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Title Anticipated publication date
3D printed joint replacement 0
Accident and emergency departments 20150501
Acute coronary syndrome - rivaroxaban 20150301
Acute coronary syndromes (including myocardial infarction) 20140901
Acute kidney injury 20141001
Alcohol dependence - nalmefene 20141101
Alcohol: preventing harmful alcohol use in the community 20141201
Anaemia (cancer-treatment induced) - erythropoiesis-stimulating agents (epoetin and darbepoetin) (inc rev TA142) 20140801
Ankylosing spondylitis and axial spondyloarthritis (non-radiographic) - adalimumab, etanercept infliximab and golimumab (inc rev TA143 and TA233) 20150101
Antibiotics for neonatal infection 20141201
Antimicrobial resistance - changing risk-related behaviours 20160301
Antimicrobial stewardship 20150301
Arterial reconstruction for locally advanced pancreatic cancer 0
Arthritis (juvenile idiopathic) - abatacept, adalimumab, etanercept and tocilizumab (inc review TA35) 20160201
Assessing motility of the gastrointestinal tract using a wireless capsule 0
Atrial fibrillation - clopidogrel (in combination with aspirin) 1
Atrial fibrillation - idraparinux sodium 1
Atrial fibrillation - vernakalant 1
Atrial fibrillation - ximelagatran 1
Atypical haemolytic uraemic syndrome (aHUS) - eculizumab 20140701
Autologous unmanipulated peripheral blood stem cell therapy for multiple sclerosis 0
Baroreflex activation therapy for resistant hypertension 0
Bioabsorbable artificial articular cartilage scaffold for cartilage repair 0
Bipolar disorder in adults 20150601
Bone loss (therapy-induced) in non-metastatic breast cancer - denosumab 1
Bone metastases (hormone refractory prostate cancer) - denosumab 1
Bradycardia - dual chamber pacemakers (review of TA88) 20150201
Breast cancer - intensity modulated radiotherapy 1
Breast cancer (advanced and/or metastatic) - sunitinib (in combination with capecitabine) 1
Breast cancer (advanced or metastatic) - lapatinib 1
Breast cancer (advanced or metastatic) hormone-sensitive - lapatinib 1
Breast cancer (early) - intrabeam radiotherapy system 20141101
Breast cancer (ErbB2 HER2, metastatic) - lapatinib (with paclitaxel, 1st line) 1
Breast cancer (first line treatment) - sunitinib (in combination with a taxane) 1
Breast cancer (HER2 negative, metastatic) - bevacizumab (2nd line) 1
Breast cancer (HER2 positive, metastatic) - pertuzumab (with trastuzumab and docetaxel) 1
Breast cancer (HER2 positive, unresectable) - trastuzumab emtansine (after trastuzumab and taxane) 1
Breast cancer (locally advanced or metastatic) - ixabepilone 1
Breast cancer (metastatic) -trastuzumab (as monotherapy and in combination with a taxane) 20111001
British hernia centre open tension-free repairs 0
Cardiac transplantation (rejection) - everolimus 1
Cell salvage/ ultrafiltraiton 0
Cervical ripening ballon for the induction of labour in women who have previously undergone cesarean section 0
Child abuse and neglect 20160401
Chronic iron overload (in people with thalassaemia) - desferrioxamine, deferiprone and deferasirox 1
Clinically isolated syndrome - beta interferons and glatiramer acetate 1
Clinitek Microalbumin 9 reagent strips for the early detection and monitoring of kidney disease 1
Clostridium difficile associated diarrhoea - tolevamer 1
Colon cancer (adjuvant) - irinotecan 1
Colorectal cancer (metastatic) - cetuximab (review TA176) and panitumumab (part review TA240) (1st line) 20160401
Colorectal cancer (metastatic) - regorafenib 1
Combined endoscopic and laparoscopic removal of colonic polyps 0
Community engagement (update) 20160101
Cone Beam CT 0
Constipation (opioid induced) - lubiprostone 20141001
Constipation (opioid-induced) - naloxegol 20150701
Coronary heart disease - cangrelor 20150801
Coronary venous arterialisation in patients with refractory angina 0
