Updating results

Evidence on the progression of X-linked hypophosphataemia (XLH) over time and the long-term benefits of burosumab would also be valuable.

Recommendation ID HST8/3 Question Evidence on the progression of X-linked hypophosphataemia (XLH) over time and the long-term benefits of

Research recommendation Published March 2019

Better Together – ASSIST Hospital Discharge Scheme

Shared learning Published October 2016 Last updated March 2019

Pembrolizumab for treating recurrent or metastatic squamous cell carcinoma of the head and neck after platinum-based chemotherapy (terminated appraisal) (TA570)

NICE is unable to make a recommendation about the use in the NHS of pembrolizumab (Keytruda) for treating recurrent or metastatic squamous cell carcinoma of the

Technology appraisal guidance Published March 2019

Key therapeutic topic consultations

Consultation for the 2019 update Key therapeutic topics 2019 update: final list of topics (September 2018) PDF Responses to comments received

Published March 2019

Pertuzumab for adjuvant treatment of HER2-positive early stage breast cancer (TA569)

Evidence-based recommendations on pertuzumab (Perjeta) for adjuvant treatment (with trastuzumab and chemotherapy) of HER2-positive early stage breast cancer

Technology appraisal guidance Published March 2019

Key therapeutic topics

Medicines optimisation: key therapeutic topics summarise the evidence-base on topics identified to support medicines optimisation, but are not formal...

Published March 2019

Brigatinib for treating ALK-positive advanced non-small-cell lung cancer after crizotinib (TA571)

Evidence-based recommendations on brigatinib (Alunbrig) for treating ALK-positive advanced non-small-cell lung cancer in adults who have already had crizotinib

Technology appraisal guidance Published March 2019

NICE impact: mental health

How NICE recommendations are being used to improve mental health

Published March 2019

The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore further research is recommended. Any research should measure the effect of treatment using preference-based measures (such as use of the EQ-5D questionnaire).

Recommendation ID TA556/2 Question The health-related quality-of-life evidence of patients with perianal fistulas is also lacking, therefore

Research recommendation Published March 2019

Committee D members

Find out more about NICE technology appraisals advisory committee D members

Published March 2019

Early and locally advanced breast cancer

Everything NICE has said on diagnosing and treating early and locally advanced breast cancer in an interactive flowchart

NICE Pathway Published May 2011 Last updated March 2019

Bronchiolitis in children

Everything NICE has said on diagnosing and managing bronchiolitis in children in an interactive flowchart

NICE Pathway Published June 2015 Last updated March 2019

Eating disorders

Everything NICE has said on identifying and managing eating disorders in people 8 years and over in an interactive flowchart

NICE Pathway Published May 2013 Last updated March 2019

Upper aerodigestive tract cancer

Everything NICE has said on assessing and managing upper aerodigestive tract cancer in young people and adults in an interactive flowchart

NICE Pathway Published February 2016 Last updated March 2019

Further research should include details of patient selection, durability and the incidence of complications. Outcomes should be published.

Recommendation ID IPG642/1 Question Further research should include details of patient selection, durability and the incidence of complications

Research recommendation Published March 2019

Further research should report details of patient selection, nodule size and position, and whether the nodule is cystic.

Recommendation ID IPG643/1 Question Further research should report details of patient selection, nodule size and position, and whether the

Research recommendation Published March 2019

Kendall DL for ECG monitoring in people having cardiac surgery (MIB177)

Advice on Kendall DL for ECG monitoring in people having cardiac surgery to aid local decision making

Medtech innovation briefing Published March 2019

Life sciences

Support for industry to engage with NICE during all stages of health technology development

Published March 2019

NICE celebrates its 20th anniversary

Organisation was founded in April 1999 to improve outcome for health service users

News Published March 2019

Diagnostics Advisory Committee members

Find out more about the NICE Diagnostics Advisory Committee members by reading their biographies. Dr Mark Kroese MB, ChB, DPH, FFPH, FRCP(Ed)

Published March 2019

History of NICE

1999 Creation of NICE The National Institute for Clinical Excellence became a legal entity in April. Our aim was to create consistent guidelines

Published March 2019

Delirium

Everything NICE has said on preventing and managing delirium in adults presenting to hospital or in long-term care in an interactive flowchart

NICE Pathway Published September 2012 Last updated March 2019

Delirium: prevention, diagnosis and management (CG103)

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and preventing onset. It aims to improve diagnosis of delirium and reduce hospital stays and complications.

