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Guidance programme

Advice programme

Showing 4551 to 4600 of 8897 results

  1. Assessment at home to improve hospital discharge success rates:- How effective are home assessment interventions and approaches designed to improve hospital discharge outcomes?

    Recommendation ID NG27/5 Question Assessment at home to improve hospital discharge success rates:- How effective are home assessment interventions

  2. Assessment models for different groups of children and young people:- How effective are the models currently used for assessing the needs of, and level of risk for, children and young people from different population groups who display harmful sexual behaviour?

    Recommendation ID NG55/5 Question Assessment models for different groups of children and young people:- How effective are the models currently

  3. Assessment tools for health promotion:- What are the most effective tools to determine the health promotion needs of people in prison?

    Recommendation ID NG57/4 Question Assessment tools for health promotion:- What are the most effective tools to determine the health promotion

  4. A trial comparing the long-term effectiveness (beyond 24 weeks) of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate and placebo would be beneficial. It should collect utility data as well as walking distance outcomes.

    Recommendation ID TA223/1 Question A trial comparing the long-term effectiveness (beyond 24 weeks) of cilostazol, naftidrofuryl oxalate

  5. Prevention of prolonged pregnancy: At what gestational age should induction of labour be offered in the subgroups of women who may be more likely to experience adverse outcomes if pregnancy continues?

    Recommendation ID NG207/01 Question Prevention of prolonged pregnancy: At what gestational age should induction of labour be offered in

  6. Anti-reflux therapy as a treatment for idiopathic pulmonary fibrosis:- Is anti-reflux therapy an effective treatment for idiopathic pulmonary fibrosis?

    Recommendation ID CG163/5 Question Anti-reflux therapy as a treatment for idiopathic pulmonary fibrosis:- Is anti-reflux therapy an effective

  7. What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations in the prevention of surgical site infection when applied to the skin before incision?

    Recommendation ID NG125/3 Question What is the clinical and cost effectiveness of chlorhexidine in alcohol at different concentrations

  8. What is the clinical and cost effectiveness of a block and replace regimen compared with a titration regimen of antithyroid drugs for Graves' disease?

    Recommendation ID NG145/8 Question What is the clinical and cost effectiveness of a block and replace regimen compared with a titration

  9. Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid drugs?

    Recommendation ID NG145/3 Question Are there subgroups of people with Graves' disease who have a particularly good response to antithyroid

  10. What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for people with T3 thyrotoxicosis due to Graves' disease?

    Recommendation ID NG145/6 Question What is the clinical and cost effectiveness of different durations of antithyroid drug regimens for

  11. Decision-to-birth interval (category 2 urgency): A prospective study to determine whether the decision-to-birth interval has an impact on maternal and neonatal outcomes when there is a category 2 level of urgency for caesarean birth.

    Recommendation ID NG192/03 Question Decision-to-birth interval (category 2 urgency): A prospective study to determine whether the decision-to-birth

  12. Augmentative and alternative communication systems:- Are augmentative and alternative communication systems clinically and cost effective in promoting  communication for adults with cerebral palsy who have communication difficulties?

    Recommendation ID NG119/6 Question Augmentative and alternative communication systems:- Are augmentative and alternative communication

  13. Awareness of risk among black, Asian and other minority ethnic groups: Are black, Asian and other minority ethnic groups aware that they are at the same risk of type 2 diabetes and mortality at a lower BMI, compared with the white population?

    Recommendation ID CG189/10 Question Awareness of risk among black, Asian and other minority ethnic groups: Are black, Asian and other minority

  14. Duration of risk of radiotherapy in people with cancer and COVID-19: Are people who have had radiotherapy recently (that is, within the 4 weeks preceding a diagnosis of COVID-19) at increased risk of poor outcomes from COVID-19 compared with those who had radiotherapy less recently?