Crohn's disease (moderate to severe) - vedolizumab 20150601
Cutting blocks for total knee arthroplasty 0
Cyanoacrylate embolisation of refluxing great saphenous veins for varicose veins 0
DAP21 Diagnosis and monitoring of sepsis: procalcitonin testing (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay) 20150801
Deep vein thrombosis, pulmonary embolism - dabigatran etexilate (treatment, prevention) 20141001
Degradable surgical implant 0
Delirium 20140701
Dementia (non-Alzheimer) - new pharmaceutical treatments 1
Detecting, managing and monitoring haemostasis: viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems). 20140801
Diabetes - buccal insulin 1
Diabetes (type 2) - canagliflozin, dapagliflozin and empagliflozin (monotherapy) 20160101
Diabetes (type 2) - empagliflozin 20141201
Diabetic foot ulcers - new treatments 1
Diabetic retinopathy - ruboxistaurin 1
Diagnosis and monitoring of prostate cancer: PROGENSA PCA3 assay and the Prostate Health Index (PHI) 20150401
Diagnosis of skin cancer: The VivaScope imaging system (and other alternative technologies identified in scoping) 20151101
Disability, dementia and frailty in later life - mid-life approaches to prevention 20150201
Dry eye disease - ciclosporin 20150801
Dual Diagnosis 20160901
Dupuytren's contracture - collagenase clostridium histolyticum 20150101
Eating disorders 1
Ectopic pregnancy and miscarriage 20140701
Electrochemotherapy for the treatment of malignant melanoma 20130321
Ex utero intrapartum therapy for fetal obstruction 0
Excess winter deaths and illnesses 20150201
Exercise referral schemes 20140901
External Trigeminal Nerve Stimulation (eTNS) system for depression 0
External Trigeminal Nerve Stimulation (ETNS) system for epilepsy 0
Extra corporeal membrane oxygenation for acute heart failure in children 0
Falls 20150201
Falls - faller's clinics 1
Fertility problems 20141001
Flexible endoscopic treatment of pharyngeal pouch 0
Fluorouracil plasma monitoring: the My5-FU assay for guiding dose adjustment in patients receiving fluorouracil chemotherapy by continuous infusion 20150101
Fully implantable bone conducting hearing aid 0
Gastrointestinal stromal tumours - imatinib (adjuvant) (rev TA196) 20141001
Gastrointestinal stromal tumours (unresectable, metastatic) - masitinib (after progression with imatinib) 1
Gaucher disease (type 1) - eliglustat 20150501
Generalised anxiety disorder - quetiapine 1
Glaucoma - lerdelimumab (CAT-152) 1
Glioblastoma - bevacizumab 1
Head and neck cancer - contusugene ladenovec 1
Head and neck cancer - intensity modulated radiotherapy 1
Head injury 20141001
Heart failure (acute decompensated) - nesiritide 1
Heart failure (acute) - serelaxin 1
Hepatic encephalopathy - rifaximin (maintenance) 1
Hepatitis B 20140701
Hepatitis B (adults) - entecavir and tenofovir disoproxil fumarate 1
Hepatitis C (chronic) - simeprevir 20150101
Hepatitis C (chronic) - sofosbuvir 20141001
Hepatitis C (genotype 1, chronic) - faldaprevir 20150201
Home care 20150701
Hypercholesterolaemia - ezetimibe (review TA132) 20160501
Hypercholesterolemia - mipomersen 1
Idiopathic pulmonary fibrosis 20150101
Implantation of a duodenal-jejunal bypass sleeve for the management of type 2 diabetes 0
Implementing Vitamin D guidance 20141101
Inflammatory bowel disease 20140901
Insertion of a Leadless Pacemaker device for Cardiac Arithmia 0
Insertion of an annular disc implant at lumbar discectomy 20141101
Insertion of endobronchial nitinol coils to improve lung function in emphysema 0
Insertion of metal implants for the correction of prominent ears 0
Intra-coronary irradiation for prevention of stent thrombosis 0
Intravenous fluid therapy in adults in hospital 20140801
Itile implantation 0
Juvenile idiopathic arthritis - abatacept 1
Juvenile idiopathic arthritis - adalimumab 1
Kidney disease (autosomnal dominant polycystic) - tolvaptan 20150801
