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Topic prioritisation
Title
Prioritisation programme
Decision
Decision date
Dabrafenib with trametinib for adjuvant treatment of resected BRAF V600 mutation-positive melanoma
in
people aged 12 to 17 [TSID11839]
Medicines evaluation
Not selected
10 March 2026
Dronabinol for treating muscle spasticity
in
multiple sclerosis after 2 treatments [TSID10638]
Medicines evaluation
Not selected
11 February 2026
Dabrafenib for treating unresectable or metastatic BRAF V600 mutation positive melanoma
in
people 12 to 17 years [TSID12399]
Medicines evaluation
Not selected
4 February 2026
Dabrafenib with trametinib for treating unresectable or metastatic BRAF V600 mutation positive melanoma
in
people 12 to 17 years [TSID12398]
Medicines evaluation
Not selected
4 February 2026
Ponatinib for treating recurrent or refractory chronic myeloid leukaemia
in
people 1 to 17 years when another tyrosine kinase inhibitor is unsuitable [TSID12041]
Medicines evaluation
Not selected
29 January 2026
Vedolizumab for treating moderately to severely active Crohn's disease
in
people 2 to 17 years [TSID12312]
Medicines evaluation
Not selected
29 January 2026
Isavuconazol for treating invasive aspergillosis or mucormycosis
in
people 1 to 17 years [TSID12284]
Medicines evaluation
Not selected
29 January 2026
SEEG-guided radiofrequency thermocoagulation
in
refractory epilepsy
Interventional procedures
Awaiting decision
22 December 2025
Xeomin (botulinum neurotoxin type A) for treating lower or upper limb spasticity
in
people 2 to 17 years [TSID12297]
None selected
Not selected
20 November 2025
Lanadelumab for preventing recurrent attacks of hereditary angioedema
in
people 2 years and over [TSID12298]
None selected
Not selected
3 November 2025
Ivacaftor–tezacaftor–elaxcaftor and ivacaftor for treating cystic fibrosis with at least 1 F508del mutation
in
the CFTR gene
in
people 1 to under 2 years [TSID12295]
None selected
Not selected
3 November 2025
Vanzacaftor–tezacaftor–deutivacaftor for treating cystic fibrosis with 1 or more responsive mutations
in
the CFTR gene
in
people 2 to 5 years [TSID12296]
None selected
Not selected
3 November 2025
Mercaptamine hydrochloride for treating corneal cystine crystal deposits
in
people 6 months to under 2 years with cystinosis [TSID12261]
None selected
Not selected
9 October 2025
Semaglutide for treating type 2 diabetes
in
people 10 to 17 years [TSID12249]
None selected
Not selected
15 September 2025
Modified release hydrocortisone capsules for treating adrenal insufficiency
in
people 12 years and over [TSID12254]
None selected
Not selected
15 September 2025
Dasiglucagon for treating severe hypoglycaemia caused by type 1 diabetes
in
people under 6 years [TSID12255]
None selected
Not selected
15 September 2025
Dermal allograft augmentation
in
proximal humerus fracture fixation
None selected
Awaiting decision
2 September 2025
Ferric citrate for managing iron and serum phosphorus levels
in
anaemia associated with chronic kidney disease [TSID12221]
None selected
Not selected
4 August 2025
Oral cabotegravir with rilpivirine for treating HIV-1
in
people 12 to 17 years [TSID12214]
None selected
Not selected
16 June 2025
Long-acting injections of cabotegravir with rilpivirine for treating HIV-1
in
people 12 to 17 years [TSID12219]
None selected
Not selected
16 June 2025
Lutetium (177Lu) oxodotreotide for treating SSTR-positive advanced or inoperable gastroenteropancreatic neuroendocrine tumours
in
people 12 to 17 years [TSID12154]
None selected
Not selected
16 June 2025
Risankizumab for treating moderate to severe plaque psoriasis
in
people 6 to 17 years [TSID12204]
None selected
Not selected
16 June 2025
Leniolisib for untreated activated phosphoinositide 3-kinase delta syndrome
in
children 4 to 11 years [TSID12190]
None selected
Not selected
16 June 2025
Subcutaneous nivolumab–relatlimab for untreated unresectable or metastatic melanoma
in
people 12 years and over [TSID 12178]
None selected
Not selected
16 May 2025
Sulthiame for treating self-limiting epilepsy with centrotemporal spikes
in
children TSID 12106
None selected
Not selected
30 April 2025
Apremilast for treating juvenile psoriatic arthritis
in
