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Showing 1 to 473 of 473

Published guidance, NICE advice and quality standards
TitleReference numberPublishedLast updated
Sinusitis (acute): antimicrobial prescribingNG79
Cataracts in adults: managementNG77
Cystic fibrosis: diagnosis and managementNG78
Hepatitis B (chronic): diagnosis and managementCG165
Tofacitinib for moderate to severe rheumatoid arthritisTA480
Immunosuppressive therapy for kidney transplant in adultsTA481
Immunosuppressive therapy for kidney transplant in children and young peopleTA482
Child maltreatment: when to suspect maltreatment in under 18sCG89
Child abuse and neglectNG76
Autologous chondrocyte implantation for treating symptomatic articular cartilage defects of the kneeTA477
Brentuximab vedotin for treating relapsed or refractory systemic anaplastic large cell lymphomaTA478
Reslizumab for treating severe eosinophilic asthmaTA479
Faltering growth: recognition and management of faltering growth in childrenNG75
Cetuximab and panitumumab for previously untreated metastatic colorectal cancerTA439
Intermediate care including reablementNG74
Type 2 diabetes: prevention in people at high riskPH38
Pembrolizumab for advanced melanoma not previously treated with ipilimumabTA366
Pembrolizumab for treating PD-L1-positive non-small-cell lung cancer after chemotherapyTA428
Pembrolizumab for treating advanced melanoma after disease progression with ipilimumabTA357
Fertility problems: assessment and treatmentCG156
Sorafenib for treating advanced hepatocellular carcinomaTA474
Dimethyl fumarate for treating moderate to severe plaque psoriasisTA475
Paclitaxel as albumin-bound nanoparticles with gemcitabine for untreated metastatic pancreatic cancerTA476
Psoriasis: assessment and managementCG153
Cetuximab for treating recurrent or metastatic squamous cell cancer of the head and neckTA473
Vitamin D: supplement use in specific population groupsPH56
Methylnaltrexone bromide for treating opioid-induced constipation (terminated appraisal)TA468
Idelalisib with ofatumumab for treating chronic lymphocytic leukaemia (terminated appraisal)TA469
Advanced breast cancer: diagnosis and treatmentCG81
Holoclar for treating limbal stem cell deficiency after eye burnsTA467
Pemetrexed for the maintenance treatment of non-small-cell lung cancerTA190
Developmental follow-up of children and young people born pretermNG72
Cabozantinib for previously treated advanced renal cell carcinomaTA463
Baricitinib for moderate to severe rheumatoid arthritisTA466
moorLDI2-BI: a laser doppler blood flow imager for burn wound assessmentMTG2
Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutritionCG32
Adalimumab and dexamethasone for treating non-infectious uveitisTA460
Roflumilast for treating chronic obstructive pulmonary diseaseTA461
Nivolumab for treating relapsed or refractory classical Hodgkin lymphomaTA462
Parkinson's disease in adultsNG71
Constipation in children and young people: diagnosis and managementCG99
Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young peopleTA455
Ustekinumab for moderately to severely active Crohn's disease after previous treatmentTA456
New generation cardiac CT scanners (Aquilion ONE, Brilliance iCT, Discovery CT750 HD and Somatom Definition Flash) for cardiac imaging in people with suspected or known coronary artery disease in whom imaging is difficult with earlier generation CT scannersDG3
Ibrutinib for untreated chronic lymphocytic leukaemia without a 17p deletion or TP53 mutation (terminated appraisal)TA452
Bortezomib for treating multiple myeloma after second or subsequent relapse (terminated appraisal)TA453
Daratumumab with lenalidomide and dexamethasone for treating relapsed or refractory multiple myeloma (terminated appraisal)TA454
Air pollution: outdoor air quality and healthNG70
Eliglustat for treating type 1 Gaucher diseaseHST5
Etelcalcetide for treating secondary hyperparathyroidismTA448
Everolimus and sunitinib for treating unresectable or metastatic neuroendocrine tumours in people with progressive diseaseTA449
Blinatumomab for previously treated Philadelphia-chromosome-negative acute lymphoblastic leukaemiaTA450
Ponatinib for treating chronic myeloid leukaemia and acute lymphoblastic leukaemiaTA451
Multiple frequency bioimpedance devices to guide fluid management in people with chronic kidney disease having dialysisDG29
Obesity: working with local communitiesPH42
Spondyloarthritis in over 16s: diagnosis and managementNG65
Afatinib for treating advanced squamous non-small-cell lung cancer after platinum-based chemotherapy (terminated appraisal)TA444
Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDsTA445
Idiopathic pulmonary fibrosis in adults: diagnosis and managementCG163
