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Showing 2501 to 2550 of 2990 results for all

  1. ClearWay RX for drug delivery to coronary artery thrombotic lesions (MIB55)

    NICE has developed a medtech innovation briefing (MIB) on ClearWay RX for drug delivery to coronary artery thrombotic lesions

  2. Pemetrexed for the maintenance treatment of non-small-cell lung cancer (TA190)

    Evidence-based recommendations on pemetrexed disodium (Alimta) for the maintenance treatment of non-small-cell lung cancer.

  3. Dabrafenib with trametinib for adjuvant treatment of resected BRAF V600 mutation-positive melanoma (TA544)

    Evidence-based recommendations on dabrafenib (Tafinlar) with trametinib (Mekinist) for resected stage III, BRAF V600 mutation-positive melanoma in adults.

  4. Pemetrexed for the first-line treatment of non-small-cell lung cancer (TA181)

    Evidence-based recommendations on pemetrexed for untreated non-small-cell lung cancer in adults.

  5. Type 2 diabetes mellitus in adults: high-strength insulin glargine 300 units/ml (Toujeo) (ESNM65)

    Summary of the evidence on high-strength insulin glargine 300 units/ml (Toujeo) for type 2 diabetes mellitus to inform local NHS planning and decision-making

  6. What is the relative effectiveness and cost effectiveness of different oral fluids and different oral fluid regimens, both with and without oral N-acetylcysteine, at preventing contrast-induced acute kidney injury?

    at particularly high risk and that oral hydration should be encouraged in all other adults at increased risk of contrast-induced acute...

  7. What interventions are effective and cost effective in supporting return to work after recurrent short-term sickness absence in the UK?

    they are properly implemented. The committee agreed that it is important for all sizes of organisation to clearly communicate policies...

  8. Atrial fibrillation and heart valve disease: self-monitoring coagulation status using point-of-care coagulometers (the CoaguChek XS system) (HTG353)

    Evidence-based recommendations on the CoaguChek XS system for self-monitoring coagulation status in adults and children. The recommendations originally included the InRatio2 PT/INR, but this was withdrawn from the market in October 2016 and is not currently available.

  9. U-Drain for people needing night drainage of urine or dialysis fluid (MIB95)

    NICE has developed a medtech innovation briefing (MIB) on U-Drain for people needing night drainage of urine or dialysis fluid .

  10. Needle-free arterial non-injectable connector (MIB85)

    NICE has developed a medtech innovation briefing (MIB) on the needle-free arterial non-injectable connector .

  11. Percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic events (HTG325)

    Evidence-based recommendations on percutaneous closure of the patent foramen ovale for the prevention of cerebral embolic stroke. This involves placing a small device into the heart to close the hole.

  12. Point-of-care tests for urinary tract infections to improve antimicrobial prescribing: early value assessment (HTG674)

    Early value assessment (EVA) guidance on point-of-care tests for urinary tract infections to improve antimicrobial prescribing.

  13. Bipolar disorder, psychosis and schizophrenia in children and young people (QS102)

    This quality standard covers recognition, early intervention and long-term management of bipolar disorder, psychosis and schizophrenia in children and young people (under 18). It also includes support for parents and carers. It describes high-quality care in priority areas for improvement.

  14. Acute respiratory infection in over 16s: initial assessment and management including virtual wards (hospital at home) (QS210)

    This quality standard covers the initial assessment and management of suspected acute respiratory infection in over 16s, including acute respiratory infection virtual wards.

  15. Digitally enabled therapies for adults with depression: early value assessment (HTG675)

    Early value assessment (EVA) guidance on digitally enabled therapies for adults with depression.

  16. Faltering growth: recognition and management of faltering growth in children (NG75)

    This guideline covers recognition, assessment and monitoring of faltering growth in infants and children. It includes a definition of growth thresholds for concern and identifying the risk factors for, and possible causes of, faltering growth. It also covers interventions, when to refer, service design, and information and support.

  17. Cataracts in adults: management (NG77)

    This guideline covers managing cataracts in adults aged 18 and over. It aims to improve care before, during and after cataract surgery by optimising service organisation, referral and surgical management, and reducing complications. It further aims to improve the availability of information for people with cataracts before, during and after cataract surgery.

  18. Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and management (CG84)

    This guideline covers diagnosing, managing and referring infants and young children younger than 5 years who present with acute diarrhoea (lasting up to 14 days) with or without vomiting. It aims to improve the diagnosis and management of infective gastroenteritis and appropriate escalation of care.

  19. What interventions are effective and cost effective at raising awareness of the health risks of damp and mould in the home?

    landlords, and those who regulate them.Similarly, the committee agreed that not all professionals who see people in their home know who...

  20. What are the most effective and cost-effective interventions to challenge stereotypes and change employers' and workforce attitudes towards older employees?

    attitudes and reducing stereotyping may result in people working for longer, with all the associated benefits for them and society....

  21. Artificial intelligence (AI)-derived software to help clinical decision making in stroke (HTG708)

    Evidence-based recommendations on artificial intelligence-derived software to help clinical decision making in stroke.

  22. What is the best way of monitoring the local system for distributing vitamin D supplements?

    adherence or any unintentional consequences. The recommendations apply to all at-risk groups, but there is a particular need for...

  23. Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustment (HTG360)

    Evidence-based recommendations on the My5-FU assay for measuring levels of 5-flurouracil (5-FU) in patients having chemotherapy, to help guide changes to the dose of 5-FU.

  24. What is the clinical and cost effectiveness of preoperative optimisation clinics for older people?

    identified during the preoperative assessment. These clinics are not available in all areas and are expensive to establish. Although a...