Kidney transplantation (rejection) - belatacept 1
Kidney transplantation (rejection) - everolimus 1
Knee cartilage defects - autologous chondrocyte implantation 20150701
KRAS mutation testing of tumours in adults with metastatic colorectal cancer 1
LARS ligament augmentation and reconstruction system for intra and extra-articulr reconstruction of ruptured ligaments, tendons and large muscle defects 0
Leukaemia (acute lymphoblastic) - dasatinib 1
Leukaemia (chronic lymphocytic) - obinutuzumab (with chlorambucil, 1st line) 20150201
Leukaemia (chronic lymphocytic, previously untreated) - ofatumumab 20150401
Leukaemia (chronic myeloid) - nilotinib (discontinued) 20110501
Levitronix CentriMag for treatment of refractory cardiogenic shock or severe cardiopulmonary insufficiency in adult and paediatric patients 1
Limb lengthening using Precise nail intramedullary motorised nail by external electromagnets 0
Low Density Lipoprotein Apheresis for Familial Hypercholesterolemia 0
Lung cancer (non-small cell) - afatinib 1
Lung cancer (non-small cell) - erlotinib and gefitinib (post chemotherapy) (rev TA162, TA175) 1
Lung cancer (non-small cell) - nintedanib 20150401
Lung cancer (non-small-cell) - cetuximab 1
Lung cancer (non-small-cell, advanced or metastatic maintenance treatment) - erlotinib (in combination with bevacizumab) 1
Lung cancer (non-small-cell, advanced or metastatic second line) - erlotinib (in combination with bevacizumab) 1
Lung cancer (non-small-cell, second line treatment) - vandetanib 1
Lung transplantation with ex-vivo perfusion 20130921
LVAD Destination Therapy 0
Lymphoma (follicular non Hodgkin's - advanced) - bortezomib 1
Lymphoma (Hodgkin's, CD30-positive) - brentuximab vedotin (after autologous stem cell transplant) 20160101
Lymphoma (mantle cell) - bendamustine (1st line, with rituximab) 1
Lymphoma (non Hodgkin's) - bendamustine (with rituximab) 1
Lymphoma (non Hodgkin's, peripheral T-cell) - pralatrexate 1
Macular oedema (diabetic) - dexamethasone intravitreal implant 20150401
Macular oedema (diabetic) - pegaptanib sodium 1
Maintaining a healthy weight and preventing excess weight gain among children and adults 20150201
Major depressive disorder - vortioxetine 20150901
Managing blood glucose levels in people with Diabetes Mellitus: The MiniMed Paradigm Veo System (and other alternative technologies identified in scoping) 20151001
Managing medicines in care homes 20150301
Melanoma (advanced and metastatic) - temozolomide 1
Melanoma (BRAF V600, unresectable, metastatic) - dabrafenib 20141201
Melanoma (BRAF V600E mutation positive, unresectable, metastatic) - dabrafenib and trametinib 1
Melanoma (metastatic) - paclitaxel albumin-bound nanoparticles (1st line) 1
Minimally Invasive Closure Of Enterocutaneous Fistula 0
Minimally invasive video-assisted parathyroidectomy 0
Minimally invasive video-assisted thyroidectomy 0
MRI guided focussed ultrasound for chronic pain 0
Multimorbidities: system integration to meet population needs 1
Multiple myeloma - bortezomib (consolidation therapy) 1
Multiple myeloma - lenalidomide (maintenance, post autologous stem cell transplantation) 1
Multiple myeloma - lenalidomide (post bortezomib) (part rev TA171) 20140901
Multiple myeloma (newly diagnosed) - lenalidomide 1
Multiple myeloma (one prior therapy) - vorinostat (with bortezomib) 1
Multiple myeloma (relapsed, refractory) - pomalidomide 20150201
Multiple sclerosis - cladribine 1
Multiple sclerosis - sativex 1
Multiple sclerosis (primary-progressive) - fingolimod 1
Multiple sclerosis (relapsing-remitting) - dimethyl fumarate 20140801
Multiple sclerosis (relapsing-remitting) - laquinimod 1
Myelodysplastic syndrome (deletion 5q) - lenalidomide 1
Myocardial infarction (acute) - Early rule out using high-sensitivity troponin tests (Elecsys Troponin T high-sensitive, ARCHITECT STAT High Sensitive Troponin-I and AccuTnI+3 assays 20141001
