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Guidance programme

Advice programme

Showing 2551 to 2600 of 2990 results for all

  1. Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine assessment and monitoring of changes in pulmonary status in people with cystic fibrosis?

    Assessing the severity of lung disease is difficult in younger children. Not all children under 5 years can do spirometry tests and they...

  2. Key question: effective

    This resource is intended to demonstrate how our guidance can be used in the Care Quality Commission (CQC) assessment process.

  3. What type of training and awareness-raising can improve how health and social care practitioners: - promote vitamin D supplements among at-risk groups - improve the local population's awareness of, and attitudes towards, vitamin D supplements - uptake of vitamin D supplements?

    adherence or any unintentional consequences. The recommendations apply to all at-risk groups, but there is a particular need for...

  4. What is the effectiveness and safety of extended pharmacological venous thromboembolism (VTE) prophylaxis for people who have been discharged after treatment for COVID-19?

    extended pharmacological VTE prophylaxis O:• incidence of VTE• mortality (all-cause, inpatient, COVID-19 related)• serious adverse...

  5. Home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome (HTG735)

    Evidence-based recommendations on home-testing devices for diagnosing obstructive sleep apnoea hypopnoea syndrome.

  6. Epilepsy syndromes: What are the initial and add-on AEDs of choice in the treatment of the epilepsy syndromes with onset in childhood, for example, myoclonic-astatic epilepsy and Dravet syndrome?

    attempt to obtain data on pharmaco-resistance the possibility of including all children with specific epilepsy syndromes for...

  7. Prevalence of risk factors for falling in older inpatients:- Which risk factors for falling that can be treated, improved or managed during the hospital stay are most prevalent in older patients who fall in inpatient settings in the UK?

    risk factors for falling in the inpatient setting, but these studies are not all relevant to a current UK hospital population....

  8. What is the effectiveness of statin therapy in older people?

    older than 80 years yet the important effect of age on CVD risk suggests that all people in this group should be offered statin therapy....

  9. Effectiveness of the progestogen-only pill, injectable progestogens, or progestogen implants in alleviating HMB:- How effective are the progestogen-only pill, injectable progestogens or progestogen implants in alleviating HMB?

    first-line pharmacological treatment for HMB, but it is not acceptable to all women. Combined oral contraceptives have also been shown...

  10. HPV testing:- What is the comparative effectiveness of single-step laboratory diagnostic tests to identify human papillomavirus (HPV) against current diagnostic test algorithms and reference standards in people with cancer of the oropharynx?

    implication. Current methods use a 2-step procedure that is not widely available in all treatment centres. A single-step test is likely...

  11. Alpha-Stim AID for anxiety disorders (HTG570)

    Evidence-based recommendations on Alpha-Stim AID for managing anxiety disorders.

  12. Transjugular intrahepatic portosystemic shunt:- What is the quality of life in people who have had a transjugular intrahepatic portosystemic shunt (TIPS)?

    veins in the stomach, oesophagus or intestines, ascites or hydrothorax – all of which will have had a detrimental effect on their...

  13. Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first variceal bleeds in people with cirrhosis that is associated with small oesophageal varices?

    half of patients with cirrhosis have oesophageal varices, and one-third of all patients with varices will experience bleeding at some...

  14. Treosulfan with fludarabine for malignant disease before allogeneic stem cell transplant (TA640)

    Evidence-based recommendations on treosulfan (Trecondi) with fludarabine for conditioning treatment before allogeneic haematopoietic stem cell transplant for malignant diseases in people for whom a reduced intensity regimen would be suitable.

  15. Dapagliflozin in triple therapy for treating type 2 diabetes (TA418)

    Evidence-based recommendations on dapagliflozin (Forxiga) given with 2 other drugs for treating type 2 diabetes in adults.

  16. Upadacitinib for treating active ankylosing spondylitis (TA829)

    Evidence-based recommendations on upadacitinib (Rinvoq) for treating active ankylosing spondylitis that is not controlled well enough with conventional therapy in adults.

  17. Constipation in children and young people (QS62)

    This quality standard covers the diagnosis and management of constipation of unknown cause in babies, children and young people (from birth to 18 years). It describes high-quality care in priority areas for improvement.

  18. Irritable bowel syndrome in adults (QS114)

    This quality standard covers diagnosing and managing irritable bowel syndrome in adults. It describes high-quality care in priority areas for improvement.

  19. Bladder EpiCheck for detecting bladder cancer recurrence (MIB293)

    NICE has developed a medtech innovation briefing (MIB) on Bladder EpiCheck for detecting bladder cancer recurrence .

  20. Does early review of service provision and referral to additional specialist palliative care services improve outcomes for adults with progressive non-cancer disease thought to be approaching the end of their life?

    patients are typically referred very late to specialist palliative care, if at all. Further research would compare outcomes for people...

  21. Current evidence on the safety and efficacy of electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease (GORD) is limited in quantity and quality. Therefore, this procedure should only be used in the context of research.

    for surgical treatment for GORD in the longer term (at least 2 years) and all complications should be reported. NICE may update the...