Virtual chromoendoscopy to assess colorectal polyps during colonoscopyDG28
Intravenous fluid therapy in adults in hospitalCG174
Pegylated liposomal irinotecan for treating pancreatic cancer after gemcitabineTA440
Ixekizumab for treating moderate to severe plaque psoriasisTA442
Obeticholic acid for treating primary biliary cholangitisTA443
Antisocial behaviour and conduct disorders in children and young people: recognition and managementCG158
Alcohol-use disorders: diagnosis and management of physical complicationsCG100
Sexually transmitted infections: condom distribution schemesNG68
Irritable bowel syndrome in adults: diagnosis and managementCG61
Managing medicines for adults receiving social care in the communityNG67
Panitumumab in combination with chemotherapy for the treatment of metastatic colorectal cancer (terminated appraisal)TA240
Alectinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancer (terminated appraisal)TA438
Patient group directionsMPG2
Bevacizumab for treating EGFR mutation-positive non-small-cell lung cancer (terminated appraisal)TA436
Ibrutinib with bendamustine and rituximab for treating relapsed or refractory chronic lymphocytic leukaemia after systemic therapy (terminated appraisal)TA437
Elotuzumab for previously treated multiple myeloma (terminated appraisal)TA434
Tenofovir alafenamide for treating chronic hepatitis B (terminated appraisal)TA435
Mental health of adults in contact with the criminal justice systemNG66
Ustekinumab for treating active psoriatic arthritisTA340
Ustekinumab for the treatment of adults with moderate to severe psoriasisTA180
Molecular testing strategies for Lynch syndrome in people with colorectal cancerDG27
Migalastat for treating Fabry diseaseHST4
Drug misuse prevention: targeted interventionsNG64
Everolimus for advanced renal cell carcinoma after previous treatmentTA432
Apremilast for treating active psoriatic arthritisTA433
Healthcare-associated infections: prevention and control in primary and community careCG139
HumiGard for preventing inadvertent perioperative hypothermiaMTG31
Osteoporosis: assessing the risk of fragility fractureCG146
Cerebral palsy in under 25s: assessment and managementNG62
Antimicrobial stewardship: changing risk-related behaviours in the general populationNG63
Ibrutinib for previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia with 17p deletion or TP53 mutationTA429
Sofosbuvir–velpatasvir for treating chronic hepatitis CTA430
Pomalidomide for multiple myeloma previously treated with lenalidomide and bortezomibTA427
Organ donation for transplantation: improving donor identification and consent rates for deceased organ donationCG135
Everolimus with exemestane for treating advanced breast cancer after endocrine therapyTA421
Crizotinib for previously treated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancerTA422
Eribulin for treating locally advanced or metastatic breast cancer after 2 or more chemotherapy regimensTA423
Pertuzumab for the neoadjuvant treatment of HER2-positive breast cancerTA424
Dasatinib, nilotinib and high-dose imatinib for treating imatinib-resistant or intolerant chronic myeloid leukaemiaTA425
Dasatinib, nilotinib and imatinib for untreated chronic myeloid leukaemiaTA426
Hypothermia: prevention and management in adults having surgeryCG65
Ticagrelor for preventing atherothrombotic events after myocardial infarctionTA420
XprESS multi sinus dilation system for treating chronic sinusitisMTG30
HIV testing: increasing uptake among people who may have undiagnosed HIVNG60
Recent-onset chest pain of suspected cardiac origin: assessment and diagnosisCG95
Coexisting severe mental illness and substance misuse: community health and social care servicesNG58
Spasticity in under 19s: managementCG145
Dapagliflozin in combination therapy for treating type 2 diabetesTA288
Nivolumab for previously treated advanced renal cell carcinomaTA417
Dapagliflozin in triple therapy for treating type 2 diabetesTA418
Apremilast for treating moderate to severe plaque psoriasisTA419
High-throughput non-invasive prenatal testing for fetal RHD genotypeDG25
Physical health of people in prisonNG57
Psychosis and schizophrenia in children and young people: recognition and managementCG155
Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitorTA415
Elbasvir–grazoprevir for treating chronic hepatitis CTA413
Cobimetinib in combination with vemurafenib for treating unresectable or metastatic BRAF V600 mutation-positive melanomaTA414
Necitumumab for untreated advanced or metastatic squamous non-small-cell lung cancerTA411
Radium-223 dichloride for treating hormone-relapsed prostate cancer with bone metastasesTA412
Crizotinib for untreated anaplastic lymphoma kinase-positive advanced non-small-cell lung cancerTA406
Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitorsTA407
