Published Guidance, NICE advice and quality standards

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TitleReference numberPublishedLast updated
Sinusitis (acute): antimicrobial prescribingNG79
Cataracts in adults: managementNG77
Cystic fibrosis: diagnosis and managementNG78
Hepatitis B (chronic): diagnosis and managementCG165
Tofacitinib for moderate to severe rheumatoid arthritisTA480
Immunosuppressive therapy for kidney transplant in adultsTA481
Immunosuppressive therapy for kidney transplant in children and young peopleTA482
Child maltreatment: when to suspect maltreatment in under 18sCG89
Child abuse and neglectNG76
Autologous chondrocyte implantation for treating symptomatic articular cartilage defects of the kneeTA477
Brentuximab vedotin for treating relapsed or refractory systemic anaplastic large cell lymphomaTA478
Reslizumab for treating severe eosinophilic asthmaTA479
Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure caused by motor neurone diseaseIPG593
Faltering growth: recognition and management of faltering growth in childrenNG75
Cetuximab and panitumumab for previously untreated metastatic colorectal cancerTA439
Intermediate care including reablementNG74
Ab externo canaloplasty for primary open-angle glaucomaIPG591
High-intensity focused ultrasound for symptomatic breast fibroadenomaIPG592
Pembrolizumab for advanced melanoma not previously treated with ipilimumabTA366
Pembrolizumab for treating PD-L1-positive non-small-cell lung cancer after chemotherapyTA428
Pembrolizumab for treating advanced melanoma after disease progression with ipilimumabTA357
Fertility problems: assessment and treatmentCG156
Sorafenib for treating advanced hepatocellular carcinomaTA474
Dimethyl fumarate for treating moderate to severe plaque psoriasisTA475
Paclitaxel as albumin-bound nanoparticles with gemcitabine for untreated metastatic pancreatic cancerTA476
Psoriasis: assessment and managementCG153
Cetuximab for treating recurrent or metastatic squamous cell cancer of the head and neckTA473
Vitamin D: supplement use in specific population groupsPH56
Radiofrequency treatment for haemorrhoidsIPG589
Methylnaltrexone bromide for treating opioid-induced constipation (terminated appraisal)TA468
Idelalisib with ofatumumab for treating chronic lymphocytic leukaemia (terminated appraisal)TA469
Advanced breast cancer: diagnosis and treatmentCG81
Holoclar for treating limbal stem cell deficiency after eye burnsTA467
Pemetrexed for the maintenance treatment of non-small-cell lung cancerTA190
Developmental follow-up of children and young people born pretermNG72
Cabozantinib for previously treated advanced renal cell carcinomaTA463
Baricitinib for moderate to severe rheumatoid arthritisTA466
moorLDI2-BI: a laser doppler blood flow imager for burn wound assessmentMTG2
Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutritionCG32
Transcatheter aortic valve implantation for aortic stenosisIPG586
Adalimumab and dexamethasone for treating non-infectious uveitisTA460
Roflumilast for treating chronic obstructive pulmonary diseaseTA461
Nivolumab for treating relapsed or refractory classical Hodgkin lymphomaTA462
Parkinson's disease in adultsNG71
Constipation in children and young people: diagnosis and managementCG99
Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young peopleTA455
Ustekinumab for moderately to severely active Crohn's disease after previous treatmentTA456
New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scannersDG3
Ibrutinib for untreated chronic lymphocytic leukaemia without a 17p deletion or TP53 mutation (terminated appraisal)TA452
Bortezomib for treating multiple myeloma after second or subsequent relapse (terminated appraisal)TA453
Daratumumab with lenalidomide and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal)TA454
Eliglustat for treating type 1 Gaucher diseaseHST5
Infracoccygeal sacropexy using mesh to repair vaginal vault prolapseIPG581
Infracoccygeal sacropexy using mesh to repair uterine prolapseIPG582
Sacrocolpopexy using mesh to repair vaginal vault prolapseIPG583
Uterine suspension using mesh (including sacrohysteropexy) to repair uterine prolapseIPG584
Etelcalcetide for treating secondary hyperparathyroidismTA448
Everolimus and sunitinib for treating unresectable or metastatic neuroendocrine tumours in people with progressive diseaseTA449
Blinatumomab for previously treated Philadelphia-chromosome-negative acute lymphoblastic leukaemiaTA450
Ponatinib for treating chronic myeloid leukaemia and acute lymphoblastic leukaemiaTA451
Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysisDG29
Spondyloarthritis in over 16s: diagnosis and managementNG65
Endoscopic full thickness removal of non-lifting colonic polypsIPG580
Afatinib for treating advanced squamous non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal)TA444
Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDsTA445
Idiopathic pulmonary fibrosis in adults: diagnosis and managementCG163
Virtual chromoendoscopy to assess colorectal polyps during colonoscopyDG28
Intravenous fluid therapy in adults in hospitalCG174
Irreversible electroporation for treating pancreatic cancerIPG579
Pegylated liposomal irinotecan for treating pancreatic cancer after gemcitabineTA440
Ixekizumab for treating moderate to severe plaque psoriasisTA442
Obeticholic acid for treating primary biliary cholangitisTA443
Antisocial behaviour and conduct disorders in children and young people: recognition and managementCG158
Alcohol-use disorders: diagnosis and management of physical complicationsCG100
Minimally invasive sacroiliac joint fusion surgery for chronic sacroiliac painIPG578
Irritable bowel syndrome in adults: diagnosis and managementCG61
Managing medicines for adults receiving social care in the communityNG67
Panitumumab in combination with chemotherapy for the treatment of metastatic colorectal cancer (terminated appraisal)TA240
Alectinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer (terminated appraisal)TA438
Patient group directionsMPG2
Extraurethral (non-circumferential) retropubic adjustable compression devices for stress urinary incontinence in womenIPG576
Sacrocolpopexy with hysterectomy using mesh to repair uterine prolapseIPG577
Bevacizumab for treating EGFR mutation-positive non-small-cell lung cancer (terminated appraisal)TA436
Ibrutinib with bendamustine and rituximab for treating relapsed or refractory chronic lymphocytic leukaemia after systemic therapy (terminated appraisal)TA437
Elotuzumab for previously treated multiple myeloma (terminated appraisal)TA434
Tenofovir alafenamide for treating chronic hepatitis B (terminated appraisal)TA435
Mental health of adults in contact with the criminal justice systemNG66
Ustekinumab for treating active psoriatic arthritisTA340
Ustekinumab for the treatment of adults with moderate to severe psoriasisTA180
Molecular testing strategies for Lynch syndrome in people with colorectal cancerDG27
Migalastat for treating Fabry diseaseHST4
Lateral interbody fusion in the lumbar spine for low back painIPG574
Trabecular stent bypass microsurgery for open-angle glaucomaIPG575
Everolimus for advanced renal cell carcinoma after previous treatmentTA432
Apremilast for treating active psoriatic arthritisTA433
Healthcare-associated infections: prevention and control in primary and community careCG139
HumiGard for preventing inadvertent perioperative hypothermiaMTG31
Osteoporosis: assessing the risk of fragility fractureCG146
Cerebral palsy in under 25s: assessment and managementNG62
Ibrutinib for previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia with 17p deletion or TP53 mutationTA429
Sofosbuvir–velpatasvir for treating chronic hepatitis CTA430
Pomalidomide for multiple myeloma previously treated with lenalidomide and bortezomibTA427
Organ donation for transplantation: improving donor identification and consent rates for deceased organ donationCG135
Extracorporeal shockwave therapy for Achilles tendinopathyIPG571
