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This guide gives an overview of the process for developing evidence summaries. Evidence summaries provide advice but do not include recommendations and are not formal NICE guidance
assessment and decision modelling • the natural history and long-term course of treatment-resistant depression and health-related...
Evidence-based recommendations on the RD-100i OSNA system and Metasin test for detecting sentinel lymph node metastases in people having breast cancer surgery.
NICE has developed a medtech innovation briefing (MIB) on Smart Peak Flow for monitoring asthma .
Beta interferon and glatiramer acetate for the treatment of multiple sclerosis (TA32)
This guidance has been updated and replaced by NICE technology appraisal guidance 527.
Non-rigid stabilisation techniques for the treatment of low back pain (IPG183)
This guidance has been updated and replaced by NICE HealthTech guidance 239.
Non-rigid stabilisation techniques for the treatment of low back pain (IPG366)
Interventional procedures, IPG366 - Issued: November 2010 --> We have moved interventional procedures guidance 366 to become HealthTech guidance 239. This is to better reflect the NICE HealthTech programme which combines the former NICE Diagnostics Assessment programme, Interventional Procedures programme and Medical Technologies Evaluation programme and to help you find relevant content more quickly. The guidance itself has not changed.
Radiofrequency ablation for the treatment of colorectal metastases in the liver (IPG92)
This guidance has been updated and replaced by NICE HealthTech guidance 208.
agreed that hypothyroidism needs thyroid hormone replacement. Potential treatments are levothyroxine, usually prescribed to everyone,...
NICE is committed to supporting the national agenda for achieving a sustainable health and care system.
Living-donor lung transplantation for end-stage lung disease (HTG111)
Evidence-based recommendations on living-donor lung transplantation for end-stage lung disease. This involves removing a lung from each of the two donors and replacing the recipient's lungs with the donor lungs.
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Sections for HTG111
remains about the accuracy and consequent identification of appropriate treatment by paraprofessionals in primary care. An assessment by...
This guidance has been replaced by NICE technology appraisal guidance 98 [Replaced by NICE guideline NG87].
Bevacizumab for the first-line treatment of metastatic breast cancer (TA147)
This appraisal has been updated and replaced by NICE technology appraisal 214.
Cetuximab for the first-line treatment of metastatic colorectal cancer (TA176)
This guidance has been updated and replaced by NICE technology appraisal guidance 439.
Erlotinib for the treatment of non-small-cell lung cancer (TA162)
This guidance has been updated and replaced by NICE technology appraisal guidance 374.
PredictSURE IBD and IBDX to guide treatment of Crohn's disease (DG45)
We have moved Diagnostics guidance 45 to become HealthTech guidance 610. This is to better reflect the NICE HealthTech programme which combines the former NICE Diagnostics Assessment programme, Interventional Procedures programme and Medical Technologies Evaluation programme and to help you find relevant content more quickly. The guidance itself has not changed.
Ambulight PDT for the treatment of non-melanoma skin cancer (MTG6)
We have moved medical technologies guidance 6 to become HealthTech guidance 268. This is to better reflect the NICE HealthTech programme which combines the former NICE Diagnostics Assessment programme, Interventional Procedures programme and Medical Technologies Evaluation programme and to help you find relevant content more quickly. The guidance itself has not changed.
Human growth hormone for the treatment growth failure in children (TA42)
This guidance has been updated and replaced by NICE technology appraisal guidance 188.
Telaprevir for the treatment of genotype 1 chronic hepatitis C (TA252)
Telaprevir no longer has a marketing authorisation in the UK so this guidance has been withdrawn.
notes(if applicable) Why this is important:- Epidural injection of treatments, including corticosteroids, is commonly offered to people...
important:- There is a lack of published evidence on care pathways on treatment, management and follow-up of people with coexisting...
efficacy of the procedure. Therefore, laparoscopic gastric plication for the treatment of severe obesity should only be used with...
L-Dex U400 for lymphoedema after breast cancer treatment (MIB111)
April 2026: This Medtech innovation briefing has been withdrawn because the L-Dex U400 device is no longer available in the UK.
are still clinically and cost effective. Retaining more service users in treatment could further significantly improve outcomes for...
Percutaneous interlaminar endoscopic lumbar discectomy for sciatica (HTG411)
Evidence-based recommendations on percutaneous interlaminar endoscopic lumbar discectomy for sciatica in adults. This involves removing part of the damaged spinal disc to relieve the symptoms of sciatica.
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recognised, resulting in some people not being offered the most appropriate treatment. Research is needed to help healthcare...
concentration in treated children with FH receiving lipid-modifying drug therapy. Treatment is recommended from 10 years onwards,...
diagnosis for people who need enteral nutrition support during curative treatment. Variation across the UK exists as a result of...
is important:- Quality of life is the most important overall measure of treatment effect for patients as it measures their life...
impact of adenomyosis on symptoms of HMB or the best treatment for this condition. Optimising treatment can lead to better...
This guidance has been replaced by NICE technology appraisal guidance 317.
Computerised cognitive behaviour therapy (CCBT) for the treatment of depression and anxiety (TA51)
This guidance has been updated and replaced by NICE technology appraisal guidance 97.
Guidance on the use of gemcitabine for the treatment of pancreatic cancer (TA25)
This guidance has been replaced by NICE guideline NG85.
HealthVCF for detecting vertebral compression fractures on CT scans (MIB267)
NICE has developed a medtech innovation briefing (MIB) on HealthVCF for detecting vertebral compression fractures on CT scans .
at the end of this treatment period is important, since some people remain at high risk of fracture and require continued...
morbidity and mortality. As a result, NASH has been the main target for treatment in NAFLD. This is because reducing the severity of...
basis for needs assessment and decisions about therapeutic interventions, treatment placements and care plans.For those in the criminal...
How safe are drugs used to treat bipolar disorder in pregnancy and the postnatal period?
explanatory notes(if applicable) Drugs are effective for the acute treatment of bipolar disorder and for preventing relapse. All drugs...
diagnose non‑bladder injuries. People who do not have injuries needing urgent treatment may then either be given another CT scan or a...
Biographies and registered interests for members of the Technology Appraisal Committee A
Biographies and registered interests for members of the Technology Appraisal Committee A
Evidence-based recommendations on viscoelastometric point-of-care testing devices (the ROTEM, TEG and Sonoclot systems).
Cox-II inhibitors for the treatment of osteoarthritis and rheumatoid arthritis (TA27)
This guidance has been replaced by NICE guideline CG59 and NICE guideline CG79.
Laser in situ keratomileusis (LASIK) for the treatment of refractive errors (IPG102)
This guidance has been replaced by NICE interventional procedure guidance 164.
Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (TA111)
This guidance has been updated and replaced by NICE technology appraisal 217.
Eribulin for the treatment of locally advanced or metastatic breast cancer (TA250)
This guidance has been updated and replaced by NICE technology appraisal guidance 423 and NICE technology appraisal guidance 515.
Retigabine for the adjunctive treatment of partial onset seizures in epilepsy (TA232)
The guidance has been withdrawn because GlaxoSmithKline has discontinued retigabine (Trobalt) due to limited usage.
diagnose non-bladder injuries. People who do not have injuries needing urgent treatment may then either be given another CT scan or a...
endovascular treatment. Infra-geniculate disease is more complex to treat by endovascular means, and the risks and benefits of different...