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Showing 2901 to 2950 of 3765 results for treatment

  1. Neonatal parenteral nutrition (QS205)

    This quality standard covers parenteral nutrition (intravenous feeding) for babies born preterm, up to 28 days after their due birth date, and babies born at term, up to 28 days after their birth. It describes high-quality care in priority areas for improvement.

    Quality standard
    Published
    22 March 2022
    View quality statements

    Sections for QS205

  2. Maintaining the benefits of early intervention in psychosis services after discharge:- How can the benefits of early intervention in psychosis services be maintained once service users are discharged after 3 years?

    augmented (step-down) care in community mental health services versus treatment as usual to determine whether the gains of early...

    Research recommendation
    Published
    9 June 2015

  3. Additional maintenance therapy for asthma uncontrolled on a moderate dose of ICS plus LABA with or without LTRA:- What is the clinical and cost effectiveness of offering additional maintenance therapy to adults, young people and children with asthma that is uncontrolled on a moderate dose of ICS plus LABA with or without LTRA?

    LAMA is not cost effective compared with treatment with a placebo. In current practice, the alternative treatment options...

    Research recommendation
    Published
    18 October 2018

  4. Clinical trials should be conducted comparing ticagrelor with prasugrel in people with acute coronary syndromes (ACS).

    Source guidance details Comes from guidance Ticagrelor for the treatment of acute coronary syndromes Number TA236 Date issued

    Research recommendation
    Published
    9 June 2015

  5. Further research into whether ticagrelor is particularly beneficial in any clinical or biological subgroups would be useful.

    Source guidance details Comes from guidance Ticagrelor for the treatment of acute coronary syndromes Number TA236 Date issued

    Research recommendation
    Published
    9 June 2015

  6. Insertion of hydrogel keratoprosthesis (IPG69)

    Evidence-based recommendations on insertion of hydrogel keratoprosthesis. This involves putting an artificial cornea into place in a pocket made in the front part of the eye.

    Interventional procedures guidance
    Published
    23 June 2004
    View recommendations

    Sections for IPG69

  7. Does the use of barbed sutures for wound closure reduce the incidence of surgical site infection?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  8. Which closure method or technique is the most effective for reducing surgical site infections in patients undergoing emergency surgery?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  9. What is the contribution to clinical effectiveness of the timing of nasal decolonisation and body wash for the prevention of surgical site infection?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  10. What is the clinical effectiveness of preoperative nasal decolonisation using mupirocin in combination with a chlorhexidine body wash in the whole population?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    16 August 2019

  11. What is the effectiveness of decolonisation using alternative interventions in combination with nasal decolonisation in the prevention of surgical site infections when chlorhexidine is contraindicated?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  12. What is the clinical and cost effectiveness of a double application of antiseptic to the skin at the surgical site compared with a single application?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  13. What is the clinical and cost effectiveness of different modes of applying skin antiseptic before incision in the prevention of surgical site infection?

    Comes from guidance Surgical site infections: prevention and treatment Number NG125 Date issued April 2019 Other details

    Research recommendation
    Published
    26 October 2020

  14. Further studies on the clinical effectiveness of mifamurtide when combined with the chemotherapy typical of UK clinical practice would be useful to determine the size of the effect of mifamurtide.

    Source guidance details Comes from guidance Mifamurtide for the treatment of osteosarcoma Number TA235 Date issued October 2011

    Research recommendation
    Published
    9 June 2015

  15. Pregnancy and complex social factors: a model for service provision for pregnant women with complex social factors (CG110)

    This guideline covers antenatal care for all pregnant women with complex social factors (particularly alcohol or drug misuse, recent migrant or asylum seeker status, difficulty reading or speaking English, aged under 20, domestic abuse). It offers advice on improving access to care, maintaining contact with antenatal carers, and additional information and support for these women.

    Clinical guideline
    Published
    22 September 2010
    View recommendations

    Sections for CG110

  16. Endovascular closure of atrial septal defect (IPG96)

    Evidence-based recommendations on endovascular closure of atrial septal defect. This involves inserting a small blocking device into the heart, which is gently inflated to close the hole.