Pegaspargase for treating acute lymphoblastic leukaemiaTA408
Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusionTA409
Talimogene laherparepvec for treating unresectable metastatic melanomaTA410
Multimorbidity: clinical assessment and managementNG56
Harmful sexual behaviour among children and young peopleNG55
Mental health problems in people with learning disabilities: prevention, assessment and managementNG54
Transition between inpatient mental health settings and community or care home settingsNG53
Stable angina: managementCG126
Acute upper gastrointestinal bleeding in over 16s: managementCG141
Bosutinib for previously treated chronic myeloid leukaemiaTA401
Pemetrexed maintenance treatment for non-squamous non-small-cell lung cancer after pemetrexed and cisplatinTA402
Ramucirumab for previously treated locally advanced or metastatic non-small-cell lung cancerTA403
Degarelix for treating advanced hormone-dependent prostate cancerTA404
Trifluridine–tipiracil for previously treated metastatic colorectal cancerTA405
Cabazitaxel for hormone-relapsed metastatic prostate cancer treated with docetaxelTA391
Palliative care for adults: strong opioids for pain reliefCG140
Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimenTA259
Lumacaftor–ivacaftor for treating cystic fibrosis homozygous for the F508del mutationTA398
Azacitidine for treating acute myeloid leukaemia with more than 30% bone marrow blastsTA399
Nivolumab in combination with ipilimumab for treating advanced melanomaTA400
Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicatedTA387
Non-Hodgkin's lymphoma: diagnosis and managementNG52
Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional proceduresCG64
Non-alcoholic fatty liver disease (NAFLD): assessment and managementNG49
Oral health for adults in care homesNG48
Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemiaTA393
Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemiaTA394
Ceritinib for previously treated anaplastic lymphoma kinase positive non-small-cell lung cancerTA395
Trametinib in combination with dabrafenib for treating unresectable or metastatic melanomaTA396
Adalimumab for treating moderate to severe hidradenitis suppurativaTA392
Haematological cancers: improving outcomesNG47
Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetesTA390
ImmunoCAP ISAC 112 for multiplex allergen testingDG24
Sacubitril valsartan for treating symptomatic chronic heart failure with reduced ejection fractionTA388
Topotecan, pegylated liposomal doxorubicin hydrochloride, paclitaxel, trabectedin and gemcitabine for treating recurrent ovarian cancerTA389
Controlled drugs: safe use and managementNG46
Routine preoperative tests for elective surgeryNG45
Workplace health: management practicesNG13
Ruxolitinib for treating disease-related splenomegaly or symptoms in adults with myelofibrosisTA386
Community engagement: improving health and wellbeing and reducing health inequalitiesNG44
Guidance on the use of temozolomide for the treatment of recurrent malignant glioma (brain cancer)TA23
Spectra Optia for automatic red blood cell exchange in people with sickle cell diseaseMTG28
Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemiaTA385
Transition from children's to adults' services for young people using health or social care servicesNG43
Nivolumab for treating advanced (unresectable or metastatic) melanomaTA384
Therapeutic monitoring of TNF-alpha inhibitors in Crohn's disease (LISA-TRACKER ELISA kits, IDKmonitor ELISA kits, and Promonitor ELISA kits)DG22
Fractures (non-complex): assessment and managementNG38
Major trauma: assessment and initial managementNG39
Major trauma: service deliveryNG40
Spinal injury: assessment and initial managementNG41
Skin cancer preventionPH32
Sunlight exposure: risks and benefitsNG34
TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritisTA383
Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicatedTA377
Ramucirumab for treating advanced gastric cancer or gastro–oesophageal junction adenocarcinoma previously treated with chemotherapyTA378
Nintedanib for treating idiopathic pulmonary fibrosisTA379
Panobinostat for treating multiple myeloma after at least 2 previous treatmentsTA380
Eltrombopag for treating severe aplastic anaemia refractory to immunosuppressive therapy (terminated appraisal)TA382
Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failedTA375
Guidance on the use of imatinib for chronic myeloid leukaemiaTA70
Older people: independence and mental wellbeingNG32
Care of dying adults in the last days of lifeNG31
Ciclosporin for treating dry eye disease that has not improved despite treatment with artificial tearsTA369
Bortezomib for previously untreated mantle cell lymphomaTA370
Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritisTA373
Erlotinib and gefitinib for treating non-small-cell lung cancer that has progressed after prior chemotherapyTA374
Oral health promotion: general dental practiceNG30
Transition between inpatient hospital settings and community or care home settings for adults with social care needsNG27
Children's attachment: attachment in children and young people who are adopted from care, in care or at high risk of going into careNG26
Ombitasvir–paritaprevir–ritonavir with or without dasabuvir for treating chronic hepatitis CTA365
Vortioxetine for treating major depressive episodesTA367
Ledipasvir–sofosbuvir for treating chronic hepatitis CTA363
Blood transfusionNG24
VivaScope 1500 and 3000 imaging systems for detecting skin cancer lesionsDG19
Older people with social care needs and multiple long-term conditionsNG22
Developing and updating local formulariesMPG1
Tolvaptan for treating autosomal dominant polycystic kidney diseaseTA358
Idelalisib for treating chronic lymphocytic leukaemiaTA359
Paclitaxel as albumin-bound nanoparticles with carboplatin for untreated non-small-cell lung cancer (terminated appraisal)TA362
Dementia, disability and frailty in later life – mid-life approaches to delay or prevent onsetNG16
Procalcitonin testing for diagnosing and monitoring sepsis (ADVIA Centaur BRAHMS PCT assay, BRAHMS PCT Sensitive Kryptor assay, Elecsys BRAHMS PCT assay, LIAISON BRAHMS PCT assay and VIDAS BRAHMS PCT assay)DG18
Home care: delivering personal care and practical support to older people living in their own homesNG21
Coeliac disease: recognition, assessment and managementNG20
Vedolizumab for treating moderately to severely active Crohn's disease after prior therapyTA352
Bevacizumab for treating relapsed, platinum‑resistant epithelial ovarian, fallopian tube or primary peritoneal cancer (terminated appraisal)TA353
Edoxaban for treating and for preventing deep vein thrombosis and pulmonary embolismTA354
Antimicrobial stewardship: systems and processes for effective antimicrobial medicine useNG15
Naloxegol for treating opioid‑induced constipationTA345
Aflibercept for treating diabetic macular oedemaTA346
Nintedanib for previously treated locally advanced, metastatic, or locally recurrent non‑small‑cell lung cancerTA347
Everolimus for preventing organ rejection in liver transplantationTA348
Secukinumab for treating moderate to severe plaque psoriasisTA350
Cangrelor for reducing atherothrombotic events in people undergoing percutaneous coronary intervention or awaiting surgery requiring interruption of anti‑platelet therapy (terminated appraisal)TA351
Omalizumab for previously treated chronic spontaneous urticariaTA339
Vedolizumab for treating moderately to severely active ulcerative colitisTA342
Apixaban for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolismTA341
Lower urinary tract symptoms in men: managementCG97
Obinutuzumab in combination with chlorambucil for untreated chronic lymphocytic leukaemiaTA343
Challenging behaviour and learning disabilities: prevention and interventions for people with learning disabilities whose behaviour challengesNG11
Violence and aggression: short-term management in mental health, health and community settingsNG10
Rivaroxaban for preventing adverse outcomes after acute management of acute coronary syndromeTA335
Empagliflozin in combination therapy for treating type 2 diabetesTA336
Rifaximin for preventing episodes of overt hepatic encephalopathyTA337
Obesity preventionCG43
Preventing excess weight gainNG7
Excess winter deaths and illness and the health risks associated with cold homesNG6
Medicines optimisation: the safe and effective use of medicines to enable the best possible outcomesNG5
VibraTip for testing vibration perception to detect diabetic peripheral neuropathyMTG22
Safe midwifery staffing for maternity settingsNG4
Bladder cancer: diagnosis and managementNG2
Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapyTA329
Sofosbuvir for treating chronic hepatitis CTA330
Axitinib for treating advanced renal cell carcinoma after failure of prior systemic treatmentTA333
Regorafenib for metastatic colorectal cancer after treatment for metastatic disease (terminated appraisal)TA334
Eculizumab for treating atypical haemolytic uraemic syndromeHST1
Vemurafenib for treating locally advanced or metastatic BRAF V600 mutation‑positive malignant melanomaTA269
Dabigatran etexilate for the treatment and secondary prevention of deep vein thrombosis and/or pulmonary embolismTA327
Fluorouracil chemotherapy: The My5‑FU assay for guiding dose adjustmentDG16
Erythropoiesis‑stimulating agents (epoetin and darbepoetin) for treating anaemia in people with cancer having chemotherapyTA323
