Search results

Evidence-based recommendations on atidarsagene autotemcel (Libmeldy) for treating metachromatic leukodystrophy in children.

Result type

Highly specialised technologies guidance

Published

28 March 2022

Evidence-based recommendations on bioresorbable stent implantation to treat coronary artery disease in adults. This involves implanting a stent (small tube) into a narrowed artery to widen it.

Result type

Interventional procedures guidance

Published

3 August 2022

Evidence-based recommendations on middle meningeal artery embolisation for chronic subdural haematomas. This involves injecting particles into the middle meningeal artery to block it.

Result type

Interventional procedures guidance

Published

14 December 2023

This guideline covers diagnosing and managing spondyloarthritis that is suspected or confirmed in adults who are 16 years or older. It aims to raise awareness of the features of spondyloarthritis and provide clear advice on what action to take when people with signs and symptoms first present in healthcare settings. It also provides advice on the range of treatments available.

Result type

NICE guideline

Last updated

2 June 2017

NICE has developed a medtech innovation briefing (MIB) on PromarkerD for predicting the risk of diabetic kidney disease in people with type 2 diabetes .

Result type

Medtech innovation briefing

Published

13 December 2022

Evidence-based recommendations on VA ECMO for extracorporeal cardiopulmonary resuscitation (ECPR) in adults with refractory cardiac arrest. This involves using an artificial lung to oxygenate the blood outside the body.

Result type

Interventional procedures guidance

Published

22 October 2025

indefinitely compared with zoledronic acid given for a fixed duration in patients with myeloma? Any explanatory notes(if applicable) Why...

Result type

Research recommendation

Published

5 April 2016

Evidence-based recommendations on phototherapeutic laser keratectomy for corneal surface irregularities. This involves using a laser to remove layers of the cornea in order to produce a smooth, even surface with the aim of improving vision.

Result type

Interventional procedures guidance

Published

22 September 2010

Evidence-based recommendations on extracorporeal shockwave therapy for refractory plantar fasciitis. This involves using a machine to deliver sound waves to the painful area, with the aim to stimulate healing of the fascia.

Result type

Interventional procedures guidance

Published

26 August 2009

Evidence-based recommendations on corneal inlay implantation for correction of Presbyopia. This involves placing a disc inside a flap or pocket made in the cornea to improve near vision.

Result type

Interventional procedures guidance

Published

26 April 2013

Evidence-based recommendations on percutaneous endoscopic laser thoracic discectomy. This involves using a laser to heat and destroy some of the inside of the disc and shrink the part that is sticking out.

Result type

Interventional procedures guidance

Published

27 May 2004

Evidence-based recommendations on interstitial laser therapy for fibroadenomas of the breast. This involves using high-energy light from a laser to destroy the lump.

Result type

Interventional procedures guidance

Published

22 June 2005

Evidence-based recommendations on laparoscopic nephrectomy (including nephroureterectomy). This involves making small incisions (keyhole surgery) to remove the damaged kidney, or kidney, ureter and surrounding tissue.

Result type

Interventional procedures guidance

Published

24 August 2005

Evidence-based recommendations on transperineal template biopsy of the prostate. This involves inserting many fine needles though the skin between the scrotum and the anus in order to obtain tissue samples from the prostate for testing.

Result type

Interventional procedures guidance

Published

27 October 2010

Evidence-based recommendations on permanent His-bundle pacemaker implantation for treating heart failure. This involves attaching a wire connected to a pacemaker to the heart’s electrical conduction pathway (through a vein).

Result type

Interventional procedures guidance

Published

5 May 2021

Evidence-based recommendations on transcutaneous electrical neuromuscular stimulation for urinary incontinence in adults. This involves stimulating nerves and muscles in the pelvic floor to strengthen the muscles and reduce urine leaks.