  22. Repositioning:- When repositioning a person who is at risk of developing a pressure ulcer, what is the most effective position – and optimum frequency of repositioning – to prevent a pressure ulcer developing?

    evidence on the most efficient position and frequency of repositioning for all age groups. Many studies include people who are on...

  23. Probiotic and prebiotic supplements:- What is the clinical and cost effectiveness of probiotics or prebiotics to treat NAFLD in adults, young people and children?

    the most common metabolic liver disease, occurring in approximately 30% of all adults, around 46% of obese people and around 53% of...

  24. Reasons for refusal for consent:- Why do families refuse to give permission for organ donation?

    The study could be, for example, a multi-centre observational study where all family members (those that did and those that did not give...

  25. Support for black and minority ethnic groups:- How effective and cost effective are different approaches to supporting people from black and minority ethnic groups using intermediate care?

    planning and delivering intermediate care for minority groups. This includes all 4 service models of intermediate care. Qualitative data...

  26. Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate for community staff, including dementia-specific elements on managing anxiety, communication, nutritional status and personal care?

    However, it is not clear if it is effective to provide basic training to all staff who come into contact with people living with...

  27. What is the effectiveness and safety of standard-dose compared with intermediate-dose pharmacological venous thromboembolism (VTE) prophylaxis for people with COVID-19, with or without additional risk factors for VTE?

    anticoagulants vitamin K antagonists antiplatelets O:• incidence of VTE• mortality (all-cause, inpatient, COVID-19 related)• admission...

  28. Medication for promoting de-escalation:- Which medication is effective in promoting de-escalation in people who are identified as likely to demonstrate significant  violence?

    degree of sedation, acceptability of the medication and adverse effects, all recorded over a suitable timescale to match the...

  29. Psychological assessment:- What is the most effective measure of psychological functioning to use as a test for thresholds of concern in people with cystic fibrosis?

    most cost-effective service that can be provided. To prevent mental health problems, all people withcystic fibrosis would need to have...

  30. In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based use of rapid nucleic acid amplification tests?

    with a possible diagnosis of TB. There is a trade-offbetween ensuring that all people with active TB are diagnosed and avoiding a large...

  31. Quantitative faecal immunochemical testing to guide colorectal cancer pathway referral in primary care (HTG690)

    Evidence-based recommendations on quantitative faecal immunochemical testing to guide colorectal cancer pathway referral in primary care.

  32. What is the most effective technological solution for minimising wrong implant selection during joint replacement surgery?

    other activity and formally inspect each implant component, would ensure that all components are compatible. The second stop moment...

  33. Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary, can radiotherapy target volumes be selected based on clinical and pathological factors?

    clinical teams will treat the neck disease alone and others will treat some or all potential primary sites with the radiotherapy with or...

  34. Dostarlimab for previously treated advanced or recurrent endometrial cancer with high microsatellite instability or mismatch repair deficiency (TA779)

    Evidence-based recommendations on dostarlimab (Jemperli) for treating advanced or recurrent endometrial cancer with high microsatellite instability or mismatch repair deficiency in adults who have had platinum-based chemotherapy.

  35. What are the appropriate indications, effectiveness and safety of LDL apheresis in people with heterozygous FH?

    antisense oligonucleotides (ApoB). A national register should be established for all people with FH who are referred for and/or are...

  36. Use of technology in providing care- What are the views and experiences of people who use adult social care services on assistive technologies?

    example, integrated systems of sensors, alarms and remote monitoring. Across all population groups, there is a paucity of evidence about...

  37. LIVERFASt for assessing and monitoring liver fibrosis, activity and steatosis (MIB317)

    NICE has developed a medtech innovation briefing (MIB) on LIVERFASt for assessing and monitoring liver fibrosis, activity and steatosis .

  38. Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis (TA199)

    Evidence-based recommendations on etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira) for treating active and progressive psoriatic arthritis in adults.

  39. Schizophrenia: omega-3 fatty acid medicines (ESUOM19)

    Summary of the evidence on omega-3 fatty acid medicines for treating schizophrenia to inform local NHS planning and decision-making

  40. Assessment tools for health promotion:- What are the most effective tools to determine the health promotion needs of people in prison?

    difficulties in accessing exercise programmes or information on sexual health. All of these may exacerbate existing health conditions or...

  41. Endocuff Vision for assisting visualisation during colonoscopy (HTG514)

    Evidence-based recommendations on Endocuff Vision for assisting visualisation during colonoscopy.

  42. Renal and ureteric stones (QS195)

    This quality standard covers assessing and managing renal and ureteric stones in children, young people and adults. It describes high-quality care in priority areas for improvement.

  43. Acute heart failure (QS103)

    This quality standard covers the care of adults (aged 18 and over) with suspected or confirmed acute heart failure. It describes high-quality care in priority areas for improvement.

  44. Food allergy (QS118)

    This quality standard covers diagnosing, assessing and managing food allergy in children and young people (under 19) and adults. It describes high-quality care in priority areas for improvement.

  45. Psoriasis (QS40)

    This quality standard covers assessing and managing psoriasis in adults, young people and children. It describes high-quality care in priority areas for improvement.