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Unstable angina and NSTEMI: early management (CG94)

This guideline covers treatments for people aged 18 and over with unstable angina (recurring chest pain) or a type of heart attack called non-ST-segment-elevation myocardial infarction (NSTEMI). It aims to ensure that people get treatment quickly. It recommends that as soon as NSTEMI or unstable angina is diagnosed, healthcare professionals assess people for risk of more serious heart problems in the future to guide their treatment.

Clinical guideline Published March 2010 Last updated November 2013

Chest pain of recent onset: assessment and diagnosis (CG95)

This guideline covers assessing and diagnosing recent chest pain in people aged 18 and over and managing symptoms while a diagnosis is being made. It aims to improve outcomes by providing advice on tests (ECG, high-sensitivity troponin tests, multislice CT angiography, functional testing) that support healthcare professionals to make a speedy and accurate diagnosis.

Clinical guideline Published March 2010 Last updated November 2016

Lower urinary tract symptoms in men: management (CG97)

This guideline covers managing lower urinary tract symptoms (LUTS) in men over 18. It aims to improve the quality of life for men with LUTS by recommending which assessments they should receive, and when conservative management, drug treatment and surgery can help.

Clinical guideline Published May 2010 Last updated June 2015

Respiratory tract infections (self-limiting): prescribing antibiotics (CG69)

This guideline covers prescribing antibiotics in primary care to children (aged 3 months and older), young people and adults with self-limiting respiratory tract infections (RTIs). It provides practical strategies for prescribing, including identifying when immediate antibiotics are needed and when to offer a delayed prescription or reassurance alone. It covers identifying who is at risk of serious illness but not investigations or further care for people needing immediate antibiotics.

Clinical guideline Published July 2008

Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures (CG64)

This guideline covers preventing infective endocarditis (IE) in children, young people and adults. It focuses on people at increased risk of infective endocarditis undergoing dental, gastrointestinal tract, genitourinary and respiratory tract procedures.

Clinical guideline Published March 2008 Last updated July 2016

Inducing labour (CG70)

This guideline covers circumstances, methods and monitoring for inducing labour in pregnant women to avoid a pregnancy lasting longer than 42 weeks (known as a prolonged pregnancy) or if a woman’s waters break but labour does not start. It aims to improve the advice and care provided to women considering and undergoing induction of labour in hospital-based maternity units, midwifery led units and at home .

Clinical guideline Published July 2008

Otitis media with effusion in under 12s: surgery (CG60)

This guideline covers surgical treatment of children younger than 12 years who have fluid buildup behind their eardrum (otitis media, also known as ‘glue ear’). It aims to improve hearing and quality of life in children with otitis media.

Clinical guideline Published February 2008

Oral health promotion: general dental practice (NG30)

This guideline covers how general dental practice teams can convey advice about oral hygiene and the use of fluoride. It also covers diet, smoking, smokeless tobacco and alcohol intake.

NICE guideline Published December 2015

Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over (NG36)

This guideline covers assessing and managing cancers of the upper aerodigestive tract in people aged 16 and over. These are cancers of the airways of the head and neck, including the mouth, throat, larynx (voicebox) and sinuses. It aims to reduce variation in practice and improve survival.

NICE guideline Published February 2016 Last updated June 2018

Antimicrobial stewardship: systems and processes for effective antimicrobial medicine use (NG15)

This guideline covers the effective use of antimicrobials (including antibiotics) in children, young people and adults. It aims to change prescribing practice to help slow the emergence of antimicrobial resistance and ensure that antimicrobials remain an effective treatment for infection.

NICE guideline Published August 2015

Dementia, disability and frailty in later life – mid-life approaches to delay or prevent onset (NG16)

This guideline covers mid-life approaches to delay or prevent the onset of dementia, disability and frailty in later life. The guideline aims to increase the amount of time that people can be independent, healthy and active in later life.

NICE guideline Published October 2015

Prostate cancer: diagnosis and management (NG131)

This guideline covers the diagnosis and management of prostate cancer in secondary care, including information on the best way to diagnose and identify different stages of the disease, and how to manage adverse effects of treatment. It also includes recommendations on follow-up in primary care for people diagnosed with prostate cancer.

NICE guideline Published May 2019

Older people with social care needs and multiple long-term conditions (NG22)

This guideline covers planning and delivering social care and support for older people who have multiple long-term conditions. It promotes an integrated and person-centred approach to delivering effective health and social care services.