Radiation therapy for early Dupuytren's diseaseIPG573
Everolimus with exemestane for treating advanced breast cancer after endocrine therapyTA421
Crizotinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancerTA422
Eribulin for treating locally advanced or metastatic breast cancer after 2 or more chemotherapy regimensTA423
Pertuzumab for the neoadjuvant treatment of HER2-positive breast cancerTA424
Dasatinib, nilotinib and high-dose imatinib for treating imatinib-resistant or intolerant chronic myeloid leukaemiaTA425
Dasatinib, nilotinib and imatinib for untreated chronic myeloid leukaemiaTA426
Hypothermia: prevention and management in adults having surgeryCG65
Epiduroscopic lumbar discectomy through the sacral hiatus for sciaticaIPG570
Ticagrelor for preventing atherothrombotic events after myocardial infarctionTA420
XprESS multi sinus dilation system for treating chronic sinusitisMTG30
Recent-onset chest pain of suspected cardiac origin: assessment and diagnosisCG95
Coexisting severe mental illness and substance misuse: community health and social care servicesNG58
Spasticity in under 19s: managementCG145
Endoscopic transluminal pancreatic necrosectomyIPG567
Percutaneous insertion of craniocaudal expandable implants for vertebral compression fractureIPG568
Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy for treating morbid obesityIPG569
Dapagliflozin in combination therapy for treating type 2 diabetesTA288
Nivolumab for previously treated advanced renal cell carcinomaTA417
Dapagliflozin in triple therapy for treating type 2 diabetesTA418
Apremilast for treating moderate to severe plaque psoriasisTA419
High-throughput non-invasive prenatal testing for fetal RHD genotypeDG25
Physical health of people in prisonNG57
Psychosis and schizophrenia in children and young people: recognition and managementCG155
Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitorTA415
Elbasvir–grazoprevir for treating chronic hepatitis CTA413
Cobimetinib in combination with vemurafenib for treating unresectable or metastatic BRAF V600 mutation-positive melanomaTA414
Single-incision short sling mesh insertion for stress urinary incontinence in womenIPG566
Miniature lens system implantation for advanced age-related macular degenerationIPG565
Necitumumab for untreated advanced or metastatic squamous non-small-cell lung cancerTA411
Radium-223 dichloride for treating hormone-relapsed prostate cancer with bone metastasesTA412
Crizotinib for untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancerTA406
Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitorsTA407
Pegaspargase for treating acute lymphoblastic leukaemiaTA408
Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusionTA409
Talimogene laherparepvec for treating unresectable metastatic melanomaTA410
Multimorbidity: clinical assessment and managementNG56
Harmful sexual behaviour among children and young peopleNG55
Mental health problems in people with learning disabilities: prevention, assessment and managementNG54
Transition between inpatient mental health settings and community or care home settingsNG53
Stable angina: managementCG126
Acute upper gastrointestinal bleeding in over 16s: managementCG141
Bosutinib for previously treated chronic myeloid leukaemiaTA401
Pemetrexed maintenance treatment for non-squamous non-small-cell lung cancer after pemetrexed and cisplatinTA402
Ramucirumab for previously treated locally advanced or metastatic non-small-cell lung cancerTA403
Degarelix for treating advanced hormone-dependent prostate cancerTA404
Trifluridine–tipiracil for previously treated metastatic colorectal cancerTA405
Cabazitaxel for hormone-relapsed metastatic prostate cancer treated with docetaxelTA391
Palliative care for adults: strong opioids for pain reliefCG140
Percutaneous endoscopic laser balloon pulmonary vein isolation for atrial fibrillationIPG563
Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimenTA259
Lumacaftor–ivacaftor for treating cystic fibrosis homozygous for the F508del mutationTA398
Azacitidine for treating acute myeloid leukaemia with more than 30% bone marrow blastsTA399
Nivolumab in combination with ipilimumab for treating advanced melanomaTA400
Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicatedTA387
Non-Hodgkin's lymphoma: diagnosis and managementNG52
Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional proceduresCG64
Non-alcoholic fatty liver disease (NAFLD): assessment and managementNG49
Oral health for adults in care homesNG48
Microstructural scaffold (patch) insertion without autologous cell implantation for repairing symptomatic chondral knee defectsIPG560
Transcervical extracorporeal reverse flow neuroprotection for reducing the risk of stroke during carotid artery stentingIPG561
Ultrasound-guided percutaneous radiofrequency ablation for benign thyroid nodulesIPG562
Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemiaTA393
Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemiaTA394
Ceritinib for previously treated anaplastic lymphoma kinase positive non-small-cell lung cancerTA395
Trametinib in combination with dabrafenib for treating unresectable or metastatic melanomaTA396
Adalimumab for treating moderate to severe hidradenitis suppurativaTA392
Endovenous mechanochemical ablation for varicose veinsIPG557
Haematological cancers: improving outcomesNG47
Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetesTA390
ImmunoCAP ISAC 112 for multiplex allergen testingDG24
Microwave ablation for treating liver metastasesIPG553
Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertensionIPG554
Percutaneous interlaminar endoscopic lumbar discectomy for sciaticaIPG555
Percutaneous transforaminal endoscopic lumbar discectomy for sciaticaIPG556
Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fractionTA388
Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancerTA389
Controlled drugs: safe use and managementNG46
Routine preoperative tests for elective surgeryNG45
Corticosteroid-eluting bioabsorbable stent or spacer insertion during endoscopic sinus surgery to treat chronic rhinosinusitisIPG551
Transcutaneous stimulation of the cervical branch of the vagus nerve for cluster headache and migraineIPG552
Endoscopic carbon dioxide laser cricopharyngeal myotomy for relief of oropharyngeal dysphagiaIPG550
Ruxolitinib for treating disease-related splenomegaly or symptoms in adults with myelofibrosisTA386
Community engagement: improving health and wellbeing and reducing health inequalitiesNG44
Guidance on the use of temozolomide for the treatment of recurrent malignant glioma (brain cancer)TA23
Spectra Optia for automatic red blood cell exchange in people with sickle cell diseaseMTG28
Angioplasty and stenting to treat peripheral arterial disease causing refractory erectile dysfunctionIPG546
Mechanical clot retrieval for treating acute ischaemic strokeIPG548
Normothermic extracorporeal preservation of hearts for transplantation following donation after brainstem deathIPG549
Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemiaTA385
Transition from children's to adults' services for young people using health or social care servicesNG43
Nivolumab for treating advanced (unresectable or metastatic) melanomaTA384
Therapeutic monitoring of TNF-alpha inhibitors in Crohn's disease (LISA-TRACKER ELISA kits, IDKmonitor ELISA kits, and Promonitor ELISA kits)DG22
Fractures (non-complex): assessment and managementNG38
Major trauma: assessment and initial managementNG39
Major trauma: service deliveryNG40
Spinal injury: assessment and initial managementNG41
Sunlight exposure: risks and benefitsNG34
TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritisTA383
Percutaneous coblation of the intervertebral disc for low back pain and sciaticaIPG543
Percutaneous electrothermal treatment of the intervertebral disc annulus for low back pain and sciaticaIPG544
Percutaneous intradiscal radiofrequency treatment of the intervertebral disc nucleus for low back painIPG545
Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicatedTA377