people 5 to 17 years [TSID12089]
None selected
Not selected
10 April 2025
Doravirine–islatravir for treating HIV-1
in
people with virological suppression on antiretroviral therapy [TSID12173]
None selected
Not selected
10 April 2025
Ocrelizumab for treating relapsing–remitting multiple sclerosis
in
people 10 to 17 years [TSID12164]
None selected
Not selected
10 April 2025
Doravirine–islatravir for treating HIV-1
in
people with virological suppression on bictegravir, emtricitabine and tenofovir alafenamide combination treatment [TSID12171]
None selected
Not selected
4 April 2025
NEMOST growing domino for Neuromuscular early onset scoliosis with Risser 0
in
first surgical intention
HealthTech
Awaiting decision
19 March 2025
Veverimer for treating metabolic acidosis
in
chronic kidney disease [ID3832]
None selected
Awaiting decision
14 March 2025
Linaclotide acetate for treating functional constipation
in
people 6 to 17 years [TSID12125]
None selected
Not selected
5 March 2025
Vedolizumab for treating moderately to severely active ulcerative colitis
in
people 2 to 17 years [TSID12134]
None selected
Not selected
5 March 2025
High resolution anoscopy and laser therapy for intraepithelial neoplasia of the anus
in
high risk or immunocompromised patients
None selected
Awaiting decision
5 February 2025
Clindamycin for treating bacterial vaginosis
in
females aged 12 and older [TSID 12127]
None selected
Not selected
4 February 2025
Ustekinumab for treating moderately to severely active ulcerative colitis
in
children aged 2 to 17 years [TSID 12128]
None selected
Not selected
4 February 2025
Berotralstat for preventing recurrent attacks of hereditary angioedema
in
children aged 2 to 12 years [TSID 12132]
None selected
Not selected
4 February 2025
Lebrikizumab for treating atopic dermatitis
in
children [TSID12133]
None selected
Not selected
4 February 2025
Lebrikizumab for treating atopic dermatitis
in
children [TSID 12133_TSID 12135]
None selected
Not selected
4 February 2025
Avatrombopag for treating primary chronic immune thrombocytopenia
in
people 1 to 17 years [TSID12109]
None selected
Not selected
17 December 2024
NVK-002 for treating myopia
in
people 3 to 17 years [TSID11961]
None selected
Not selected
12 December 2024
Pitolisant for treating narcolepsy
in
children and young people 6 to 17 years ID6353
None selected
Not selected
9 December 2024
Entrectinib for treating NTRK fusion-positive solid tumours
in
people 1 month to 11 years [TSID12116]
None selected
Not selected
14 November 2024
Selumetinib granules for treating symptomatic and inoperable plexiform neurofibromas associated with type 1 neurofibromatosis
in
children 1 to 6 years [TSID12092]
None selected
Not selected
14 November 2024
Evinacumab for treating homozygous familial hypercholesterolemia
in
children aged 6 months to 11 [TSID11806]
None selected
Not selected
1 November 2024
Lomitapide for treating homozygous familial hypercholesterolaemia
in
people 5 to 17 years [TSID 12085]
None selected
Not selected
24 October 2024
Ustekinumab for the treatment of moderately to severely active Crohn's disease
in
children [TS ID 11955]
None selected
n/a
10 September 2024
Mexiletine hydrochloride for treating myotonia
in
children and adolescents with myotonic disorders [TS ID 11978]
None selected
Not selected
10 September 2024
Human normal immunoglobulin for preventing infection
in
chronic lymphocytic leukaemia [TSID12043]
None selected
Not selected
10 September 2024
Budesonide–glycopyrronium–formoterol fumarate for treating severe asthma
in
people 12 years and over TS ID 12018
None selected
Not selected
12 August 2024
Ferric maltol for treating iron deficiency anaemia
in
children and adolescents aged 1 month to 17 years TS ID 11994
None selected
Not selected
19 July 2024
Human immunoglobulin with recombinant human hyaluronidase for maintenance treatment of multifocal motor neuropathy
in
people of any age TSID 12033
None selected
Not selected
15 July 2024
Aflibercept for untreated retinopathy
in
babies born preterm TS ID 11943
None selected
Not selected
11 July 2024
Human normal immunoglobulin for preventing infection
in
chronic lymphocytic leukaemia [TSID12043]
None selected
Not selected
21 June 2024