    Recommendation ID NG162/2 Question Duration of risk of radiotherapy in people with cancer and COVID-19: Are people who have had radiotherapy

  15. Duration of risk of systemic anticancer treatment in people with cancer and COVID-19: Are people who have had SACT recently (that is, within the 4 weeks preceding a diagnosis of COVID-19) at increased risk of poor outcomes from COVID-19 compared with those who had SACT less recently?

    Recommendation ID NG161/2 Question Duration of risk of systemic anticancer treatment in people with cancer and COVID-19: Are people who

  16. Prophylactic antibiotics for respiratory disorders:- Are prophylactic antibiotics clinically and cost effective in the management of respiratory symptoms in adults with cerebral palsy with significant respiratory comorbidity?

    Recommendation ID NG119/4 Question Prophylactic antibiotics for respiratory disorders:- Are prophylactic antibiotics clinically and cost

  17. Are psychological interventions effective for treating moderate to severe anxiety disorders (including obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder and social anxiety disorder) in pregnancy?

    Recommendation ID CG192/5 Question Are psychological interventions effective for treating moderate to severe anxiety disorders (including

  18. Are psychosocial interventions clinically and cost effective when compared with standard care for people with psychosis and coexisting substance misuse?

    Recommendation ID CG120/6 Question Are psychosocial interventions clinically and cost effective when compared with standard care for people

  19. Standardised criteria for hospital discharge:- Are standardised criteria for hospital discharge clinically and cost effective in specific medical emergencies? [See the evidence review on standardised discharge criteria.]

    Recommendation ID NG94/14 Question Standardised criteria for hospital discharge:- Are standardised criteria for hospital discharge clinically

  20. Are the Department of Health's 'Let's get moving' physical activity care pathway and the general practice physical activity questionnaire (GPPAQ) both commonly used in primary care? How do primary care practitioners view GPPAQ and, if they do not use it, why not?

    Recommendation ID PH44/7 Question Are the Department of Health's 'Let's get moving' physical activity care pathway and the general practice

  21. Are there effective long-term pharmacological interventions to prevent the onset of type 2 diabetes that can be recommended postnatally for women who have been diagnosed with gestational diabetes?

    Recommendation ID NG3/5 Question Are there effective long-term pharmacological interventions to prevent the onset of type 2 diabetes that

  22. Step 1 treatment: Are there subgroups of people with hypertension who should start on dual therapy?

    Recommendation ID NG136/04 Question Step 1 treatment: Are there subgroups of people with hypertension who should start on dual therapy

  23. What is the clinical and cost effectiveness, post treatment and at longer-term follow‑up, of behavioural activation compared with other psychological therapies in children aged 5 to 11 years and young people aged 12 to 18 years with mild or moderate to severe depression?

    Recommendation ID NG134/5 Question What is the clinical and cost effectiveness, post treatment and at longer-term follow‑up, of behavioural

  24. Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual care/advice for children with faltering growth?

    Recommendation ID NG75/3 Question Behavioural interventions:- What is the effectiveness of behavioural interventions compared with usual

  25. Behaviour change methods and resources:- What behaviour change methods and resources (such as phone apps, leaflets and messaging) help dental teams to provide people with support to improve their oral health?

    Recommendation ID NG30/3 Question Behaviour change methods and resources:- What behaviour change methods and resources (such as phone apps

  26. Bilateral cervicosacropexy (CESA) or vaginosacropexy (VASA) using mesh for pelvic organ prolapse

    Recommendation ID IPG669/1 Question Bilateral cervicosacropexy (CESA) or vaginosacropexy (VASA) using mesh for pelvic organ prolapse

  27. Bisphosphonates for the prevention of bone disease:- What is the effectiveness of monthly zoledronic acid given indefinitely compared with zoledronic acid given for a fixed duration in patients with myeloma?

    Recommendation ID NG35/5 Question Bisphosphonates for the prevention of bone disease:- What is the effectiveness of monthly zoledronic

  28. Bladder management strategies:- What are the long-term risks and effects on quality of life of different bladder management strategies for lower urinary tract dysfunction in people with neurological disease?

