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NICE has developed a medtech innovation briefing (MIB) on the Aquilion PRIME CT scanner for imaging coronary artery disease in adults in whom imaging is difficult .

Result type

Medtech innovation briefing

Last updated

6 July 2017

Evidence-based recommendations on obecabtagene autoleucel (obe-cel; Aucatzyl) for treating relapsed or refractory B-cell precursor acute lymphoblastic leukaemia in adults.

Result type

Technology appraisal guidance

Published

11 December 2025

indefinitely compared with zoledronic acid given for a fixed duration in patients with myeloma? Any explanatory notes(if applicable) Why...

Result type

Research recommendation

Published

5 April 2016

This interim process and methods statement sets out the general principles guiding NICE's approach to including NICE technology appraisal recommendations in guideline topic areas. It also describes what the key changes are to existing methods and processes

NICE has developed a medtech innovation briefing (MIB) on OrganOx metra for liver transplant .

Result type

Medtech innovation briefing

Published

14 September 2021

Evidence-based recommendations on endoscopic dacryocystorhinostomy for treating lacrimal sac or nasolacrimal duct obstruction. This involves making a connection that bypasses the blocked area so that the tears can drain straight into the nose.

Result type

Interventional procedures guidance

Published

23 February 2005

Evidence-based recommendations on shoulder resurfacing arthroplasty. This involves reshaping the upper arm bone and placing an artificial shoulder joint onto it.

Result type

Interventional procedures guidance

Published

28 July 2010

Evidence-based recommendations on delgocitinib (Anzupgo) for treating moderate to severe chronic hand eczema in adults when topical corticosteroids have not worked or are not suitable.

Result type

Technology appraisal guidance

Published

5 November 2025

NICE makes 4 types of recommendation that allow us to produce clear, directive, actionable guidance that is easy to understand and put into practice.

Evidence-based recommendations on laparoscopic gastrectomy for cancer. This involves partial or total removal of the stomach to take out the tumour and affected lymph nodes through small cuts in the abdomen (keyhole surgery).

Result type

Interventional procedures guidance

Published

23 July 2008

Evidence-based recommendations on Plus Sutures for preventing surgical site infection.

Result type

HealthTech guidance

Published

28 June 2021

Evidence-based recommendations on laparoscopic cerclage for cervical incompetence to prevent late miscarriage or preterm birth. This involves placing a stitch around the upper part of the cervix to keep it closed.

Result type

Interventional procedures guidance

Published

30 January 2019

Evidence-based recommendations on laparoscopic cryotherapy for renal cancer. This involves inserting a surgical instrument (cryoprobe) to apply freezing temperatures to the tumour and destroy the cancer cells.

Result type

Interventional procedures guidance

Published

24 August 2011

Evidence-based recommendations on laparoscopic partial nephrectomy. This involves making small ‘keyhole’ openings, either in the back or in the abdomen, to remove the section of kidney that contains the tumour.

Result type

Interventional procedures guidance

Published

25 January 2006

This guideline covers recognising, diagnosing and managing vitamin B12 deficiency in people aged 16 and over, including deficiency caused by autoimmune gastritis. It also covers monitoring for gastric cancer in people with autoimmune gastritis.

Result type

NICE guideline

Published

6 March 2024

Evidence-based recommendations on the implantation of multifocal (non-accommodative) intraocular lenses during cataract surgery. This involves replacing the clouded lens with an artificial one with areas of different focusing power to allow near and distant objects to be seen.

Result type

Interventional procedures guidance

Published

25 June 2008

Evidence-based recommendations on fallopian tube recanalisation by guidewire. This involves injecting dye through a narrow tube inserted into the fallopian tube and if this does not unblock it, using a guidewire.

Result type

Interventional procedures guidance

Published

28 July 2004

Evidence-based recommendations on testing strategies for Lynch syndrome for people with endometrial cancer.

Result type

HealthTech guidance

Published

28 October 2020

Evidence-based recommendations on vagus nerve stimulation for refractory epilepsy in children. This involves placing a device under the skin to send a burst of nerve messages through the nerve.

Result type

Interventional procedures guidance

Published

24 March 2004

Evidence-based recommendations on therapeutic sialendoscopy. This involves using a flexible tube to enter the salivary gland, and visualise and remove the stone.

Result type

Interventional procedures guidance

Published

23 May 2007

This quality standard covers the care of adults (aged 18 and over) with suspected or confirmed acute heart failure. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

3 December 2015

Evidence-based recommendations on cyanoacrylate instillation for occlusion of parotid sinuses. This involves injecting a solution of lipiodiol and cyanoacrylate via the sinus into the parotid gland, sealing the sinus.

Result type

Interventional procedures guidance

Published

25 February 2004

Evidence-based recommendations on percutaneous image-guided cryoablation of peripheral neuroma for chronic pain. This involves using a needle-like probe to freeze and destroy small parts of nerves in neuromas to stop the pain signals.

Result type

Interventional procedures guidance

Published

4 January 2023

Evidence-based recommendations on sacral nerve stimulation for urge incontinence and urgency-frequency. This involves placing electrodes and connecting them to an implantable pulse generator.

Result type

Interventional procedures guidance

Published

23 June 2004

This guideline covers support to stop smoking for everyone aged 12 and over, and help to reduce people's harm from smoking if they are not ready to stop in one go. It also covers ways to prevent children, young people and young adults aged 24 and under from taking up smoking.

Result type

NICE guideline

Last updated

4 February 2025

Evidence-based recommendations on capecitabine for treating advanced gastric cancer in adults.