Letermovir for preventing cytomegalovirus infection
in
people under 18 years after allogeneic haematopoietic stem cell transplant [TS ID 11868]
None selected
Not selected
28 May 2024
Olorofim for treating invasive fungal infections
in
people 16 years and over [TSID11983]
None selected
Not selected
18 April 2024
Vonicog alfa for preventing haemorrhage
in
people with von Willebrand disease when desmopressin is ineffective or not suitable [ID6272]
None selected
Not selected
4 April 2024
Guselkumab for treating chronic plaque psoriasis
in
children aged 6 to 17 years [TSID12002]
Medicines evaluation
Not selected
26 March 2024
MT547 QuickChange Incontinence Wrap for urinary incontinence
in
men (MIB237)
None selected
Not selected
7 January 2024
Golimumab for treating moderately to severely active ulcerative colitis
in
people aged 2 to 17 years [TSID11959]
None selected
Not selected
22 December 2023
RenalGuard Therapy for reduction
in
the incidence of Contrast-Associated AKI (CA-AKI)
in
at-risk patients
None selected
Not selected
30 November 2023
Transcatheter valve-
in
-valve implantation for the treatment of Tricuspid valve
None selected
Awaiting decision
26 October 2023
Apremilast for treating moderate to severe plaque psoriasis
in
people aged 6 to 17 [TSID11921]
None selected
Not selected
27 September 2023
Ivacaftor for treating cystic fibrosis with mutations
in
the CFTR gene
in
babies and children aged 1 to 3 months or weighing 3 kg to 24 kg [TSID11894]
None selected
Not selected
12 September 2023
TAK-880 for managing primary immunodeficiency diseases
in
people hypersensitive to IgA [TSID11883]
None selected
Not selected
12 September 2023
Spineform Hemibridge endoscopic vertebral stapling to reduce curvature
in
the growing scoliotic spine
in
children
None selected
Not selected
4 September 2023
Cipaglucosidase alfa with miglustat for treating late-onset Pompe disease
in
people 12 to 17 years [TSID11887]
None selected
Not selected
30 August 2023
Dapsone for treating COVID 19
in
people 40 years and over with high-risk comorbidity and people 70 years and over [TSID11892]
None selected
Not selected
28 August 2023
Implantable Vagus Nerve Stimulator
in
Heart Failure
None selected
Not selected
9 August 2023
Subcutaneous C1-esterase inhibitor for preventing recurrent attacks of hereditary angioedema
in
people 12 years and over [TSID11891]
None selected
Not selected
7 August 2023
Use of a glue or sealant to achieve lung volume reduction
in
emphysema and lung cancer
None selected
Not selected
27 July 2023
BPMpathway for rehabilitation support
in
joint replacement surgery, (MIB319)
None selected
Not selected
5 July 2023
Avtozma (tocilizumab biosimilar) for treating moderate to severe rheumatoid arthritis
in
people aged 18 to 75 [TSID11848]
None selected
Not selected
25 April 2023
Selective internal radiation therapy for unresectable colorectal metastases
in
the liver
None selected
Not selected
24 April 2023
Setmelanotide for treating obesity caused by a rare genetic disorder
in
children aged 2 to 5 [TSID11827]
None selected
Not selected
21 April 2023
Elexacaftor–tezacaftor–ivacaftor and ivacaftor for treating cystic fibrosis with at least 1 F508del mutation
in
the CFTR gene
in
children aged 2 to 5 [TSID10767]
None selected
Not selected
6 April 2023
Coronary venous arterialisation
in
patients with refractory angina
None selected
Not selected
30 March 2023
PromarkerD for predicting the risk of diabetic kidney disease
in
people with type 2 diabetes, (MT740)
None selected
Not selected
1 March 2023
Intravenous infusion of mesenchymal stromal cells
in
patients with severe recalcitrant psoriasis
None selected
Not selected
24 February 2023
Intravenous infusion of mesenchymal stromal cells
in
patients with severe recalcitrant psoriasis
None selected
Not selected
23 February 2023
Emicizumab for preventing bleeding episodes
in
people with mild or moderate haemophilia A [ID5098]
None selected
Not selected
16 February 2023
Baricitinib for treating moderate to severe atopic dermatitis
in
children and young people aged 2 to 17 [TSID10639]
None selected
Not selected
14 February 2023
Ceftobiprole medocaril for treating community- or hospital-acquired pneumonia
in
people 3 months to 17 years [TSID11819]
