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Showing 2601 to 2650 of 4090 results for patient

  1. trublood-prostate for triaging and diagnosing people with prostate cancer symptoms (MIB268)

    NICE has developed a medtech innovation briefing (MIB) on trublood-prostate for triaging and diagnosing people with prostate cancer symptoms .

    Medtech innovation briefing
    Published
    13 July 2021

  2. Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza (TA158)

    Evidence-based recommendations on oseltamivir (Tamiflu), amantadine (Lysovir or Symmetrel) or zanamivir (Relenza) to prevent influenza (flu).

    Technology appraisal guidance
    Published
    24 September 2008
    View recommendations

    Sections for TA158

  3. Coeliac disease: recognition, assessment and management (NG20)

    This guideline covers the recognition, assessment and management of coeliac disease in children, young people and adults.

    NICE guideline
    Published
    2 September 2015
    View recommendations

    Sections for NG20

  4. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management (CG184)

    This guideline covers investigating and managing gastro-oesophageal reflux disease (GORD) and dyspepsia in people aged 18 and over. It aims to improve the treatment of GORD and dyspepsia by making detailed recommendations on Helicobacter pylori eradication, and specifying when to consider laparoscopic fundoplication and referral to specialist services.

    Clinical guideline
    Last updated
    18 October 2019
    View recommendations

    Sections for CG184

  5. PLASMA system with button electrode for electrovaporisation of the prostate (MIB274)

    NICE has developed a medtech innovation briefing (MIB) on PLASMA system with button electrode for electrovaporisation of the prostate .

    Medtech innovation briefing
    Published
    31 August 2021

  6. moorLDLS-BI for burn depth assessment (MIB251)

    NICE has developed a medtech innovation briefing (MIB) on moorLDLS-BI for burn depth assessment .

    Medtech innovation briefing
    Published
    9 February 2021

  7. Anaesthesia: What is the clinical and cost effectiveness of regional versus general anaesthesia on postoperative morbidity in people with hip fracture?

    does not reflect current practice. In addition, in most of the studies the patients are sedated before regional anaesthesia is...

    Research recommendation
    Published
    3 February 2023

  8. NICE Listens

    NICE Listens is our programme of deliberative public engagement. It's used to give us an understanding of public opinion on moral, ethical and social value issues.

  9. Pharmacological treatments for headache prophylaxis to aid withdrawal treatment in medication overuse headache:- Does a course of steroid treatment or pharmacological treatments used for headache prophylaxis help people with medication overuse headaches withdraw from medication?

    acute medication use, proportion of patients who no longer have suspected medication overuse headache, change in...

    Research recommendation
    Published
    9 June 2015

  10. Antimicrobials evaluation panel members

    Read the biographies for all members of the NICE antimicrobial evaluation committee.

  11. Antimicrobials evaluation panel members

    Read the biographies for all members of the NICE antimicrobial evaluation committee.

  12. Inducing labour (NG207)

    This guideline covers the circumstances for inducing labour, methods of induction, assessment, monitoring, pain relief and managing complications. It aims to improve advice and care for pregnant women who are thinking about or having induction of labour.

    NICE guideline
    Published
    4 November 2021
    View recommendations

    Sections for NG207

  13. Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy (TA1040)

    Evidence-based recommendations on olaparib (Lynparza) for BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy in adults.

    Technology appraisal guidance
    Published
    12 February 2025
    View recommendations

    Sections for TA1040

  14. CaRi-Heart for predicting cardiac risk in suspected coronary artery disease: early value assessment (HTG663)

    Early value assessment (EVA) guidance on CaRi-Heart for predicting cardiac risk in suspected coronary artery disease.

    HealthTech guidance
    Published
    9 March 2023
    View recommendations

    Sections for HTG663

  15. Endovascular aneurysm sealing for abdominal aortic aneurysm (IPG547)

      March 2019: We have withdrawn the guidance because the CE mark for the Nellix Endovascular Aneurysm Sealing (EVAS) System has been withdrawn. Endologix is recalling unused stock. The MHRA recommends enhanced patient surveillance (see MDA/2019/002) because of a high risk of the graft failing beyond 2 years after implantation.

    Withdrawn guidance

  16. Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe emphysema is inadequate in quantity and quality. Therefore the procedure should only be used in the context of  research .

    evaluate safety and efficacy in the short and long term and include details of patient selection. NICE may update the guidance on...

    Research recommendation
    Published
    15 November 2019

  17. Percutaneous transluminal renal sympathetic denervation for resistant hypertension should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    controlled trials or analysis of registry data. It should report details of patient selection, technique used and long-term outcomes....

    Research recommendation
    Published
    27 April 2023

  18. For people with favourable aneurysm morphology needing an EVAR as a primary procedure, evidence on the safety of using endoanchoring systems is adequate. However, evidence on efficacy is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should report details of patient selection and include longerterm outcomes. Source...