NICE guideline Published November 2015

Menopause: diagnosis and management (NG23)

This guideline covers the diagnosis and management of menopause, including in women who have premature ovarian insufficiency. The guideline aims to improve the consistency of support and information provided to women in menopause.

NICE guideline Published November 2015

Blood transfusion (NG24)

This guideline covers the assessment for and management of blood transfusions in adults, young people and children over 1 year old. It covers the general principles of blood transfusion, but does not make recommendations relating to specific conditions.

NICE guideline Published November 2015

Preterm labour and birth (NG25)

This guideline covers the care of women at increased risk of or with symptoms and signs of preterm labour (before 37 weeks) and women having a planned preterm birth. It aims to reduce the risks of preterm birth for the baby and describes treatments to prevent or delay early labour and birth.

NICE guideline Published November 2015

Suspected cancer: recognition and referral (NG12)

This guideline covers identifying children, young people and adults with symptoms that could be caused by cancer. It outlines appropriate investigations in primary care, and selection of people to refer for a specialist opinion. It aims to help people understand what to expect if they have symptoms that may suggest cancer.

NICE guideline Published June 2015 Last updated July 2017

Major trauma: service delivery (NG40)

This guideline covers the organisation and provision of major trauma services in pre-hospital and hospital settings, including ambulance services, emergency departments, major trauma centres and trauma units. It aims to reduce deaths and disabilities in people with serious injuries by providing a systematic approach to the delivery of major trauma care. It does not cover services for people with burns.

NICE guideline Published February 2016

Motor neurone disease: assessment and management (NG42)

This guideline covers assessing and managing motor neurone disease (MND). It aims to improve care from the time of diagnosis, and covers information and support, organisation of care, managing symptoms and preparing for end of life care.

NICE guideline Published February 2016

Safe midwifery staffing for maternity settings (NG4)

This guideline covers safe midwifery staffing in all maternity settings, including at home, in the community, in day assessment units, in obstetric units, and in units led by midwives (both alongside hospitals and free-standing). It aims to improve maternity care by giving advice on monitoring staffing levels and actions to take if there are not enough midwives to meet the needs of women and babies in the service.

NICE guideline Published February 2015

Ectopic pregnancy and miscarriage: diagnosis and initial management (NG126)

This guideline covers diagnosing and managing ectopic pregnancy and miscarriage in women with complications, such as pain and bleeding, in early pregnancy (that is, up to 13 completed weeks of pregnancy). It aims to improve how early pregnancy loss is diagnosed, and the support women are given, to limit the psychological impact of their loss.

NICE guideline Published April 2019

Intravenous fluid therapy in children and young people in hospital (NG29)

This guideline covers general principles for managing intravenous (IV) fluids for children and young people under 16 years, including assessing fluid and electrolyte status and prescribing IV fluid therapy. It applies to a range of conditions and different settings. It does not include recommendations relating to specific conditions. This guideline represents a major opportunity to improve patient safety for children and young people having IV fluid therapy in hospital.

NICE guideline Published December 2015

Diabetes in pregnancy: management from preconception to the postnatal period (NG3)

This guideline covers managing diabetes and its complications in women who are planning pregnancy or are already pregnant. It aims to improve the diagnosis of gestational diabetes and help women with diabetes to self-manage their blood glucose levels before and during pregnancy.

NICE guideline Published February 2015 Last updated August 2015

Transition from children's to adults' services for young people using health or social care services (NG43)

This guideline covers the period before, during and after a young person moves from children's to adults' services. It aims to help young people and their carers have a better experience of transition by improving the way it’s planned and carried out. It covers both health and social care.

NICE guideline Published February 2016

Pregnancy and complex social factors: a model for service provision for pregnant women with complex social factors (CG110)

This guideline covers antenatal care for all pregnant women with complex social factors (particularly alcohol or drug misuse, recent migrant or asylum seeker status, difficulty reading or speaking English, aged under 20, domestic abuse). It offers advice on improving access to care, maintaining contact with antenatal carers, and additional information and support for these women.

Clinical guideline Published September 2010

Sedation in under 19s: using sedation for diagnostic and therapeutic procedures (CG112)

This guideline covers the assessment, preparation, training and monitoring needed when using sedation in people aged under 19. It aims to help healthcare professionals decide when sedation is the most clinically and cost effective option for reducing pain and anxiety during operations for children and young people.