Result type

Interventional procedures guidance

Published

24 August 2022

Evidence-based recommendations on phrenic nerve pacing for ventilator-dependent high cervical spinal cord injury. This involves stimulating the phrenic nerve to make the diaphragm contract, helping people to breathe without a ventilator.

Result type

Interventional procedures guidance

Published

21 August 2024

This guideline covers support to stop smoking for everyone aged 12 and over, and help to reduce people's harm from smoking if they are not ready to stop in one go. It also covers ways to prevent children, young people and young adults aged 24 and under from taking up smoking.

Result type

NICE guideline

Last updated

4 February 2025

This guideline covers diagnosing and managing epilepsy in children, young people and adults in primary and secondary care, and referral to tertiary services. It aims to improve diagnosis and treatment for different seizure types and epilepsy syndromes, and reduce the risks for people with epilepsy.

Result type

NICE guideline

Last updated

30 January 2025

Evidence-based recommendations on CYP2C19 genotype testing to guide clopidogrel use after ischaemic stroke or transient ischaemic attack.

Result type

HealthTech guidance

Published

31 July 2024

NICE has developed a medtech innovation briefing (MIB) on EpiFix for chronic wounds .

Result type

Medtech innovation briefing

Published

30 January 2018

Evidence-based recommendations on endoscopic injection of bulking agents for gastro-oesophageal reflux disease. This involves injecting a filler into the junction using a catheter to make the entry to the stomach narrower, so that the contents of the stomach cannot pass back.

Result type

Interventional procedures guidance

Published

28 April 2004

Evidence-based recommendations on artificial intelligence (AI)-derived computer-aided detection (CAD) software for detecting and measuring lung nodules in CT scan images.

Result type

HealthTech guidance

Published

5 July 2023

This quality standard covers the care of adults (aged 18 and over) with suspected or confirmed acute heart failure. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

3 December 2015

Evidence-based recommendations on intramural urethral bulking procedures for stress urinary incontinence in women. Intramural urethral bulking aims to augment the urethral wall and increase the urethral closure force.

Result type

Interventional procedures guidance

Published

23 November 2005

Evidence-based recommendations on photodynamic therapy (PDT) for localised inoperable endobronchial cancer (non-small-cell lung cancer). This involves injecting a photosensitising agent into the body that is activated by laser light to destroy the cancerous tissue.

Result type

Interventional procedures guidance

Published

23 November 2005

This guideline covers specific aspects of respiratory support (for example, oxygen supplementation, assisted ventilation, treatment of some respiratory disorders, and aspects of monitoring) for preterm babies in hospital.

Result type

NICE guideline

Published

3 April 2019

Evidence-based recommendations on needle fasciotomy for Dupuytren's contracture. This involves cutting one or more fibrous bands using a blade or a bevel of a needle.

Result type

Interventional procedures guidance

Published

25 February 2004

Evidence-based recommendations on interstitial laser therapy for breast cancer. This involves using laser energy to destroying the cancer cells.

Result type

Interventional procedures guidance

Published

22 September 2004

Evidence-based recommendations on cryoablation for atrial fibrillation in association with other cardiac surgery. This involves using a probe to freeze the heart tissue to scar it and interrupt the abnormal electrical signals.

Result type

Interventional procedures guidance

Published

25 May 2005

This quality standard covers assessing and managing motor neurone disease, including care, support and planning after diagnosis. It describes high-quality care in priority areas for improvement.

Result type

Quality standard

Published

27 July 2016

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Evidence-based recommendations on daratumumab (Darzalex) with lenalidomide and dexamethasone for untreated multiple myeloma in adults, when a stem cell transplant is unsuitable.

Result type

Technology appraisal guidance

Published

25 October 2023

Evidence-based recommendations on fruquintinib (Fruzaqla) for previously treated metastatic colorectal cancer in adults.

