Search results

Evidence-based recommendations on selective internal radiation therapy for unresectable primary intrahepatic cholangiocarcinoma in adults. This involves injecting tiny radioactive ‘beads’ into blood vessels that supply the liver, where they become trapped and release radiation directly into the cancer cells.

Result type

Interventional procedures guidance

Published

31 October 2018

Evidence-based recommendations on liposuction for chronic lipoedema in adults. This involves using suction to remove abnormal fat.

Result type

Interventional procedures guidance

Published

29 March 2022

Evidence-based recommendations on melphalan chemosaturation with percutaneous hepatic artery perfusion and hepatic vein isolation for primary or metastatic cancer in the liver. This involves diverting the blood flow from the liver to the rest of the body while the drug is delivered directly into the liver.

Result type

Interventional procedures guidance

Published

21 April 2021

Evidence-based recommendations on Barnett Continent Intestinal Reservoir (modified continent ileostomy) to restore continence after colon and rectum removal in adults. This involves using the ileum to create a pouch on the inside of the abdominal wall to collect waste.

Result type

Interventional procedures guidance

Published

20 February 2019

Evidence-based recommendations on single-step scaffold insertion for repairing symptomatic chondral knee defects. This involves inserting a scaffold into the damaged area of the knee to support regrowth and repair of the cartilage.

Result type

Interventional procedures guidance

Last updated

5 August 2025

Evidence-based recommendations on platelet-rich plasma injections for knee osteoarthritis in adults. This involves taking plasma from a small amount of the person’s own blood and injecting it into the knee.

Result type

Interventional procedures guidance

Published

23 January 2019

Evidence-based recommendations on complete cytoreduction for pseudomyxoma peritonei (Sugarbaker technique). This involves complete surgical tumour removal with intraoperative heated chemotherapy, and is followed by postoperative intraperitoneal chemotherapy.

Result type

Interventional procedures guidance

Published

28 April 2004

Evidence-based recommendations on magnetic resonance therapy for knee osteoarthritis in adults. This involves placing a magnetic resonance device over the knee to stimulate cartilage to heal and relieve the symptoms of osteoarthritis.

Result type

Interventional procedures guidance

Published

25 August 2021

Evidence-based recommendations on living-donor liver transplantation. This involves replacing a diseased or damaged liver with a healthy one from a living human donor.

Result type

Interventional procedures guidance

Published

25 November 2015

Evidence-based recommendations on epiduroscopic lumbar discectomy through the sacral hiatus for sciatica in adults. This involves removing the part of the spinal disc pressing against the spinal nerve, to relieve pain.

Result type

Interventional procedures guidance

Published

14 December 2016

Evidence-based recommendations on laparoscopic mobilisation of the greater omentum for breast reconstruction. This involves removing the fatty tissue using special instruments through small cuts in the abdomen.

Result type

Interventional procedures guidance

Published

27 February 2008

Evidence-based recommendations on endoscopic ablation for an anal fistula in adults. This involves applying heat to the fistula.

Result type

Interventional procedures guidance

Published

17 April 2019

Evidence-based recommendations on extracorporeal shockwave therapy for Peyronie's disease. This involves using vibrations caused by sound waves to treat the affected tissue.

Result type

Interventional procedures guidance

Published

17 December 2003

Evidence-based recommendations on transcutaneous neuromuscular electrical stimulation for oropharyngeal dysphagia in adults. This involves electrically stimulating nerves in the throat or neck, while the person swallows. The aim is to strengthen the muscles involved in swallowing.

Result type

Interventional procedures guidance

Published

19 December 2018

Evidence-based recommendations on percutaneous mechanical thrombectomy for acute deep vein thrombosis of the leg in adults. This involves removing the clot through a catheter inserted into the vein.

Result type

Interventional procedures guidance

Published

12 June 2019

Evidence-based recommendations on percutaneous thrombectomy for intermediate-risk or high-risk pulmonary embolism. This involves removing the clot through a catheter inserted into a vein.

