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Evidence-based recommendations on interferon alfa (Pegasys or ViraferonPeg) and ribavirin for people with chronic hepatitis C.
Our centralised approach to prioritising our guidance topics ensures that we produce guidance that's relevant, timely, accessible, and has demonstrable impact.
Learning disabilities and behaviour that challenges: service design and delivery (NG93)
This guideline covers services for children, young people and adults with a learning disability (or autism and a learning disability) and behaviour that challenges. It aims to promote a lifelong approach to supporting people and their families and carers, focusing on prevention and early intervention and minimising inpatient admissions.
This guide gives an overview of the process for developing evidence summaries. Evidence summaries provide advice but do not include recommendations and are not formal NICE guidance
also needed to understand the long-term impact of duration on costs and patient outcomes, by comparing 6-week reablement services with...
NICE Advice - a fee-based advisory service for pharmaceutical and healthtech companies seeking to enter the NHS market,
Data on the cancer recommendations made by our technology appraisal programme. Includes information on the number of positive recommendations we've made.
Eteplirsen for treating Duchenne muscular dystrophy [ID1003]
Discontinued Reference number: GID-HST10007
Discontinued Reference number: GID-TA10072
Elivaldogene autotemcel for treating cerebral adrenoleukodystrophy [ID1284]
Discontinued Reference number: GID-HST10038
Discontinued Reference number: GID-TA10739
Emapalumab for treating primary haemophagocytic lymphohistiocytosis (ID1438)
Discontinued Reference number: GID-TA10527
Hepatitis B and C testing: people at risk of infection (PH43)
This guideline covers raising awareness of and testing for hepatitis B and C infection. It aims to ensure that people at increased risk of hepatitis B and C infection are tested.
This guideline covers planning and delivering multi-agency services for domestic violence and abuse. It aims to help identify, prevent and reduce domestic violence and abuse among women and men in heterosexual or same-sex relationships, and among young people.
Generalised anxiety disorder and panic disorder in adults: management (CG113)
This guideline covers the care and treatment of people aged 18 and over with generalised anxiety disorder (chronic anxiety) or panic disorder (with or without agoraphobia or panic attacks). It aims to help people achieve complete relief of symptoms (remission), which is associated with better functioning and a lower likelihood of relapse.
Discontinued Reference number: GID-TA10566
Any explanatory notes(if applicable) Why this is important:- In patients with submucosal (T1b) N0 oesophageal adenocarcinoma (OAC), the...
Discontinued Reference number: GID-TA10310
the research into the optimum treatment for varicose veins has involved patients with varicose veins in CEAP stages C2 and C3, so little...
Methods for the development of NICE public health guidance (third edition) (PMG4)
This manual describes the methods used by the Centre for Public Health Excellence (CPHE) in NICE to develop and update public health guidance
bone mineral density (BMD). Input of BMD into the questionnaire in such patients will therefore generate the same fracture risk whether...
there is little empirical evidence to guide healthcare professionals or patients in choosing which disorder should be treated first....
or more years. Neither FRAX nor QFracture has been examined in treated patients, and it is not known whether the ability of clinical...
NICE has developed a medtech innovation briefing (MIB) on Coban 2 for venous leg ulcers .
fracture risk possible at the time of consultation. However, refinement of a patient's 10-year fracture risk using BMD requires...
can progress to fibrosis, cirrhosis and hepatocellular cancer. In most patients NAFLD is asymptomatic and is only detected incidentally...
medical patients in the UK have prophylaxis when the national tool has been used, with some trusts offering prophylaxis to over 90% of...
Our framework agreement allows UK NHS, health and social care organisations to buy knowledge resources that support practice, learning and development.
Fetal cystoscopy for the diagnosis and treatment of lower urinary outflow tract obstruction (HTG131)
Evidence-based recommendations on fetal cystoscopy for the diagnosis and treatment of lower urinary outflow tract obstruction. This involves inserting a tube with a flexible camera through small cuts in the mother's abdomen to identify and open any blockage.
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Sections for HTG131
there is very sparse evidence about which strategies are most acceptable to patients and/or their family members and carers. The current...
generally remains for life. Current clinical experience suggests that most patients in a community setting who are believed to be...
Why this is important:- Multidisciplinary care improves survival in patients with MND. The evidence is drawn from models of...
Urinary tract infection (catheter-associated): antimicrobial prescribing (NG113)
This guideline sets out an antimicrobial prescribing strategy for catheter-associated urinary tract infection in children, young people and adults. It aims to optimise antibiotic use and reduce antibiotic resistance.
Vitamin D: supplement use in specific population groups (PH56)
This guideline covers vitamin D supplement use. It aims to prevent vitamin D deficiency among specific population groups including infants and children aged under 4, pregnant and breastfeeding women, particularly teenagers and young women, people over 65, people who have low or no exposure to the sun and people with dark skin.
of cirrhosis. Approximately half of patients with cirrhosis have oesophageal varices, and one-third of all patients with...
needs or incontinence and visual impairment are common in older hospital patients. Several multifactorial studies have included...
conditions are limited to small numbers of patients within case series studies that include heterogeneous groups of...
Framingham or Bonn veins studies, should be undertaken. The study should recruit patients with C2 and C3 disease and follow the progress...
treatment-related morbidity and mortality. In a very small percentage of patients with squamous carcinoma involving a cervical lymph...
that ambulatory oxygen therapy is effective in achieving these aims in patients with idiopathic pulmonary fibrosis. A randomised...
Transition between inpatient mental health settings and community or care home settings (NG53)
This guideline covers the period before, during and after a person is admitted to, and discharged from, a mental health hospital. It aims to help people who use mental health services, and their families and carers, to have a better experience of transition by improving the way it’s planned and carried out.
early intervention with systemic treatments alters prognosis. Consequently, patients with more severe disease sequence through all...
Evidence-based recommendations on septostomy with or without amnioreduction for treating twin-to-twin transfusion syndrome. This involves creating a small hole in the membrane between the babies to allow the amniotic fluid to move from one baby to the other, so both babies have a more equal amount of amniotic fluid.
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Sections for HTG127
Evidence-based recommendations on cabotegravir (Vocabria) with rilpivirine (Rekambys) for treating HIV-1 in adults. This includes adults with virological suppression (HIV-1 RNA fewer than 50 copies/ml) on a stable antiretroviral regimen, and without any evidence of viral resistance to, and no previous virological failure with, any non-nucleoside reverse transcriptase inhibitors or integrase inhibitors.
dietary advice to address the common questions asked by newly diagnosed patients on preventing disease progression. However, although...
Perioperative Quality Improvement Programme (PQIP) 2017/2018 annual report, 61% of patients enrolled in the PQIP were following an ERP....
NICE joins international collaboration on HTA methods research
We’ve partnered with the USA-based Institute for Clinical and Economic Review (ICER) and the Canadian Drug Agency (CDA-AMC) to establish the Health Economics Methods Advisory (HEMA), a new international initiative to research and evaluate health technology assessment (HTA) methods.
NICE has developed a medtech innovation briefing (MIB) on Accuro for guiding epidural or spinal anaesthesia .
Deferred tributary treatment may reduce morbidity, and also mean that some patients do not need tributary treatment (or need fewer...
Onasemnogene abeparvovec for treating presymptomatic spinal muscular atrophy (HST24)
Evidence-based recommendations on onasemnogene abeparvovec (Zolgensma) for treating presymptomatic spinal muscular atrophy in babies aged 12 months and under.