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Guidance programme

Advice programme

Showing 2551 to 2600 of 3030 results for all

  1. What is the effectiveness of statin therapy in older people?

    older than 80 years yet the important effect of age on CVD risk suggests that all people in this group should be offered statin therapy....

  2. Effectiveness of the progestogen-only pill, injectable progestogens, or progestogen implants in alleviating HMB:- How effective are the progestogen-only pill, injectable progestogens or progestogen implants in alleviating HMB?

    first-line pharmacological treatment for HMB, but it is not acceptable to all women. Combined oral contraceptives have also been shown...

  3. HPV testing:- What is the comparative effectiveness of single-step laboratory diagnostic tests to identify human papillomavirus (HPV) against current diagnostic test algorithms and reference standards in people with cancer of the oropharynx?

    implication. Current methods use a 2-step procedure that is not widely available in all treatment centres. A single-step test is likely...

  4. Transjugular intrahepatic portosystemic shunt:- What is the quality of life in people who have had a transjugular intrahepatic portosystemic shunt (TIPS)?

    veins in the stomach, oesophagus or intestines, ascites or hydrothorax – all of which will have had a detrimental effect on their...

  5. Treating small oesophageal varices:- Do non-selective beta-blockers improve survival and prevent first variceal bleeds in people with cirrhosis that is associated with small oesophageal varices?

    half of patients with cirrhosis have oesophageal varices, and one-third of all patients with varices will experience bleeding at some...

  6. Bipolar disorder, psychosis and schizophrenia in children and young people (QS102)

    This quality standard covers recognition, early intervention and long-term management of bipolar disorder, psychosis and schizophrenia in children and young people (under 18). It also includes support for parents and carers. It describes high-quality care in priority areas for improvement.

  7. Acute respiratory infection in over 16s: initial assessment and management including virtual wards (hospital at home) (QS210)

    This quality standard covers the initial assessment and management of suspected acute respiratory infection in over 16s, including acute respiratory infection virtual wards.

  8. Does early review of service provision and referral to additional specialist palliative care services improve outcomes for adults with progressive non-cancer disease thought to be approaching the end of their life?

    patients are typically referred very late to specialist palliative care, if at all. Further research would compare outcomes for people...

  9. Current evidence on the safety and efficacy of electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux disease (GORD) is limited in quantity and quality. Therefore, this procedure should only be used in the context of research.

    for surgical treatment for GORD in the longer term (at least 2 years) and all complications should be reported. NICE may update the...

  10. Repositioning:- When repositioning a person who is at risk of developing a pressure ulcer, what is the most effective position – and optimum frequency of repositioning – to prevent a pressure ulcer developing?

    evidence on the most efficient position and frequency of repositioning for all age groups. Many studies include people who are on...

  11. Probiotic and prebiotic supplements:- What is the clinical and cost effectiveness of probiotics or prebiotics to treat NAFLD in adults, young people and children?

    the most common metabolic liver disease, occurring in approximately 30% of all adults, around 46% of obese people and around 53% of...

  12. Reasons for refusal for consent:- Why do families refuse to give permission for organ donation?

    The study could be, for example, a multi-centre observational study where all family members (those that did and those that did not give...

  13. Artificial intelligence (AI)-derived software to help clinical decision making in stroke (HTG708)

    Evidence-based recommendations on artificial intelligence-derived software to help clinical decision making in stroke.

  14. Support for black and minority ethnic groups:- How effective and cost effective are different approaches to supporting people from black and minority ethnic groups using intermediate care?

    planning and delivering intermediate care for minority groups. This includes all 4 service models of intermediate care. Qualitative data...

  15. Staff training:- What is the cost effectiveness of using a dementia-specific addition to the Care Certificate for community staff, including dementia-specific elements on managing anxiety, communication, nutritional status and personal care?

    However, it is not clear if it is effective to provide basic training to all staff who come into contact with people living with...

  16. Faltering growth: recognition and management of faltering growth in children (NG75)

    This guideline covers recognition, assessment and monitoring of faltering growth in infants and children. It includes a definition of growth thresholds for concern and identifying the risk factors for, and possible causes of, faltering growth. It also covers interventions, when to refer, service design, and information and support.

  17. Cataracts in adults: management (NG77)

    This guideline covers managing cataracts in adults aged 18 and over. It aims to improve care before, during and after cataract surgery by optimising service organisation, referral and surgical management, and reducing complications. It further aims to improve the availability of information for people with cataracts before, during and after cataract surgery.

  18. Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and management (CG84)

    This guideline covers diagnosing, managing and referring infants and young children younger than 5 years who present with acute diarrhoea (lasting up to 14 days) with or without vomiting. It aims to improve the diagnosis and management of infective gastroenteritis and appropriate escalation of care.

  19. Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (HTG360)

    Evidence-based recommendations on the My5-FU assay for measuring levels of 5-flurouracil (5-FU) in patients having chemotherapy, to help guide changes to the dose of 5-FU.

  20. Minimally invasive video-assisted thyroidectomy (HTG349)

    Evidence-based recommendations on minimally invasive video-assisted thyroidectomy. This involves inserting instruments through a small cut (keyhole surgery) to remove part or all of the gland.