Dual‑chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome without atrioventricular blockTA324
Nalmefene for reducing alcohol consumption in people with alcohol dependenceTA325
Imatinib for the adjuvant treatment of gastrointestinal stromal tumoursTA326
The ReCell Spray‑On Skin system for treating skin loss, scarring and depigmentation after burn injuryMTG21
Maternal and child nutritionPH11
Dual‑chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome and/or atrioventricular blockTA88
Gallstone disease: diagnosis and managementCG188
Oral health: local authorities and partnersPH55
Dabrafenib for treating unresectable or metastatic BRAF V600 mutation‑positive melanomaTA321
Alcohol-use disorders: diagnosis, assessment and management of harmful drinking (high-risk drinking) and alcohol dependenceCG115
Physical activity: exercise referral schemesPH54
Drug allergy: diagnosis and managementCG183
Dimethyl fumarate for treating relapsing‑remitting multiple sclerosisTA320
Detecting, managing and monitoring haemostasis: viscoelastometric point‑of‑care testing (ROTEM, TEG and Sonoclot systems)DG13
Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimenTA316
Prasugrel with percutaneous coronary intervention for treating acute coronary syndromesTA317
Ipilimumab for previously untreated advanced (unresectable or metastatic) melanomaTA319
Safe staffing for nursing in adult inpatient wards in acute hospitalsSG1
The geko device for reducing the risk of venous thromboembolismMTG19
Implantable cardioverter defibrillators and cardiac resynchronisation therapy for arrhythmias and heart failureTA314
Canagliflozin in combination therapy for treating type 2 diabetesTA315
Teriflunomide for treating relapsing–remitting multiple sclerosisTA303
Weight management: lifestyle services for overweight or obese adultsPH53
Pressure ulcers: prevention and managementCG179
Afatinib for treating epidermal growth factor receptor mutation-positive locally advanced or metastatic non-small-cell lung cancerTA310
Bortezomib for induction therapy in multiple myeloma before high-dose chemotherapy and autologous stem cell transplantationTA311
Measuring fractional exhaled nitric oxide concentration in asthma: NIOX MINO, NIOX VERO and NObreathDG12
Contraceptive services for under 25sPH51
Needle and syringe programmesPH52
Rituximab in combination with glucocorticoids for treating anti-neutrophil cytoplasmic antibody-associated vasculitisTA308
Aflibercept in combination with irinotecan and fluorouracil-based therapy for treating metastatic colorectal cancer that has progressed following prior oxaliplatin-based chemotherapyTA307
Managing medicines in care homesSC1
Psychosis and schizophrenia in adults: prevention and managementCG178
Domestic violence and abuse: multi-agency workingPH50
Total hip replacement and resurfacing arthroplasty for end-stage arthritis of the hipTA304
Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusionTA305
Pixantrone monotherapy for treating multiply relapsed or refractory aggressive non-Hodgkin's B‑cell lymphomaTA306
Behaviour change: individual approachesPH49
Peginterferon alfa and ribavirin for treating chronic hepatitis C in children and young peopleTA300
Canakinumab for treating systemic juvenile idiopathic arthritis (terminated appraisal)TA302
Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis CTA106
Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis CTA75
Weight management: lifestyle services for overweight or obese children and young peoplePH47
Faecal calprotectin diagnostic tests for inflammatory diseases of the bowelDG11
EGFR‑TK mutation testing in adults with locally advanced or metastatic non-small-cell lung cancerDG9
Intraoperative tests (RD‑100i OSNA system and Metasin test) for detecting sentinel lymph node metastases in breast cancerDG8
Pazopanib for the first-line treatment of advanced renal cell carcinomaTA215
Varicose veins: diagnosis and managementCG168
Aripiprazole for treating moderate to severe manic episodes in adolescents with bipolar I disorderTA292
Aflibercept solution for injection for treating wet age‑related macular degenerationTA294
Rivaroxaban for treating pulmonary embolism and preventing recurrent venous thromboembolismTA287
Mirabegron for treating symptoms of overactive bladderTA290
Falls in older people: assessing risk and preventionCG161
Physical activity: brief advice for adults in primary carePH44
Social anxiety disorder: recognition, assessment and treatmentCG159
Bevacizumab in combination with paclitaxel and carboplatin for first-line treatment of advanced ovarian cancerTA284
Bevacizumab in combination with gemcitabine and carboplatin for treating the first recurrence of platinum-sensitive advanced ovarian cancerTA285
Loxapine inhalation for treating acute agitation and disturbed behaviours associated with schizophrenia and bipolar disorder (terminated appraisal)TA286