Result type

Interventional procedures guidance

Published

29 November 2023

Evidence-based recommendations on cryotherapy for chronic rhinitis. This involves destroying a nerve in the nose to reduce chronic rhinitis symptoms.

Result type

Interventional procedures guidance

Published

14 September 2023

Evidence-based recommendations on transurethral water-jet ablation for lower urinary tract symptoms caused by benign prostatic hyperplasia. This involves injecting a high-speed jet of water into the prostate to destroy some of the prostate tissue and widen the urethra.

Result type

Interventional procedures guidance

Published

14 September 2023

Evidence-based recommendations on minimally invasive fusionless posterior-approach surgery to correct idiopathic scoliosis in children and young people. This involves inserting a rod along the spine through a small cut in the back.

Result type

Interventional procedures guidance

Published

22 June 2023

Evidence-based recommendations on synthetic cartilage implant insertion for first metatarsophalangeal joint osteoarthritis (hallux rigidus). This involves replacing damaged cartilage with an artificial (synthetic) implant.

Result type

Interventional procedures guidance

Published

1 June 2022

Evidence-based recommendations on low-energy contact X-ray brachytherapy for rectal cancer. This involves inserting an X-ray tube through the anus into the rectum. The tube is placed in contact with the tumour and releases a low dose of X-ray radiation (brachytherapy) directly to it.

Result type

Interventional procedures guidance

Published

13 November 2025

Evidence-based recommendations on supercapsular percutaneously assisted total hip arthroplasty for osteoarthritis in adults. This involves replacing a hip using smaller cuts than are used in standard surgery.

Result type

Interventional procedures guidance

Published

25 May 2022

Evidence-based recommendations on venoarterial extracorporeal membrane oxygenation (VA ECMO) for severe acute heart failure in adults. This involves using an artificial lung to oxygenate the blood outside the body.

Result type

Interventional procedures guidance

Published

22 October 2025

Evidence-based recommendations on VA ECMO for extracorporeal cardiopulmonary resuscitation (ECPR) in adults with refractory cardiac arrest. This involves using an artificial lung to oxygenate the blood outside the body.

Result type

Interventional procedures guidance

Published

22 October 2025

Evidence-based recommendations on venoarterial extracorporeal membrane oxygenation (VA ECMO) for postcardiotomy cardiogenic shock in adults. This involves using an artificial lung to oxygenate the blood outside the body.

Result type

Interventional procedures guidance

Published

18 December 2025

Evidence-based recommendations on miniature lens system implantation for advanced age-related macular degeneration. This involves implanting an artificial lens system into 1 eye only.

Result type

Interventional procedures guidance

Published

28 September 2016

Evidence-based recommendations on insertion of a subretinal prosthesis system for retinitis pigmentosa. This involves performing a vitrectomy and implanting a microchip underneath the macula using a transscleral, then subretinal approach.

Result type

Interventional procedures guidance

Published

16 December 2015

Evidence-based recommendations on insertion of an epiretinal prosthesis for retinitis pigmentosa. This involves inserting an implant into the eye that receives data from a small camera on the person's glasses and then stimulates healthy cells in the retina to see basic images.

Result type

Interventional procedures guidance

Published

26 June 2015

Evidence-based recommendations on suture fixation of acute disruption of the distal tibiofibular syndesmosis. This involves threading a suture through a tunnel made in the bones (tibia and fibula) and tying the ends together to fix the joint.

Result type

Interventional procedures guidance

Published

26 June 2015

Evidence-based recommendations on optical coherence tomography to guide percutaneous coronary intervention. This involves using near-infrared light to produce high-resolution images of blood vessel walls.

Result type

Interventional procedures guidance

Published

23 February 2014

Evidence-based recommendations on prosthetic intervertebral disc replacement in the cervical spine. This involves removing the damaged disc and inserting an artificial disc in its place.