Ramucirumab for treating advanced gastric cancer or gastro–oesophageal junction adenocarcinoma previously treated with chemotherapyTA378
Nintedanib for treating idiopathic pulmonary fibrosisTA379
Panobinostat for treating multiple myeloma after at least 2 previous treatmentsTA380
Eltrombopag for treating severe aplastic anaemia refractory to immunosuppressive therapy (terminated appraisal)TA382
Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failedTA375
Guidance on the use of imatinib for chronic myeloid leukaemiaTA70
Older people: independence and mental wellbeingNG32
Repetitive transcranial magnetic stimulation for depressionIPG542
Joint distraction for ankle osteoarthritisIPG538
Radiofrequency ablation for symptomatic interdigital (Morton's) neuromaIPG539
Electrical stimulation of the lower oesophageal sphincter for treating gastro-oesophageal reflux diseaseIPG540
Insertion of a subretinal prosthesis system for retinitis pigmentosaIPG537
Care of dying adults in the last days of lifeNG31
Ciclosporin for treating dry eye disease that has not improved despite treatment with artificial tearsTA369
Bortezomib for previously untreated mantle cell lymphomaTA370
Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritisTA373
Erlotinib and gefitinib for treating non-small-cell lung cancer that has progressed after prior chemotherapyTA374
Transition between inpatient hospital settings and community or care home settings for adults with social care needsNG27
Implantation of a corneal graft–keratoprosthesis for severe corneal opacity in wet blinking eyesIPG534
Living-donor liver transplantationIPG535
Sacral nerve stimulation for idiopathic chronic non-obstructive urinary retentionIPG536
Children's attachment: attachment in children and young people who are adopted from care, in care or at high risk of going into careNG26
Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis CTA365
Vortioxetine for treating major depressive episodesTA367
Ledipasvir–sofosbuvir for treating chronic hepatitis CTA363
Blood transfusionNG24
VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesionsDG19
Older people with social care needs and multiple long-term conditionsNG22
Implanting a baroreceptor stimulation device for resistant hypertensionIPG533
Developing and updating local formulariesMPG1
Tolvaptan for treating autosomal dominant polycystic kidney diseaseTA358
Idelalisib for treating chronic lymphocytic leukaemiaTA359
Paclitaxel as albumin-bound nanoparticles with carboplatin for untreated non-small-cell lung cancer (terminated appraisal)TA362
Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay)DG18
Low energy contact X-ray brachytherapy (the Papillon technique) for early stage rectal cancerIPG532
Home care: delivering personal care and practical support to older people living in their own homesNG21
Coeliac disease: recognition, assessment and managementNG20
Preoperative high dose rate brachytherapy for rectal cancerIPG531
Transcranial direct current stimulation (tDCS) for depressionIPG530
Vedolizumab for treating moderately to severely active Crohn's disease after prior therapyTA352
Bevacizumab for treating relapsed, platinum‑resistant epithelial ovarian, fallopian tube or primary peritoneal cancer (terminated appraisal)TA353
Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolismTA354
Antimicrobial stewardship: systems and processes for effective antimicrobial medicine useNG15
Insertion of a double balloon catheter for induction of labour in pregnant women without previous caesarean sectionIPG528
Joint distraction for knee osteoarthritis without alignment correctionIPG529
Naloxegol for treating opioid‑induced constipationTA345
Aflibercept for treating diabetic macular oedemaTA346
Nintedanib for previously treated locally advanced, metastatic, or locally recurrent non‑small‑cell lung cancerTA347
Everolimus for preventing organ rejection in liver transplantationTA348
Secukinumab for treating moderate to severe plaque psoriasisTA350
Cangrelor for reducing atherothrombotic events in people undergoing percutaneous coronary intervention or awaiting surgery requiring interruption of anti‑platelet therapy (terminated appraisal)TA351
Suture fixation of acute disruption of the distal tibiofibular syndesmosisIPG521
Ultrasound‑enhanced, catheter‑directed thrombolysis for deep vein thrombosisIPG523
Ultrasound‑enhanced, catheter‑directed thrombolysis for pulmonary embolismIPG524
Electrotherapy for the treatment of haemorrhoidsIPG525
Implantation of a sphenopalatine ganglion stimulation device for chronic cluster headacheIPG527
Insertion of an epiretinal prosthesis for retinitis pigmentosaIPG519
Radiofrequency ablation for gastric antral vascular ectasiaIPG520
Omalizumab for previously treated chronic spontaneous urticariaTA339
Vedolizumab for treating moderately to severely active ulcerative colitisTA342
Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolismTA341
Lower urinary tract symptoms in men: managementCG97
Obinutuzumab in combination with chlorambucil for untreated chronic lymphocytic leukaemiaTA343
Challenging behaviour and learning disabilities: prevention and interventions for people with learning disabilities whose behaviour challengesNG11
Violence and aggression: short-term management in mental health, health and community settingsNG10
Insertion of a balloon device to disimpact an engaged fetal head before an emergency caesarean sectionIPG515
Implantation of a left ventricular assist device for destination therapy in people ineligible for heart transplantationIPG516
Insertion of endobronchial nitinol coils to improve lung function in emphysemaIPG517
Implantation of a duodenal–jejunal bypass liner for managing type 2 diabetesIPG518
Rivaroxaban for preventing adverse outcomes after acute management of acute coronary syndromeTA335
Empagliflozin in combination therapy for treating type 2 diabetesTA336
Rifaximin for preventing episodes of overt hepatic encephalopathyTA337
Obesity preventionCG43
Excess winter deaths and illness and the health risks associated with cold homesNG6
Medicines optimisation: the safe and effective use of medicines to enable the best possible outcomesNG5
VibraTip for testing vibration perception to detect diabetic peripheral neuropathyMTG22
Safe midwifery staffing for maternity settingsNG4
Bladder cancer: diagnosis and managementNG2
Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapyTA329
Sofosbuvir for treating chronic hepatitis CTA330
Axitinib for treating advanced renal cell carcinoma after failure of prior systemic treatmentTA333
Regorafenib for metastatic colorectal cancer after treatment for metastatic disease (terminated appraisal)TA334
Flexible endoscopic treatment of a pharyngeal pouchIPG513
Eculizumab for treating atypical haemolytic uraemic syndromeHST1
Implantation of a shock or load absorber for mild to moderate symptomatic medial knee osteoarthritisIPG512
Open reduction of slipped capital femoral epiphysisIPG511
Hysteroscopic metroplasty of a uterine septum for primary infertilityIPG509
Hysteroscopic metroplasty of a uterine septum for recurrent miscarriageIPG510
Vemurafenib for treating locally advanced or metastatic BRAF V600 mutation‑positive malignant melanomaTA269
Single‑incision laparoscopic cholecystectomyIPG508
Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolismTA327
Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustmentDG16
Telemetric adjustable pulmonary artery banding for pulmonary hypertension in infants with congenital heart defectsIPG505
Insertion of an annular disc implant at lumbar discectomyIPG506
Insertion of a collagen plug to close an abdominal wall enterocutaneous fistulaIPG507
Erythropoiesis‑stimulating agents (epoetin and darbepoetin) for treating anaemia in people with cancer having chemotherapyTA323
Dual‑chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome without atrioventricular blockTA324
Nalmefene for reducing alcohol consumption in people with alcohol dependenceTA325