Omalizumab for treating severe persistent allergic asthmaTA278
Percutaneous vertebroplasty and percutaneous balloon kyphoplasty for treating osteoporotic vertebral compression fracturesTA279
Antisocial personality disorder: prevention and managementCG77
Colistimethate sodium and tobramycin dry powders for inhalation for treating pseudomonas lung infection in cystic fibrosisTA276
Methylnaltrexone for treating opioid-induced bowel dysfunction in people with advanced illness receiving palliative care (terminated appraisal)TA277
Hepatitis B and C testing: people at risk of infectionPH43
Vinflunine for the treatment of advanced or metastatic transitional cell carcinoma of the urothelial tractTA272
Tadalafil for the treatment of symptoms associated with benign prostatic hyperplasia (terminated appraisal)TA273
Ipilimumab for previously treated advanced (unresectable or metastatic) melanomaTA268
Decitabine for the treatment of acute myeloid leukaemia (terminated appraisal)TA270
Dronedarone for the treatment of non-permanent atrial fibrillationTA197
Physical activity: walking and cyclingPH41
Mannitol dry powder for inhalation for treating cystic fibrosisTA266
Ivabradine for treating chronic heart failureTA267
Depth of anaesthesia monitors – Bispectral Index (BIS), E-Entropy and Narcotrend-Compact MDG6
Social and emotional wellbeing: early yearsPH40
Denosumab for the prevention of skeletal-related events in adults with bone metastases from solid tumoursTA265
Alteplase for treating acute ischaemic strokeTA264
Neutropenic sepsis: prevention and management in people with cancerCG151
SonoVue (sulphur hexafluoride microbubbles) – contrast agent for contrast-enhanced ultrasound imaging of the liverDG5
Mega Soft Patient Return Electrode for use during monopolar electrosurgeryMTG11
Bevacizumab in combination with capecitabine for the first-line treatment of metastatic breast cancerTA263
Rivaroxaban for the treatment of deep vein thrombosis and prevention of recurrent deep vein thrombosis and pulmonary embolismTA261
Sickle cell disease: managing acute painful episodes in hospitalCG143
Lapatinib or trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone-receptor-positive breast cancer that overexpresses HER2TA257
Erlotinib for the first-line treatment of locally advanced or metastatic EGFR-TK mutation-positive non-small-cell lung cancerTA258
Botulinum toxin type A for the prevention of headaches in adults with chronic migraineTA260
Fingolimod for the treatment of highly active relapsing–remitting multiple sclerosisTA254
Pharmalgen for the treatment of bee and wasp venom allergyTA246
Tocilizumab for the treatment of rheumatoid arthritisTA247
Cetuximab, bevacizumab and panitumumab for the treatment of metastatic colorectal cancer after first-line chemotherapy: Cetuximab (monotherapy or combination chemotherapy), bevacizumab (in combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-line chemotherapyTA242
Rituximab for the first-line treatment of stage III-IV follicular lymphomaTA243
Apixaban for the prevention of venous thromboembolism after total hip or knee replacement in adultsTA245
Bevacizumab and cetuximab for the treatment of metastatic colorectal cancerTA118
Service user experience in adult mental health: improving the experience of care for people using adult NHS mental health servicesCG136
Tocilizumab for the treatment of systemic juvenile idiopathic arthritisTA238
Fulvestrant for the treatment of locally advanced or metastatic breast cancerTA239
Healthcare-associated infections: prevention and controlPH36
The EOS 2D/3D imaging systemDG1
Ticagrelor for the treatment of acute coronary syndromesTA236
Mifamurtide for the treatment of osteosarcomaTA235
Bortezomib and thalidomide for the first‑line treatment of multiple myelomaTA228
Dexamethasone intravitreal implant for the treatment of macular oedema secondary to retinal vein occlusionTA229
Agomelatine for the treatment of major depressive episodes (terminated appraisal)TA231
Ambulight PDT for the treatment of non-melanoma skin cancerMTG6
The MIST Therapy system for the promotion of wound healingMTG5
Myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarctionTA73
Erlotinib monotherapy for maintenance treatment of non-small-cell lung cancerTA227
Golimumab for the treatment of rheumatoid arthritis after the failure of previous disease-modifying anti-rheumatic drugsTA225
Rituximab for the first-line maintenance treatment of follicular non-Hodgkin's lymphomaTA226
Cilostazol, naftidrofuryl oxalate, pentoxifylline and inositol nicotinate for the treatment of intermittent claudication in people with peripheral arterial diseaseTA223
Type 2 diabetes prevention: population and community-level interventionsPH35
