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Guidance (217)
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Highly specialised technologies guidance (7)
Interventional procedures guidance (2)
Technology appraisal guidance (208)
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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
Dersimelagon for
treating
erythropoietic protoporphyria and X-linked protoporphyria in people 12 years and over [ID6160]
Technology appraisal guidance
TBC
Deuruxolitinib for
treating
severe alopecia areata ID6597
Technology appraisal guidance
8 October 2026
Deutetrabenazine for
treating
tardive dyskinesia ID6550
Technology appraisal guidance
TBC
Dexmedetomidine for
treating
agitation associated with bipolar disorder in people 18 to 75 years [TS ID 10725]
Technology appraisal guidance
TBC
Dexmedetomidine for
treating
agitation associated with schizophrenia TS ID 10726
Technology appraisal guidance
TBC
Donanemab for
treating
mild cognitive impairment or mild dementia caused by Alzheimer's disease [ID6222]
Technology appraisal guidance
TBC
Doxecitine–doxribtimine for
treating
thymidine kinase 2 deficiency in people of any age [ID6484]
Highly specialised technology
TBC
Dupilumab for
treating
bullous pemphigoid [ID6479]
Technology appraisal guidance
TBC
Dupilumab for
treating
chronic spontaneous urticaria in people 12 years and over [ID4055]
Technology appraisal guidance
TBC
Dupilumab for
treating
severe chronic rhinosinusitis with nasal polyps (review of TA648) [ID6480]
Technology appraisal guidance
TBC
Durvalumab with gemcitabine and cisplatin before surgery (neoadjuvant) then alone after surgery (adjuvant) for
treating
muscle-invasive bladder cancer [ID6168]
Technology appraisal guidance
TBC
Durvalumab with platinum-based chemotherapy, then with or without olaparib, for
treating
newly diagnosed advanced or recurrent endometrial cancer ID6317
Technology appraisal guidance
TBC
Durvalumab with radiotherapy for
treating
unresected node-negative stage 1 or 2 non-small-cell lung cancer [ID6567]
Technology appraisal guidance
14 April 2027
Durvalumab with tremelimumab and chemotherapy for
treating
unresectable or advanced urothelial cancer [ID3855]
Technology appraisal guidance
TBC
Durvalumab with tremelimumab for
treating
limited-stage small-cell lung cancer after chemoradiation [ID5097]
Technology appraisal guidance
TBC
Efgartigimod with recombinant human hyaluronidase PH20 for
treating
chronic inflammatory demyelinating polyneuropathy [ID6409]
Technology appraisal guidance
29 July 2026
Eflornithine for
treating
high-risk neuroblastoma with complete or partial response after immunotherapy [ID4060]
Technology appraisal guidance
TBC
Elexacaftor–tezacaftor–ivacaftor with ivacaftor for
treating
cystic fibrosis without an F508del mutation and with a mutation in the CFTR gene that is responsive to elexacaftor–tezacaftor–ivacaftor in people aged 6 and over [TSID11847]
Technology appraisal guidance
TBC
Encorafenib with binimetinib for
treating
BRAF V600E mutation-positive advanced non-small-cell lung cancer [ID6177]
Technology appraisal guidance
TBC
Endoscopic bipolar radiofrequency ablation for
treating
biliary obstruction caused by cholangiocarcinoma or pancreatic adenocarcinoma
Interventional procedures guidance
TBC
Eneboparatide for
treating
chronic hypoparathyroidism [ID6532]
Technology appraisal guidance
TBC
Enfortumab vedotin for
treating
locally advanced or metastatic urothelial cancer after 2 therapies [ID3845]
Technology appraisal guidance
15 June 2022
Ensitrelvir for
treating
COVID 19 [ID6231]
Technology appraisal guidance
TBC
Epcoritamab for
treating
relapsed or refractory diffuse large B-cell lymphoma after first-line systemic treatment [ID6463]
Technology appraisal guidance