None selected
Not selected
9 February 2023
Subcutaneous belimumab for treating systemic lupus erythematosus
in
children aged 5 to 17 [TSID11828]
None selected
Not selected
7 February 2023
Bardoxolone methyl for treating chronic kidney disease
in
people 12 years and over with Alport syndrome [TSID9998]
None selected
Not selected
23 January 2023
Glucarpidase for reducing toxic plasma methotrexate levels
in
people aged 28 days and over [TSID10761]
None selected
Not selected
9 December 2022
Sacubitril valsartan for treating chronic heart failure with reduced ejection fraction
in
people under 18 years [TSID10350]
None selected
Not selected
6 December 2022
Macitentan for treating pulmonary arterial hypertension
in
people 1 month to 17 years [TSID11805]
None selected
Not selected
1 December 2022
DV7103 for treating cystinuria
in
people 6 months and over [TSID10438]
None selected
Further information required
18 November 2022
Teduglutide for treating short bowel syndrome
in
babies 4 to 12 months [TSID10755]
None selected
Not selected
26 October 2022
Crizanlizumab for preventing recurrent vaso-occlusive crises
in
sickle cell disease
in
young people aged 12 to 17 [TSID10766]
None selected
Not selected
10 October 2022
Hyaluronic acid injection
in
periprosthetic leakage / pharyngocutaneous fistula
in
patients with voice prosthesis
in
post-laryngectomy patients
None selected
Not selected
1 September 2022
Dimethyl fumarate for treating relapsing-remitting multiple sclerosis
in
people aged 13 to 17 [TSID11778]
None selected
Not selected
31 August 2022
Trans-septal transcatheter mitral valve-
in
-valve implantation for failed surgical mitral valve bioprosthesis
None selected
Further information required
1 July 2022
Dulaglutide for treating type 2 diabetes
in
children and young people [TSID10660]
None selected
Not selected
25 May 2022
TUC Safety Valve to prevent balloon inflation
in
the urethra during transurethral catheterisation (MT512)
None selected
Not selected
30 March 2022
TUC Safety Valve to prevent balloon inflation
in
the urethra during transurethral catheterisation (MT512)
None selected
Not selected
30 March 2022
d-NAV for optimization of personal insulin management
in
adults with type 2 diabetes (MT696)
None selected
Not selected
4 March 2022
Crizotinib for treating ALK-positive anaplastic large cell lymphoma or inflammatory myofibroblastic tumour
in
people 6 to 17 years [TSID10574]
None selected
Not selected
10 February 2022
Dupilumab for maintenance treatment of uncontrolled moderate to severe asthma
in
children 6 to 11 years [TSID10085]
None selected
Not selected
17 January 2022
CADScor system for ruling out coronary artery disease
in
people with symptoms of stable coronary artery disease (MT434
None selected
Not selected
28 October 2021
CADScor system for ruling out coronary artery disease
in
people with symptoms of stable coronary artery disease (MT434
None selected
Not selected
28 October 2021
MMprofiler for prognostic risk classification
in
multiple myeloma (MT623) (MIB270)
None selected
Not selected
25 August 2021
AI
in
retinal scanning MT524 (MIB265)
None selected
Not selected
22 July 2021
Moor LDLS-BI for assessing burn depth and healing potential
in
children and adults
None selected
Not selected
6 May 2021
Cor-Knot for tying suture knots
in
valve surgery
None selected
Not selected
1 July 2020
TUC Safety Valve to prevent balloon inflation
in
the urethra during transurethral catheterisation
None selected
Not selected
1 July 2020
Cytokine adsorption technologies for treating respiratory failure
in
people with COVID 19
None selected
Not selected
1 July 2020
Single-incision short sling mesh insertion for stress urinary incontinence
in
women
None selected
Further information required
2 April 2020
Fingolimod for treating relapsing multiple sclerosis
in
children and young people [ID1378]
None selected
Not selected
20 September 2018
Cervical ripening ballon for the induction of labour
in
women who have previously undergone cesarean section
None selected
Not selected
19 December 2013
TVB-009 (denosumab biosimilar) for treating postmenopausal osteoporosis
in
people aged 60 to 90 [TSID11807]
None selected
Not selected
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