Nocturnal enuresis in children and young people 20140901
Obesity - lorcaserin 1
Obesity - phentermine (with topiramate) 1
Obesity: prevention and lifestyle management in children 20141201
Older people: independence and mental wellbeing 20151101
open reduction of stable slipped capital femoral epiphysis 0
Oral health - in nursing and residential care 20160601
Oral health promotion approaches for dental teams 20151001
Oral health: local authority oral health improvement strategies 20141001
OraQuick and reg; HCV Rapid Antibody Test - not proceeding 1
Organ rejection (liver transplantation, prevention) - everolimus 20150401
Osteoarthritis 20150501
Osteoarthritis - diacerein 1
Osteoarthritis - naproxcinod 1
Osteoarthritis and rheumatoid arthritis - cox-II inhibitors (review) 1
Osteoporosis (prevention) - bisphosphonates (inc part rev TA160, TA161) 20151101
Ovarian (epithelial), fallopian and peritoneal cancer - pazopanib (maintenance) 1
Ovarian cancer - topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for advanced recurrent disease only (Review of TA 91 and TA 222) 1
Ovarian cancer - vintafolide (with pegylated liposomal doxorubicin) 1
Pancreatic adenocarcinoma (untreated, metastatic) - paclitaxel albumin-bound nanoparticles (with gemcitabine) 20150101
Pancreatic cancer - capectitabine 1
Pancreatic cancer (locally advanced, metastatic) - masitinib 1
Pancreatic cancer (metastatic) - nimotuzumab (1st line) 20150801
Parafricta bootees and undergarments to reduce skin breakdown in people with frail skin or at risk of pressure ulcers 20141101
Percutaneous pulmonary valve implantation for right ventricular outflow tract dysfunction 20131221
Percutaneous repair of an aortic paraprosthetic leak 0
Peroral endoscopic myotomy (POEM) for achalasia 0
Personality disorders (borderline and antisocial) 21000101
Physical activity: encouraging activity in all people in contact with the NHS (staff, patients and carers) 20150101
Pressure ulcers 0
Prostate cancer 20150601
Prostate cancer - intensity modulated radiotherapy 1
Prostate cancer (advanced, hormone dependent) - degarelix depot 20140501
Prostate cancer (hormone refractory) - atrasentan 1
Prostate cancer (hormone relapsed, bone metastases) - radium-223 dichloride 20140901
Prostate cancer (metastatic, hormone relapsed) - sipuleucel-T (1st line) 20150201
Prostate cancer (metastatic, hormone relapsed, not treated with chemotherapy) - abiraterone acetate (with prednisolone) 1
Prostate cancer (metastatic, hormone-relapsed) - enzalutamide 20150501
Prostate cancer (prevention) - dutasteride 1
Psoriasis - briakinumab (suspended) 1
Psoriasis (plaque, moderate to severe) - apremilast 20150801
Psoriasis (plaque, moderate to severe) - secukinumab 20150701
Psoriatic arthritis (active) - apremilast (post DMARDs) 20150801
Psoriatic arthritis (moderate to severe) - leflunomide 1
Pulmonary arterial hypertension (adults) - drugs 1
Renal cell carcinoma (advanced) - axitinib 1
Renal cell carcinoma (second line metastatic) - pazopanib 20110101
Renal replacement therapy services 20141101
Renal transplantation (adults) - immunosuppressive therapy (including Review of TA 85) 20150801
Renal transplantation (children, adolescents) - immunosuppressive regimens (review of TA99) 20151001
Replacement of the distal radio-ulnar joint with Scheker Distal Radio-Ulnar Joint Prosthesis for Inpatients Having Undergone Resection of the DRUJ 0
Rheumatoid arthritis - adalimumab, etanercept and infliximab (sequential use) 1
Rheumatoid arthritis - adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, abatacept and tocilizumab - review 1
Rheumatoid arthritis - tofacitinib 1
Rheumatoid arthritis (after the failure of conventional DMARDs) -rituximab 1
Safe Midwifery Staffing for Maternity Settings 20150101
Safe nurse staffing of adult wards in acute hospitals 20140701
