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Evidence-based recommendations on palbociclib (Ibrance) as initial endocrine-based therapy for hormone-receptor positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic (secondary) breast cancer in adults.
GaitSmart rehabilitation exercise programme for gait and mobility issues (HTG716)
Evidence-based recommendations on GaitSmart rehabilitation exercise programme for gait and mobility issues in adults.
Evidence-based recommendations on point-of-care creatinine devices to assess kidney function before CT imaging with intravenous contrast. The tests are ABL800 FLEX, i-STAT Alinity and StatSensor, ABL90 FLEX PLUS, Dri chem NX500, epoc Blood Analysis System, and Piccolo Xpress.
Urinary incontinence and pelvic organ prolapse in women: management (NG123)
This guideline covers assessing and managing urinary incontinence and pelvic organ prolapse in women aged 18 and over. It also covers complications associated with mesh surgery for these conditions.
pathway:- In the UK, what is the optimal care pathway for young people and adults with coexisting severe mental illness and substance...
interpersonal interactions and relationships, major life areas, community, and social and civil life. There is evidence suggesting that...
Refractory [Irritable bowel syndrome] (IBS):- What factors contribute to refractory IBS?
profile, psychological symptoms, childhood adversity, psychiatric history, social supports, quality of life and other relevant potential...
Onasemnogene abeparvovec for treating presymptomatic spinal muscular atrophy (HST24)
Evidence-based recommendations on onasemnogene abeparvovec (Zolgensma) for treating presymptomatic spinal muscular atrophy in babies aged 12 months and under.
facilitators:- What are the barriers and facilitators for young people and adults with coexisting severe mental illness and substance...
structure and composition, to providing home-based intermediate care for adults? Any explanatory notes(if applicable) Why this is...
How cost effective are fluoride varnish programmes and tooth-brushing schemes?
outcomes should include the use of non-dental health and social care services by children and adults, such as numbers...
outcomes should include the use of non-dental health and social care services by children and adults, such as numbers...
include symptoms, relapse rates, quality of life, treatment acceptability, social functioning and the cost effectiveness of the...
Romiplostim for the treatment of chronic immune thrombocytopenia (TA221)
Evidence-based recommendations on romiplostim (Nplate) for treating chronic immune thrombocytopenia in adults.
NICE technology appraisal and highly specialised technologies guidance: the manual (PMG36)
This guide describes the methods and processes, including expected timescales, that NICE follows when carrying out health technology evaluations. The methods and processes are designed to produce robust guidance for the NHS in an open, transparent and timely way, with appropriate contribution from stakeholders. Organisations invited to contribute to health technology evaluation development should read this manual in conjunction with the NICE health technology evaluation topic selection: the manual. All documents are available on the NICE website