Result type

Technology appraisal guidance

Published

28 July 2010

Evidence-based recommendations on leadless cardiac pacemaker implantation for bradyarrhythmias in adults. This involves inserting a device into the heart that helps it beat at a normal rate.

Result type

Interventional procedures guidance

Published

29 August 2018

Evidence-based recommendations on sacropolpopexy using mesh to repair vaginal vault prolapse in women. This involves attaching mesh, usually from the top of the vagina to the base of the spine, to support the pelvic organs.

Result type

Interventional procedures guidance

Published

28 June 2017

Evidence-based recommendations on mini-incision surgery for total knee replacement. This involves using specially designed instruments to replace the knee using a smaller incision.

Result type

Interventional procedures guidance

Published

26 May 2010

Evidence-based recommendations on implantation of accommodating intraocular lenses for cataract. This involves removing the clouded natural lens of the eye and replacing it with an accommodating lens to allow focusing on near and distant objects.

Result type

Interventional procedures guidance

Published

28 February 2007

Evidence-based recommendations on endopyelotomy for pelviureteric junction obstruction. This involves widening the renal pelvis by inserting small instruments either up through the urinary tract or down through the skin and into the kidney.

Result type

Interventional procedures guidance

Published

16 December 2009

Evidence-based recommendations on computed tomography-guided thermocoagulation of osteoid osteoma. This involves using high-frequency energy to heat the growth and destroy it.

Result type

Interventional procedures guidance

Published

24 March 2004

NICE has developed a medtech innovation briefing (MIB) on lung texture analysis for measuring interstitial lung diseases .

Result type

Medtech innovation briefing

Published

10 August 2021

This guideline covers diagnosing and managing epilepsy in children, young people and adults in primary and secondary care, and referral to tertiary services. It aims to improve diagnosis and treatment for different seizure types and epilepsy syndromes, and reduce the risks for people with epilepsy.

Result type

NICE guideline

Last updated

30 January 2025

This guideline covers diagnosing and managing spondyloarthritis that is suspected or confirmed in adults who are 16 years or older. It aims to raise awareness of the features of spondyloarthritis and provide clear advice on what action to take when people with signs and symptoms first present in healthcare settings. It also provides advice on the range of treatments available.

Result type

NICE guideline

Last updated

2 June 2017

Evidence-based recommendations on injectable bulking agents for faecal incontinence. This involves injecting a material into the muscles around the anus to bulk the sides of the sphincter.

Result type

Interventional procedures guidance

Published

28 February 2007

Evidence-based recommendations on endovascular stent–graft placement in thoracic aortic aneurysms and dissections. This involves placing a stent covered in graft material inside the aorta under X-ray guidance.

Result type

Interventional procedures guidance

Published

22 June 2005

Evidence-based recommendations on extracorporeal shockwave therapy for refractory tennis elbow. This involves using a machine to deliver sound waves to the painful area to stimulate healing.

Result type

Interventional procedures guidance

Published

26 August 2009

Evidence-based recommendations on endovenous laser treatment of the long saphenous vein. This involves using laser and heat to seal up the vein.

Result type

Interventional procedures guidance

Published

24 March 2004

Early value assessment (EVA) guidance on artificial intelligence (AI) technologies to aid opportunistic detection of vertebral fragility fractures.

Result type

HealthTech guidance

Published

14 October 2025

Evidence-based recommendations on laser sheath removal of pacing leads. This involves using a special tube (sheath) placed over the leads in the veins to destroy the scar tissue around the leads and pull the pacemaker lead away from the heart.

Result type

Interventional procedures guidance

Published

23 June 2004

NICE has developed a medtech innovation briefing (MIB) on PleuraFlow Active Clearance Technology for maintaining chest tube patency .

Result type

Medtech innovation briefing

Published

16 October 2017

The adoption and implementation team provides support to the system to enable the effective use of NICE guidance.

This guideline covers specific aspects of respiratory support (for example, oxygen supplementation, assisted ventilation, treatment of some respiratory disorders, and aspects of monitoring) for preterm babies in hospital.

Result type

NICE guideline

Published

3 April 2019

Evidence-based recommendations on radiofrequency ablation as an adjunct to balloon kyphoplasty or percutaneous vertebroplasty for palliation of painful spinal metastases. This involves inserting a needle-like probe containing an electrode into the spinal metastases. This produces an electrical current that aims to relieve pain and other symptoms.

Result type

Interventional procedures guidance

Published

5 April 2023

Evidence-based recommendations on endoscopic duodenal mucosal resurfacing for insulin resistance in type 2 diabetes. This involves using heat to destroy the lining of the duodenum to encourage a new lining to grow.

Result type

Interventional procedures guidance

Published

16 May 2024

Evidence-based recommendations on radiofrequency valvotomy for pulmonary atresia. This involves making a hole in the blocked valve, and inserting and inflating a small balloon to widen it.

Result type

Interventional procedures guidance

Published

27 October 2004

NICE has developed a medtech innovation briefing (MIB) on Mobi-C for cervical disc replacement

Result type

Medtech innovation briefing

Published

28 June 2016

Evidence-based recommendations on repetitive transcranial magnetic stimulation for depression. This involves placing an electromagnetic coil against the scalp, which creates electric currents in certain parts of the brain.

Result type

Interventional procedures guidance

Published

16 December 2015

Evidence-based recommendations on suction diathermy adenoidectomy. This involves using heat and suction to remove the adenoids.

Result type

Interventional procedures guidance

Published

16 December 2009