    Interventional procedures guidance
    Published
    27 October 2004
    View recommendations

    Sections for IPG96

  17. Research should be carried out to compare the clinical effectiveness of bendamustine with chlorambucil at the higher dose used in the Chronic Lymphocytic Leukaemia Trial 4 (CLL4).

    details Comes from guidance Bendamustine for the first-line treatment of chronic lymphocytic leukaemia Number TA216 Date issued

    Research recommendation
    Published
    9 June 2015

  18. Antibiotics for suspected early-onset infection: What is the incidence and severity of adverse effects with antibiotics used to prevent or treat early-onset neonatal infection?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  19. Olaparib for maintenance treatment of BRCA-negative platinum-sensitive relapsed ovarian, fallopian tube or primary peritoneal cancer [ID6205]

    Discontinued Reference number: GID-TA10965

    Technology appraisal guidance
    Discontinued

  20. FreeStyle Libre for glucose monitoring (MIB110)

    NICE has developed a medtech innovation briefing (MIB) on FreeStyle Libre for glucose monitoring .

    Medtech innovation briefing
    Last updated
    29 September 2017

  21. Studies exploring the effectiveness of bevacizumab in people previously treated with a taxane and its effects on health-related quality of life.

    guidance Bevacizumab in combination with capecitabine for the first-line treatment of metastatic breast cancer Number TA263 Date issued

    Research recommendation
    Published
    9 June 2015

  22. The effectiveness of pulsatile gonadotrophin-releasing hormone in women with clomifene citrate-resistant polycystic ovary syndrome is uncertain and is therefore not recommended outside a research context. [2004]

    details Comes from guidance Fertility problems: assessment and treatment Number CG156 Date issued February 2013 Other

    Research recommendation
    Published
    9 June 2015

  23. Research is needed on the impact of treating Alzheimer's disease on mortality and institutionalisation, and to assess the relationship between disease progression and carer utility (quality of life).

    guidance Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease Number TA217 Date issued March

    Research recommendation
    Published
    9 June 2015

  24. Antibiotics for suspected early-onset infection: What is the incidence in England and Wales of resistance to commonly used antibiotics among bacteria that cause early-onset neonatal infection?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  25. Information and support: What is the clinical and cost effectiveness of information and support offered to parents and carers of babies who have received antibiotics for suspected or proven early-onset neonatal infection?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  26. Antibiotics for suspected early-onset infection: What are the core exposures and outcomes that should be used to evaluate clinical effectiveness of antibiotics to prevent or treat early- onset neonatal infection?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  27. Further research designed to investigate differences in health-related quality of life and the clinical effectiveness of bevacizumab in subgroups, such as those with prior taxane exposure, would be particularly useful.

    guidance Bevacizumab in combination with a taxane for the first-line treatment of metastatic breast cancer Number TA214 Date issued

    Research recommendation
    Published
    9 June 2015

  28. Further research on the clinical effectiveness of rivaroxaban compared with low molecular weight heparin (LMWH) in patients with active cancer should be conducted.

    Source guidance details Comes from guidance Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein...

    Research recommendation
    Published
    9 June 2015

  29. Further collection of quality of life data from people who are cured and who have experience of amputation and chemotherapy are also needed. Additional data on the health effects on parents, siblings and others with life-threatening illness would also be of value.

    Source guidance details Comes from guidance Mifamurtide for the treatment of osteosarcoma Number TA235 Date issued October 2011

    Research recommendation
    Published
    9 June 2015

  30. Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's disease on both short-term and long-term outcomes, disease progression through relevant health states, and quality of life.

    guidance Donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease Number TA217 Date issued March

    Research recommendation
    Published
    9 June 2015

  31. People who are concerned about their fertility should be informed that the effectiveness of complementary therapies for fertility problems has not been properly evaluated and that further research is needed before such interventions can be recommended. [2004]

    details Comes from guidance Fertility problems: assessment and treatment Number CG156 Date issued February 2013 Other

    Research recommendation
    Published
    9 June 2015

  32. Hybrid closed loop systems for managing blood glucose levels in type 1 diabetes (TA943)

    Evidence-based recommendations on hybrid closed loop systems for managing blood glucose levels in type 1 diabetes.

    Technology appraisal guidance
    Published
    19 December 2023
    View recommendations

    Sections for TA943

  33. Evinacumab for treating homozygous familial hypercholesterolemia in children aged 6 months to 11 [TSID11806]

    Topic prioritisation

    Technology appraisal guidance
    Topic prioritisation

  34. A trial comparing the long-term effectiveness (beyond 24 weeks) of cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate and placebo would be beneficial. It should collect utility data as well as walking distance outcomes.

    naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral...