Result type

Technology appraisal guidance

Published

23 July 2025

This indicator covers patient adherence to nebulised therapy in cystic fibrosis. It measures outcomes that reflect the quality of care or processes linked by evidence to improved outcomes

Result type

Network / system level indicators

Published

30 September 2023

Evidence-based recommendations on partial left ventriculectomy. This involves reducing the size of a part of the heart so it can pump blood more efficiently.

Result type

Interventional procedures guidance

Published

25 February 2004

Evidence-based recommendations on percutaneous cryotherapy for renal tumours. This involves inserting instruments that apply cold temperatures into the tumour to destroy the cancer cells.

Result type

Interventional procedures guidance

Published

27 July 2011

Evidence-based recommendations on balloon catheter dilation of paranasal sinus ostia for chronic sinusitis. This involves gently inflating a small balloon, which is introduced through the nose via a flexible tube, to help keep the sinus passages open and unobstructed.

Result type

Interventional procedures guidance

Published

24 September 2008

NICE has developed a medtech innovation briefing (MIB) on eazyplex SuperBug kits for detecting carbapenemase-producing organisms .

Result type

Medtech innovation briefing

Published

7 February 2017

Evidence-based recommendations on extracorporeal shockwave therapy for refractory greater trochanteric pain syndrome. This involves using a machine to deliver sound waves to the painful area to stimulate healing.

Result type

Interventional procedures guidance

Published

26 January 2011

Evidence-based recommendations on botulinum toxin type A injections into the urethral sphincter for idiopathic chronic non-obstructive urinary retention. This involves injecting botulinum toxin type A into the urethral sphincter.

Result type

Interventional procedures guidance

Published

28 June 2023

Evidence-based recommendations on arthroscopic knee washout, with or without debridement, for the treatment of osteoarthritis. This involves flushing the joint with fluid, which is introduced through small incisions in the knee.

Result type

Interventional procedures guidance

Published

22 August 2007

Summary of the evidence on netupitant/palonosetron to prevent chemotherapy induced nausea and vomiting to inform local NHS planning and decision-making

Result type

Evidence summary

Published

1 March 2016

Evidence-based recommendations on percutaneous retroperitoneal endoscopic necrosectomy. This involves inserting a thin telescope through a small cut in the side above the hip and using it to wash out and remove the dead tissue.

Result type

Interventional procedures guidance

Published

23 March 2011

Evidence-based recommendations on microwave ablation of hepatocellular carcinoma. This involves using heat from microwave energy to destroy the cancer cells.

Result type

Interventional procedures guidance

Published

28 March 2007

Evidence-based recommendations on radiofrequency ablation for symptomatic interdigital (Morton’s) neuroma. This involves using pulses of radiofrequency heat energy to damage the nerve, with the aim of reducing pain.

Result type

Interventional procedures guidance

Published

16 December 2015

Evidence-based recommendations on lead-I electrocardiogram (ECG) devices (imPulse, Kardia Mobile, MyDiagnostick and Zenicor-ECG) for detecting symptomatic atrial fibrillation using single time point testing in primary care.

Result type

HealthTech guidance

Published

8 May 2019

Evidence-based recommendations on fetoscopic prenatal repair of open neural tube defects in the fetus. This involves keyhole surgery through the woman’s abdomen to close the gap in the baby’s spine.

Result type

Interventional procedures guidance

Published

29 January 2020

Evidence-based recommendations on percutaneous thoracic duct embolisation for persistent chyle leak. In this procedure, under general anaesthesia, ultrasound and X-rays are used to create an image of the thoracic duct and find the leak. Then, using a needle, a tube is inserted through the abdominal wall (percutaneous) and guided into the thoracic duct. Small metal coils and medical glue are inserted through the tube and used to plug the leak (embolisation). The aim is to stop the leak.

Result type

Interventional procedures guidance

Published

5 April 2023

Evidence-based recommendations on caval valve implantation for tricuspid regurgitation in adults. This involves implanting valves into 1 or both caval veins without disturbing the tricuspid valve.

Result type

Interventional procedures guidance

Published

21 August 2024