Clinical guideline Published December 2010

Generalised anxiety disorder and panic disorder in adults: management (CG113)

This guideline covers the care and treatment of people aged 18 and over with generalised anxiety disorder (chronic anxiety) or panic disorder (with or without agoraphobia or panic attacks). It aims to help people achieve complete relief of symptoms (remission), which is associated with better functioning and a lower likelihood of relapse.

Clinical guideline Published January 2011

Organ donation for transplantation: improving donor identification and consent rates for deceased organ donation (CG135)

This guideline covers identifying people who wish to donate their organs after their death. It offers advice on how to approach families and carers of people who are nearing the end of life and how to seek consent for organ donation. It aims to promote discussion of organ donation as part of end-of-life care and to increase the number of organs available for people waiting for a transplant.

Clinical guideline Published December 2011 Last updated December 2016

Hip fracture: management (CG124)

This guideline covers managing hip fracture in adults. It aims to improve care from the time people aged 18 and over are admitted to hospital through to when they return to the community. Recommendations emphasise the importance of early surgery and coordinating care through a multidisciplinary hip fracture programme to help people recover faster and regain their mobility.

Clinical guideline Published June 2011 Last updated May 2017

Transient loss of consciousness ('blackouts') in over 16s (CG109)

This guideline covers assessment, diagnosis and referral for people over 16 who have had a transient loss of consciousness (TLoC; also called a blackout). It aims to improve care for people with TLoC by specifying the most effective assessments and recommending when to refer to a specialist.

Clinical guideline Published August 2010 Last updated September 2014

Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence (CG115)

This guideline covers identifying, assessing and managing alcohol-use disorders (harmful drinking and alcohol dependence) in adults and young people aged 10–17 years. It aims to reduce harms (such as liver disease, heart problems, depression and anxiety) from alcohol by improving assessment and setting goals for reducing alcohol consumption.

Clinical guideline Published February 2011

Hypertension in adults: diagnosis and management (CG127)

This guideline covers identifying and treating primary hypertension (high blood pressure) in people aged 18 and over. It aims to reduce the risk of cardiovascular problems such as heart attacks and strokes by helping healthcare professionals to diagnose hypertension accurately and treat it effectively. It also aims to reduce unnecessary treatment by improving the way blood pressure is measured.

Clinical guideline Published August 2011 Last updated November 2016

Metastatic malignant disease of unknown primary origin in adults: diagnosis and management (CG104)

This guideline covers diagnosing and managing secondary cancers in people aged 18 and over when the site of the primary cancer is unknown. This includes people who have had treatment for cancer before. It aims to improve quality of life by offering advice on tests for identifying the site of the primary cancer and options for managing the person’s condition when this cannot be found.

Clinical guideline Published July 2010

Barrett's oesophagus: ablative therapy (CG106)

This guideline covers endoscopy treatments for people aged 18 and over with Barrett’s oesophagus and high-grade dysplasia or intramucosal cancer. It offers advice on which types of endoscopy treatments should be offered and how these should be used. It aims to improve choice of treatment for adults with Barrett’s oesophagus and improve quality of life and survival for those who cannot have surgery.

Clinical guideline Published August 2010

Colorectal cancer: diagnosis and management (CG131)

This guideline covers diagnosing and managing colorectal (bowel) cancer in people aged 18 and over. It aims to improve quality of life and survival for adults with colorectal cancer through early diagnosis and staging, management of local disease according to risk of recurrence (high, moderate, low) and management of secondary tumours (metastatic disease).

Clinical guideline Published November 2011 Last updated December 2014

Medicines optimisation: the safe and effective use of medicines to enable the best possible outcomes (NG5)

This guideline covers safe and effective use of medicines in health and social care for people taking 1 or more medicines. It aims to ensure that medicines provide the greatest possible benefit to people by encouraging medicines reconciliation, medication review, and the use of patient decision aids.

NICE guideline Published March 2015

People's experience in adult social care services: improving the experience of care and support for people using adult social care services (NG86)

This guideline covers the care and support of adults receiving social care in their own homes, residential care and community settings. It aims to help people understand what care they can expect and to improve their experience by supporting them to make decisions about their care.