Imatinib for the adjuvant treatment of gastrointestinal stromal tumoursTA326
The ReCell Spray‑On Skin system for treating skin loss, scarring and depigmentation after burn injuryMTG21
Dual‑chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome and/or atrioventricular blockTA88
Gallstone disease: diagnosis and managementCG188
Oral health: local authorities and partnersPH55
Dabrafenib for treating unresectable or metastatic BRAF V600 mutation‑positive melanomaTA321
Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependenceCG115
Combined endoscopic and laparoscopic removal of colonic polypsIPG503
Drug allergy: diagnosis and managementCG183
Total prosthetic replacement of the temporomandibular jointIPG500
Dimethyl fumarate for treating relapsing‑remitting multiple sclerosisTA320
Minimally invasive video-assisted thyroidectomyIPG499
Minimally invasive video‑assisted parathyroidectomyIPG501
Assessing motility of the gastrointestinal tract using a wireless capsuleIPG502
Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems)DG13
Endoscopic radiofrequency ablation for Barrett's oesophagus with low‑grade dysplasia or no dysplasiaIPG496
Endoscopic radiofrequency ablation for squamous dysplasia of the oesophagusIPG497
Powered microdebrider turbinoplasty for inferior turbinate hypertrophyIPG498
Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimenTA316
Prasugrel with percutaneous coronary intervention for treating acute coronary syndromesTA317
Ipilimumab for previously untreated advanced (unresectable or metastatic) melanomaTA319
Safe staffing for nursing in adult inpatient wards in acute hospitalsSG1
Endoscopic saphenous vein harvest for coronary artery bypass graftingIPG494
Radiofrequency tissue reduction for turbinate hypertrophyIPG495
The geko device for reducing the risk of venous thromboembolismMTG19
Implantable cardioverter defibrillators and cardiac resynchronisation therapy for arrhythmias and heart failureTA314
Canagliflozin in combination therapy for treating type 2 diabetesTA315
Teriflunomide for treating relapsing–remitting multiple sclerosisTA303
Gastroelectrical stimulation for gastroparesisIPG489
Endoscopic thoracic sympathectomy for primary hyperhidrosis of the upper limbIPG487
Arthroscopic radiofrequency chondroplasty for discrete chondral defects of the kneeIPG493
Pressure ulcers: prevention and managementCG179
Afatinib for treating epidermal growth factor receptor mutation-positive locally advanced or metastatic non-small-cell lung cancerTA310
Bortezomib for induction therapy in multiple myeloma before high-dose chemotherapy and autologous stem cell transplantationTA311
Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreathDG12
Extracorporeal membrane oxygenation (ECMO) for acute heart failure in adultsIPG482
Insertion of a magnetic bead band for faecal incontinenceIPG483
Transoral carbon dioxide laser surgery for primary treatment of oropharyngeal malignancyIPG484
Faecal microbiota transplant for recurrent Clostridium difficile infectionIPG485
Rituximab in combination with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitisTA308
Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapyTA307
Managing medicines in care homesSC1
Psychosis and schizophrenia in adults: prevention and managementCG178
Electrochemotherapy for primary basal cell carcinoma and primary squamous cell carcinomaIPG478
Domestic violence and abuse: multi-agency workingPH50
Total hip replacement and resurfacing arthroplasty for end-stage arthritis of the hipTA304
Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusionTA305
Pixantrone monotherapy for treating multiply relapsed or refractory aggressive non-Hodgkin's B‑cell lymphomaTA306
Optical coherence tomography to guide percutaneous coronary interventionIPG481
Endoscopic thoracic sympathectomy for primary facial blushingIPG480
Insertion of prostatic urethral lift implants to treat lower urinary tract symptoms secondary to benign prostatic hyperplasiaIPG475
Transcranial magnetic stimulation for treating and preventing migraineIPG477
Arthroscopic trochleoplasty for patellar instabilityIPG474
Radiofrequency ablation of the soft palate for snoringIPG476
Percutaneous closure of patent foramen ovale to prevent recurrent cerebral embolic eventsIPG472
Uterine artery embolisation for treating adenomyosisIPG473
Negative pressure wound therapy for the open abdomenIPG467
Phrenic nerve transfer in brachial plexus injuryIPG468
Implantation of a duodenal–jejunal bypass sleeve for managing obesityIPG471
Peginterferon alfa and ribavirin for treating chronic hepatitis C in children and young peopleTA300
Canakinumab for treating systemic juvenile idiopathic arthritis (terminated appraisal)TA302
Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis CTA106
Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis CTA75
Faecal calprotectin diagnostic tests for inflammatory diseases of the bowelDG11
Photochemical corneal collagen cross‑linkage using riboflavin and ultraviolet A for keratoconus and keratectasiaIPG466
Endoscopic radiofrequency ablation for gastro-oesophageal reflux diseaseIPG461
Translaryngeal tracheostomyIPG462
EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancerDG9
Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancerDG8
Pazopanib for the first-line treatment of advanced renal cell carcinomaTA215
Varicose veins: diagnosis and managementCG168
Aripiprazole for treating moderate to severe manic episodes in adolescents with bipolar I disorderTA292
Aflibercept solution for injection for treating wet age‑related macular degenerationTA294
Insertion of customised exposed titanium implants, without soft tissue cover, for complex orofacial reconstructionIPG457
Selective internal radiation therapy for primary hepatocellular carcinomaIPG460
Insertion of customised titanium implants, with soft tissue cover, for orofacial reconstructionIPG449
Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolismTA287
Mirabegron for treating symptoms of overactive bladderTA290
Falls in older people: assessing risk and preventionCG161
Social anxiety disorder: recognition, assessment and treatmentCG159
Bevacizumab in combination with paclitaxel and carboplatin for first-line treatment of advanced ovarian cancerTA284
Bevacizumab in combination with gemcitabine and carboplatin for treating the first recurrence of platinum-sensitive advanced ovarian cancerTA285
Loxapine inhalation for treating acute agitation and disturbed behaviours associated with schizophrenia and bipolar disorder (terminated appraisal)TA286
Occipital nerve stimulation for intractable chronic migraineIPG452
Corneal inlay implantation for correction of presbyopiaIPG455
Omalizumab for treating severe persistent allergic asthmaTA278
Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for treating osteoporotic vertebral compression fracturesTA279
Antisocial personality disorder: prevention and managementCG77
Electrochemotherapy for metastases in the skin from tumours of non-skin origin and melanomaIPG446
Insertion of endobronchial valves for persistent air leaksIPG448
Percutaneous electrical nerve stimulation for refractory neuropathic painIPG450
Peripheral nerve-field stimulation for chronic low back painIPG451
Colistimethate sodium and tobramycin dry powders for inhalation for treating pseudomonas lung infection in cystic fibrosisTA276
Methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care (terminated appraisal)TA277
Irreversible electroporation for treating primary lung cancer and metastases in the lungIPG441
Irreversible electroporation for treating renal cancerIPG443
Irreversible electroporation for treating liver metastasesIPG445
Ultrasound-guided foam sclerotherapy for varicose veinsIPG440
Percutaneous pulmonary valve implantation for right ventricular outflow tract dysfunctionIPG436
Autologous blood injection for plantar fasciitisIPG437
Autologous blood injection for tendinopathyIPG438
Deep dermal injection of non-absorbable gel polymer for HIV-related lipoatrophyIPG439
