Intrabeam radiotherapy system for treating early breast cancer
Status In progress
Anticipated publication date TBC
Process MTA
Topic area
  • Cancer
  • Therapeutic procedures

Provisional Schedule

Closing date for invited submissions / evidence submission: 6 January 2014
1st appraisal committee meeting: 24 June 2014
2nd appraisal committee meeting: 27 August 2014
3rd appraisal committee meeting: 26 August 2015

Project Team

Project lead Bijal Joshi


Key events during the development of the guidance

Date Update
06 November 2015 The Committee decided that further work by the Institute would be required before it could issue a recommendation to the NHS. The Committee appreciated the advantages of Intrabeam, especially for people who are keen to avoid having external beam radiotherapy, but was also concerned about the remaining uncertainties in the evidence, and the difficulties these present for both patients and clinicians in making an informed choice about the best treatment. The technology appraisals team is exploring options for evidence development that could be used to support the use of Intrabeam intraoperative radiotherapy in the NHS. Consequently the timeline for the development of the provisional guidance has been extended.
September 2014 Following its discussion of Intrabeam radiotherapy for treating early breast cancer on 27th August, the Appraisal Committee wishes to request further information from the TARGIT-A clinical trial investigators. Please refer to the document Breast cancer (early) - intrabeam radiotherapy system: Request for further information, under project documents

For further information on how we develop guidance, please see or page about NICE technology appraisal guidance