NICE guideline Published February 2018

Physical activity for children and young people (PH17)

This guideline covers promoting physical activity for children and young people aged under 18 at home, preschool, school and in the community. It includes raising awareness of the benefits of physical activity, listening to what children and young people want, planning and providing spaces and facilities, and helping families build physical activity into their daily lives.

Public health guideline Published January 2009

Workplace health: long-term sickness absence and incapacity to work (PH19)

This guideline covers how to help employees return to work after long-term sickness and how to help people receiving benefits return to employment (paid or unpaid).

Public health guideline Published March 2009

Cardiovascular disease: identifying and supporting people most at risk of dying early (PH15)

This guideline covers the risk of early death from heart disease and other smoking-related illnesses. It aims to reduce the number of people who are disadvantaged dying prematurely by ensuring people have better access to flexible, well-coordinated treatment and support.

Public health guideline Published September 2008

Social and emotional wellbeing in secondary education (PH20)

This guideline covers interventions to support social and emotional wellbeing among young people aged 11–19 years who are in full-time education. It aims to promote good social, emotional and psychological health to protect young people against behavioural and health problems.

Public health guideline Published September 2009

Sexually transmitted infections and under-18 conceptions: prevention (PH3)

This guideline covers one-to-one interventions to prevent sexually transmitted infections (STIs) and under-18 conceptions. The aim is to reduce the transmission of chlamydia and other STIs, including HIV, and reduce the rate of pregnancies among women aged under 18.

Public health guideline Published February 2007

Healthcare-associated infections: prevention and control in primary and community care (CG139)

This guideline covers preventing and controlling healthcare-associated infections in children, young people and adults in primary and community care settings. It provides a blueprint for the infection prevention and control precautions that should be applied by everyone involved in delivering NHS care and treatment.

Clinical guideline Published March 2012 Last updated February 2017

Palliative care for adults: strong opioids for pain relief (CG140)

This guideline covers safe and effective prescribing of strong opioids for pain relief in adults with advanced and progressive disease. It aims to clarify the clinical pathway for prescribing and help to improve pain management and patient safety. Care during the last 2 to 3 days of life is covered by care of dying adults in the last days of life.

Clinical guideline Published May 2012 Last updated August 2016

Acute upper gastrointestinal bleeding in over 16s: management (CG141)

This guideline covers how upper gastrointestinal bleeding can be effectively managed in adults and young people aged 16 years and older. It aims to identify which diagnostic and therapeutic steps are useful so hospitals can develop a structure in which clinical teams can deliver an optimum service for people who develop this condition.

Clinical guideline Published June 2012 Last updated August 2016

Autism spectrum disorder in adults: diagnosis and management (CG142)

This guideline covers diagnosing and managing suspected or confirmed autism spectrum disorder (autism, Asperger’s syndrome and atypical autism) in people aged 18 and over. It aims to improve access and engagement with interventions and services, and the experience of care, for people with autism.

Clinical guideline Published June 2012 Last updated August 2016

Sickle cell disease: managing acute painful episodes in hospital (CG143)

This guideline covers managing acute painful sickle cell episodes in children, young people and adults who present at hospital, from presentation until when they are discharged. It aims to reduce variation in how acute episodes are managed in hospital, focusing on effective, prompt and safe pain relief.

Clinical guideline Published June 2012

Venous thromboembolic diseases: diagnosis, management and thrombophilia testing (CG144)

This guideline covers the diagnosis and management of venous thromboembolic diseases in adults (aged 18 and over), and the role of thrombophilia testing. It aims to clarify which diagnostic tests should be used, reduce variation in pharmacological therapies, and provide guidance on when thrombophilia testing is useful.

Clinical guideline Published June 2012 Last updated November 2015

Chronic kidney disease (stage 4 or 5): management of hyperphosphataemia (CG157)

This guideline covers managing hyperphosphataemia in children, young people and adults with stage 4 or 5 chronic kidney disease. It makes recommendations on dietary management and phosphate binders, to reduce variation in care and the risk of hyperparathyroidism for people with chronic kidney disease.

Clinical guideline Published March 2013

Antisocial behaviour and conduct disorders in children and young people: recognition and management (CG158)

This guideline covers recognising and managing antisocial behaviour and conduct disorders in children and young people aged under 19. It aims to improve care by identifying children and young people who are at risk and when interventions can prevent conduct disorders from developing. The guideline also makes recommendations on communication, to help professionals build relationships with children and young people and involve them in their own care.

Clinical guideline Published March 2013 Last updated April 2017