Vinflunine for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tractTA272
Tadalafil for the treatment of symptoms associated with benign prostatic hyperplasia (terminated appraisal)TA273
Ipilimumab for previously treated advanced (unresectable or metastatic) melanomaTA268
Decitabine for the treatment of acute myeloid leukaemia (terminated appraisal)TA270
Dronedarone for the treatment of non-permanent atrial fibrillationTA197
Mannitol dry powder for inhalation for treating cystic fibrosisTA266
Ivabradine for treating chronic heart failureTA267
Laparoscopic gastric plication for the treatment of severe obesityIPG432
Percutaneous laser atherectomy as an adjunct to balloon angioplasty (with or without stenting) for peripheral arterial diseaseIPG433
Radiofrequency cold ablation for respiratory papillomatosisIPG434
Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact MDG6
Denosumab for the prevention of skeletal-related events in adults with bone metastases from solid tumoursTA265
Alteplase for treating acute ischaemic strokeTA264
Neutropenic sepsis: prevention and management in people with cancerCG151
SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liverDG5
Mega Soft Patient Return Electrode for use during monopolar electrosurgeryMTG11
Bevacizumab in combination with capecitabine for the first-line treatment of metastatic breast cancerTA263
Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolismTA261
Endovascular stent insertion for intracranial atherosclerotic diseaseIPG429
Partial replacement of the meniscus of the knee using a biodegradable scaffoldIPG430
Sickle cell disease: managing acute painful episodes in hospitalCG143
Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone-receptor-positive breast cancer that overexpresses HER2TA257
Erlotinib for the first-line treatment of locally advanced or metastatic EGFR-TK mutation-positive non-small-cell lung cancerTA258
Botulinum toxin type A for the prevention of headaches in adults with chronic migraineTA260
Percutaneous balloon cryoablation for pulmonary vein isolation in atrial fibrillationIPG427
Focal therapy using cryoablation for localised prostate cancerIPG423
Micropressure therapy for refractory Ménière's diseaseIPG426
Fingolimod for the treatment of highly active relapsing–remitting multiple sclerosisTA254
Incisionless otoplastyIPG422
Pharmalgen for the treatment of bee and wasp venom allergyTA246
Tocilizumab for the treatment of rheumatoid arthritisTA247
Cetuximab, bevacizumab and panitumumab for the treatment of metastatic colorectal cancer after first-line chemotherapy: Cetuximab (monotherapy or combination chemotherapy), bevacizumab (in combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-line chemotherapyTA242
Rituximab for the first-line treatment of stage III-IV follicular lymphomaTA243
Apixaban for the prevention of venous thromboembolism after total hip or knee replacement in adultsTA245
Breast reconstruction using lipomodelling after breast cancer treatmentIPG417
Bevacizumab and cetuximab for the treatment of metastatic colorectal cancerTA118
Epiretinal brachytherapy for wet age-related macular degenerationIPG415
Service user experience in adult mental health: improving the experience of care for people using adult NHS mental health servicesCG136
Tocilizumab for the treatment of systemic juvenile idiopathic arthritisTA238
Fulvestrant for the treatment of locally advanced or metastatic breast cancerTA239
Drainage, irrigation and fibrinolytic therapy (DRIFT) for post-haemorrhagic hydrocephalus in preterm infantsIPG412
Magnetic resonance image-guided transcutaneous focused ultrasound for uterine fibroidsIPG413
Single-port laparoscopic nephrectomyIPG414
Healthcare-associated infections: prevention and controlPH36
The EOS 2D/3D imaging systemDG1
Ticagrelor for the treatment of acute coronary syndromesTA236
Mifamurtide for the treatment of osteosarcomaTA235
Arthroscopic femoro–acetabular surgery for hip impingement syndromeIPG408
Minimally invasive oesophagectomyIPG407
Laparoscopic cryotherapy for renal cancerIPG405
Percutaneous cryotherapy for renal cancerIPG402
Open femoro–acetabular surgery for hip impingement syndromeIPG403
Bortezomib and thalidomide for the first‑line treatment of multiple myelomaTA228
Dexamethasone intravitreal implant for the treatment of macular oedema secondary to retinal vein occlusionTA229
Agomelatine for the treatment of major depressive episodes (terminated appraisal)TA231
Ambulight PDT for the treatment of non-melanoma skin cancerMTG6
The MIST Therapy system for the promotion of wound healingMTG5
Myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarctionTA73
Erlotinib monotherapy for maintenance treatment of non-small-cell lung cancerTA227
Endoscopic radical inguinal lymphadenectomyIPG398
Thoracoscopic exclusion of the left atrial appendage (with or without surgical ablation) for non-valvular atrial fibrillation for the prevention of thromboembolismIPG400
Golimumab for the treatment of rheumatoid arthritis after the failure of previous disease-modifying anti-rheumatic drugsTA225
Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphomaTA226
Endoscopic radiofrequency therapy of the anal sphincter for faecal incontinenceIPG393
Percutaneous tibial nerve stimulation for faecal incontinenceIPG395
Trabeculotomy ab interno for open angle glaucomaIPG397
Cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial diseaseTA223
Carotid artery stent placement for symptomatic extracranial carotid stenosisIPG389
Endovascular stent-grafting of popliteal aneurysmsIPG390
Extracorporeal membrane oxygenation for severe acute respiratory failure in adultsIPG391
Stent insertion for bleeding oesophageal varicesIPG392
Golimumab for the treatment of psoriatic arthritisTA220
Coexisting severe mental illness (psychosis) and substance misuse: assessment and management in healthcare settingsCG120
Hand allotransplantationIPG383
Percutaneous retroperitoneal endoscopic necrosectomyIPG384
Laser correction of refractive error following non-refractive ophthalmic surgeryIPG385
Deep brain stimulation for intractable trigeminal autonomic cephalalgiasIPG381
Deep brain stimulation for refractory chronic pain syndromes (excluding headache)IPG382
Azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myeloid leukaemiaTA218
Food allergy in under 19s: assessment and diagnosisCG116
Percutaneous atherectomy of femoropopliteal arterial lesions with plaque excision devicesIPG380
Bevacizumab in combination with a taxane for the first-line treatment of metastatic breast cancerTA214
Bendamustine for the first-line treatment of chronic lymphocytic leukaemiaTA216
Extracorporeal shockwave therapy for refractory greater trochanteric pain syndromeIPG376
Off-pump coronary artery bypass graftingIPG377
Percutaneous laser coronary angioplastyIPG378
Aripiprazole for the treatment of schizophrenia in people aged 15 to 17 yearsTA213
Thoracoscopic repair of congenital diaphragmatic hernia in neonatesIPG379
Distal iliotibial band lengthening for refractory greater trochanteric pain syndromeIPG375
Sedation in under 19s: using sedation for diagnostic and therapeutic proceduresCG112
Cryotherapy for the treatment of liver metastasesIPG369
Percutaneous closure of patent foramen ovale for recurrent migraineIPG370
Percutaneous closure of patent foramen ovale for the secondary prevention of recurrent paradoxical embolism in diversIPG371
Percutaneous radiofrequency ablation for primary or secondary lung cancersIPG372
Selective dorsal rhizotomy for spasticity in cerebral palsyIPG373
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular eventsTA210
Prucalopride for the treatment of chronic constipation in womenTA211
Bevacizumab in combination with oxaliplatin and either fluorouracil plus folinic acid or capecitabine for the treatment of metastatic colorectal cancerTA212
Interspinous distraction procedures for lumbar spinal stenosis causing neurogenic claudicationIPG365