  25. For people with iron-deficiency anaemia, how long before surgery should oral iron supplementation be started, and what is the clinical and cost effectiveness of daily oral iron compared with oral iron given on alternate days?

    identified during the preoperative assessment. These clinics are not available in all areas and are expensive to establish. Although a...

  26. Pharmacological interventions – gabapentinoids and local anaesthetics for complex regional pain syndrome: What is the clinical and cost effectiveness of gabapentinoids or local anaesthetics for managing complex regional pain syndrome in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  27. Psychotherapy for chronic primary pain: What is the clinical and cost effectiveness of psychodynamic psychotherapy for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  28. Manual therapies for chronic primary pain: What is the clinical and cost effectiveness of manual therapy for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  29. Relaxation therapy for chronic primary pain: What is the clinical and cost effectiveness of relaxation therapies for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  30. Factors that may be barriers to successfully managing chronic pain, including chronic primary pain: What risk factors enable stratification of treatment for people aged 16 years and over with chronic pain?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  31. Transcranial magnetic stimulation for chronic primary pain: What is the clinical and cost effectiveness of transcranial magnetic stimulation for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  32. Psychological therapy – CBT for insomnia in chronic primary pain: What is the clinical and cost effectiveness of cognitive behavioural therapy (CBT) for insomnia or CBT for insomnia and pain for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  33. Repeat courses of acupuncture for chronic primary pain: What is the clinical and cost effectiveness of repeat courses of acupuncture or dry needling for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  34. Social interventions for chronic pain, including chronic primary pain: What is the clinical and cost effectiveness of social interventions aimed at improving the quality of life of people aged 16 years and over with chronic pain?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  35. Laser therapy for chronic primary pain: What is the clinical and cost effectiveness of laser therapy for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  36. Psychological therapy – mindfulness for chronic primary pain: What is the clinical and cost effectiveness of mindfulness therapy for managing chronic primary pain in people aged 16 years and over?

    guidance Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain Number...

  37. How can a multiagency approach to improving awareness, availability and uptake of vitamin D supplements best be established, improved and sustained?

    adherence or any unintentional consequences. The recommendations apply to all at-risk groups, but there is a particular need for...

  38. Antimicrobial prescribing: delafloxacin for community-acquired pneumonia (ES37)

    Summary of the evidence on delafloxacin for community-acquired pneumonia in adults

  39. What is the clinical and cost effectiveness of budesonide for treating COVID-19 in the community in adults, young people and children?

    I: Inhaled budesonide C: Inhaled placebo (to accommodate blinding) O:• All-cause mortality• Hospitalisation• Need for oxygen therapy...

  40. i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department (MIB38)

    NICE has developed a medtech innovation briefing (MIB) on i STAT CG4+ and CHEM8+ cartridges for point-of-care testing in the emergency department

  41. What is the most clinical and cost-effective strategy, as identified by a consensus survey, for the perioperative management of anticoagulation treatment in people taking a vitamin K antagonist with a target international normalised ratio (INR) of more than 3 who need bridging therapy?

    identified during the preoperative assessment. These clinics are not available in all areas and are expensive to establish. Although a...

  42. Tegaderm CHG securement dressing for vascular access sites in critically ill adults (HTG379)

    Evidence-based recommendations on Tegaderm CHG securement dressing for vascular access sites in critically ill adults.

  43. Laparoscopic gastric plication for the treatment of severe obesity (HTG293)

    Evidence-based recommendations on laparoscopic gastric plication for the treatment of morbid obesity. This involves folding the stomach in on itself and stitching it together to reduce its volume.

  44. Partial replacement of the meniscus of the knee using a biodegradable scaffold (HTG289)

    Evidence-based recommendations on partial replacement of the meniscus of the knee using a biodegradable scaffold. This involves placing a biodegradable implant into the meniscus to support regrowth and repair of the damage.

  45. What is the effectiveness and safety of a treatment dose with a low molecular weight heparin (LMWHs) compared with a standard prophylactic dose for venous thromboembolism (VTE) prophylaxis in young people under 18 years with COVID-19?

    LMWH C: standard prophylaxis with LMWH O:• incidence of VTE• mortality (all-cause, inpatient, COVID-19 related)• admission to critical...

  46. Self-management:- Do structured psoriasis-focused self-management programmes improve patient confidence, wellbeing and disease control compared with standard care?

    Any explanatory notes(if applicable) Why this is important:- Virtually all patients self-manage their condition to a greater or lesser...

  47. Warming in patients with major trauma:- Is warming clinically and cost effective in patients with major trauma? If so, which groups of patients will benefit from warming and what is the best method of warming?

    is uncertainty about the clinical benefit of warming patients and whether all groups of patients would benefit from warming. In...

  48. Monitoring pulmonary disease:- Is lung clearance index a useful and cost-effective tool for the routine assessment and monitoring of changes in pulmonary status in people with cystic fibrosis?

    Assessing the severity of lung disease is difficult in younger children. Not all children under 5 years can do spirometry tests and they...

  49. Cannabidiol for treating seizures caused by tuberous sclerosis complex (TA873)

    Evidence-based recommendations on cannabidiol (Epidyolex) for treating seizures caused by tuberous sclerosis complex.

  50. What type of training and awareness-raising can improve how health and social care practitioners: - promote vitamin D supplements among at-risk groups - improve the local population's awareness of, and attitudes towards, vitamin D supplements - uptake of vitamin D supplements?

    adherence or any unintentional consequences. The recommendations apply to all at-risk groups, but there is a particular need for...