    Recommendation ID CG148/4 Question Bladder management strategies:- What are the long-term risks and effects on quality of life of different

  29. Bone mineral density (BMD) with FRAX:- What is the added prognostic value of BMD in the assessment of fracture risk with FRAX?

    Recommendation ID CG146/4 Question Bone mineral density (BMD) with FRAX:- What is the added prognostic value of BMD in the assessment of

  30. What is the clinical utility of bone turnover markers in the diagnosis and management of primary hyperparathyroidism?

    Recommendation ID NG132/1 Question What is the clinical utility of bone turnover markers in the diagnosis and management of primary...

  31. Botulinum toxin type A:- What is the clinical and cost effectiveness of botulinum toxin type A when used routinely or according to clinical need in children and young people who are at Gross Motor Function Classification System (GMFCS) level I, II or III?

    Recommendation ID CG145/3 Question Botulinum toxin type A:- What is the clinical and cost effectiveness of botulinum toxin type A when

  32. Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe emphysema is inadequate in quantity and quality. Therefore the procedure should only be used in the context of  research .

    Recommendation ID IPG652/1 Question Current evidence on the safety and efficacy of bronchoscopic thermal vapour ablation for upper-lobe

  33. Cachexia interventions: - A cohort study followed by phase II and III studies should be undertaken in people with pancreatic cancer and cachexia or pre-cachexia, to compare cachexia assessment methods and anti-cachexia interventions with standard care.

    Recommendation ID NG85/2 Question Cachexia interventions: - A cohort study followed by phase II and III studies should be undertaken in

  34. Core outcome set for studies of management of Lyme disease:- Can a core outcome set be developed for clinical trials of management of Lyme disease?

    Recommendation ID NG95/1 Question Core outcome set for studies of management of Lyme disease:- Can a core outcome set be developed for

  35. Safety, prognostic and predictive biomarkers: Can biomarkers be used for risk stratification and treatment planning for people with melanoma?

    Recommendation ID NG14/02 Question Safety, prognostic and predictive biomarkers: Can biomarkers be used for risk stratification and treatment

  36. Monitoring and response biomarkers: Can biomarkers accurately classify recurrence, progression and response to treatment?

    Recommendation ID NG14/01 Question Monitoring and response biomarkers: Can biomarkers accurately classify recurrence, progression and response

  37. Detection and management of respiratory disorders in primary and community care:- Can detection and management of respiratory disorders in adults with cerebral palsy be improved in primary and community care?

    Recommendation ID NG119/3 Question Detection and management of respiratory disorders in primary and community care:- Can detection and

  38. Can rapid microbiological diagnosis of hospital-acquired pneumonia reduce the use of xtendedspectrum antibiotic therapy, without adversely affecting outcomes?

    Recommendation ID CG191/4 Question Can rapid microbiological diagnosis of hospital-acquired pneumonia reduce the use of xtendedspectrum

  39. Stroke risk assessment: Can routine data from UK primary care databases clarify stroke risk in people with atrial fibrillation according to baseline risk factors and treatment?

    Recommendation ID NG196/7 Question Stroke risk assessment: Can routine data from UK primary care databases clarify stroke risk in people

  40. Can vitamin D slow down the progression of disability in Multiple Sclerosis (MS)?

    Recommendation ID CG186/5 Question Can vitamin D slow down the progression of disability in Multiple Sclerosis (MS)? Any explanatory

  41. Weight loss for managing pelvic floor dysfunction: Can weight loss reduce symptoms of pelvic floor dysfunction in women who are overweight or obese?

    Recommendation ID NG210/11 Question Weight loss for managing pelvic floor dysfunction: Can weight loss reduce symptoms of pelvic floor

  42. What is the clinical and cost effectiveness of carbamazepine as initial treatment for trigeminal neuralgia compared with other pharmacological treatments?

    Recommendation ID CG173/3 Question What is the clinical and cost effectiveness of carbamazepine as initial treatment for trigeminal neuralgia