Non-rigid stabilisation techniques for the treatment of low back painIPG366
Uterine artery embolisation for fibroidsIPG367
Unintentional injuries in the home: interventions for under 15sPH30
Trastuzumab for the treatment of HER2-positive metastatic gastric cancerTA208
Imatinib for the treatment of unresectable and/or metastatic gastrointestinal stromal tumoursTA209
Imatinib for the treatment of unresectable and/or metastatic gastro-intestinal stromal tumoursTA86
Bedwetting in under 19sCG111
Endoscopic mucosal resection and endoscopic submucosal dissection of non-ampullary duodenal lesionsIPG359
Endoscopic submucosal dissection of gastric lesionsIPG360
Insertion of metal rib reinforcements to stabilise a flail chest wallIPG361
Percutaneous posterior tibial nerve stimulation for overactive bladder syndromeIPG362
Minimally invasive total hip replacementIPG363
Transperineal template biopsy and mapping of the prostateIPG364
Denosumab for the prevention of osteoporotic fractures in postmenopausal womenTA204
Bendamustine for the treatment of indolent (low grade) non-Hodgkin's lymphoma that is refractory to rituximab (terminated appraisal)TA206
Temsirolimus for the treatment of relapsed or refractory mantle cell lymphoma (terminated appraisal)TA207
Pregnancy and complex social factors: a model for service provision for pregnant women with complex social factorsCG110
Endoscopic submucosal dissection of oesophageal dysplasia and neoplasiaIPG355
Laparoscopic hysterectomy (including laparoscopic total hysterectomy and laparoscopically assisted vaginal hysterectomy) for endometrial cancerIPG356
Percutaneous intradiscal laser ablation in the lumbar spineIPG357
Phototherapeutic laser keratectomy for corneal surface irregularitiesIPG358
Peginterferon alfa and ribavirin for the treatment of chronic hepatitis CTA200
Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitorTA195
Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritisTA199
Percutaneous mitral valve annuloplastyIPG352
Percutaneous radiofrequency ablation for renal cancerIPG353
Shoulder resurfacing arthroplastyIPG354
Rituximab for the treatment of relapsed or refractory chronic lymphocytic leukaemiaTA193
Capecitabine for the treatment of advanced gastric cancerTA191
Gefitinib for the first-line treatment of locally advanced or metastatic non-small-cell lung cancerTA192
Stapled transanal rectal resection for obstructed defaecation syndromeIPG351
Percutaneous occlusion of the left atrial appendage in non-valvular atrial fibrillation for the prevention of thromboembolismIPG349
Photodynamic therapy for Barrett's oesophagusIPG350
Alcohol-use disorders: preventionPH24
Epithelial radiofrequency ablation for Barrett's oesophagusIPG344
Mini-incision surgery for total knee replacementIPG345
Therapeutic hypothermia with intracorporeal temperature monitoring for hypoxic perinatal brain injuryIPG347
Human growth hormone (somatropin) for the treatment of growth failure in childrenTA188
Improving outcomes for people with skin tumours including melanomaCSG8
Limited macular translocation for wet age-related macular degenerationIPG339
Macular translocation with 360° retinotomy for wet age-related macular degenerationIPG340
Prosthetic intervertebral disc replacement in the cervical spineIPG341
Haemorrhoidal artery ligationIPG342
Infliximab and adalimumab for the treatment of Crohn's diseaseTA187
Arteriovenous crossing sheathotomy for branch retinal vein occlusionIPG334
Endoscopic submucosal dissection of lower gastrointestinal lesionsIPG335
Transcatheter endovascular closure of perimembranous ventricular septal defectIPG336
Endobronchial ultrasound-guided transbronchial biopsy for peripheral lung lesionsIPG337
Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromesTA47
Donor milk banks: service operationCG93
Surgical correction of hallux valgus using minimal access techniquesIPG332
Therapeutic endoscopic division of epidural adhesionsIPG333
Radiofrequency ablation for colorectal liver metastasesIPG327
Suction diathermy adenoidectomyIPG328
Balloon catheter insertion for Bartholin's cyst or abscessIPG323
Electrocautery cutting balloon treatment for pelviureteric junction obstructionIPG324
Endopyelotomy for pelviureteric junction obstructionIPG325
Laparoscopic augmentation cystoplasty (including clam cystoplasty)IPG326
Topotecan for the treatment of relapsed small-cell lung cancerTA184
Depression in adults with a chronic physical health problem: recognition and managementCG91
Topotecan for the treatment of recurrent and stage IVB cervical cancerTA183
Guidance on the use of electroconvulsive therapyTA59
Extracorporeal albumin dialysis for acute liver failureIPG316
Individually magnetic resonance imaging-designed unicompartmental interpositional implant insertion for osteoarthritis of the kneeIPG317
Sunitinib for the treatment of gastrointestinal stromal tumoursTA179
Pemetrexed for the first-line treatment of non-small-cell lung cancerTA181
Placement of pectus bar for pectus excavatum (also known as MIRPE or the Nuss procedure)IPG310
Extracorporeal shockwave therapy for refractory plantar fasciitisIPG311
Extracorporeal shockwave therapy for refractory tennis elbowIPG313
Alitretinoin for the treatment of severe chronic hand eczemaTA177
Bevacizumab (first-line), sorafenib (first- and second-line), sunitinib (second-line) and temsirolimus (first-line) for the treatment of advanced and/or metastatic renal cell carcinomaTA178
Prosthetic intervertebral disc replacement in the lumbar spineIPG306
Image-guided radiofrequency excision biopsy of breast lesionsIPG308
Sinus tarsi implant insertion for mobile flatfootIPG305
Tenofovir disoproxil for the treatment of chronic hepatitis BTA173
Rituximab for the first-line treatment of chronic lymphocytic leukaemiaTA174
Percutaneous endoscopic laser cervical discectomyIPG303
Corneal endothelial transplantationIPG304
Tenotomy of horizontal eye muscles for nystagmus (with reattachment at their original insertions)IPG299
Transmyocardial laser revascularisation for refractory angina pectorisIPG301
Percutaneous laser revascularisation for refractory angina pectorisIPG302
Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and managementCG84
Combined bony and soft tissue reconstruction for hip joint stabilisation in proximal focal femoral deficiency (PFFD)IPG297
Ex-vivo hepatic resection and reimplantation for liver cancerIPG298
Endoscopic mastectomy and endoscopic wide local excision for breast cancerIPG296
Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adultsTA170
Percutaneous (non-thoracoscopic) epicardial catheter radiofrequency ablation for atrial fibrillationIPG294
Percutaneous (non-thoracoscopic) epicardial catheter radiofrequency ablation for ventricular tachycardiaIPG295
Rehabilitation after critical illness in adultsCG83
Photodynamic therapy for brain tumoursIPG290
Implantation of an opaque intraocular lens for intractable double visionIPG293
Sunitinib for the first-line treatment of advanced and/or metastatic renal cell carcinomaTA169
Extracorporeal photopheresis for Crohn's diseaseIPG288
Intraocular lens insertion for correction of refractive error, with preservation of the natural lensIPG289
Laparoscopic cystectomyIPG287
Amantadine, oseltamivir and zanamivir for the treatment of influenzaTA168
Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherenceCG76
Borderline personality disorder: recognition and managementCG78
Functional electrical stimulation for drop foot of central neurological originIPG278
Ultrasound-guided regional nerve blockIPG285
Thoracoscopic epicardial radiofrequency ablation for atrial fibrillationIPG286
Machine perfusion systems and cold static storage of kidneys from deceased donorsTA165
Infliximab for acute exacerbations of ulcerative colitisTA163
Laparoscopic prostatectomy for benign prostatic obstructionIPG275
Transabdominal artificial bowel sphincter implantation for faecal incontinenceIPG276
Mental wellbeing in over 65s: occupational therapy and physical activity interventionsPH16