    Research recommendation
    Published
    1 June 2022

  19. For people with mild or moderate tricuspid regurgitation, evidence on the safety and efficacy of transcatheter tricuspid valve annuloplasty is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    4 August 2022

  20. For people with mild or moderate tricuspid regurgitation, evidence on the safety and efficacy of transcatheter tricuspid valve leaflet repair is inadequate in quantity and quality. Therefore, for these people, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    5 August 2022

  21. Hearing loss in adults: assessment and management (NG98)

    This guideline covers some aspects of assessing and managing hearing loss in primary, community and secondary care. It aims to improve the quality of life for adults with hearing loss by advising healthcare staff on assessing hearing difficulties, managing earwax and referring people for audiological or specialist assessment and management.

    NICE guideline
    Last updated
    2 October 2023
    View recommendations

    Sections for NG98

  22. Remdesivir and tixagevimab plus cilgavimab for treating COVID-19 (TA971)

    Evidence-based recommendations on remdesivir (Veklury) and tixagevimab plus cilgavimab (Evusheld) for treating COVID-19.

    Technology appraisal guidance
    Published
    8 May 2024
    View recommendations

    Sections for TA971

  23. Information for family members or carers: What information and support are needed by family members or carers of people having treatment with an opioid, benzodiazepine, Z‑drug, antidepressant or gabapentinoid?

    of the evidence and the committee's discussion are in evidence review A: patient information and support. Source guidance details Comes...

    Research recommendation
    Published
    11 May 2022

  24. Evidence on the safety and efficacy of radiofrequency ablation for palliation of painful spinal metastases is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    encourages further research into the procedure. This should report details of patient selection, type of tumour and interventional...

    Research recommendation
    Published
    5 May 2023

  25. Middle meningeal artery embolisation for chronic subdural haematomas should be used only in research. Find out what only in research means on the NICE interventional procedures guidance page.

    trials or other suitably designed studies. It should report details of patient selection, technique used, rebleeding, functional...

    Research recommendation
    Published
    3 May 2024

  26. Rapid genetic testing:- Research is recommended to determine the benefits and harms of creating rapid access to genetic testing for people with newly diagnosed breast cancer. This research should address the optimum model for service delivery and organisation, the clinical and cost effectiveness of such a change, uptake outcomes and patients' experience. [new 2013]

    clinical and cost effectiveness of such a change, uptake outcomes and patients' experience. [new 2013] Any explanatory notes(if...

    Research recommendation
    Published
    9 June 2015

  27. Memokath-028, 044 and 045 stents for urethral obstruction (MIB123)

    NICE has developed a medtech innovation briefing (MIB) on Memokath-028, 044 and 045 stents for urethral obstruction .

    Medtech innovation briefing
    Published
    2 October 2017

  28. Chronic wounds: advanced wound dressings and antimicrobial dressings (ESMPB2)

    Summary of the evidence on advanced wound dressings and antimicrobial dressings for managing chronic wounds to inform local NHS planning and decision-making

    Evidence summary
    Published
    30 March 2016

  29. Organisation of care:- What is the clinical and cost effectiveness of alternative approaches to organising primary care compared with usual care for people with multimorbidity?

    primary care for people with multimorbidity would be of value in defined patient groups (for example, people with multimorbidity who...

    Research recommendation
    Published
    18 October 2016

  30. Panitumumab in combination with chemotherapy for the treatment of metastatic colorectal cancer (terminated appraisal) (TA240)

    NICE is unable to recommend panitumumab with 5-fluorouracil, folinic acid and irinotecan (FOLFIRI) for previously treated metastatic colorectal cancer in adults. This is because Amgen did not provide an evidence submission.

    Technology appraisal guidance
    Last updated
    29 March 2017

    Sections for TA240

  31. AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas (MIB294)

    NICE has developed a medtech innovation briefing (MIB) on AMBLor for identifying low-risk non-ulcerated early-stage cutaneous melanomas .

    Medtech innovation briefing
    Published
    5 May 2022

  32. Simple home test prevents thousands of unnecessary bowel cancer referrals

    A simple home test is sparing thousands of people from unnecessary hospital investigations for bowel cancer, while helping them get faster answers about whether they have the disease – with new data showing the impact of NICE's recommendation to use the test.

    News
    Last updated
    6 February 2026

  33. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve annuloplasty is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    4 August 2022

  34. Information needs for children and young people:- during their care pathway to diagnosis of food allergy:- What do children and young people with IgE-mediated food allergy and their parents or carers want to know during the process of diagnosis and how is this demand best met?

    Any explanatory notes(if applicable) Why this is important:- The patient journey to diagnosis, through testing, can last for several...

    Research recommendation
    Published
    9 June 2015

  35. Does a multidisciplinary team agreed approach to weaning from continuous positive airway pressure improve weaning times and result in stopping continuous positive airway pressure for people with COVID-19 and acute respiratory failure?

    weaning C: • standard care• different multidisciplinary team approaches O:• patient experience• symptom improvement• length of time to...

    Research recommendation
    Published
    12 November 2021

  36. Causes of unwitnessed falls among older inpatients:- What are the causes of unwitnessed falls among older inpatients?

    unwitnessed. Although staff may deduce reasons for the fall and/or the patient (if able and if asked) may describe their own perception...

