. This involves using an endoscopic device and small incisions to reduce discomfort, scarring and complications associated with inguinal lymph node removal.

Result type

HealthTech guidance

Published

22 June 2011

Evidence-based recommendations on free-functioning gracilis transfer to restore upper limb function in brachial plexus injury in adults. This involves taking a piece of hamstring muscle and its nerve and blood supply from the inner thigh, transferring it to the arm and joining it to the damaged nerve.

Result type

HealthTech guidance

Published

3 March 2021

Evidence-based recommendations on placement of pectus bar for pectus excavatum (Nuss procedure). This involves placing one or two steel (pectus) bars under the breastbone with the aim of raising it and correcting the abnormal shape.

Result type

HealthTech guidance

Published

26 August 2009

Evidence-based recommendations on transcutaneous stimulation of the cervical branch of the vagus nerve to treat cluster headache and migraine in adults. This involves using a small handheld device to stimulate a nerve in the neck.

Result type

HealthTech guidance

Published

23 March 2016

Evidence-based recommendations on difelikefalin (Kapruvia) for pruritus in adults with chronic kidney disease having haemodialysis.

Result type

Technology appraisal guidance

Published

17 May 2023

Evidence-based recommendations on sacituzumab govetican (Trodelvy) for treating unresectable, triple-negative locally advanced or metastatic breast cancer in adults after 2 or more systemic therapies, at least 1 of which was for advanced disease.

Result type

Technology appraisal guidance

Published

17 August 2022

Evidence-based recommendations on durvalumab (Imfinzi) with tremelimumab (Imjudo) for untreated advanced or unresectable hepatocellular carcinoma in adults.

Result type

Technology appraisal guidance

Published

19 August 2025

Evidence-based recommendations on pitolisant hydrochloride for treating excessive daytime sleepiness caused by obstructive sleep apnoea in adults.

Result type

Technology appraisal guidance

Published

9 March 2022

Evidence-based recommendations on thoracoscopic repair of congenital diaphragmatic hernia in neonates. This involves inserting surgical instruments through small cuts in the chest, and then moving the abdominal organs out of the chest and repairing the diaphragm.

Result type

HealthTech guidance

Published

25 January 2011

Evidence-based recommendations on laparoscopic ventral mesh rectopexy for internal rectal prolapse in adults. This involves using a piece of sterile material (mesh) to attach the rectum to the lower back bone using keyhole surgery.

Result type

HealthTech guidance

Published

20 June 2018

Evidence-based recommendations on valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) for aortic bioprosthetic valve dysfunction in adults. This involves placing a new bioprosthetic valve inside a failing bioprosthetic valve.

Result type

HealthTech guidance

Published

26 June 2019

Evidence-based recommendations on cladribine (Mavenclad) for relapsing–remitting multiple sclerosis in adults.

Result type

Technology appraisal guidance

Last updated

21 May 2024

This quality standard covers the assessment and early management of fever with no obvious cause in babies and children (from birth to 5 years). It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Last updated

27 July 2022

Evidence-based recommendations on temozolomide (Temodal) for malignant glioma in children over 3 years, young people and adults.

Result type

Technology appraisal guidance

Last updated

3 March 2016

Evidence-based recommendations on lenvatinib (Kisplyx) with everolimus for previously treated advanced renal cell carcinoma in adults.

Result type

Technology appraisal guidance

Published

24 January 2018

This guideline covers assessing risk of falling and interventions to prevent falls in all people aged 65 and over, and people aged 50 to 64 who are at higher risk of falls. It aims to reduce the risk and incidence of falls, and the associated distress, pain, injury, loss of confidence, loss of independence and mortality.

Result type

NICE guideline

Published

29 April 2025

Evidence-based recommendations on individually magnetic resonance imaging-designed unicompartmental interpositional implant insertion for osteoarthritis of the knee. This involves inserting an individually designed implant at the knee between the thigh and shin bones to realign the knee and prevent bone-on-bone rubbing.

Result type

HealthTech guidance

Published

23 September 2009

Evidence-based recommendations on endoscopic full thickness removal of gastrointestinal stromal tumours of the stomach. This involves removing a tumour using an endoscope and forceps. The aim is to remove the tumour without the need for open surgery.

Result type

HealthTech guidance

Published

2 March 2022

Evidence-based recommendations on endoluminal gastroplication for gastro-oesophageal reflux disease. This involves an endoscopic fastening device being inserted through the mouth and into the stomach, along with an endoscope for constant visualisation. The device is used to attach the fundus to the anterior and left lateral wall of the distal oesophagus slightly above the oesophagogastric junction.

Result type

HealthTech guidance

Published

1 March 2023

Evidence-based recommendations on dabrafenib (Finlee) with trametinib (Spexotras) for treating BRAF V600E mutation-positive glioma in children and young people aged 1 year and over.

Result type

Technology appraisal guidance

Published

29 May 2024

Evidence-based recommendations on teduglutide (Resvestive) for treating short bowel syndrome in people 1 year and above.

Result type

Technology appraisal guidance

Published

30 June 2022

Evidence-based recommendations on caplacizumab (Cablivi) with plasma exchange and immunosuppression for treating acute acquired thrombotic thrombocytopenic purpura in adults, and in young people aged 12 years and over who weigh at least 40 kg.

Result type

Technology appraisal guidance

Published

16 December 2020

Evidence-based recommendations on percutaneous insertion of a cerebral protection device to prevent cerebral embolism during TAVI in adults. This involves placing a device inside an artery near the heart.

Result type

HealthTech guidance

Published

12 June 2019

Evidence-based recommendations on rituximab (MabThera) with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitis in adults.

Result type

Technology appraisal guidance

Published

26 March 2014

This guideline covers diagnosing and managing irritable bowel syndrome (IBS) in people aged 18 and over. It details how to accurately diagnose IBS, and aims to improve the quality of life for adults with IBS by promoting effective management using dietary and lifestyle advice, pharmacological therapy and referral for psychological interventions.

Result type

Clinical guideline

Last updated

4 April 2017

Evidence-based recommendations on Endo-SPONGE for treating low rectal anastomotic leak.

Result type

HealthTech guidance

Published

16 December 2021

for treating and preventing migraine. Data should be collected for all patients not entered into controlled trials. Studies should...

Result type

Research recommendation

Published

9 June 2015

Evidence-based recommendations on ENDURALIFE-powered CRT-D devices for treating heart failure.

Result type

HealthTech guidance

Last updated

21 July 2021

Evidence-based recommendations on thoracoscopic epicardial radiofrequency ablation for atrial fibrillation. This involves using heat to destroy the selected areas of the heart to prevent the occurrence or conduction of abnormal electrical activity.

Result type

HealthTech guidance

Published

28 January 2009