TBC
Epcoritamab for
treating
relapsed or refractory follicular lymphoma after 2 or more systemic treatments [ID6338]
Technology appraisal guidance
25 February 2026
Epcoritamab with rituximab and lenalidomide for
treating
relapsed or refractory follicular lymphoma after 1 or more systemic treatments [ID6586]
Technology appraisal guidance
3 September 2026
ERC1671 for
treating
progressed or recurrent grade IV glioma (glioblastoma or gliosarcoma) [ID1623]
Technology appraisal guidance
TBC
Etripamil for
treating
paroxysmal supraventricular tachycardia [ID6581]
Technology appraisal guidance
TBC
Favezelimab–pembrolizumab for
treating
relapsed or refractory classical Hodgkin lymphoma after anti-PD-L1 treatment [ID6393]
Technology appraisal guidance
TBC
Fezolinetant for
treating
vasomotor symptoms associated with the menopause [ID5071]
Technology appraisal guidance
TBC
Fidanacogene elaparvovec for
treating
moderately severe to severe haemophilia B [ID4032]
Technology appraisal guidance
TBC
Filgotinib for
treating
axial spondyloarthritis ID6594
Technology appraisal guidance
TBC
Finerenone for
treating
heart failure with preserved or mildly reduced ejection fraction [ID6514]
Technology appraisal guidance
4 June 2026
Fordadistrogene movaparvovec for
treating
Duchenne muscular dystrophy [ID6133]
Technology appraisal guidance
TBC
Gefurulimab for
treating
antibody-positive generalised myasthenia gravis [TSID12256]
Technology appraisal guidance
TBC
Giredestrant with everolimus for
treating
oestrogen-receptor positive HER2-negative advanced breast cancer after cyclin-dependent kinase 4 and 6 inhibitor and endocrine treatment ID6576
Technology appraisal guidance
TBC
Giroctocogene fitelparvovec for
treating
moderately severe to severe haemophilia A ID6312
Technology appraisal guidance
TBC
Givinostat for
treating
Duchenne muscular dystrophy in people 6 years and over [ID6323]
Technology appraisal guidance
TBC
Glycopyrronium bromide cream for
treating
severe primary axillary hyperhidrosis [ID6487]
Technology appraisal guidance
11 March 2026
Govorestat for
treating
classic galactosemia in people 2 to 65 years [TSID12071]
Technology appraisal guidance
TBC
Hydromethylthionine mesylate for
treating
mild cognitive impairment or mild or moderate dementia caused by Alzheimer's disease [ID6343]
Technology appraisal guidance
TBC
Ianalumab for
treating
active Sjogren's syndrome [ID6634]
Technology appraisal guidance
TBC
Ibrutinib for
treating
relapsed or refractory follicular lymphoma [1251]
Technology appraisal guidance
TBC
Iclepertin for
treating
cognitive impairment associated with schizophrenia [ID6483]
Technology appraisal guidance
TBC
Icotrokinra for
treating
moderate to severe plaque psoriasis in people 12 years and over ID6579
Technology appraisal guidance
TBC
ID6610 Cemiplimab for
treating
recurrent or metastatic cervical cancer that has progressed on or after platinum-based chemotherapy (review of TA901)
Technology appraisal guidance
3 September 2026
Imetelstat for
treating
relapsed or refractory transfusion-dependent myelodysplastic syndromes [ID3922]
Technology appraisal guidance
TBC
Imlunestrant for
treating
oestrogen receptor-positive HER2-negative advanced breast cancer after endocrine therapy [ID6373]
Technology appraisal guidance
TBC
Inavolisib with fulvestrant for
treating
recurrent hormone receptor-positive HER2-negative PIK3CA-mutated locally advanced or metastatic breast cancer after a CDK 4-6 inhibitor [ID6650]
Technology appraisal guidance
TBC
Inavolisib with palbociclib and fulvestrant for
treating
recurrent hormone receptor-positive HER2-negative PIK3CA-positive advanced breast cancer after adjuvant endocrine treatment [ID6425]
Technology appraisal guidance
12 June 2026
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