    Research recommendation
    Published
    9 June 2015

  35. The Committee recommends that a study estimating utility values using directly observed health-related quality of life values (such as EQ 5D scores) in patients with myelodysplastic syndromes, chronic myelomonocytic leukaemia or acute myeloid leukaemia is conducted.

    Source guidance details Comes from guidance Azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia...

    Research recommendation
    Published
    9 June 2015

  36. The Committee considered that rigorous data collection is needed on the life-extending benefits of lenalidomide when used in people with multiple myeloma who have received two or more prior therapies.

    guidance details Comes from guidance Lenalidomide for the treatment of multiple myeloma in people who have received at least 2 prior...

    Research recommendation
    Published
    25 October 2019

  37. Investigations for babies who may have early-onset infection: What is the clinical and cost effectiveness of laboratory investigations used individually or in combination to exclude early-onset neonatal infection in babies receiving antibiotics for suspected infection?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  38. FebriDx for C-reactive protein and myxovirus resistance protein A testing (MIB224)

    NICE has developed a medtech innovation briefing (MIB) on FebriDx for C-reactive protein and myxovirus resistance protein A testing .

    Medtech innovation briefing
    Published
    26 August 2020

  39. Icare rebound tonometer to measure intraocular pressure (MIB57)

    NICE has developed a medtech innovation briefing (MIB) on the Icare rebound tonometer to measure intraocular pressure

    Medtech innovation briefing
    Published
    15 March 2016

  40. Active B12 assay for diagnosing vitamin B12 deficiency (MIB40)

    NICE has developed a medtech innovation briefing (MIB) on the Active-B12 assay for diagnosing vitamin B12 deficiency

    Medtech innovation briefing
    Published
    30 September 2015

  41. What is the effect of dietary interventions or dietary changes on acne?

    committee's discussion are in evidence review C: dietary interventions for the treatment of acne vulgaris. Source guidance details Comes...

    Research recommendation
    Published
    3 May 2024

  42. Diet: What is the effect of dietary interventions or dietary changes on acne?

    committee's discussion are in evidence review C: dietary interventions for the treatment of acne vulgaris. Source guidance details Comes...

    Research recommendation
    Published
    10 August 2021

  43. Totally endoscopic robotically assisted coronary artery bypass grafting (IPG128)

    Evidence-based recommendations on totally endoscopic robotically assisted coronary artery bypass grafting (TECAB). This involves using small, remote-controlled robotic arms to carry out the grafting procedure.

    Interventional procedures guidance
    Published
    22 June 2005
    View recommendations

    Sections for IPG128

  44. Stent-graft placement in abdominal aortic aneurysm (IPG163)

    Evidence-based recommendations on stent-graft placement in abdominal aortic aneurysm. This involves patching the weakened section of the aorta with a graft mounted on a stent.

    Interventional procedures guidance
    Published
    22 March 2006
    View recommendations

    Sections for IPG163

  45. Exenatide prolonged-release suspension for injection in combination with oral antidiabetic therapy for the treatment of type 2 diabetes (TA248)

    This guidance has been updated and replaced by NICE guideline NG28.

    Technology appraisal guidance
    Published
    22 February 2012

  46. Erlotinib in combination with bevacizumab for the second line treatment of advanced or metastatic non-small cell lung cancer [ID43]

    Discontinued Reference number: GID-TA11207

    Technology appraisal guidance
    Discontinued

  47. Complex PTSD:- What is the clinical and cost effectiveness of interventions to deliver stabilisation and reintegration for people with complex PTSD?

    psychological, psychosocial and other non-pharmacological interventions for the treatment of PTSD in adults. Source guidance details...

    Research recommendation
    Published
    13 February 2019

  48. Intrapartum antibiotics: What is the clinical and cost effectiveness of intrapartum antibiotics for women with meconium-stained amniotic fluid?

    from guidance Neonatal infection: antibiotics for prevention and treatment Number NG195 Date issued April 2021 Other details

    Research recommendation
    Published
    6 August 2021

  49. What is the impact of drug-related adverse effects on health economics and quality of life in neuropathic pain?

    about how this affects cost of the quality of life of patients receiving treatment. Source guidance details Comes from guidance...

    Research recommendation
    Published
    26 October 2020

  50. What is the efficacy of reduced dose oral isotretinoin in the management of acne vulgaris?

    recommendation for research, see the rationale section on oral isotretinoin treatment . Full details of the evidence and the committee's...

    Research recommendation
    Published
    3 May 2024