  21. Antimicrobial prescribing: delafloxacin for community-acquired pneumonia (ES37)

    Summary of the evidence on delafloxacin for community-acquired pneumonia in adults

  22. i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department (MIB38)

    NICE has developed a medtech innovation briefing (MIB) on i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department

  23. What is the effectiveness and safety of standard-dose compared with intermediate-dose pharmacological venous thromboembolism (VTE) prophylaxis for people with COVID-19, with or without additional risk factors for VTE?

    anticoagulants vitamin K antagonists antiplatelets O:• incidence of VTE• mortality (all-cause, inpatient, COVID-19 related)• admission...

  24. Medication for promoting de-escalation:- Which medication is effective in promoting de-escalation in people who are identified as likely to demonstrate significant  violence?

    degree of sedation, acceptability of the medication and adverse effects, all recorded over a suitable timescale to match the...

  25. Psychological assessment:- What is the most effective measure of psychological functioning to use as a test for thresholds of concern in people with cystic fibrosis?

    most cost-effective service that can be provided. To prevent mental health problems, all people withcystic fibrosis would need to have...

  26. In people with suspected TB, what is the relative clinical and cost effectiveness of universal andrisk-based use of rapid nucleic acid amplification tests?

    with a possible diagnosis of TB. There is a trade-offbetween ensuring that all people with active TB are diagnosed and avoiding a large...

  27. Laparoscopic gastric plication for the treatment of severe obesity (HTG293)

    Evidence-based recommendations on laparoscopic gastric plication for the treatment of morbid obesity. This involves folding the stomach in on itself and stitching it together to reduce its volume.

  28. Partial replacement of the meniscus of the knee using a biodegradable scaffold (HTG289)

    Evidence-based recommendations on partial replacement of the meniscus of the knee using a biodegradable scaffold. This involves placing a biodegradable implant into the meniscus to support regrowth and repair of the damage.

  29. Tegaderm CHG securement dressing for vascular access sites in critically ill adults (HTG379)

    Evidence-based recommendations on Tegaderm CHG securement dressing for vascular access sites in critically ill adults.

  30. Executive team

    Day-to-day decision making is the responsibility of NICE's executive team.

  31. What is the most effective technological solution for minimising wrong implant selection during joint replacement surgery?

    other activity and formally inspect each implant component, would ensure that all components are compatible. The second stop moment...

  32. Unknown primary of presumed upper aerodigestive tract origin:- In people with CUADT of unknown primary, can radiotherapy target volumes be selected based on clinical and pathological factors?

    clinical teams will treat the neck disease alone and others will treat some or all potential primary sites with the radiotherapy with or...

  33. PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection (MIB200)

    NICE has developed a medtech innovation briefing (MIB) on PIUR tUS for abdominal aortic aneurysm surveillance and endovascular aneurysm repair endoleak detection .

  34. Noctura 400 Sleep Mask for diabetic retinopathy and diabetic macular oedema (MIB144)

    NICE has developed a medtech innovation briefing (MIB) on Noctura 400 Sleep Mask for diabetic retinopathy and diabetic macular oedema .

  35. What are the appropriate indications, effectiveness and safety of LDL apheresis in people with heterozygous FH?

    antisense oligonucleotides (ApoB). A national register should be established for all people with FH who are referred for and/or are...

  36. Use of technology in providing care- What are the views and experiences of people who use adult social care services on assistive technologies?

    example, integrated systems of sensors, alarms and remote monitoring. Across all population groups, there is a paucity of evidence about...

  37. Lung cancer: Treatment pathways

    pathways (linked below), or grouped together in a single interactive PDF of all treatment pathways for squamous and non-squamous...

  38. Key question: effective

    This resource is intended to demonstrate how our guidance can be used in the Care Quality Commission (CQC) assessment process.

  39. Assessment tools for health promotion:- What are the most effective tools to determine the health promotion needs of people in prison?

    difficulties in accessing exercise programmes or information on sexual health. All of these may exacerbate existing health conditions or...

  40. Cannabidiol for treating seizures caused by tuberous sclerosis complex (TA873)

    Evidence-based recommendations on cannabidiol (Epidyolex) for treating seizures caused by tuberous sclerosis complex.

  41. Dupilumab for treating severe chronic rhinosinusitis with nasal polyps (TA1134)

    Evidence-based recommendations on dupilumab (Dupixent) for treating severe chronic rhinosinusitis with nasal polyps in adults.

  42. Epcoritamab for treating relapsed or refractory follicular lymphoma after 2 or more lines of systemic treatment (TA1139)

    Evidence-based recommendations on epcoritamab (Tepkinly) for treating relapsed or refractory follicular lymphoma after 2 or more lines of systemic treatment in adults.

  43. Rehabilitation: - What are the barriers to people with major trauma receiving early rehabilitation after rehabilitation assessment? What changes to services are needed to overcome these barriers?

    needs assessed, and that a rehabilitation prescription should be provided for all patients with rehabilitation needs. The rehabilitation...

  44. Pressure redistributing devices: Dopressure redistributing devices reduce the development of pressure ulcers for those who are at risk of developing a pressure ulcer?

    needed to identify what devices are beneficial for specific at-risk sites for all age groups. Source guidance details Comes from...