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This guideline has been updated and replaced by NICE guideline NG212.
This guideline has been updated and replaced by the NICE guideline on tobacco: preventing uptake, promoting quitting and treating dependence (NG209).
After consultation the guidance has been withdrawn because it is no longer relevant to clinical practice. Rituximab is now routinely used outside its licensed indication. See NICE’s guideline on non-Hodgkin’s lymphoma.
This guidance has been updated and replaced by NICE technology appraisal guidance 887.
This guidance has been updated and replaced by NICE technology appraisal guidance 939.
This guidance has been updated and replaced by NICE technology appraisal guidance 477.
Immunosuppressive therapy for renal transplantation in adults (TA85)
This guidance has been updated and replaced by NICE technology appraisal guidance 481.
This guidance has been withdrawn.
Clopidogrel in the treatment of non-ST-segment-elevation acute coronary syndrome (TA80)
This guidance has been replaced by recommendations 1.3.4 to 1.3.8 in NICE guideline CG94 and by recommendation 1.3.18 in NICE guideline CG172.
The clinical effectiveness and cost effectiveness of new drugs for bipolar disorder (TA66)
This guidance has been updated and replaced NICE guideline CG38.
Guidance on the use of photodynamic therapy for age-related macular degeneration (TA68)
This guidance has been updated and replaced by NICE guideline NG82.
This guidance has been updated and replaced by NICE guideline CG66 [partially updated by NICE guideline CG87]).
This guidance has been updated and replaced by NICE technology appraisal guidance 764.
This guidance has been updated and replaced by NICE technology appraisal guidance 687.
This guidance has been replaced by NICE technology appraisal guidance 30 [Replaced by NICE guideline CG81].
Guidance on the use of patient-education models for diabetes (TA60)
This guidance has been replaced by NICE guideline NG17.
This guidance has been updated and replaced by NICE technology appraisal guidance 770.
Bezlotoxumab for preventing recurrent Clostridium difficile infection (terminated appraisal) (TA601)
This guidance has been updated and replaced by NICE guideline NG199.
The clinical effectiveness and cost effectiveness of anakinra for rheumatoid arthritis (TA72)
This appraisal has been updated and replaced by NICE guideline CG79.
Fostamatinib for treating refractory chronic immune thrombocytopenia (TA759)
This guidance has been updated and replaced by NICE technology appraisal guidance 835.
This guideline has been updated and replaced by NICE guideline CG137.
Crizanlizumab for preventing sickle cell crises in sickle cell disease (TA743)
NICE has withdrawn this guidance. Novartis will stop marketing crizanlizumab (Adakveo) because its marketing authorisation has been withdrawn by the Medicines and Healthcare products Regulatory Agency (MHRA). Novartis has issued a direct letter to healthcare professionals specialising in haematology. No new people will start taking crizanlizumab in the UK. Healthcare professionals should discuss alternative treatment options with people currently having crizanlizumab.
This guidance has been updated and replaced by NICE technology appraisal guidance 389.
Colorectal cancer (advanced) - irinotecan, oxaliplatin and raltitrexed (TA93)
This guidance has been updated and replaced by NICE guideline NG151. The recommendations on raltitrexed have been withdrawn because its use is established clinical practice.
This guidance has been replaced by NICE technology appraisal guidance 63.
Clopidogrel and modified-release dipyridamole in the prevention of occlusive vascular events (TA90)
This guideline has been updated and replaced by NICE technology appraisal 210.
Immunosuppressive therapy for renal transplantation in children and adolescents (TA99)
This guidance has been updated and replaced by NICE technology appraisal guidance 482.
This guidance has been updated and replaced by NICE guideline CG181.
This guidance has been updated and replaced by NICE technology appraisal guidance 852.
This guidance has been updated and replaced NICE technology appraisal guidance 158.
The clinical and cost effectiveness of proton pump inhibitors for the treatment of dyspepsia (TA7)
This guidance has been replaced by NICE guideline CG17. [Replaced by NICE guideline CG184]
This guidance has been updated and replaced by NICE technology appraisal guidance 816.
Guselkumab for treating active psoriatic arthritis after inadequate response to DMARDs (TA711)
This guidance has been updated and replaced by NICE technology appraisal guidance TA815.
Teduglutide for treating short bowel syndrome (terminated appraisal) (TA690)
This guidance has been updated and replaced by NICE technology appraisal guidance TA804.
This guidance has been updated and replaced by NICE technology appraisal guidance 946.
This guidance has been updated and replaced by NICE technology appraisal guidance 836.
This guidance has been updated and replaced by NICE technology appraisal guidance 908.
Osimertinib for untreated EGFR mutation-positive non-small-cell lung cancer (TA621)
This technology appraisal guidance has been updated and replaced by NICE technology appraisal guidance 654
This guideline has been updated and replaced by NICE guideline CG137.
Implantable cardioverter defibrillators for arrhythmias (TA95)
This guidance has been updated and replaced by NICE technology appraisal guidance 314.
Computerised cognitive behaviour therapy for depression and anxiety (TA97)
The guidance was withdrawn in July 2018 to allow OCFighter to be considered for an improving access to psychological therapies assessment briefing. If OCFighter is not selected, it may be considered for a medtech innovation briefing.
This guidance has been updated and replaced by NICE guideline NG87.
This guidance has been updated and replaced by NICE technology appraisal guidance 908.
Radium-223 dichloride for treating hormone-relapsed prostate cancer with bone metastases (TA376)
This guidance has been updated and replaced by NICE technology appraisal guidance 412.
This guidance has been updated and replaced by NICE guideline PH10.
Apremilast for treating moderate to severe plaque psoriasis (TA368)
This guidance has been updated and replaced by NICE technology appraisal guidance 419. The clinical effectiveness and cost effectiveness of rituximab for follicular lymphoma (TA37)
This guidance has been updated and replaced by NICE technology appraisal guidance 137.
This guidance has been updated and replaced by NICE technology appraisal guidance 476.