    Research recommendation
    Published
    9 June 2015

  37. Evidence on the safety of repetitive short-pulse transscleral cyclophotocoagulation for glaucoma shows no major safety concerns. Evidence on efficacy is inadequate in quality. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE website.

    comparing the procedure with standard care. It should report details of patient selection, particularly whether the glaucoma is...

    Research recommendation
    Published
    16 August 2021

  38. For people with severe and symptomatic tricuspid regurgitation, evidence on the efficacy of transcatheter tricuspid valve leaflet repair is limited in quantity and quality. Evidence on its safety shows there are serious but well-recognised complications. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should include details of patient selection, including the type and severity of...

    Research recommendation
    Published
    5 August 2022

  39. For people with unfavourable aneurysm morphology needing an endovascular aortic aneurysm repair (EVAR) as a primary procedure, or for people with an existing EVAR who need a secondary procedure, evidence on the safety of using endoanchoring systems is adequate. Evidence on efficacy is limited in quantity and quality. Therefore, for these people, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    explanatory notes(if applicable) Further research should report details of patient selection and include longerterm outcomes. Source...

    Research recommendation
    Published
    1 June 2022

  40. Evidence on the safety and efficacy of supercapsular percutaneously assisted total hip arthroplasty for osteoarthritis is limited in quality and quantity. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    standard approaches to total hip arthroplasty. It should report details of patient selection, short-term outcomes and long-term...

    Research recommendation
    Published
    1 June 2022

  41. Evidence on the safety of ab interno canaloplasty for open-angle glaucoma shows no major safety concerns. Evidence on the efficacy is limited in quality and quantity, particularly in the long term. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    notes(if applicable) Further research should report: - details of patient selection, including concurrent procedures, severity of...

    Research recommendation
    Published
    12 December 2022

  42. Evidence on the safety and efficacy of percutaneous thoracic duct embolisation for persistent chyle leak is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    embolisation for persistent chyle leak. Research should include details of patient selection, size and position of the leak, approaches...

    Research recommendation
    Published
    5 May 2023

  43. Complicated urinary tract infections: ceftolozane/tazobactam (ESNM74)

    Summary of the evidence on ceftolozane/tazobactam for treating complicated urinary tract infections to inform local NHS planning and decision-making

    Evidence summary
    Published
    9 June 2016

  44. NICE encourages further research and data collection on endoscopic full thickness removal of non-lifting colonic polyps and may update the guidance on publication of further evidence. This should include safety and efficacy outcomes such as perforation, bleeding, the need for immediate re-intervention, inadequate resection and longer-term follow-up of patients found to have malignant disease.

    immediate re-intervention, inadequate resection and longer-term follow-up of patients found to have malignant disease. Any explanatory...

    Research recommendation
    Published
    12 October 2018

  45. Non-alcoholic fatty liver disease (NAFLD): assessment and management (NG49)

    This guideline covers how to identify the adults, young people and children with non-alcoholic fatty liver disease (NAFLD) who have advanced liver fibrosis and are most at risk of further complications. It outlines the lifestyle changes and pharmacological treatments that can manage NAFLD and advanced liver fibrosis.

    NICE guideline
    Published
    6 July 2016
    View recommendations

    Sections for NG49

  46. Crovalimab for treating paroxysmal nocturnal haemoglobinuria in people 12 years and over (TA1019)

    Evidence-based recommendations on crovalimab (Piasky) for paroxysmal nocturnal haemoglobinuria in people 12 years and over.

    Technology appraisal guidance
    Published
    20 November 2024
    View recommendations

    Sections for TA1019

  47. Evidence on the safety of focal therapy using high-intensity focused ultrasound for localised prostate cancer is adequate, but evidence on its efficacy is limited. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page.

    include registry data or randomised trials. It should include details of patient selection, including size and classification of tumour,...

    Research recommendation
    Published
    5 May 2023

  48. Evidence on the safety and efficacy of YAG laser vitreolysis for symptomatic vitreous floaters is inadequate in quality and quantity. Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    powered randomised controlled trials. Research should report details of patient selection (including type, size and location of...

    Research recommendation
    Published
    7 November 2022

  49. Evidence on the safety and efficacy of permanent His-bundle pacemaker implantation for treating heart failure is inadequate in quality and quantity.Therefore, this procedure should only be used in the context of research. Find out what only in research means on the NICE interventional procedures guidance page.

    randomised controlled trials or registry data. It should report details of patient selection. Outcomes should include quality of life...

    Research recommendation
    Published
    10 August 2021

  50. Evidence on the safety of pressurised intraperitoneal aerosol chemotherapy for peritoneal carcinomatosis shows that this procedure can cause serious but well-recognised side effects. Evidence on its efficacy is inadequate in quality. Therefore, this procedure should only be used in the context of research. Find out what  only in research means on the NICE website .

    aerosol chemotherapy with standard care. Studies should report details of patient selection including type of tumour, the chemotherapy...

    Research recommendation
    Published
    22 January 2021