Spinal cord stimulation for chronic pain of neuropathic or ischaemic originTA159
Balloon catheter dilation of paranasal sinus ostia for chronic sinusitisIPG273
Autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomyIPG274
Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adultsTA157
Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenzaTA158
Total wrist replacementIPG271
Routine antenatal anti-D prophylaxis for women who are rhesus D negativeTA156
Entecavir for the treatment of chronic hepatitis BTA153
Telbivudine for the treatment of chronic hepatitis BTA154
Brachytherapy as the sole method of adjuvant radiotherapy for breast cancer after local excisionIPG268
Laparoscopic gastrectomy for cancerIPG269
Direct skeletal fixation of limb or digit prostheses using intraosseous transcutaneous implantsIPG270
Continuous subcutaneous insulin infusion for the treatment of diabetes mellitusTA151
Lumbar infusion test for the investigation of normal pressure hydrocephalusIPG263
Implantation of multifocal (non-accommodative) intraocular lenses during cataract surgeryIPG264
Bevacizumab for the treatment of non-small-cell lung cancer (terminated appraisal)TA148
Carmustine implants for the treatment of recurrent glioblastoma multiforme (terminated appraisal)TA149
Cetuximab for the treatment of locally advanced squamous cell cancer of the head and neckTA145
Adalimumab for the treatment of adults with psoriasisTA146
Endoaortic balloon occlusion for cardiac surgeryIPG261
Intraoperative red blood cell salvage during radical prostatectomy or radical cystectomyIPG258
Interstitial photodynamic therapy for malignant parotid tumoursIPG259
Allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitusIPG257
Intraoperative nerve monitoring during thyroid surgeryIPG255
Inhaled corticosteroids for the treatment of chronic asthma in adults and in children aged 12 years and overTA138
Laser-assisted cerebral vascular anastomosis without temporary arterial occlusionIPG252
Laparoscopic mobilisation of the greater omentum for breast reconstructionIPG253
Endobronchial ultrasound-guided transbronchial needle aspiration for mediastinal massesIPG254
Structural neuroimaging in first-episode psychosisTA136
Rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphomaTA137
Ultrasound-guided catheterisation of the epidural spaceIPG249
Infliximab for the treatment of adults with psoriasisTA134
Pemetrexed for the treatment of malignant pleural mesotheliomaTA135
Thoracoscopically assisted mitral valve surgeryIPG245
Hybrid procedure for interim management of hypoplastic left heart syndrome in neonatesIPG246
Thoracoscopic excision of mediastinal parathyroid tumoursIPG247
Thoracoscopic aortopexy for severe primary tracheomalaciaIPG243
Grenz rays therapy for inflammatory skin conditionsIPG236
Mini/micro screw implantation for orthodontic anchorageIPG238
Laparoscopic techniques for hysterectomyIPG239
Soft-palate implants for simple snoringIPG240
Soft-palate implants for obstructive sleep apnoeaIPG241
Inhaled corticosteroids for the treatment of chronic asthma in children under the age of 12 yearsTA131
Laparoscopic uterine nerve ablation (LUNA) for chronic pelvic painIPG234
Bortezomib monotherapy for relapsed multiple myelomaTA129
Serial transverse enteroplasty procedure (STEP) for bowel lengthening in parenteral nutrition-dependent childrenIPG232
Stapled haemorrhoidopexy for the treatment of haemorrhoidsTA128
Laparoscopic repair of abdominal aortic aneurysmIPG229
Arthroscopic knee washout, with or without debridement, for the treatment of osteoarthritisIPG230
Pemetrexed for the treatment of non-small-cell lung cancerTA124
Therapeutic percutaneous image-guided aspiration of spinal cystsIPG223
Acutely ill adults in hospital: recognising and responding to deteriorationCG50
Drug misuse in over 16s: opioid detoxificationCG52
Drug misuse in over 16s: psychosocial interventionsCG51
Laparoscopic deroofing of simple renal cystsIPG226
Corneal implants for keratoconusIPG227
Corneal implants for the correction of refractive errorIPG225
Varenicline for smoking cessationTA123
Faecal incontinence in adults: managementCG49
Endoscopic augmentation of the lower oesophageal sphincter using hydrogel implants for the treatment of gastro-oesophageal reflux diseaseIPG222
Carmustine implants and temozolomide for the treatment of newly diagnosed high-grade gliomaTA121
Therapeutic sialendoscopyIPG218
Lower limb deep vein valve reconstruction for chronic deep venous incompetenceIPG219
Tissue-cultured limbal stem cell allograft transplantation for regrowth of corneal epitheliumIPG216
Laparoscopic nephrolithotomy and pyelolithotomyIPG212
Microwave ablation of hepatocellular carcinomaIPG214
Radiofrequency-assisted liver resectionIPG211
Laparoscopic insertion of peritoneal dialysis catheterIPG208
Implantation of accommodating intraocular lenses for cataractIPG209
Injectable bulking agents for faecal incontinenceIPG210
Fludarabine monotherapy for the first-line treatment of chronic lymphocytic leukaemiaTA119
Laparoscopic distal pancreatectomyIPG204
Fetal cystoscopy for the diagnosis and treatment of lower urinary outflow tract obstructionIPG205
Palliative photodynamic therapy for advanced oesophageal cancerIPG206
Cinacalcet for the treatment of secondary hyperparathyroidism in patients with end-stage renal disease on maintenance dialysis therapyTA117
Methadone and buprenorphine for the management of opioid dependenceTA114
Naltrexone for the management of opioid dependenceTA115
Gemcitabine for the treatment of metastatic breast cancerTA116
Intrauterine laser ablation of placental vessels for the treatment of twin-to-twin transfusion syndromeIPG198
Septostomy with or without amnioreduction for the treatment of twin-to-twin transfusion syndromeIPG199
Photodynamic therapy for early-stage oesophageal cancerIPG200
Fetal vesico–amniotic shunt for lower urinary tract outflow obstructionIPG202
Therapeutic amnioinfusion for oligohydramnios during pregnancy (excluding labour)IPG192
Laparoscopic radical prostatectomyIPG193
Insertion of pleuro–amniotic shunt for fetal pleural effusionIPG190
Deep brain stimulation for tremor and dystonia (excluding Parkinson's disease)IPG188
Laparoscopic surgery for colorectal cancerTA105
High-intensity focused ultrasound for atrial fibrillation in association with other cardiac surgeryIPG184
Tonsillectomy using laserIPG186
Catheterless oesophageal pH monitoringIPG187
Etanercept and efalizumab for the treatment of adults with psoriasisTA103
Improving outcomes for people with brain and other central nervous system tumoursCSG10
Percutaneous cementoplasty for palliative treatment of bony malignanciesIPG179
Percutaneous laser therapy for fetal tumoursIPG180
Short-term circulatory support with left ventricular assist devices as a bridge to cardiac transplantation or recoveryIPG177
Tonsillectomy using ultrasonic scalpelIPG178
Docetaxel for the treatment of hormone-refractory metastatic prostate cancerTA101
Living-donor lung transplantation for end-stage lung diseaseIPG170
Laparoscopic helium plasma coagulation for the treatment of endometriosisIPG171
High dose rate brachytherapy in combination with external-beam radiotherapy for localised prostate cancerIPG174
Percutaneous fetal balloon valvuloplasty for pulmonary atresia with intact ventricular septumIPG176
Percutaneous radiofrequency ablation for atrial fibrillationIPG168
Balloon kyphoplasty for vertebral compression fracturesIPG166
Retrograde urethral sphincterometryIPG167
Capecitabine and oxaliplatin in the adjuvant treatment of stage III (Dukes' C) colon cancerTA100
Laparoscopic retroperitoneal lymph node dissection for testicular cancerIPG158
Stimulated graciloplasty for faecal incontinenceIPG159
High dose rate brachytherapy for carcinoma of the cervixIPG160
Percutaneous endoscopic colostomyIPG161
Stent-graft placement in abdominal aortic aneurysmIPG163
Photorefractive (laser) surgery for the correction of refractive errorsIPG164
Endometrial cryotherapy for menorrhagiaIPG157