Result type

Interventional procedures guidance

Published

19 May 2010

Evidence-based recommendations on selective internal radiation therapy (SIRT) for primary hepatocellular carcinoma. This involves infusion of microspheres loaded with yttrium-90, which aims to deliver radiation directly into the tumour, minimising the risk of radiation damage to healthy surrounding tissues.

Result type

Interventional procedures guidance

Published

23 July 2013

Evidence-based recommendations on photochemical corneal cross linkage using riboflavin and ultraviolet A for keratoconus. This involves using special eye drops and exposing the eye ultraviolet light, with the aim to strengthen the cornea.

Result type

Interventional procedures guidance

Published

25 September 2013

Evidence-based recommendations on endoscopic radiofrequency ablation for Barrett’s oesophagus with low-grade dysplasia or no dysplasia. This involves using radiofrequency (heat) energy to destroy the abnormal cells and promote the growth of healthy normal cells.

Result type

Interventional procedures guidance

Published

23 July 2014

Evidence-based recommendations on minimally invasive video-assisted parathyroidectomy. This involves inserting surgical instruments through a small cut (keyhole surgery) to find and remove any abnormal glands.

Result type

Interventional procedures guidance

Published

23 August 2014

Evidence-based recommendations on single incision laparoscopic cholecystectomy. This involves removing the gallbladder through a small cut, most often below the bellly button.

Result type

Interventional procedures guidance

Published

17 December 2014

Evidence-based recommendations on ultrasound enhanced catheter-directed thrombolysis for deep vein thrombosis. This involves using ultrasound waves and a drug to break up the clot.

Result type

Interventional procedures guidance

Published

26 June 2015

Evidence-based recommendations on ultrasound enhanced catheter-directed thrombolysis for pulmonary embolism. This involves using ultrasound waves and a drug to break up the clot.

Result type

Interventional procedures guidance

Published

26 June 2015

Evidence-based recommendations on epidermal radiotherapy using rhenium-188 paste for non-melanoma skin cancer. This involves radioactive paste being spread on foil over the top of the cancer, to destroy the cancer cells.

Result type

Interventional procedures guidance

Published

2 April 2024

Recommendation ID NG129/1 Question What are the benefits, risk and cost effectiveness of enteral nutrition in maintaining remission in

Result type

Research recommendation

Published

25 October 2019

Recommendation ID CG152/3 Question 5-aminosalicylate (5-ASA) treatment:- Following successful medical induction of remission of Crohn's

Result type

Research recommendation

Published

17 September 2020

Recommendation ID NG156/2 Question What is the effectiveness and cost effectiveness of complex endovascular aneurysm repair (EVAR) versus

Result type

Research recommendation

Published

10 August 2020

Recommendation ID NG156/1 Question What are the most effective and cost-effective frequencies for monitoring people with unruptured abdominal

Result type

Research recommendation

Published

10 August 2020

Recommendation ID NG48/1 Question Access to dental services in England for adults in care homes:- What effect does improving and maintaining

Result type

Research recommendation

Published

24 August 2016

Recommendation ID NG57/5 Question Access to medicines:- Does the use of directly observed supply of named high-risk medicines (that is

Result type

Research recommendation

Published

10 February 2017

Recommendation ID NG198/6 Question What are the risk factors for acne vulgaris-related scarring? Any explanatory notes(if applicable)

Result type

Research recommendation

Published

3 May 2024

Recommendation ID NG72/4 Question Accuracy of the SDQ for predicting social, attentional, emotional and behavioural problems in children

Result type

Research recommendation

Published

15 October 2018

Recommendation ID CG136/4 Question Activities and occupations on inpatient wards:- For people receiving adult mental health hospital care

Result type

Research recommendation

Published

9 June 2015

Recommendation ID NG50/8 Question Acute hepatic encephalopathy:- In people with cirrhosis and an acute episode of hepatic encephalopathy

Result type

Research recommendation

Published

11 January 2024

Recommendation ID CG126/1 Question Adding a newer anti-anginal drug to a calcium channel blocker:- What is the clinical and cost effectiveness

Result type

Research recommendation

Published

9 June 2015