Clinical guideline Published July 2010 Last updated March 2019

Gender pay gap report

The latest gender pay gap data from NICE

Published March 2019

Abatacept for treating psoriatic arthritis after DMARDs (terminated appraisal) (TA568)

NICE is unable to make a recommendation on abatacept (Orencia) for treating psoriatic arthritis after DMARDs in adults because of no evidence submission from

Technology appraisal guidance Published March 2019

Radially emitting laser fibre treatment of an anal fistula (IPG644)

Evidence-based recommendations on radially emitting laser fibre treatment of an anal fistula in adults

Interventional procedures guidance Published March 2019

Timelines for charging: highly specialised technologies

Charging points and timescales for our highly specialised technologies (HST) guidance.

Published March 2019

Timelines for charging: technology appraisals

Charging points and timescales for our technology appraisal (TA) guidance.

Published March 2019

Committee B members

Find out more about the NICE technology appraisal advisory committee B members

Published March 2019

Tisagenlecleucel for treating relapsed or refractory diffuse large B-cell lymphoma after 2 or more systemic therapies (TA567)

Evidence-based recommendations on tisagenlecleucel therapy (Kymriah) for treating relapsed or refractory diffuse large B-cell lymphoma in adults

Technology appraisal guidance Published March 2019

Spondyloarthritis

Everything NICE has said on diagnosing and managing spondyloarthritis in people aged 16 and over in an interactive flowchart

NICE Pathway Published February 2017 Last updated March 2019

Thousands set to benefit from blood pressure treatment under new NICE guidance

NICE has published its draft updated guideline on the diagnosis and treatment of high blood pressure (hypertension) for public consultation.

News Published March 2019

NICE Student Champion Scheme resources

NICE Student Champion Scheme resources

Published March 2019

Aortic aneurysms

Everything NICE has said on aortic aneurysms in an interactive flowchart

NICE Pathway Published March 2014 Last updated March 2019

Selective dorsal rhizotomy treatment to reduce spasticity:- What is the clinical and cost effectiveness of selective dorsal rhizotomy compared with intrathecal baclofen to reduce spasticity in adults with cerebral palsy?

Recommendation ID NG119/2 Question Selective dorsal rhizotomy treatment to reduce spasticity:- What is the clinical and cost effectiveness

Research recommendation Published March 2019

Splinting to improve or maintain posture or function:- What is the optimum regimen for splints applied to the upper limb in adults with cerebral palsy to improve or maintain posture or function?

Recommendation ID NG119/5 Question Splinting to improve or maintain posture or function:- What is the optimum regimen for splints applied

Research recommendation Published March 2019

Detection and management of respiratory disorders in primary and community care:- Can detection and management of respiratory disorders in adults with cerebral palsy be improved in primary and community care?

Recommendation ID NG119/3 Question Detection and management of respiratory disorders in primary and community care:- Can detection and management

Research recommendation Published March 2019

Augmentative and alternative communication systems:- Are augmentative and alternative communication systems clinically and cost effective in promoting  communication for adults with cerebral palsy who have communication difficulties?

Recommendation ID NG119/6 Question Augmentative and alternative communication systems:- Are augmentative and alternative communication systems

Research recommendation Published March 2019

Prophylactic antibiotics for respiratory disorders:- Are prophylactic antibiotics clinically and cost effective in the management of respiratory symptoms in adults with cerebral palsy with significant respiratory comorbidity?

Recommendation ID NG119/4 Question Prophylactic antibiotics for respiratory disorders:- Are prophylactic antibiotics clinically and cost

Research recommendation Published March 2019

A new model for clinical decision making in patients with multimorbidity

Multimorbidity needs a new model of treatment, the authors explain why and how

News Published March 2019

890 more children and adults eligible for cochlear implants on the NHS each year

Hundreds more people with severe to profound deafness will be eligible for cochlear implants each year, due to updated NICE guidance

News Published March 2019

Frequency of follow-up imaging:- What is the clinical and cost effectiveness of 6-monthly imaging for 3 years for people with recurrent calcium renal or ureteric stones?

Recommendation ID NG118/4 Question Frequency of follow-up imaging:- What is the clinical and cost effectiveness of 6-monthly imaging for

Research recommendation Published March 2019