Golimumab for the treatment of psoriatic arthritisTA220
Coexisting severe mental illness (psychosis) and substance misuse: assessment and management in healthcare settingsCG120
Azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia and acute myeloid leukaemiaTA218
Food allergy in under 19s: assessment and diagnosisCG116
Bevacizumab in combination with a taxane for the first-line treatment of metastatic breast cancerTA214
Bendamustine for the first-line treatment of chronic lymphocytic leukaemiaTA216
Aripiprazole for the treatment of schizophrenia in people aged 15 to 17 yearsTA213
Sedation in under 19s: using sedation for diagnostic and therapeutic proceduresCG112
Clopidogrel and modified-release dipyridamole for the prevention of occlusive vascular eventsTA210
Prucalopride for the treatment of chronic constipation in womenTA211
Bevacizumab in combination with oxaliplatin and either fluorouracil plus folinic acid or capecitabine for the treatment of metastatic colorectal cancerTA212
Unintentional injuries: prevention strategies for under 15sPH29
Unintentional injuries in the home: interventions for under 15sPH30
Unintentional injuries on the road: interventions for under 15sPH31
Trastuzumab for the treatment of HER2-positive metastatic gastric cancerTA208
Imatinib for the treatment of unresectable and/or metastatic gastrointestinal stromal tumoursTA209
Imatinib for the treatment of unresectable and/or metastatic gastro-intestinal stromal tumoursTA86
Bedwetting in under 19sCG111
Denosumab for the prevention of osteoporotic fractures in postmenopausal womenTA204
Bendamustine for the treatment of indolent (low grade) non-Hodgkin's lymphoma that is refractory to rituximab (terminated appraisal)TA206
Temsirolimus for the treatment of relapsed or refractory mantle cell lymphoma (terminated appraisal)TA207
Pregnancy and complex social factors: a model for service provision for pregnant women with complex social factorsCG110
Peginterferon alfa and ribavirin for the treatment of chronic hepatitis CTA200
Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitorTA195
Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritisTA199
Weight management before, during and after pregnancyPH27
Rituximab for the treatment of relapsed or refractory chronic lymphocytic leukaemiaTA193
Capecitabine for the treatment of advanced gastric cancerTA191
Gefitinib for the first-line treatment of locally advanced or metastatic non-small-cell lung cancerTA192
Cardiovascular disease preventionPH25
Alcohol-use disorders: preventionPH24
Human growth hormone (somatropin) for the treatment of growth failure in childrenTA188
Improving outcomes for people with skin tumours including melanomaCSG8
Infliximab and adalimumab for the treatment of Crohn's diseaseTA187
Guidance on the use of glycoprotein IIb/IIIa inhibitors in the treatment of acute coronary syndromesTA47
Donor milk banks: service operationCG93
Topotecan for the treatment of relapsed small-cell lung cancerTA184
Depression in adults with a chronic physical health problem: recognition and managementCG91
Topotecan for the treatment of recurrent and stage IVB cervical cancerTA183
Guidance on the use of electroconvulsive therapyTA59
Sunitinib for the treatment of gastrointestinal stromal tumoursTA179
Pemetrexed for the first-line treatment of non-small-cell lung cancerTA181
Alitretinoin for the treatment of severe chronic hand eczemaTA177
Bevacizumab (first-line), sorafenib (first- and second-line), sunitinib (second-line) and temsirolimus (first-line) for the treatment of advanced and/or metastatic renal cell carcinomaTA178
Tenofovir disoproxil for the treatment of chronic hepatitis BTA173
Rituximab for the first-line treatment of chronic lymphocytic leukaemiaTA174
Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and managementCG84
Rivaroxaban for the prevention of venous thromboembolism after total hip or total knee replacement in adultsTA170
Rehabilitation after critical illness in adultsCG83
Sunitinib for the first-line treatment of advanced and/or metastatic renal cell carcinomaTA169
Amantadine, oseltamivir and zanamivir for the treatment of influenzaTA168
Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherenceCG76
Borderline personality disorder: recognition and managementCG78
Physical activity for children and young peoplePH17
Machine perfusion systems and cold static storage of kidneys from deceased donorsTA165
Infliximab for acute exacerbations of ulcerative colitisTA163
Mental wellbeing in over 65s: occupational therapy and physical activity interventionsPH16
Spinal cord stimulation for chronic pain of neuropathic or ischaemic originTA159
Cardiovascular disease: identifying and supporting people most at risk of dying earlyPH15
