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Guidance, NICE advice and quality standards in development
Title
Type
Expected publication date
12 SQ-HDM SLIT for treating allergic rhinitis and allergic asthma caused by house dust mites (review of TA834) [ID6280]
Technology appraisal guidance
12 February 2025
Direct skeletal fixation of limb or digit prostheses using intraosseous transcutaneous implants
Interventional procedures guidance
13 November 2024
Fedratinib for treating disease-related splenomegaly or symptoms in myelofibrosis (Review of TA756) [ID5115]
Technology appraisal guidance
16 October 2024
Osimertinib for adjuvant treatment of EGFR mutation-positive non-small-cell lung cancer after complete tumour resection (Review of TA761) [ID5120]
Technology appraisal guidance
14 August 2024
Digitally enabled therapy for chronic tic disorders and Tourette Syndrome
Medical technologies guidance
19 December 2024
Hydromethylthionine mesylate for treating mild cognitive impairment or mild or moderate dementia caused by Alzheimer's disease ID6343
Technology appraisal guidance
TBC
Linzagolix for treating pain caused by endometriosis [ID6357]
Technology appraisal guidance
TBC
Givinostat for treating Duchenne muscular dystrophy in people 6 years and over [ID6323]
Technology appraisal guidance
TBC
Elafibranor for treating primary biliary cholangitis [ID6331]
Technology appraisal guidance
TBC
Avapritinib for treating advanced systemic mastocytosis ID3770
Technology appraisal guidance
TBC
Epcoritamab for treating relapsed or refractory follicular lymphoma after 2 or more treatments [ID6338]
Technology appraisal guidance
TBC
Venetoclax with bortezomib and dexamethasone for treating relapsed or refractory multiple myeloma ID1565
Technology appraisal guidance
TBC
Nusinersen and risdiplam for treating spinal muscular atrophy (review of TA588 and TA755) [ID6195]
Technology appraisal guidance
4 December 2024
Tafamidis for treating transthyretin amyloidosis with cardiomyopathy [ID6327]
Technology appraisal guidance
19 June 2024
Teclistamab for treating relapsed or refractory multiple myeloma after 3 treatments (Review of TA869) [ID6333]
Technology appraisal guidance
14 August 2024
Cerliponase alfa for treating neuronal ceroid lipofuscinosis type 2 (review of HST12) [ID6145]
Technology appraisal guidance
23 October 2024
Artificial intelligence (AI) technologies for assessing skin lesions referred on the urgent suspected cancer pathway
Health technology evaluation
TBC
Marstacimab for treating severe haemophilia A or severe haemophilia B in people 12 years and over [ID6342]
Technology appraisal guidance
TBC
Pitolisant for treating narcolepsy in children and young people 6 to 17 years ID6353
Technology appraisal guidance
TBC
Eplontersen for treating polyneuropathy caused by hereditary transthyretin amyloidosis [ID6337]
Technology appraisal guidance
14 August 2024
Vepdegestrant for treating hormone receptor-positive HER2-negative metastatic breast cancer after endocrine treatment [ID6360]
Technology appraisal guidance
TBC
Datopotamab deruxtecan for previously treated hormone receptor-positive HER2-negative unresectable or metastatic breast cancer [ID6348]
Technology appraisal guidance
TBC
Pembrolizumab–vibostolimab with etoposide and platinum-based chemotherapy for untreated extensive-stage small-cell lung cancer [ID6361]
Technology appraisal guidance
TBC
Osimertinib with pemetrexed and platinum-based chemotherapy for untreated EGFR mutation-positive advanced non-small-cell lung cancer [ID6328]
Technology appraisal guidance
TBC
Molnupiravir for treating COVID 19 [ID6340]
Technology appraisal guidance
29 January 2025
Maralixibat for treating progressive familial intrahepatic cholestasis [ID3818]
Technology appraisal guidance
TBC
Odevixibat for treating cholestasis and pruritus in Alagille Syndrome [ID6181]
Technology appraisal guidance
TBC
Pegzilarginase for treating arginase-1 deficiency [ID4029]
Highly specialised technology
30 October 2024
Idebenone for treating visual impairment in Leber's hereditary optic neuropathy in people 12 years and over [ID547]
Technology appraisal guidance
TBC
Maralixibat for treating cholestatic pruritus in Alagille syndrome [ID3941]
Technology appraisal guidance
18 September 2024
Brentuximab vedotin with doxorubicin, dacarbazine and vinblastine for previously untreated late-stage classical Hodgkin lymphoma (including Review of TA594) [ID6334]
Technology appraisal guidance
13 November 2024
Nivolumab for adjuvant treatment of localised renal cell carcinoma [ID6362]
Technology appraisal guidance
TBC
Pembrolizumab with chemotherapy for treating platinum-resistant recurrent ovarian cancer after 1 or 2 treatments [ID6363]
Technology appraisal guidance
TBC
Iodine (131I)–apamistamab for treating relapsed or refractory acute myeloid leukaemia before an allogeneic haematopoietic stem cell transplant [ID6355]
Technology appraisal guidance
TBC
Tarlatamab for previously treated advanced small-cell lung cancer [ID6364]
Technology appraisal guidance
11 December 2024
Transcatheter heart valves for transcatheter aortic valve implantation in people with aortic stenosis: Late stage assessment
Health technology evaluation
5 December 2024
Alectinib for adjuvant treatment of ALK-positive non-small-cell lung cancer [ID6368]
Technology appraisal guidance
11 December 2024
Leriglitazone for treating andrenoleukodystrophy [ID3903]
Technology appraisal guidance
TBC
ALXN1840 for treating Wilson disease TS ID 9950
Technology appraisal guidance
TBC
Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer (MA review of TA529) [ID6289]
Technology appraisal guidance
16 October 2024
Digital supported self-management technologies for adults with chronic obstructive pulmonary disease: early value assessment
Health technology evaluation
15 August 2024
Amyotrophic lateral sclerosis - SAR443820 [ID6386]
Technology appraisal guidance
TBC
Selective internal radiation therapy with QuiremSpheres for treating unresectable advanced hepatocellular carcinoma (Partial review of TA688) [ID6376]
Technology appraisal guidance
3 July 2024
Tucatinib with trastuzumab emtansine for treating HER2-positive unresectable or advanced breast cancer after a taxane, trastuzumab or both together [ID6165]
Technology appraisal guidance
TBC
Zanubrutinib for treating relapsed or refractory mantle cell lymphoma after 1 or more treatments [ID6392]
Technology appraisal guidance
TBC
Selpercatinib for previously treated RET fusion-positive advanced non-small-cell lung cancer (MA review of TA760) [ID6293]
Technology appraisal guidance
13 November 2024
Artificial intelligence software to help detect fractures in the emergency department (provisional title)
Health technology evaluation
17 December 2024
Venetoclax with obinutuzumab for untreated chronic lymphocytic leukaemia when there is no 17p deletion or TP53 mutation and FCR (fludarabine, cyclophosphamide, rituximab) or BR (bendamustine, rituximab) are suitable [ID6291]
Technology appraisal guidance
TBC
Sotorasib for previously treated KRAS G12C mutation-positive advanced non-small-cell lung cancer (MA review of TA781) [ID6287]
Technology appraisal guidance
26 February 2025
Cobolimab with dostarlimab and docetaxel for treating advanced non-small-cell lung cancer after anti-PD-L1 treatment and chemotherapy [ID6398]
Technology appraisal guidance
TBC
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