Improving outcomes for people with sarcomaCSG9
Photodynamic therapy for non-melanoma skin tumours (including premalignant and primary non-metastatic skin lesions)IPG155
Image-guided vacuum-assisted excision biopsy of benign breast lesionsIPG156
Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis BTA96
Laparoscopic partial nephrectomyIPG151
Foker technique for long-gap oesophageal atresiaIPG153
Retrobulbar irradiation for thyroid eye diseaseIPG148
Division of ankyloglossia (tongue-tie) for breastfeedingIPG149
Electrosurgery (diathermy and coblation) for tonsillectomyIPG150
Direct C1 lateral mass screw for cervical spine stabilisationIPG146
Endoscopic axillary lymph node retrieval for breast cancerIPG147
Obsessive-compulsive disorder and body dysmorphic disorder: treatmentCG31
Metatarsophalangeal joint replacement of the halluxIPG140
Automated percutaneous mechanical lumbar discectomyIPG141
Cryotherapy for malignant endobronchial obstructionIPG142
Intraoperative blood cell salvage in obstetricsIPG144
Photodynamic therapy for localised inoperable endobronchial cancerIPG137
Cryotherapy as a primary treatment for prostate cancerIPG145
Intramural urethral bulking procedures for stress urinary incontinence in womenIPG138
Improving outcomes in children and young people with cancerCSG7
Laparoscopic nephrectomy (including nephroureterectomy)IPG136
Low dose rate brachytherapy for localised prostate cancerIPG132
Photodynamic therapy for bile duct cancerIPG134
Laparoscopic liver resectionIPG135
HealOzone for the treatment of tooth decay (occlusal pit and fissure caries and root caries)TA92
Leukapheresis for inflammatory bowel diseaseIPG126
Collagen injection for vocal cord augmentationIPG130
Endovascular stent–graft placement in thoracic aortic aneurysms and dissectionsIPG127
Interstitial laser therapy for fibroadenomas of the breastIPG131
Totally endoscopic robotically assisted coronary artery bypass graftingIPG128
Computed tomographic colonography (virtual colonoscopy)IPG129
Radiofrequency ablation for atrial fibrillation in association with other cardiac surgeryIPG121
Microwave ablation for atrial fibrillation in association with other cardiac surgeryIPG122
Cryoablation for atrial fibrillation in association with other cardiac surgeryIPG123
Cryotherapy for recurrent prostate cancerIPG119
Guidance on the use of paclitaxel in the treatment of ovarian cancerTA55
High-intensity focused ultrasound for prostate cancerIPG118
Artificial metacarpophalangeal and interphalangeal joint replacement for end-stage arthritisIPG110
Artificial trapeziometacarpal joint replacement for end-stage osteoarthritisIPG111
Endoscopic dacryocystorhinostomyIPG113
Lung volume reduction surgery for advanced emphysemaIPG114
Coil embolisation of ruptured intracranial aneurysmsIPG106
Auditory brain stem implantsIPG108
Coil embolisation of unruptured intracranial aneurysmsIPG105
Wireless capsule endoscopy for investigation of the small bowelIPG101
Improving outcomes in head and neck cancersCSG6
Sacral nerve stimulation for faecal incontinenceIPG99
Dental checks: intervals between oral health reviewsCG19
Radiofrequency valvotomy for pulmonary atresiaIPG95
Endovascular closure of atrial septal defectIPG96
Endovascular closure of patent ductus arteriosusIPG97
Intraoperative fluorescence angiography for the evaluation of coronary artery bypass graft patencyIPG98
Interstitial laser therapy for breast cancerIPG89
Intralesional photocoagulation of subcutaneous congenital vascular disordersIPG90
Laparoscopic surgery for inguinal hernia repairTA83
Selective peripheral denervation for cervical dystoniaIPG80
Supraorbital minicraniotomy for intracranial aneurysmIPG84
Endovascular atrial septostomyIPG86
Photodynamic therapy for advanced bronchial carcinomaIPG87
Tacrolimus and pimecrolimus for atopic eczemaTA82
Frequency of application of topical corticosteroids for atopic eczemaTA81
Balloon dilatation of systemic to pulmonary arterial shunts in childrenIPG77
Balloon valvuloplasty for aortic valve stenosis in adults and childrenIPG78
Balloon dilatation with or without stenting for pulmonary artery or non-valvar right ventricular outflow tract obstruction in childrenIPG76
Scleral expansion surgery for presbyopiaIPG70
Balloon angioplasty of pulmonary vein stenosis in infantsIPG75
Stent placement for vena caval obstructionIPG79
Balloon angioplasty with or without stenting for coarctation or recoarctation of the aorta in adults and childrenIPG74
Fallopian tube recanalisation by guidewireIPG71
Insertion of hydrogel keratoprosthesisIPG69
Lumbar subcutaneous shuntIPG68
Balloon dilatation of pulmonary valve stenosisIPG67
Artificial anal sphincter implantationIPG66
Subthalamotomy for Parkinson's diseaseIPG65
Sacral nerve stimulation for urge incontinence and urgency-frequencyIPG64
Falloposcopy with coaxial catheterIPG62
Laser sheath removal of pacing leadsIPG63
Thrombin injections for pseudoaneurysmsIPG60
Laparoscopic live donor simple nephrectomyIPG57
Transpupillary thermotherapy for age-related macular degenerationIPG58
Subfascial endoscopic perforator vein surgeryIPG59
Percutaneous endoscopic laser thoracic discectomyIPG61
Complete cytoreduction for pseudomyxoma peritonei (Sugarbaker technique)IPG56
Endoscopic injection of bulking agents for gastro-oesophageal reflux diseaseIPG55
Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomniaTA77
Fluid-filled thermal balloon and microwave endometrial ablation techniques for heavy menstrual bleedingTA78
Improving supportive and palliative care for adults with cancerCSG4
Photodynamic endometrial ablationIPG47
Vagus nerve stimulation for refractory epilepsy in childrenIPG50
Radiotherapy for age-related macular degenerationIPG49
Laparoscopic pyeloplastyIPG46
Computed tomography-guided thermocoagulation of osteoid osteomaIPG53
Endovenous laser treatment of the long saphenous veinIPG52
Cyanoacrylate instillation for occlusion of parotid sinusesIPG42
Partial left ventriculectomy (the Batista procedure)IPG41
Non-surgical reduction of the myocardial septumIPG40
Needle fasciotomy for Dupuytren's contractureIPG43
Transilluminated powered phlebectomy for varicose veinsIPG37
Extracorporeal membrane oxygenation (ECMO) in postneonatal childrenIPG38
Pre-hospital initiation of fluid replacement therapy in traumaTA74
Circular stapled haemorrhoidectomyIPG34
Endoscopic laser foraminoplastyIPG31
Laparo-endogastric surgeryIPG25
Extracorporeal shockwave therapy for Peyronie's diseaseIPG29
Endoscopic transsphenoidal pituitary adenoma resectionIPG32
Magnetic resonance (MR) image-guided percutaneous laser ablation of uterine fibroidsIPG30
Holmium laser prostatectomyIPG17
Bone-anchored cystourethropexyIPG18
Deep brain stimulation for Parkinson's diseaseIPG19
Endoscopic stapling of pharyngeal pouchIPG22
Laparoscopic laser myomectomyIPG23
Transurethral electrovaporisation of the prostateIPG14
Guidance on the use of liquid-based cytology for cervical screeningTA69
Percutaneous vertebroplastyIPG12
Radiofrequency ablation of varicose veinsIPG8
Human growth hormone (somatropin) in adults with growth hormone deficiencyTA64
Radiofrequency ablation of hepatocellular carcinomaIPG2
Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancerTA61
Guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarctionTA52
Guidance on the use of ultrasound locating devices for placing central venous cathetersTA49
Improving outcomes in urological cancersCSG2
Improving outcomes in breast cancerCSG1
Inhaler devices for routine treatment of chronic asthma in older children (aged 5–15 years)TA38
Guidance on the use of trastuzumab for the treatment of advanced breast cancerTA34
Guidance on the use of fludarabine for B-cell chronic lymphocytic leukaemiaTA29
Guidance on the use of riluzole (Rilutek) for the treatment of motor neurone diseaseTA20
Guidance on the use of inhaler systems (devices) in children under the age of 5 years with chronic asthmaTA10
Guidance on the extraction of wisdom teethTA1

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