Dabigatran etexilate for the prevention of venous thromboembolism after hip or knee replacement surgery in adultsTA157
Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenzaTA158
Routine antenatal anti-D prophylaxis for women who are rhesus D negativeTA156
Entecavir for the treatment of chronic hepatitis BTA153
Telbivudine for the treatment of chronic hepatitis BTA154
Continuous subcutaneous insulin infusion for the treatment of diabetes mellitusTA151
Bevacizumab for the treatment of non-small-cell lung cancer (terminated appraisal)TA148
Carmustine implants for the treatment of recurrent glioblastoma multiforme (terminated appraisal)TA149
Cetuximab for the treatment of locally advanced squamous cell cancer of the head and neckTA145
Adalimumab for the treatment of adults with psoriasisTA146
Physical activity in the workplacePH13
Inhaled corticosteroids for the treatment of chronic asthma in adults and in children aged 12 years and overTA138
Structural neuroimaging in first-episode psychosisTA136
Rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphomaTA137
Infliximab for the treatment of adults with psoriasisTA134
Pemetrexed for the treatment of malignant pleural mesotheliomaTA135
Inhaled corticosteroids for the treatment of chronic asthma in children under the age of 12 yearsTA131
Behaviour change: general approachesPH6
Bortezomib monotherapy for relapsed multiple myelomaTA129
Stapled haemorrhoidopexy for the treatment of haemorrhoidsTA128
Pemetrexed for the treatment of non-small-cell lung cancerTA124
Acutely ill adults in hospital: recognising and responding to deteriorationCG50
Drug misuse in over 16s: opioid detoxificationCG52
Drug misuse in over 16s: psychosocial interventionsCG51
Varenicline for smoking cessationTA123
Faecal incontinence in adults: managementCG49
Carmustine implants and temozolomide for the treatment of newly diagnosed high-grade gliomaTA121
Fludarabine monotherapy for the first-line treatment of chronic lymphocytic leukaemiaTA119
Cinacalcet for the treatment of secondary hyperparathyroidism in patients with end-stage renal disease on maintenance dialysis therapyTA117
Methadone and buprenorphine for the management of opioid dependenceTA114
Naltrexone for the management of opioid dependenceTA115
Gemcitabine for the treatment of metastatic breast cancerTA116
Laparoscopic surgery for colorectal cancerTA105
Etanercept and efalizumab for the treatment of adults with psoriasisTA103
Improving outcomes for people with brain and other central nervous system tumoursCSG10
Docetaxel for the treatment of hormone-refractory metastatic prostate cancerTA101
Capecitabine and oxaliplatin in the adjuvant treatment of stage III (Dukes' C) colon cancerTA100
Improving outcomes for people with sarcomaCSG9
Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis BTA96
Obsessive-compulsive disorder and body dysmorphic disorder: treatmentCG31
Improving outcomes in children and young people with cancerCSG7
HealOzone for the treatment of tooth decay (occlusal pit and fissure caries and root caries)TA92
Guidance on the use of paclitaxel in the treatment of ovarian cancerTA55
Improving outcomes in head and neck cancersCSG6
Dental checks: intervals between oral health reviewsCG19
Laparoscopic surgery for inguinal hernia repairTA83
Tacrolimus and pimecrolimus for atopic eczemaTA82
Frequency of application of topical corticosteroids for atopic eczemaTA81
Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomniaTA77
Fluid-filled thermal balloon and microwave endometrial ablation techniques for heavy menstrual bleedingTA78
Improving supportive and palliative care for adults with cancerCSG4
Pre-hospital initiation of fluid replacement therapy in traumaTA74
Guidance on the use of liquid-based cytology for cervical screeningTA69
Human growth hormone (somatropin) in adults with growth hormone deficiencyTA64
Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancerTA61
Guidance on the use of drugs for early thrombolysis in the treatment of acute myocardial infarctionTA52
Guidance on the use of ultrasound locating devices for placing central venous cathetersTA49
Improving outcomes in urological cancersCSG2
Improving outcomes in breast cancerCSG1
Inhaler devices for routine treatment of chronic asthma in older children (aged 5–15 years)TA38
Guidance on the use of trastuzumab for the treatment of advanced breast cancerTA34
Guidance on the use of fludarabine for B-cell chronic lymphocytic leukaemiaTA29
Guidance on the use of riluzole (Rilutek) for the treatment of motor neurone diseaseTA20
Guidance on the use of inhaler systems (devices) in children under the age of 5 years with chronic asthmaTA10
Guidance on the extraction of wisdom teethTA1

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