Safety and 6 month effectiveness of minimally invasive SI joint fusion for back pain 0
Sarcoma 20150101
Schizophrenia in adults 20150201
School based interventions to prevent smoking (partial update) 1
Self-monitoring coagulation status in people on long-term vitamin K antagonist therapy who have atrial fibrillation or heart valve disease: point-of-care coagulometers (the CoaguChek XS system and the INRatio2 PT/INR monitor) 20140901
Sexually harmful behaviour among young people 20160801
SherLock 3CG Tip Confirmation System for placement of peripherally inserted central catheters 20150301
Shock or load absorber for arthritis surgery of the knee 0
SILK artery reconstruction device 1
Smoking - reducing tobacco use in the community 20150101
Smoking cessation (update) 1
Social and emotional wellbeing in primary and secondary education (update) 1
Social care of older people with multiple long-term conditions 20150901
Soft tissue or bone sarcoma (metastatic) - ridaforolimus (maintenance) 1
Spineform Hemibridge endoscopic vertebral stapling to reduce curvature in the growing scoliotic spine in children 0
Sunlight exposure - benefits and risks 20150701
Systemic lupus erythematosus - prasterone 0
Systemic lupus erythematosus (autoantibody-positive) - belimumab 1
T-cell lymphoma (peripheral, relapsed or refractory) - romidepsin 1
Telemetric adjustable pulmonary artery banding for reducing pulmonary hypertension in infants with congenital heart defects 0
The ReCell Spray-On Skin system for treating skin loss, scarring and depigmentation after burn injury 20140901
The safe use and management of controlled drugs 20151201
The TURis system for transurethral resection of the prostate 20150101
Thrombophilia 1
Transanal minimally invasive proctectomy 0
Transarterial Chemoembolisation using drug eluting beads for hepato cellular carcinoma 0
Transcatheter valve-in-valve implantation for the treatment of aortic bioprosthetic valve dysfunction 0
Transcatheter valve-in-valve implantation for the treatment of mitral valve 0
Transcutaneous cranial electrical stimulation for insomnia, depression or anxiety 0
Transient loss of consciousness 20141001
Transition between inpatient hospital settings and community or care home settings for adults with social care needs 20151101
Transition between inpatient mental health settings and community and care home settings for people with social care needs 20160801
Transition from children's to adult services 20160201
Transperineal insertion of a balloon system for prostate cancer radiotherapy 0
Transvaginal electrical stimulation treating stress urinary incontinence in women 0
Tuberculosis (update) 20151001
Ulcerative colitis (moderate to severely active) - vedolizumab 20150401
Ulcerative colitis (moderate, severe) - infliximab (review TA140), adalimumab (review TA262) and golimumab (2nd line) 20150101
Urinary incontinence in women 20150101
Urinary tract infection in adults 20150501
Urticaria (chronic spontaneous, previously treated) - omalizumab 20150401
US guided injection of local anesthetic for pain management in breast surgery 0
Varicose veins in the legs 20140801
Venous leg ulcers - new treatments 0
Venous thromboembolism - apixaban (acute medical illness) 1
Venous thromboembolism (prevention) - rivaroxaban 1
Venous thromboembolism (recurrent) - idraparinux sodium 1
Venous thromboembolism (VTE) - ximelagatran 1
VibraTip for testing vibration perception to detect diabetic peripheral neuropathy 20141201
Virtual Touch Quantification to diagnose and monitor liver fibrosis 20150201
Workplace health - employees with chronic diseases and long-term conditions 1
Workplace health - older employees 20160101
Workplace policy and management practices to improve the health and wellbeing of employees 20150501
Xpert MTB/RIF assay (and alternative technologies identified during scoping) 0

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